CCR2 Antibody (475301) [Fluorescein]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CCR2, also known as CD192, is a 38 kDa 7TM chemokine receptor that preferentially binds CCL2, CCL7, and CCL13. CCR2 is expressed by multiple hematopoietic cells, endothelial cells, fibroblasts, neurons, and smooth muscle cells. It functions as an HIV fusion co-factor and facilitates T cell recruitment during inflammation. Two alternate splice forms (CCR2A and CCR2B) differ only by the addition of 14 amino acids to the intracellular carboxyl terminal. Mouse CCR2 shares 67% and 95% aa sequence identity with human and rat CCR2, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: Flow Cytometry.

Showing Publications 1 - 10 of 19. Show All 19 Publications. Collapse Publications.

Publications using FAB5538F	Applications	Species
Chandra B, Shiny N, Glenn B et al. Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy. Elife. 2022-08-16 [PMID: 35972072]
Chandra B, Shiny N, Glenn B et al. Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy. Elife. 8/16/2022 [PMID: 35972072]
Tariq Hamid, Yuanyuan Xu, Mohamed Ameen Ismahil, Gregg Rokosh, Miki Jinno, Guihua Zhou et al. Cardiac Mesenchymal Stem Cells Promote Fibrosis and Remodeling in Heart Failure: Role of PDGF Signaling JACC: Basic to Translational Science 5/1/2022 [PMID: 35663630]
S Da Mesquit, J Herz, M Wall, T Dykstra, KA de Lima, GT Norris, N Dabhi, T Kennedy, W Baker, J Kipnis Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and &beta-amyloid pathology Science Advances, 2021-05-21;7(21):. 2021-05-21 [PMID: 34020948] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
S Da Mesquit, Z Papadopoul, T Dykstra, L Brase, FG Farias, M Wall, H Jiang, CD Kodira, KA de Lima, J Herz, A Louveau, DH Goldman, AF Salvador, S Onengut-Gu, E Farber, N Dabhi, T Kennedy, MG Milam, W Baker, I Smirnov, SS Rich, Dominantly, BA Benitez, CM Karch, RJ Perrin, M Farlow, JP Chhatwal, DM Holtzman, C Cruchaga, O Harari, J Kipnis Meningeal lymphatics affect microglia responses and anti-A&beta immunotherapy Nature, 2021-04-28;0(0):. 2021-04-28 [PMID: 33911285] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
C Youssif, M Cubillos-R, M Comalada, E Llonch, C Perna, N Djouder, AR Nebreda Myeloid p38? signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis EMBO Mol Med, 2018-07-01;0(0):. 2018-07-01 [PMID: 29907597] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Y Kaneko, T Cho, Y Sato, K Goto, S Yamamoto, S Goto, MP Madaio, I Narita Attenuated Macrophage Infiltration in Glomeruli of Aged Mice Resulting in Ameliorated Kidney Injury in Nephrotoxic Serum Nephritis J. Gerontol. A Biol. Sci. Med. Sci., 2018-08-10;0(0):. 2018-08-10 [PMID: 29415117] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
E Kaufmann, J Sanz, JL Dunn, N Khan, LE Mendonça, A Pacis, F Tzelepis, E Pernet, A Dumaine, JC Grenier, F Mailhot-Lé, E Ahmed, J Belle, R Besla, B Mazer, IL King, A Nijnik, CS Robbins, LB Barreiro, M Divangahi BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis Cell, 2018-01-11;172(1):176-190.e19. 2018-01-11 [PMID: 29328912] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
X Wu, KK Dayanand, RP Thylur, CC Norbury, DC Gowda Small molecule-based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes J. Biol. Chem., 2017-07-05;0(0):. 2017-07-05 [PMID: 28679535] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Guerra E, Lee C, Specht C, Yadav B, Huang H, Akalin A, Huh J, Mueller C, Levitz S Central Role of IL-23 and IL-17 Producing Eosinophils as Immunomodulatory Effector Cells in Acute Pulmonary Aspergillosis and Allergic Asthma. PLoS Pathog, 2017-01-17;13(1):e1006175. 2017-01-17 [PMID: 28095479] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Innate Allorecognition Results in Rapid Accumulation of Monocyte-Derived Dendritic Cells J Immunol, 2016-07-29;0(0):. 2016-07-29 [PMID: 27474076] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
S Wattananit, D Tornero, N Graubardt, T Memanishvi, E Monni, J Tatarishvi, G Miskinyte, R Ge, H Ahlenius, O Lindvall, M Schwartz, Z Kokaia Monocyte-Derived Macrophages Contribute to Spontaneous Long-Term Functional Recovery after Stroke in Mice J Neurosci, 2016-04-13;36(15):4182-95. 2016-04-13 [PMID: 27076418] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Levy N, Milikovsky D, Baranauskas G, Vinogradov E, David Y, Ketzef M, Abutbul S, Weissberg I, Kamintsky L, Fleidervish I, Friedman A, Monsonego A Differential TGF-beta Signaling in Glial Subsets Underlies IL-6-Mediated Epileptogenesis in Mice. J Immunol, 2015-07-01;195(4):1713-22. 2015-07-01 [PMID: 26136430] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Viana I, de Almeida M, Lins M, dos Santos Reis M, de Araujo Vieira L, Smaniotto S Combined effect of insulin-like growth factor-1 and CC chemokine ligand 2 on angiogenic events in endothelial cells. PLoS ONE, 2015-04-01;10(4):e0121249. 2015-04-01 [PMID: 25830234] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, Bentires-Alj M Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis. Nature, 2014-10-22;515(7525):130-3. 2014-10-22 [PMID: 25337873] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Neal L, Knoll L Toxoplasma gondii profilin promotes recruitment of Ly6Chi CCR2+ inflammatory monocytes that can confer resistance to bacterial infection. PLoS Pathog, 2014-06-12;10(6):e1004203. 2014-06-12 [PMID: 24945711] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Nie P, Li D, Hu L, Jin S, Yu Y, Cai Z, Shao Q, Shen J, Yi J, Xiao H, Shen L, He B Atorvastatin improves plaque stability in ApoE-knockout mice by regulating chemokines and chemokine receptors. PLoS ONE, 2014-05-09;9(5):e97009. 5/9/2014 [PMID: 24816562]
Heim , Cortney, Vidlak , Debbie, Scherr , Tyler D, Kozel , Jessica, Holzapfel , Melissa, Muirhead , David E, Kielian , Tammy Myeloid-derived suppressor cells contribute to Staphylococcus aureus orthopedic biofilm infection. J Immunol, 2014-03-19;192(8):3778-92. 2014-03-19 [PMID: 24646737] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Simons D, Oh S, Kropf E, Aitken M, Garcia V, Basehoar A, Caton A Autoreactive Th1 cells activate monocytes to support regional Th17 responses in inflammatory arthritis. J Immunol, 2013-02-18;190(7):3134-41. 2013-02-18 [PMID: 23420889] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Show All 19 Publications. Collapse Publications.

Array FAB5538F

• CCR2 Antibodies
• CCR2 ELISA Kit
• CCR2 Lysates
• CCR2 Proteins