CCL17/TARC Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CCL17 is a novel CC chemokine identified using a signal sequence trap method. CCL17 cDNA encodes a highly basic 94 amino acid (aa)residue precursor protein with a 23 aa residue signal peptide that is cleaved to generate the 71 aa residue mature secreted protein. Among CC chemokine family members, CCL17 has approximately 24-29% amino acid sequence identity with RANTES, MIP-1 alpha , MIP-1 beta , MCP-1, MCP-2, MCP-3, and I-309. The gene for human CCL17 has been mapped to chromosome 16q13 rather than chromosome 17 where the genes for many human CC chemokines are clustered. CCL17 is constitutively expressed in thymus, and at a lower level in lung, colon, and small intestine. CCL17 is also transiently expressed in stimulated peripheral blood mononuclear cells. Recombinant CCL17 has been shown to be chemotactic for T cell lines but not monocytes or neutrophils. CCL17 was identified to be a specific functional ligand for CCR4, a receptor that is selectively expressed on T cells.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 5 applications: ICC, IHC, IHC-Fr, IHC-P, Western Blot.

Showing Publications 1 - 10 of 13. Show All 13 Publications. Collapse Publications.

Publications using AF364	Applications	Species
J Driessen, MJ Kersten, L Visser, A van den Be, SH Tonino, JM Zijlstra, PJ Lugtenburg, F Morschhaus, M Hutchings, S Amorim, T Gastinne, M Nijland, GJC Zwezerijne, R Boellaard, HCW de Vet, AIJ Arens, R Valkema, RDK Liu, EEE Drees, D de Jong, WJ Plattel, A Diepstra, HOVON Lune Prognostic value of TARC and quantitative PET parameters in relapsed or refractory Hodgkin lymphoma patients treated with brentuximab vedotin and DHAP Leukemia, 2022-10-14;0(0):. 2022-10-14 [PMID: 36241696] (IHC, Human)	IHC	Human
YH Hsieh, WC Wang, TW Hung, CC Lee, JP Tsai C-C Motif Chemokine Ligand-17 as a Novel Biomarker and Regulator of Epithelial Mesenchymal Transition in Renal Fibrogenesis Cells, 2021-11-29;10(12):. 2021-11-29 [PMID: 34943853] (Western Blot, Human)	Western Blot	Human
Michael Kvorjak, Yasmine Ahmed, Michelle L. Miller, Raahul Sriram, Claudia Coronnello, Jana G. Hashash et al. Cross-talk between Colon Cells and Macrophages Increases ST6GALNAC1 and MUC1-sTn Expression in Ulcerative Colitis and Colitis-Associated Colon Cancer Cancer Immunology Research 2/1/2020 [PMID: 31831633]
Rump L, Mattey D, Kehoe O, Middleton J An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium. Cytokine, 2017-09-01;97(0):133-140. 2017-09-01 [PMID: 28648867] (IHC-Fr, Human)	IHC-Fr	Human
Y Yuan, J Kluiver, J Koerts, D de Jong, B Rutgers, FRA Razak, M Terpstra, B Plaat, IM Nolte, A Diepstra, L Visser, K Kok, A van den Be miR-24-3p Is Overexpressed in Hodgkin Lymphoma and Protects Hodgkin and Reed-Sternberg Cells from Apoptosis Am. J. Pathol., 2017-04-20;0(0):. 2017-04-20 [PMID: 28432871] (IHC, Human)	IHC	Human
Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J. Immunol., 2010-02-17;184(6):2886-98. 2010-02-17 [PMID: 20164417] (IHC-P, Human)	IHC-P	Human
Kishi M, Miyazaki Y, Jinta T, Furusawa H, Ohtani Y, Inase N, Yoshizawa Y Pathogenesis of cBFL in common with IPF? Correlation of IP-10/TARC ratio with histological patterns. Thorax, 2008-02-14;63(9):810-6. 2008-02-14 [PMID: 18276722] (IHC-P, Human)	IHC-P	Human
Ma Y, Visser L, Roelofsen H, de Vries M, Diepstra A, van Imhoff G, van der Wal T, Luinge M, Alvarez-Llamas G, Vos H, Poppema S, Vonk R, Van Den Berg A Proteomics analysis of Hodgkin lymphoma: identification of new players involved in the cross-talk between HRS cells and infiltrating lymphocytes. Blood, 2007-12-10;111(4):2339-46. 2007-12-10 [PMID: 18070985] (IHC-P, Human)	IHC-P	Human
Heijink IH, Kies PM, Kauffman HF, Postma DS, van Oosterhout AJ, Vellenga E Down-regulation of E-cadherin in human bronchial epithelial cells leads to epidermal growth factor receptor-dependent Th2 cell-promoting activity. J. Immunol., 2007-06-15;178(12):7678-85. 2007-06-15 [PMID: 17548604] (ICC, Human)	ICC	Human
Rust R, Kluiver J, Visser L, Harms G, Blokzijl T, Kamps W, Poppema S, Van Den Berg A Gene expression analysis of dendritic/Langerhans cells and Langerhans cell histiocytosis. J. Pathol., 2006-08-01;209(4):474-83. 2006-08-01 [PMID: 16718746] (IHC, Human)	IHC	Human
Vestergaard C, Johansen C, Christensen U, Just H, Hohwy T, Deleuran M TARC augments TNF-alpha-induced CTACK production in keratinocytes. Exp. Dermatol., 2004-09-01;13(9):551-7. 2004-09-01 [PMID: 15335355] (Human)		Human
Ohshima K, Karube K, Kawano R, Tsuchiya T, Suefuji H, Yamaguchi T, Suzumiya J, Kikuchii M Classification of distinct subtypes of peripheral T-cell lymphoma unspecified, identified by chemokine and chemokine receptor expression: Analysis of prognosis. Int. J. Oncol., 2004-09-01;25(3):605-13. 2004-09-01 [PMID: 15289861] (IHC-P, Human)	IHC-P	Human
Maggio EM, Van Den Berg A, Visser L, Diepstra A, Kluiver J, Emmens R, Poppema S Common and differential chemokine expression patterns in rs cells of NLP, EBV positive and negative classical Hodgkin lymphomas. Int. J. Cancer, 2002-06-10;99(5):665-72. 2002-06-10 [PMID: 12115499] (ICC, IHC, Human)	ICC, IHC	Human
Show All 13 Publications. Collapse Publications.

Array AF364

• CCL17/TARC Antibodies
• CCL17/TARC Antibody Pair
• CCL17/TARC Lysate
• CCL17/TARC Proteins
• CCL17/TARC Proteins and Enzymes
• CCL17/TARC ELISAs