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11 beta-HSD1 Antibody

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Western Blot: 11 beta-HSD1 Antibody [NBP3-13393] - Rat tissue extract (50 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with 11 beta-HSD1 antibody (NBP3-13393) diluted at 1:1000. The HRP-conjugated ...read more
Immunohistochemistry-Paraffin: 11 beta-HSD1 Antibody [NBP3-13393] - 11 beta-HSD1 antibody detects 11 beta-HSD1 protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded rat muscle. 11 beta-HSD1 ...read more
Western Blot: 11 beta-HSD1 Antibody [NBP3-13393] - Mouse tissue extract (50 ug) were separated by 12% SDS-PAGE, and the membrane was blotted with 11 beta-HSD1 antibody (NBP3-13393) diluted at 1:1000. The HRP-conjugated ...read more
Immunohistochemistry-Paraffin: 11 beta-HSD1 Antibody [NBP3-13393] - 11 beta-HSD1 antibody detects 11 beta-HSD1 protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. 11 beta-HSD1 ...read more

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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11 beta-HSD1 Antibody Summary

Description
Centrifuge briefly prior to opening.
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of mouse 11 beta-HSD1. The exact sequence is proprietary.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HSD11B1
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7), 20% Glycerol
Preservative
0.025% Proclin 300
Purity
Antigen Affinity-purified

Alternate Names for 11 beta-HSD1 Antibody

  • 11 betaHSD1
  • 11 beta-HSD1
  • 11-beta-hydroxysteroid dehydrogenase 1
  • EC 1.1.1
  • EC 1.1.1.146
  • HDL
  • HSD11B1
  • HSD11HSD11B
  • HSD11LMGC13539
  • hydroxysteroid (11-beta) dehydrogenase 1
  • member 1
  • SDR26C1

Background

HSD11B1 is encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HSD11B1