Vanilloid R1/TRPV1 Antibody - BSA Free

TRPV1 (transient receptor potential cation channel subfamily V member 1, capsaicin receptor, vanilloid receptor, Vr1) is a polymodal nociceptor activated by heat, vanilloids (capsaicin), and protons. It is primarily expressed in the dorsal root ganglia and peripheral nerve endings. TRPV1 antagonists are a potential therapeutic target for many suffering chronic physical and neuropathic pain. However, due to its other role in the regulation of body temperature, these therapies are currently experiencing a barrier. On the other hand, TRPV1 agonists can be used to desensitize nerves after activation, thereby reducing pain. The research around TRPV1 is broad, where it is studied in fields such as anxiety, pain, oxidative stress, taste, inflammation, depression, respiratory disease, and various psychiatric disorders.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 2 applications: ICC/IF, WB.

Showing Publications 1 - 10 of 12. Show All 12 Publications. Collapse Publications.

Publications using NBP1-97417	Applications	Species
Wang SH, Huang SH, Hsieh MC et al. Hyperbaric Oxygen Therapy Alleviates Paclitaxel-Induced Peripheral Neuropathy Involving Suppressing TLR4-MyD88-NF-?B Signaling Pathway International journal of molecular sciences 2023-03-11 [PMID: 36982452] (WB, ICC/IF, Rat)	WB, ICC/IF	Rat
Bla�evi? T, Ciotu CI, Gold-Binder M et al. Cultured rat aortic vascular smooth muscle cells do not express a functional TRPV1 PloS one 2023-02-14 [PMID: 36787302] (Rat)		Rat
Schwab AJ, Ebert AD. Neurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson's Disease-Related LRRK2 G2019S Mutation. Stem Cell Reports. 2015-12-08 [PMID: 26651604] (ICC/IF, Human)	ICC/IF	Human
Billeter AT, Galbraith N, Walker S et al. TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response Surgery. 2015-06-05 [PMID: 26054320]
Zeng H, Li P, Zhou D et al. Sophocarpine inhibits TRP channels to produce anti-pruritic and analgesic effects in a mouse model of inflammatory itch and pain bioRxiv 2023-10-16 (WB, Mouse)	WB	Mouse
Lambiase A, Mallone F, Sacchetti M et al. Patients with neurotrophic keratitis demonstrate alterations in ocular surface expression of transient receptor potential (TRP) channels The ocular surface 2023-11-07 [PMID: 37939847] (WB, Human)	WB	Human
Rossi F, Tortora C, Di Martino M et al. Alteration of osteoclast activity in childhood cancer survivors: Role of iron and of CB2/TRPV1 receptors PloS one 2022-07-21 [PMID: 35862357]
Wamba B, Ghosh P, Mbaveng A, et al. Botanical from Piper capense Fruit Can Help to Combat the Melanoma as Demonstrated by In Vitro and In Vivo Studies Evid Based Complement Alternat Med 2021-05-19 [PMID: 34007300]
Lee BM, Jang Y, Park G et al. Dexmedetomidine modulates transient receptor potential vanilloid subtype 1 Biochem. Biophys. Res. Commun. 2019-11-30 [PMID: 31796207] (ICC/IF, Mouse)	ICC/IF	Mouse
Roman K, Hall C, Schaeffer AJ, Thumbikat P TRPV1 in experimental autoimmune prostatitis Prostate 2019-10-01 [PMID: 31573117] (WB, Mouse)	WB	Mouse
Jeong JH, Lee DK, Liu SM et al. Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake PLoS Biol. 2018-04-01 [PMID: 29689050]
Schwab AJ, Ebert AD. Sensory neurons do not induce motor neuron loss in a human stem cell model of spinal muscular atrophy. PLoS ONE 2014-07-24 [PMID: 25054590] (ICC/IF, Human) Details: TRPV1 antibody used for ICC-IF on induced pluripotent stem cells (iPSCs) - 4% paraformaldehyde /PFA -20 min RT fixation, 0.2% Triton X-100 - 30 min RT permeablization, blocking with 5% normal goat serum.	ICC/IF	Human
Show All 12 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Giulia Di Cristina	IHC-P	Other	07/19/2016	View Summary Application Immunohistochemistry-Paraffin Sample Tested 10 µm paraffin transversal sections of the arm of Octopus vulgaris Species Other Lot A-2

Array NBP1-97417

• Vanilloid R1/TRPV1 Antibodies
• Vanilloid R1/TRPV1 ELISA Kits
• Vanilloid R1/TRPV1 Lysates
• Vanilloid R1/TRPV1 Proteins