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Vanilloid R1/TRPV1 Antibody [CoraFluor™ 1]

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Product Details

Summary
Reactivity Hu, Mu, Rt, In, PmSpecies Glossary
Applications WB, ICC/IF, ICC/IF, IHC (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-97417AF350
Alexa Fluor 405
NBP1-97417AF405
Alexa Fluor 488
NBP1-97417AF488
Alexa Fluor 532
NBP1-97417AF532
Alexa Fluor 594
NBP1-97417AF594
Alexa Fluor 647
NBP1-97417AF647
Alexa Fluor 700
NBP1-97417AF700
Alexa Fluor 750
NBP1-97417AF750
Allophycocyanin
NBP1-97417APC
Biotin
NBP1-97417B
DyLight 350
NBP1-97417UV
DyLight 405
NBP1-97417V
DyLight 488
NBP1-97417G
DyLight 550
NBP1-97417R
DyLight 594
NBP1-97417DL594
DyLight 650
NBP1-97417C
DyLight 680
NBP1-97417FR
DyLight 755
NBP1-97417IR
FITC
NBP1-97417F
HRP
NBP1-97417H
Janelia Fluor 525
NBP1-97417JF525
Janelia Fluor 549
NBP1-97417JF549
Janelia Fluor 585
NBP1-97417JF585
Janelia Fluor 635
NBP1-97417JF635
Janelia Fluor 646
NBP1-97417JF646
Janelia Fluor 669
NBP1-97417JF669
PE
NBP1-97417PE
PerCP
NBP1-97417PCP
Unconjugated
NBP1-97417
mFluor Violet 450 SE
NBP1-97417MFV450
mFluor Violet 500 SE
NBP1-97417MFV500
mFluor Violet 610 SE
NBP1-97417MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-97417
BSA Free
NBP1-97417SS
BSA Free
NBP1-97417
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Vanilloid R1/TRPV1 Antibody [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
A synthetic peptide made to an N-terminal portion of the rat TRPV1 protein (between residues 1-50) [Uniprot: O35433]
Localization
Multi-pass membrane protein. Note: Mostly, but not exclusively expressed in post-synaptic dendritic spines.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRPV1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Reactive to Octopus vulgaris.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Vanilloid R1/TRPV1 Antibody [CoraFluor™ 1]

  • Capsaicin Receptor
  • Osm-9-like TRP channel 1
  • OTRPC1
  • transient receptor potential cation channel subfamily V member 1
  • transient receptor potential cation channel, subfamily V, member 1
  • transient receptor potential vanilloid 1a
  • transient receptor potential vanilloid 1b
  • TRPV1
  • Vanilloid R1
  • Vanilloid receptor 1
  • vanilloid receptor subtype 1
  • VanilloidR1
  • VR1
  • VR1DKFZp434K0220

Background

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TRPV1