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Vanilloid R1/TRPV1 Antibody [DyLight 405]

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Product Details

Summary
Reactivity Hu, Mu, Rt, In, PmSpecies Glossary
Applications WB, ICC/IF, ICC/IF, IHC (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 405

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Vanilloid R1/TRPV1 Antibody [DyLight 405] Summary

Immunogen
A synthetic peptide made to an N-terminal portion of the rat TRPV1 protein (between residues 1-50) [Uniprot: O35433]
Localization
Multi-pass membrane protein. Note: Mostly, but not exclusively expressed in post-synaptic dendritic spines.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRPV1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Reactive to Octopus vulgaris.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Vanilloid R1/TRPV1 Antibody [DyLight 405]

  • Capsaicin Receptor
  • Osm-9-like TRP channel 1
  • OTRPC1
  • transient receptor potential cation channel subfamily V member 1
  • transient receptor potential cation channel, subfamily V, member 1
  • transient receptor potential vanilloid 1a
  • transient receptor potential vanilloid 1b
  • TRPV1
  • Vanilloid R1
  • Vanilloid receptor 1
  • vanilloid receptor subtype 1
  • VanilloidR1
  • VR1
  • VR1DKFZp434K0220

Background

TRPV1 (transient receptor potential cation channel subfamily V member 1, capsaicin receptor, vanilloid receptor, Vr1) is a polymodal nociceptor activated by heat, vanilloids (capsaicin), and protons. It is primarily expressed in the dorsal root ganglia and peripheral nerve endings. TRPV1 antagonists are a potential therapeutic target for many suffering chronic physical and neuropathic pain. However, due to its other role in the regulation of body temperature, these therapies are currently experiencing a barrier. On the other hand, TRPV1 agonists can be used to desensitize nerves after activation, thereby reducing pain. The research around TRPV1 is broad, where it is studied in fields such as anxiety, pain, oxidative stress, taste, inflammation, depression, respiratory disease, and various psychiatric disorders.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Vanilloid R1/TRPV1 Antibody (NBP1-97417V) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TRPV1