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Tubby Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: Tubby Antibody [NBP1-87824] - Staining of human cell line U-251 MG shows localization to nucleoli & centrosome. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Tubby Antibody [NBP1-87824] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Tubby Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: QSDHAQDAGETAAGGGERPSGQDLRATMQRKGISSSMSFDEDEEDEEENSSSSSQLNSNTRPSSATSRKSVREAASAPSPTAPEQPVDVEVQDLEEFALRPAPQGITIKCRITRDKK
Predicted Species
Mouse (91%), Rat (92%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TUB
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
Tubby Protein (NBP1-87824PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Tubby Antibody

  • RD5
  • RDOB
  • tubby (mouse) homolog
  • tubby homolog (mouse)
  • Tubby Homolog
  • tubby homologue
  • tubby protein homolog
  • Tubby

Background

Tub-1 protein is C. elegans tubby homolog, required for normal sensory behavior. It is expressed in ciliated neurons and undergoes both cilated and dendritic transport. It has been shown to be involved in regulating fat storage, most likely by modulating transport, sensing, or responding to signals in ciliated neurons. It has also been shown to play a role in regulating life span, but by a different mechanism than fat storage regulation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for Tubby Antibody (NBP1-87824) (0)

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Secondary Antibodies

 

Isotype Controls

Additional Tubby Products

Array NBP1-87824

Research Areas for Tubby Antibody (NBP1-87824)

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Blogs on Tubby.

Auditory Infographic: Can you hear me now?
The auditory process involves several structures of the ear to convert sound waves into information that is processed by our brain. Learn more about the auditory process in our infographic below. Novus Biologicals offers reagents mentioned in the inf...  Read full blog post.

Can Tubby Make You Tubby?
The TUB gene, which encodes for the protein Tubby, is evolutionarily conserved in human, chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito, C. elegans, and rice. The gene derives its name from its role in metabolism; mice with a m...  Read full blog post.

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Bioinformatics

Gene Symbol TUB