Steppan J, Wang H, Nandakumar K et al. LOXL2 inhibition ameliorates pulmonary artery remodeling in pulmonary hypertension bioRxiv 2023-10-29 [PMID: 37961202] (WB)
Details:
Dilution 1:5000 |
WB |
|
| Chua B, Ferry L, Domrane C et al. E4F1 and ZNF148 are transcriptional activators of the A57C and wildtypeTERTpromoter bioRxiv 2023-01-15 [PMID: 37918959] (WB, Human) |
WB |
Human |
| Arumugam TV, Alli-Shaik A, Liehn EA et al. Multiomics analyses reveal dynamic bioenergetic pathways and functional remodeling of the heart during intermittent fasting Elife 2023-09-28 [PMID: 37769126] |
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Kalinin S, Feinstein DL Astrocyte lipocalin-2 modestly effects disease severity in a mouse model of multiple sclerosis while reducing mature oligodendrocyte protein and mRNA expression Neuroscience letters 2023-09-23 [PMID: 37748675] (IHC-P, Mouse)
Details:
1:300 IHC-P dilution |
IHC-P |
Mouse |
| Guo D, Yu M, Guo H et al. Panax notoginseng saponins inhibits oxidative stress- induced human nucleus pulposus cell apoptosis and delays disc degeneration in vivo and in vitro Journal of ethnopharmacology 2023-09-15 [PMID: 37716491] (WB, Human) |
WB |
Human |
| Yasuhara J, Manivannan SN, Majumdar U et al. Novel pathogenic GATA6 variant associated with congenital heart disease, diabetes mellitus and necrotizing enterocolitis Pediatric research 2023-09-12 [PMID: 37700164] |
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| Huang CL, Chen DY, Tzang CC et al. Celastrol attenuates human parvovirus B19 NS1?induced NLRP3 inflammasome activation in macrophages Molecular Medicine Reports 2023-08-31 [PMID: 37654202] (WB) |
WB |
|
| Cheng W, Lawson C, Liu H et al. Exploration of Mediators Associated with Myocardial Remodelling in Feline Hypertrophic Cardiomyopathy Animals 2023-06-26 [PMID: 37443910] (WB, Feline) |
WB |
Feline |
| Kong MJ, Han SJ, Seu SY et al. Shortening of primary cilia length is associated with urine concentration in the kidneys Kidney Research and Clinical Practice 2023-05-31 [PMID: 37313611] (WB) |
WB |
|
| Natsagdorj A, Izumi K, Hiratsuka K et al. The CCL2-CCR2 Axis Contributes to Migration of Cabazitaxel-resistant Prostate Cancer Cells Anticancer research 2023-06-01 [PMID: 37247914] |
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| Abe T, Sato T, Murotomi K Sudachitin and Nobiletin Stimulate Lipolysis via Activation of the cAMP/PKA/HSL Pathway in 3T3-L1 Adipocytes Foods (Basel, Switzerland) 2023-05-10 [PMID: 37238764] (WB, Mouse) |
WB |
Mouse |
| Wen YC, Tram VTN, Chen WH et al. CHRM4/AKT/MYCN upregulates interferon alpha-17 in the tumor microenvironment to promote neuroendocrine differentiation of prostate cancer Cell death & disease 2023-05-04 [PMID: 37142586] (ChIP, Human) |
ChIP |
Human |
| Jankauskas SS, Mone P, Avvisato R et al. miR-181c targets Parkin and SMAD7 in human cardiac fibroblasts: Validation of differential microRNA expression in patients with diabetes and heart failure with preserved ejection fraction Mechanisms of ageing and development 2023-04-26 [PMID: 37116731] |
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| Park YR, Kong MJ, Noh MR, Park KM Rac1 inhibition protects the kidney against kidney ischemia/reperfusion through the inhibition of macrophage migration The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2023-05-01 [PMID: 37078299] (WB, Mouse) |
WB |
Mouse |
| Azman MS, Alard EL, Dodel M et al. An ERK1/2-driven RNA-binding switch in nucleolin drives ribosome biogenesis and pancreatic tumorigenesis downstream of RAS oncogene The EMBO journal 2023-04-11 [PMID: 37039106] (WB, Mouse) |
WB |
Mouse |
| Wang H, Poe A, Martinez Yus M et al. Lysyl oxidase-like 2 processing by factor Xa modulates its activity and substrate preference Communications biology 2023-04-07 [PMID: 37029269] (WB) |
WB |
|
| Yeung CC, Olesen AT, Wilson R et al. Proteome profiles of intramuscular connective tissue: influence of aging and physical training Journal of applied physiology (Bethesda, Md. : 1985) 2023-05-01 [PMID: 36995911] |
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| Bonham C, Mandati V, Singh R et al. Coupling substrate-trapping with proximity-labeling to identify protein tyrosine phosphatase PTP1B signaling networks Journal of Biological Chemistry 2023-03-01 [PMID: 36871762] |
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| Matos Guedes H, Fonseca-Martins A, Liang y et al. Leishmania amazonensis infection induces PD-L1 expression on dendritic cells in an mTor-dependent manner and impairs Th1 responses in vitro and in vivo bioRxiv Feb 18 2022 (WB, Mouse) |
WB |
Mouse |
| Jankauskas SS, Kansakar U, Sardu C et al. COVID-19 Causes Ferroptosis and Oxidative Stress in Human Endothelial Cells Antioxidants (Basel, Switzerland) 2023-01-31 [PMID: 36829885] (WB, Human) |
WB |
Human |
| Aggarwal M. 2,2-Diphenethyl Isothiocyanate Enhances Topoisomerase Inhibitor-Induced Cell Death and Suppresses Multi-Drug Resistance 1 in Breast Cancer Cells Cancers (Basel) 2023-02-01 [PMID: 36765888] |
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| Kim EJ, Yoon JU, Kim CH et al. Lidocaine inhibits osteogenic differentiation of human dental pulp stem cells in vitro The Journal of international medical research 2023-02-01 [PMID: 36748349] (WB, Human) |
WB |
Human |
| Yamamoto Y, Kurokawa M, Ogawa T et al. Involvement of gap junctions in the increased contraction of bovine oviducts at pre-ovulation observed in vitro Reproduction (Cambridge, England) 2023-03-01 [PMID: 36598933] |
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| Kalkan H, Pagano E, Paris D et al. Targeting gut dysbiosis against inflammation and impaired autophagy in Duchenne muscular dystrophy EMBO Molecular Medicine 2023-03-08 [PMID: 36594243] (WB, B/N) |
WB, B/N |
|
| Dufour D, Dumontet T, Sahut-Barnola I et al. Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation Research Square 2022-03-18 [PMID: 36543805] (WB, Mouse) |
WB |
Mouse |
| Abe T Timing of Medium-Chain Triglyceride Consumption Modulates Effects in Mice with Obesity Induced by a High-Fat High-Sucrose Diet Nutrients 2022-12-01 [PMID: 36501131] (WB, Mouse) |
WB |
Mouse |
| Abe T Timing of Medium-Chain Triglyceride Consumption Modulates Effects in Mice with Obesity Induced by a High-Fat High-Sucrose Diet Nutrients 2022-12-01 [PMID: 36501131] (WB, Mouse) |
WB |
Mouse |
| Masala N, Pofahl M, Haubrich AN et al. Targeting aberrant dendritic integration to treat cognitive comorbidities of epilepsy Brain 2023-06-01 [PMID: 36448426] (B/N, WB) |
B/N, WB |
|
| Majumdar U, Choudhury TZ, Manivannan S et al. Single-cell RNA-sequencing analysis of aortic valve interstitial cells demonstrates the regulation of integrin signaling by nitric oxide Frontiers in Cardiovascular Medicine 2022-10-25 [PMID: 36386365] (WB) |
WB |
|
| Reuter SP, Soonpaa MH, Field D et al. Cardiac Troponin I-interacting Kinase Impacts Cardiomyocyte S-phase Activity But Not Cardiomyocyte Proliferation Circulation 2022-11-16 [PMID: 36382596] |
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| Bachmann S, Bell M, Klimek J, Zempel H Subcellular localization of TAU isoforms and their influence on microtubule dynamics bioRxiv 2020-06-17 |
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| Griem-Krey N, Gauger SJ, Gowing EK et al. The CaMKIIa hub ligand Ph-HTBA promotes neuroprotection after focal ischemic stroke by a distinct molecular interaction Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022-10-20 [PMID: 36274464] (WB, Mouse) |
WB |
Mouse |
| Arias-Garcia M, Rickman R, Sero J The cell-cell adhesion protein JAM3 determines nuclear deformability by regulating microtubule organization biorxiv.org Jan 1 2019 (WB, Human) |
WB |
Human |
| Wang YC, Tsai MC, Chen YS et al. NPRL2 down-regulation facilitates the growth of hepatocellular carcinoma via the mTOR pathway and autophagy suppression Hepatology communications 2022-12-01 [PMID: 36321403] (WB, Human) |
WB |
Human |
| Gerwinn T, Salemi S, Schori LJ et al. Improved contractile potential in detrusor microtissues from pediatric patients with end stage lower urinary tract dysfunction Frontiers in Cell and Developmental Biology 2022-10-04 [PMID: 36268506] (ICC/IF) |
ICC/IF |
|
| Kansakar U, Gambardella J, Varzideh F et al. miR-142 Targets TIM-1 in Human Endothelial Cells: Potential Implications for Stroke, COVID-19, Zika, Ebola, Dengue, and Other Viral Infections International Journal of Molecular Sciences 2022-09-06 [PMID: 36142146] (WB) |
WB |
|
| Carew NT, Schmidt HM, Yuan S et al. Loss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death Journal of Clinical Investigation 2022-09-15 [PMID: 36106636] |
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Bousgouni V, Inge O, Robertson D et al. ARHGEF9 regulates melanoma morphogenesis in environments with diverse geometry and elasticity by promoting filopodial-driven adhesion iScience 2022-08-19 [PMID: 36039362] (WB, Human)
Details:
Dilution used 1:2000 |
WB |
Human |
| Ross BD, Jang Y, Welton A et al. A lymphatic-absorbed multi-targeted kinase inhibitor for myelofibrosis therapy Nature communications 2022-08-17 [PMID: 35977945] (WB, Mouse) |
WB |
Mouse |
Wavelet-Vermuse C, Odnokoz O, Xue Y et al. CDC20-Mediated hnRNPU Ubiquitination Regulates Chromatin Condensation and Anti-Cancer Drug Response Cancers 2022-07-31 [PMID: 35954396] (WB, Human)
Details:
Dilution used 1:1000 |
WB |
Human |
| Kubota S, Yamamoto Y, Kimura K A Chinese Medicine, Tokishakuyakusan, Increases Bovine Oviductal Tonus via G Protein-Coupled Estrogen Receptor 1 Biological & pharmaceutical bulletin 2022-07-31 [PMID: 35908895] (WB, Bovine) |
WB |
Bovine |
Ojeda-Juarez D, Lawrence J, Soldau K et al. Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus Neurobiology of disease 2022-07-26 [PMID: 35905927] (WB, Mouse)
Details:
Dilutions: 1:1000 |
WB |
Mouse |
| Huda N, Khambu B, Liu G et al. Senescence Connects Autophagy Deficiency to Inflammation and Tumor Progression in the Liver Cellular and molecular gastroenterology and hepatology 2022-04-08 [PMID: 35398596] (WB, Mouse) |
WB |
Mouse |
| Stephenson SEM, Costain G, Blok LER et al. Germline variants in tumor suppressor FBXW7 lead to impaired ubiquitination and a neurodevelopmental syndrome American journal of human genetics 2022-04-07 [PMID: 35395208] |
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| |
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| Jiao H, Wachsmuth L, Wolf S et al. ADAR1 averts fatal type I interferon induction by ZBP1 Nature 2022-07-01 [PMID: 35859176] (WB, Mouse) |
WB |
Mouse |
| Sugino Y, Sato T, Yamamoto Y, Kimura K. Evaluation of bovine uterine gland functions in 2D and 3D culture system Journal of Reproduction and Development 2022-08-01 [PMID: 35644574] (B/N, WB) |
B/N, WB |
|
| Kondylis V, Schneider F, Schorn F et al. p62 Promotes Survival and Hepatocarcinogenesis in Mice with Liver-Specific NEMO Ablation Cancers 2022-05-15 [PMID: 35626041] (WB, Mouse) |
WB |
Mouse |
| Mercado-Ay�n E, Warren N, Halawani S et al. Cerebellar Pathology in an Inducible Mouse Model of Friedreich Ataxia Frontiers in Neuroscience 2022-03-24 [PMID: 35401081] (WB, IHC) |
WB, IHC |
|
| Wen YC, Chen WY, Tram VTN et al. Pyruvate kinase L/R links metabolism dysfunction to neuroendocrine differentiation of prostate cancer by ZBTB10 deficiency Cell death & disease 2022-03-19 [PMID: 35306527] (Chemotaxis, Human) |
Chemotaxis |
Human |
| Fan CS, Chen CC, Chen LL et al. Extracellular HSP90 alpha Induces MyD88-IRAK Complex-Associated IKK alpha/beta NF-kappa B/IRF3 and JAK2/TYK2-STAT-3 Signaling in Macrophages for Tumor-Promoting M2-Polarization Cells 2022-01-11 [PMID: 35053345] (WB, Human) |
WB |
Human |
| Zhao W, Li X, Nian W et al. Ribosome Proteins Represented by RPL27A Mark the Development and Metastasis of Triple-Negative Breast Cancer in Mouse and Human Frontiers in Cell and Developmental Biology 2021-08-23 [PMID: 34497807] (WB, B/N) |
WB, B/N |
|
| Kadhim H Functional and Physiological Role of Extra-Hypothalamic Corticotropin Releasing Hormone Neurons in the Nucleus of the Hippocampal Commissure in Regulation of Stress Response Thesis Jan 1 2020 (WB) |
WB |
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| |
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| Crapser Jd Investigating microglial regulation of the extracellular matrix in health and neurodegenerative disease Award 2021-01-01 (WB) |
WB |
|
| Faucher-Giguere L, Roy A, Deschamps-Francoeur G et al. High-grade ovarian cancer associated H/ACA snoRNAs promote cancer cell proliferation and survival NAR cancer 2022-03-01 [PMID: 35047824] (WB, Human) |
WB |
Human |
| Bennett JS, Gordon DM, Majumdar U et al. Use of machine learning to classify high-risk variants of uncertain significance in lamin A/C cardiac disease Heart rhythm 2021-12-24 [PMID: 34958940] |
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| Weber RE, Schulze KM, Colburn TD et al. Capillary hemodynamics and contracting skeletal muscle oxygen pressures in male rats with heart failure: Impact of soluble guanylyl cyclase activator Nitric oxide : biology and chemistry 2021-12-04 [PMID: 34871799] (WB, Rat) |
WB |
Rat |
| Gerwinn T, Salemi S, Krattiger L Et al. Spheroids of Bladder Smooth Muscle Cells for Bladder Tissue Engineering BioMed research international 2021-11-11 [PMID: 34805410] (Simple Western, Rat) |
Simple Western |
Rat |
| Truong Quang BA, Peters R, Cassani DAD Et al. Extent of myosin penetration within the actin cortex regulates cell surface mechanics Nature communications 2021-11-11 [PMID: 34764258] (WB, Human) |
WB |
Human |
| Heath J, Cheyou ES, Findlay S Et al. POGZ promotes homology-directed DNA repair in an HP1-dependent manner EMBO reports 2021-11-10 [PMID: 34758190] |
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| Muzorewa TT, Buerk DG, Jaron D, Barbee KA Coordinated regulation of endothelial calcium signaling and shear stress-induced nitric oxide production by PKC beta and PKC eta. Cellular signalling 2021-08-30 [PMID: 34474112] (WB, Bovine) |
WB |
Bovine |
| Javeed N, Her TK, Brown MR Et al. Pro-inflammatory beta cell small extracellular vesicles induce beta cell failure through activation of the CXCL10/CXCR3 axis in diabetes Cell reports 2021-08-24 [PMID: 34433033] (WB, Mouse) |
WB |
Mouse |
| Lin HW, Lee JY, Chou NL Et al. Phosphorylation of PUF-A/PUM3 on Y259 modulates PUF-A stability and cell proliferation PloS one 2021-08-18 [PMID: 34407138] |
|
|
| Wang H, Chen J, Jandu S Et al. Probing tissue transglutaminase mediated vascular smooth muscle cell aging using a novel transamidation-deficient Tgm2-C277S mouse model Cell death discovery 2021-07-29 [PMID: 34326316] (WB) |
WB |
|
| Jo H, Park H, Choi Y et al. Portal Modulation Effects of Terlipressin on Liver Regeneration and Survival in a Porcine Model Subjected to 90% Hepatectomy Am J Transl Res 2021-07-26 [PMID: 34306332] |
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| Pan CH, Lin YP, Wang JY et al. Preventive Effect and Mechanism of Crossostephium chinense Extract on Balloon Angioplasty-Induced Neointimal Hyperplasia Evidence-based complementary and alternative medicine : eCAM 2021-06-30 [PMID: 34306155] (WB) |
WB |
|
| Behere A, Thornqvist Po, Winberg S Et Al. Visualization of early oligomeric alpha-synuclein pathology and its impact on the dopaminergic system in the (Thy-1)-h[A30P]alpha-syn transgenic mouse model Journal of neuroscience research 2021-07-22 [PMID: 34292621] (WB) |
WB |
|
| Zaganjor E, Yoon H, Spinelli JB et al. SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis Cell reports 2021-07-13 [PMID: 34260923] (WB) |
WB |
|
| Wang H, Poe A, Pak L Et Al. An in situ activity assay for lysyl oxidases Communications biology 2021-07-05 [PMID: 34226627] |
|
|
| Bachmann S, Bell M, Klimek J, Zempel H. Differential Effects of the Six Human TAU Isoforms: Somatic Retention of 2N-TAU and Increased Microtubule Number Induced by 4R-TAU Frontiers in Neuroscience 2021-05-25 [PMID: 34113229] (ICC/IF) |
ICC/IF |
|
| Hsieh Y, Lee K, Lei H et al. (Pro)renin Receptor Knockdown Attenuates Liver Fibrosis through Inactivation of ERK/TGF-beta1/SMAD3 Pathway Cellular and Molecular Gastroenterology and Hepatology 2021-06-01 [PMID: 34087453] |
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| Millan C, Prause L, Vallmajo-Martin Q et al. Extracellular Vesicles from 3D Engineered Microtissues Harbor Disease-Related Cargo Absent in EVs from 2D Cultures Advanced healthcare materials 2021-04-22 [PMID: 33890421] |
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| Guldiken N, Argemi J, Gurbuz B et al. Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases BMC medicine 2021-02-17 [PMID: 33593348] |
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| Ryder BD, Matlahov I, Bali S et al. Regulatory inter-domain interactions influence Hsp70 recruitment to the DnaJB8 chaperone Nature communications 2021-02-11 [PMID: 33574241] (WB, Human) |
WB |
Human |
| Majumdar U, Manivannan S, Basu M et al. Nitric oxide prevents aortic valve calcification by S-nitrosylation of USP9X to activate NOTCH signaling Science advances 2021-02-01 [PMID: 33547080] (WB, Human) |
WB |
Human |
| Liu T, Xing Y, Fan X et al. Fasting and overfeeding affect the expression of the immunity- or inflammation-related genes in the liver of poultry via endogenous retrovirus (ERV) Poult Sci 2021-02-01 [PMID: 33518151] |
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| Makino T, Izumi K, Hiratsuka K, et al. Anti-proliferative and anti-migratory properties of coffee diterpenes kahweol acetate and cafestol in human renal cancer cells Scientific reports 2021-01-12 [PMID: 33436830] (Human) |
|
Human |
| Fusco P, Mattiuzzo E, Frasson C et al. Verteporfin induces apoptosis and reduces the stem cell-like properties in Neuroblastoma tumour-initiating cells through inhibition of the YAP/TAZ pathway European journal of pharmacology 2020-12-18 [PMID: 33347823] (WB, Human) |
WB |
Human |
| Sanchez-Felipe, L, Vercruysse, T Et al. A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate. Nature 2020-12-01 [PMID: 33260195] (WB, Mouse) |
WB |
Mouse |
| Schlesinger S, Seo S, Pryce B et al. Loss of Smad4 in the scleraxis cell lineage results in postnatal joint contracture Dev Biol 2020-11-25 [PMID: 33248111] |
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Dermit M, Dodel M, Lee FCY et al. Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells Dev Cell 2020-11-09 [PMID: 33171110] (WB, Human)
Details:
Used as a control in Western blot along with HEK293T LARP6-knockout cells. |
WB |
Human |
| Pan C, Chen S, Wang J et al. Sclareol ameliorated ERCC1-mediated cisplatin resistance in A549 human lung adenocarcinoma cells and a murine xenograft tumor model by suppressing AKT-GSK3 beta-AP1/Snail and JNK-AP1 pathways Chemico-Biological Interactions 2020-10-01 [PMID: 33164868] (WB) |
WB |
|
| Yan S, Khambu B, Chen X et al. Hepatic autophagy deficiency remodels gut microbiota for an adaptive protection via FGF15-FGFR4 signaling Cell Mol Gastroenterol Hepatol 2020-10-22 [PMID: 33127558] (WB, Mouse) |
WB |
Mouse |
| Bahmad HF, Chalhoub RM, Harati H et al. Tideglusib attenuates growth of neuroblastoma cancer stem/progenitor cells in vitro and in vivo by specifically targeting GSK-3 beta Pharmacol Rep 2020-10-08 [PMID: 33030673] |
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| Macke A, Lopez W, Carlson DJ, Carlson KA Nora Virus VP4b and ORF1 Circulate in Hemolymph of Infected D. melanogaster with Coordinate Expression of Vago and Vir-1 Vaccines 2020-08-31 [PMID: 32878003] (WB, Drosophila) |
WB |
Drosophila |
| Chunchi Y, Zhao M, Li S Et Al. Increase of E3 ubiquitin-ligase NEDD4 expression leads to degradation of its target proteins PTEN/IGF1R during the formation of goose fatty liver J. Anim. Sci. 2020-08-25 [PMID: 32841331] |
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| Zhao S, Yuan C, Tuo X et al. MCLR induces dysregulation of calcium homeostasis and endoplasmic reticulum stress resulting in apoptosis in Sertoli cells Chemosphere 2020-08-15 [PMID: 32828052] |
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| Gordon SM, Nishiguchi MA, Mani S, Mainigi MA Interferons drive development of novel interleukin-15-responsive macrophages in the uterus J Immunol 2020-07-22 [PMID: 32690654] |
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| Potor L, Eva SK, Hegedus H et al. The Fungal Iron Chelator Desferricoprogen Inhibits Atherosclerotic Plaque Formation Int J Mol Sci 2020-07-03 [PMID: 32635347] (WB, Human) |
WB |
Human |
| Wang Y, Ji N, Gong X et al. Thioredoxin-1 attenuates atherosclerosis development through inhibiting NLRP3 inflammasome Endocrine 2020-06-30 [PMID: 32607763] (WB) |
WB |
|
| Xiong L, Zhao K, Cao Y et al. Linking skeletal muscle aging with osteoporosis by lamin A/C deficiency PLoS Biol. 2020-06-01 [PMID: 32479501] (WB, Mouse) |
WB |
Mouse |
| Chen KC, Chen CR, Chen CY et al. Bicalutamide Elicits Renal Damage by Causing Mitochondrial Dysfunction via ROS Damage and Upregulation of HIF-1 Int J Mol Sci 2020-05-11 [PMID: 32403414] (WB, Rat) |
WB |
Rat |
| Schwarzer R, Jiao H, Wachsmuth L et al. FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells Immunity 2020-04-22 [PMID: 32362323] |
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| Jiao H, Wachsmuth L, Kumari S et Al. Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation Nature 2020-03-25 [PMID: 32296175] (WB, Mouse) |
WB |
Mouse |
| Tu PS, Lin EC, Chen HW et al. The extracellular signal-regulated kinase 1/2 modulates the intracellular localization of DNA methyltransferase 3A to regulate erythrocytic differentiation Am J Transl Res 2020-03-15 [PMID: 32269731] (WB, Mouse, Human) |
WB |
Mouse, Human |
| Laurien L, Nagata M, SchUnke H et al. Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation Nat Commun 2020-04-08 [PMID: 32269263] (IP, Mouse) |
IP |
Mouse |
| Jannuzzi A, Arslan S, Yilmaz A et Al. Higher proteotoxic stress rather than mitochondrial damage is involved in higher neurotoxicity of bortezomib compared to carfilzomib Redox Biology 2020-01-01 [PMID: 32244176] (WB, PCR, Human) |
WB, PCR |
Human |
| Zavaczki E, Gall T, Zarjou A et Al. Ferryl Hemoglobin Inhibits Osteoclastic Differentiation of Macrophages in Hemorrhaged Atherosclerotic Plaques Oxid Med Cell Longev 2020-02-27 [PMID: 32184915] (WB, Mouse) |
WB |
Mouse |
| Morelli Ae, Sumpter Tl, Rojas-Canales Dm et Al. Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells Cell Rep 2020-03-10 [PMID: 32160549] (WB, Mouse) |
WB |
Mouse |
| Cipollari, E, Szapary, H J Et al. Correlates and Predictors of Cerebrospinal Fluid Cholesterol Efflux Capacity from Neural Cells, a Family of Biomarkers for Cholesterol Epidemiology in Alzheimer's Disease. J Alzheimers Dis 2020-02-18 [PMID: 32065798] (WB, Rat) |
WB |
Rat |
| Posta N, Csosz E, Oros M et al. Hemoglobin oxidation generates globin-derived peptides in atherosclerotic lesions and intraventricular hemorrhage of the brain, provoking endothelial dysfunction Lab. Invest. 2020-02-13 [PMID: 32054994] (WB, Human) |
WB |
Human |
| Davis DL, Mahawar U, Pope VS, Allegood J Dynamics of sphingolipids and the serine-palmitoyltransferase complex in oligodendrocytes during myelination. J Lipid Res 2020-02-12 [PMID: 32041816] |
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| Grolla AA, Miggiano R, Di Marino D et al. A nicotinamide phosphoribosyltransferase-GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus J. Biol. Chem. 2020-01-27 [PMID: 31988240] (WB, ICC/IF, Mouse, Human) |
WB, ICC/IF |
Mouse, Human |
| Kadomoto S, Izumi K, Hiratsuka K et al. Tumor-Associated Macrophages Induce Migration of Renal Cell Carcinoma Cells via Activation of the CCL20-CCR6 Axis Cancers (Basel) 2019-12-30 [PMID: 31905918] |
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| Zerfas B, Trader D Synthesis and Application of an Activity Based Peptide Peptoid Hybrid Probe for the Immunoproteasome Current Protocols in Chemical Biology 2019-12-01 [PMID: 31860787] (WB, Human) |
WB |
Human |
| Msheik H, El Hayek S, Bari MF, et al. Transcriptomic profiling of trophoblast fusion using BeWo and JEG-3 cell lines Mol. Hum. Reprod. 2019-12-01 [PMID: 31778538] (WB, Human) |
WB |
Human |
| Apaoblaza A, Gerrard SD, Matarneh SK et al. Muscle from grass- and grain-fed cattle differs energetically Meat Sci. 2019-11-06 [PMID: 31734468] (WB, Bovine) |
WB |
Bovine |
| Zhang H, Gong X, Ni S et al. C1q/TNF-related protein-9 attenuates atherosclerosis through AMPK-NLRP3 inflammasome singling pathway Int. Immunopharmacol. 2019-11-11 [PMID: 31727560] (WB, Mouse) |
WB |
Mouse |
| Choi H, Madhu V, Shapiro IM, Risbud MV Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation Sci Rep 2019-10-29 [PMID: 31664118] (WB, Human) |
WB |
Human |
| Wang Y, Cao J, Liu W et al. Protein tyrosine phosphatase receptor type R (PTPRR) antagonizes the Wnt signaling pathway in ovarian cancer by dephosphorylating and inactivating beta-catenin J. Biol. Chem. 2019-10-25 [PMID: 31653698] (WB, IP, Human) |
WB, IP |
Human |
| Fusco P, Parisatto B, Rampazzo E et al. Patient-derived organoids (PDOs) as a novel in vitro model for neuroblastoma tumours BMC Cancer 2019-10-21 [PMID: 31638925] (WB, Human) |
WB |
Human |
| Matthaeus C, Lian X et al. eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization. PLoS One 2019-11-10 [PMID: 31600286] (WB, Mouse) |
WB |
Mouse |
| Deora V, Lee JD, Albornoz EA et al. The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins Glia 2019-10-09 [PMID: 31596526] |
|
|
| Kovalchuke L, Mosharov EV, Levy OA, Greene LA Stress-induced phospho-ubiquitin formation causes parkin degradation Sci Rep 2019-08-12 [PMID: 31406131] (WB, Rat) |
WB |
Rat |
| Gunasekar P, Satish M, Dabestani P et al. Modulation of Cathepsin L Expression in the Coronary Arteries of Atherosclerotic Swine J Surg Res 2019-08-05 [PMID: 31377485] (WB, Porcine) |
WB |
Porcine |
| Crawley JTB, Zalli A, Monkman JH et al. Defective fibrin deposition and thrombus stability in Bambi-/- mice is mediated by elevated anticoagulant function J. Thromb. Haemost. 2019-07-27 [PMID: 31351019] (WB, Mouse) |
WB |
Mouse |
| Aggarwal M, Saxena R, Asif N et al. p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition J. Exp. Clin. Cancer Res. 2019-07-15 [PMID: 31307507] (IP, WB, Human, Mouse) |
IP, WB |
Human, Mouse |
| Penas C, Maloof ME, Stathias V et al. Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis Nat Commun 2019-07-10 [PMID: 31292434] (WB, Mouse) |
WB |
Mouse |
| Epp AL, Ebert SN, Sanchez-Arias JC et al. A novel motif in the proximal C-terminus of Pannexin 1 regulates cell surface localization Sci Rep 2019-07-05 [PMID: 31278290] (WB, Human) |
WB |
Human |
| Yan S, Zhou J, Chen X et al. Diverse Consequences in Liver Injury in Mice with Different Autophagy Functional Status Treated with Alcohol Am. J. Pathol. 2019-06-11 [PMID: 31199920] (Mouse) |
|
Mouse |
| Hans CP, Sharma N, Sen S et al. Transcriptomics Analysis Reveals New Insights into the Roles of Notch1 Signaling on Macrophage Polarization Sci Rep 2019-05-29 [PMID: 31142802] (WB, Mouse) |
WB |
Mouse |
| Kuo T, Damle M, Gonzalez BJ et al. Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle Cell Rep 2019-05-14 [PMID: 31091443] (Single Cell Western, Mouse) |
Single Cell Western |
Mouse |
| Polykratis A, Martens A, Eren RO et al. A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain Nat. Cell Biol. 2019-05-13 [PMID: 31086261] (WB, Mouse) |
WB |
Mouse |
| Sikura KE, Potor L, Szerafin T, Oros M et al. Hydrogen sulfide abrogates heart valve calcification: Implications for calcific aortic valve disease Br. J. Pharmacol. 2019-04-24 [PMID: 31017307] (WB, Human) |
WB |
Human |
| Zhou, C;Zeldin, Y;Baratz, ME;Kathju, S;Satish, L; Investigating the effects of Pirfenidone on TGF-Beta 1 stimulated non-SMAD signaling pathways in Dupuytren's disease -derived fibroblasts BMC Musculoskelet Disord 2019-03-30 [PMID: 30927912] (WB, Human) |
WB |
Human |
| Ren W, Hou J, Yang C et al. Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery J. Exp. Clin. Cancer Res. 2019-02-08 [PMID: 30736829] (WB, Human) |
WB |
Human |
| Wang CN, Lin YC, Chang BC et al. Targeting the phosphorylation site of MARCKS alleviates symptoms of steroid-resistant like asthma in a murine model Br. J. Pharmacol. 2019-02-01 [PMID: 30706455] (WB, Mouse) |
WB |
Mouse |
| Iwamoto H, Izumi K, Natsagdorj A et al. Coffee diterpenes kahweol acetate and cafestol synergistically inhibit the proliferation and migration of prostate cancer cells Prostate 2018-12-19 [PMID: 30569541] (WB, Human) |
WB |
Human |
| Natsagdorj A, Izumi K, Hiratsuka K et al. CCL2 induces resistance to the antiproliferative effect of cabazitaxel in prostate cancer cells. Cancer Sci. 2019-01-01 [PMID: 30426599] (WB, Human) |
WB |
Human |
| Qi M, Zhou Y, Liu J et al. AngII induces HepG2 cells to activate epithelial-mesenchymal transition. Exp Ther Med 2018-10-01 [PMID: 30233697] (WB, Human) |
WB |
Human |
| Huang F, Ben Aissa M, Levesque G, Carreau M. FANCC localizes with UNC5A at neurite outgrowth and promotes neuritogenesis. BMC Res Notes 2018-09-12 [PMID: 30213274] (WB, Mouse) |
WB |
Mouse |
| Tu W, Cheng C, Chen C et al. Annotation of differential protein expression in the hypothalami of layer-type Taiwan country chickens in response to acute heat stress Journal of Thermal Biology 2018-10-01 [PMID: 30196895] (WB, Chicken) |
WB |
Chicken |
| Rudman M. Bromodomain and Extraterminal Domain-Containing Protein Inhibition Decreases Inflammation after Spinal Cord Injury Exp Neurol 2018-08-23 [PMID: 30134146] |
|
|
| Tu WL, Cheng CY, Chen CJ et al. Proteomic analysis of the hypothalamus of broiler-type Taiwan country chickens in response to acute heat stress Anim. Sci. J. 2018-08-20 [PMID: 30125421] (WB, Chicken) |
WB |
Chicken |
| Iannotti FA, Pagano E, Moriello AS et al. Effects of non-euphoric plant cannabinoids on muscle quality and performance of dystrophic mdx mice Br. J. Pharmacol. 2018-08-03 [PMID: 30074247] (WB, Mouse) |
WB |
Mouse |
| Zhang H, Yan S, khambu B et al. Dynamic MTORC1-TFEB feedback signaling regulates hepatic autophagy, steatosis and liver injury in long-term nutrient oversupply. Autophagy. 2018-07-25 [PMID: 30044707] (WB, Mouse) |
WB |
Mouse |
| Ter-Avetisyan G, Dumoulin A, Herrel A et al. Loss of Axon Bifurcation in Mesencephalic Trigeminal Neurons Impairs the Maximal Biting Force in Npr2-Deficient Mice Front Cell Neurosci. [PMID: 29962937] (WB, Mouse) |
WB |
Mouse |
| Chen YH, Chen CJ, Wang SJ et al. Downregulation of tight junction protein zonula occludens-2 and urothelium damage in a cyclophosphamide-induced mouse model of cystitis. Taiwan J Obstet Gynecol 2018-06-01 [PMID: 29880173] |
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| Zhang Y, Chang JF, Sun J et al. Histone H3K27 methylation is required for NHEJ and genome stability by modulating the dynamics of FANCD2 on chromatin J. Cell. Sci. 2018-05-14 [PMID: 29760279] (WB, Human) |
WB |
Human |
| Davis S, Cirone A M et al. Phagocytosis-mediated M1 activation by chitin but not by chitosan. Am J Physiol Cell Physiol 2018-01-07 [PMID: 29719169] (WB, Mouse) |
WB |
Mouse |
| Choi H, Chaiyamongkol W, Doolittle AC et al. COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells. J Biol Chem 2018-06-08 [PMID: 29700115] (Mouse) |
|
Mouse |
| Chen L, Zhu G, Johns EM, Yang X. TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14. Nat Commun. 2018-03-26 [PMID: 29581427] (WB, Human) |
WB |
Human |
| Maolake A, Izumi K, Natsagdorj A et al. Tumor necrosis factor-alpha induces prostate cancer cell migration in lymphatic metastasis through CCR7 upregulation Cancer Sci. 2018-05-01 [PMID: 29575464] (WB, Human) |
WB |
Human |
| Potor L, Jeney V, Nagy P et al. Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction In Atherosclerotic Lesion. Oxidative Medicine and Cellular Longevity 1905-07-09 [PMID: 29560080] (WB, Human) |
WB |
Human |
| Troster P, Haseleu J, Petersen J, Drees O. The Absence of Sensory Axon Bifurcation Affects Nociception and Termination Fields of Afferents in the Spinal Cord. Front Mol Neurosci. 2018-02-08 [PMID: 29472841] (WB, Mouse) |
WB |
Mouse |
| Fan CS, Chen WS, Chen LL, Chen CC. Osteopontin-integrin engagement induces HIF-1a-TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer. Oncotarget. 2018-01-12 [PMID: 29435158] (WB, Human) |
WB |
Human |
| Langhorst H, Juttner R, Groneberg D et al. The IgCAM CLMP is required for intestinal and ureteral smooth muscle contraction by regulating Connexin43 and 45 expression in mice Dis Model Mech 2018-01-19 [PMID: 29361518] (Mouse) |
|
Mouse |
| Urata S, Izumi K, Hiratsuka K et al. C-C motif ligand 5 promotes migration of prostate cancer cells in the prostate cancer bone metastasis microenvironment. Cancer Sci. 2018-03-01 [PMID: 29288523] (WB, Human) |
WB |
Human |
| Fustaino V, Presutti D, Colombo T et al. Characterization of epithelial-mesenchymal transition intermediate/hybrid phenotypes associated to resistance to EGFR inhibitors in non-small cell lung cancer cell lines. Oncotarget 2017-11-28 [PMID: 29262566] (WB, Human) |
WB |
Human |
| Lin H, Magrane J, Clark EM et al. Early VGLUT1-specific parallel fiber synaptic deficits and dysregulated cerebellar circuit in the KIKO mouse model of Friedreich ataxia. Dis Model Mech 2017-12-19 [PMID: 29259026] (WB, Mouse) |
WB |
Mouse |
| Craighead D H, Wang H et al. Acute lysyl oxidase inhibition alters microvascular function in normotensive but not hypertensive men and women. Am J Physiol Heart Circ Physiol 2018-01-03 [PMID: 29167120] (WB, Human) |
WB |
Human |
| Nguyen TP, Yong HE, Chollangi T et al. Altered downstream target gene expression of the placental Vitamin D receptor in human idiopathic fetal growth restriction Cell Cycle. 2017-11-22 [PMID: 29161966] (WB, Human) |
WB |
Human |
| Liu C, Lee WC, Huang BM et al. 16-Hydroxycleroda-3, 13-dien-15, 16-olide inhibits the proliferation and induces mitochondrial-dependent apoptosis through Akt, mTOR, and MEK-ERK pathways in human renal carcinoma cells. Phytomedicine. 2017-10-03 [PMID: 29157834] (Human) |
|
Human |
| Lin H, Magrane J, Rattelle A et al. Early cerebellar deficits in mitochondrial biogenesis and respiratory chain complexes in the KIKO mouse model of Friedreich ataxia Dis Model Mech. 2017-11-01 [PMID: 29125827] (WB, Mouse) |
WB |
Mouse |
| Zeng Yen-Jing, Lin Yu-Hsiang, Wang You-Cheng et al. Laser acupuncture-induced analgesic effect and molecular alteRations in an incision pain model: a comparison with electroacupuncture-induced effects. Lasers in Medical Science 2018-01-01 [PMID: 29103083] (WB, Rat) |
WB |
Rat |
| Rostami J, Holmqvist S, Lindstrom V et al. Human astrocytes transfer aggregated alpha-synuclein via tunneling nanotubes J. Neurosci. 2017-10-31 [PMID: 29089438] (WB, Human) |
WB |
Human |
| Han J, Plummer J, Liu L et al. The impact of obesity on brain iron levels and a-synuclein expression is regionally dependent. Nutr Neurosci. 2017-10-16 [PMID: 29034829] (WB, Mouse) |
WB |
Mouse |
| Barone V, Lang M et al. An Effective Feedback Loop between Cell-Cell Contact Duration and Morphogen Signaling Determines Cell Fate. Dev Cell 2017-10-23 [PMID: 29033362] (WB, Zebrafish) |
WB |
Zebrafish |
| Lin X, Wang L, Wang F Chondromodulin-I suppresses tumorigenesis of human osteosarcoma cells Mol Med Rep 2017-01-01 [PMID: 28983591] (WB, Human) |
WB |
Human |
Sriwattanapong K, Slocum SL, Chawanthayatham S et al. Editor's Highlight: Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver. Toxicol. Sci. 2017-11-01 [PMID: 28973694] (WB, Mouse)
Details:
Novus GAPDH antibody clone 1D4 was used as a loading control for western blot to look at metabolic enzyme levels in pregnant vs nonpregnant mice |
WB |
Mouse |
| Liao HF, Pan CH, Chou PY et al. Toxicological effects of NCKU-21, a phenanthrene derivative, on cell growth and migration of A549 and CL1-5 human lung adenocarcinoma cells PLoS ONE 2017-09-25 [PMID: 28945763] (WB, Human) |
WB |
Human |
| Bove A, Gradeci D, Fujita Y et al. Local cellular neighbourhood controls proliferation in cell competition Mol. Biol. Cell 2017-09-20 [PMID: 28931601] (WB) |
WB |
|
| Gillen AE, Brechbuhl HM, Yamamoto TM et al. Alternative Polyadenylation of PRELID1 Regulates Mitochondrial ROS Signaling and Cancer Outcomes Mol. Cancer Res. 2017-09-14 [PMID: 28912168] (WB, Human) |
WB |
Human |
| Martin IV, Bohner A, Boor P et al. Complement C5a receptors C5L2 and C5aR in renal fibrosis Am. J. Physiol. Renal Physiol. 2017-09-13 [PMID: 28903945] (WB, Mouse) |
WB |
Mouse |
| Billon P, Bryant EE, Joseph SA et al. CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons. Mol. Cell 2017-09-21 [PMID: 28890334] (WB, Human) |
WB |
Human |
| Xu Q, Jitkaew S, Choksi S et al. The cytoplasmic nuclear receptor RARg controls RIP1 initiated cell death when cIAP activity is inhibited Nat Commun 2017-09-04 [PMID: 28871172] (WB, Mouse) |
WB |
Mouse |
| Lee A, Rayner SL, Gwee SSL et al. Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy. Cell Mol Life Sci 2018-01-01 [PMID: 28852778] (Human) |
|
Human |
| Vitte J, Gao F, Coppola G et al. Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development Nat Commun 2017-08-21 [PMID: 28824165] (WB, Mouse) |
WB |
Mouse |
| England E M, Shi H et al. Chronic activation of AMP-activated protein kinase increases monocarboxylate transporter 2 and 4 expression in skeletal muscle. J Anim Sci 2017-01-08 [PMID: 28805903] (WB, Porcine) |
WB |
Porcine |
| Zak TJ, Koshman YE, Samarel AM, Robia SL. Regulation of Focal Adhesion Kinase through a Direct Interaction with an Endogenous Inhibitor. Biochemistry 2017-08-23 [PMID: 28782937] |
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| George J, Tsutsumi M, Tsuchishima M. MMP-13 deletion decreases profibrogenic molecules and attenuates N-nitrosodimethylamine-induced liver injury and fibrosis in mice. J. Cell. Mol. Med. 2017-08-07 [PMID: 28782260] (WB, Mouse) |
WB |
Mouse |
| Sui Z, Gokhin DS, Nowak RB et al. Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells Mol. Biol. Cell 2017-07-18 [PMID: 28720661] (WB, Mouse) |
WB |
Mouse |
| Lin NH, Messing A, Perng MD. Characterization of a panel of monoclonal antibodies recognizing specific epitopes on GFAP PLoS ONE 2017-07-12 [PMID: 28700643] (WB, Human) |
WB |
Human |
| Wang Jialin, Djudjaj Sonja, Gibbert Lydia et al. YB-1 orchestrates onset and resolution of renal inflammation via IL10 gene regulation. J Cell Mol Med 2017-01-01 [PMID: 28664613] (WB, Mouse) |
WB |
Mouse |
| Sarowar T, Grabrucker S, Boeckers TM, Grabrucker, AM. Object Phobia and Altered RhoA Signaling in Amygdala of Mice Lacking RICH2. Front Mol Neurosci. 2017-06-23 [PMID: 28642683] (WB, Mouse) |
WB |
Mouse |
| Al-Ali H, Ding Y, Slepak T et al. The mTOR substrate S6 Kinase 1 (S6K1) is a negative regulator of axon regeneration and a potential drug target for Central Nervous System injury. J. Neurosci. 2017-06-16 [PMID: 28626016] (WB, Rat) |
WB |
Rat |
| Chugh P, Clark AG, Smith MB et al. Actin cortex architecture regulates cell surface tension. Nat. Cell Biol. 2017-05-22 [PMID: 28530659] |
|
|
| Almalki SG, Agrawal DK. ERK signaling is required for VEGF-A/VEGFR2-induced differentiation of porcine adipose-derived mesenchymal stem cells into endothelial cells. Stem Cell Res Ther 2017-05-12 [PMID: 28499402] (WB, Porcine) |
WB |
Porcine |
| Roux A, Loranger A, Lavoie JN, Marceau N. Keratin 8/18 regulation of insulin receptor signaling and trafficking in hepatocytes through a concerted phosphoinositide-dependent Akt and Rab5 modulation. FASEB J. 2017-04-25 [PMID: 28442548] (WB) |
WB |
|
| Chen HY, Chen CJ, Chen WC et al. A promising protein responsible for overactive bladder in ovariectomized mice. Taiwan J Obstet Gynecol. 2017-04-01 [PMID: 28420508] (WB, Mouse) |
WB |
Mouse |
| Ho TJ, Lee CW, Lu ZY et al. Effects of Electroacupuncture on Methamphetamine-Induced Behavioral Changes in Mice. Evid Based Complement Alternat Med 2017-03-16 [PMID: 28400844] (WB, Mouse) |
WB |
Mouse |
| Du M, Martin A, Hays F et al. Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4. Mol. Vis. 2017-04-12 [PMID: 28400700] (WB, Human) |
WB |
Human |
| Barr AR, Cooper S, Heldt FS et al. DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression. Nat Commun. 2017-03-20 [PMID: 28317845] (WB, Human) |
WB |
Human |
| Haick J M, Brueggemann L I et al. PKC-dependent regulation of Kv7.5 channels by the bronchoconstrictor histamine in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2017-01-06 [PMID: 28283479] (WB, Human) |
WB |
Human |
| Abou-Kheir W Barrak J Hadadeh O, Daoud G. HTR-8/SVneo cell line contains a mixed population of cells. Placenta. [PMID: 28161053] (WB, Human) |
WB |
Human |
| Hua Rong, Cheng Derrick, Coyaud Etienne et al. VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis. The Journal of Cell Biology 2017-01-20 [PMID: 28108526] |
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| Sero JE, Bakal C. Multiparametric Analysis of Cell Shape Demonstrates that b-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion Cell Syst 2017-01-25 [PMID: 28065575] (WB, Mouse) |
WB |
Mouse |
| Maolake A, Izumi K, Shigehara K et al. Tumor-associated macrophages promote prostate cancer migration through activation of the CCL22-CCR4 axis. Oncotarget. 2017-02-07 [PMID: 28039457] (WB, Human) |
WB |
Human |
| Sankowski R, Herring A, Keyvani K et al. The multi-target effects of CNI-1493: convergence of anti-amylodogenic and anti-inflammatory properties in animal models of Alzheimer's disease. Mol. Med. 2016-11-15 [PMID: 27847962] (WB, Mouse) |
WB |
Mouse |
| Lin J, Kumari S et al. RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Nature 2016-01-12 [PMID: 27819681] (WB, Mouse) |
WB |
Mouse |
| Yoon YM, Storm KJ, Kamimae-Lanning AN et al. Endogenous DNA Damage Leads to p53-Independent Deficits in Replicative Fitness in Fetal Murine Fancd2(-/-) Hematopoietic Stem and Progenitor Cells. Stem Cell Reports 2016-10-06 [PMID: 27720904] (WB, Mouse) |
WB |
Mouse |
| Palliyaguru DL, Chartoumpekis DV, Wakabayashi N et al. Withaferin A induces Nrf2-dependent protection against liver injury: role of Keap1-independent mechanisms Free Radic Biol Med. 2016-10-03 [PMID: 27717869] (WB, Mouse) |
WB |
Mouse |
| Willi M, Yoo KH, Wang C et al. Differential cytokine sensitivities of STAT5-dependent enhancers rely on Stat5 autoregulation. Nucleic Acids Res. 2016-09-30 [PMID: 27694626] (WB, Mouse) |
WB |
Mouse |
| Drelon C, Berthon A, Sahut-Barnola I et al. PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development Nat Commun 2016-09-14 [PMID: 27624192] (WB, Human) |
WB |
Human |
| Sandin L, Bergkvist L, Nath S et al. Beneficial effects of increased lysozyme levels in Alzheimer's disease modelled in Drosophila melanogaster. FEBS J. 2016-08-26 [PMID: 27562772] (WB) |
WB |
|
| Pelham CJ, Drews EM, Agrawal DK. Vitamin D controls resistance artery function through regulation of perivascular adipose tissue hypoxia and inflammation. J Mol Cell Cardiol 2016-09-01 [PMID: 27374117] (Mouse) |
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Mouse |
| Ochaba J, Monteys AM, O'Rourke JG et al. PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In Vivo. Neuron. 2016-05-04 [PMID: 27146268] (WB, Mouse) |
WB |
Mouse |
| Ding L, Paszkowski-Rogacz M, Winzi M et al. Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells. Cell Syst 2015-08-26 [PMID: 27135800] (ICC/IF) |
ICC/IF |
|
| Sun Chongxiu, Simon Scott I, Foster Greg A et al. 11,12-Epoxyecosatrienoic acids mitigate endothelial dysfunction associated with estrogen loss and aging: Role of membrane depolarization. Journal of Molecular and Cellular Cardiology 2016-01-01 [PMID: 27079253] (WB, Human) |
WB |
Human |
| Krapp C, Hotter D, Gawanbacht A et al. Guanylate Binding Protein (GBP) 5 Is an Interferon-Inducible Inhibitor of HIV-1 Infectivity. Cell Host Microbe. 2016-03-15 [PMID: 26996307] (WB, Human) |
WB |
Human |
| Karpel-Massler G, Banu M A et al. Inhibition of deubiquitinases primes glioblastoma cells to apoptosis in vitro and in vivo. Oncotarget 2016-03-15 [PMID: 26872380] (WB, Human) |
WB |
Human |
Kumper S, Mardakheh FK, McCarthy A et al. Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis. Elife. 2016-01-14 [PMID: 26765561] (WB, Mouse)
Details:
GAPDH antibody used as a loading control for WB on mouse embryo fibroblasts (MEFs) from embryos with different genotypes (Figure 1F). |
WB |
Mouse |
| Chen YC, Statt S, Wu R et al. High mobility group box 1-induced epithelial mesenchymal transition in human airway epithelial cells. Sci Rep. 2016-01-07 [PMID: 26739898] (WB, Human) |
WB |
Human |
| Slocum SL, Skoko JJ, Wakabayashi N et al. Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet. Arch. Biochem. Biophys. 2015-12-14 [PMID: 26701603] (WB, Mouse) |
WB |
Mouse |
| Brai E, Marathe S, Astori S et al. Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling. Front Cell Neurosci. 2015-12-04 [PMID: 26635527] (WB, Mouse) |
WB |
Mouse |
| Gokhin DS, Ochala J, Domenighetti AA, Fowler VM. Tropomodulin1 directly controls thin filament length in both wild-type and tropomodulin4-deficient skeletal muscle. Development. 2015-11-19 [PMID: 26586224] (WB, Mouse) |
WB |
Mouse |
| Presutti D, Santini S, Cardinali B et al. MET Gene Amplification and MET Receptor Activation Are Not Sufficient to Predict Efficacy of Combined MET and EGFR Inhibitors in EGFR TKI-Resistant NSCLC Cells. PLoS ONE. 2015-11-20 [PMID: 26580964] (WB, Human) |
WB |
Human |
| Becs G, Zarjou A, Agarwal A et al. Pharmacological induction of ferritin prevents osteoblastic transformation of smooth muscle cells. J Cell Mol Med 2016-02-01 [PMID: 26499096] |
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| DeLuca AP, Whitmore SS, Barnes J et al. Hypomorphic mutations in TRNT1 cause retinitis pigmentosa with erythrocytic microcytosis. Hum Mol Genet 2016-01-01 [PMID: 26494905] (WB) |
WB |
|
| Asghar A, Lajeunesse A, Dulla K et al. Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation. Nat Commun 2015-09-24 [PMID: 26399325] (WB) |
WB |
|
| Shang Y, Dong X, Han G et al. The Roles of Tight Junctions and Claudin-1 in the Microbubble-Mediated Ultrasound-Induced Enhancement of Drug Concentrations in Rat Prostate. J. Membr. Biol. 2015-08-20 [PMID: 26289600] (WB, Rat) |
WB |
Rat |
| Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signaling in the dorsal horn of the spinal cord. Khan N, Gordon R, Woodruff TM Pharmacol Res Perspect 2005-07-07 [PMID: 26171221] (WB, Mouse) |
WB |
Mouse |
| Ikhapoh IA, Pelham CJ, Agrawal DK. Atherogenic Cytokines Regulate VEGF-A-Induced Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells into Endothelial Cells. Stem Cells Int 2015-01-01 [PMID: 26106428] (WB) |
WB |
|
| Zakrzewicz A, Atanasova S, Padberg W. Monocytic Tissue Transglutaminase in a Rat Model for Reversible Acute Rejection and Chronic Renal Allograft Injury. Mediators of Inflammation. 2015-01-01 [PMID: 26063971] (WB, Rat) |
WB |
Rat |
Boosani CS, Dhar K, Agrawal DK. Down-regulation of hsa-miR-1264 contributes to DNMT1-mediated silencing of SOCS3. Mol. Biol. Rep. 2015-06-06 [PMID: 26047583] (WB, Human)
Details:
GAPDH antibody (clone 1D4) used for WB as a loading control on HCASMCs (human coronary artery smooth muscle) cells. Cells were transfected with hsa-miR-1264 mimic or its inhibitor and treated with or without TNF-alpha and IGF-1 (Fig. 3). |
WB |
Human |
| Serbo JV, Kuo S, Lewis S et al. Patterning of Fibroblast and Matrix Anisotropy within 3D Confinement is Driven by the Cytoskeleton Adv Healthc Mater. 2015-06-01 [PMID: 26033825] |
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| Chelluboina B, Warhekar A, Dillard M et al. Post-transcriptional inactivation of matrix metalloproteinase-12 after focal cerebral ischemia attenuates brain damage. Sci Rep. 2015-05-09 [PMID: 25955565] (WB, Rat) |
WB |
Rat |
| Baskar K, Sur S, Selvaraj V, Agrawal DK Functional constituents of a local serotonergic system, intrinsic to the human coronary artery smooth muscle cells. Mol Biol Rep 2015-08-01 [PMID: 25861735] (Human) |
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Human |
| Marathe S, Liu S, Brai E et al. Notch signaling in response to excitotoxicity induces neurodegeneration via erroneous cell cycle reentry Cell Death Differ. 2015-03-27 [PMID: 25822340] (IF/IHC, ICC/IF, Mouse) |
IF/IHC, ICC/IF |
Mouse |
| Aboelenain M, Kawahara M, Balboula AZ et al. Status of autophagy, lysosome activity and apoptosis during corpus luteum regression in cattle. J Reprod Dev 2015-06-20 [PMID: 25819401] (WB, Bovine) |
WB |
Bovine |
| Liu YN, Yin J, Barrett B et al. Loss of Androgen Regulated miR-1 Activates SRC and Promotes Prostate Cancer Bone Metastasis Mol. Cell. Biol. 2015-03-23 [PMID: 25802280] (Chemotaxis, WB, Mouse) |
Chemotaxis, WB |
Mouse |
| Zhou Q, Derti A, Ruddy DA et al. A chemical genetics approach for the functional assessment of novel cancer genes Cancer Res. 2015-03-18 [PMID: 25788694] (WB, Human) |
WB |
Human |
| Aubry S, Shin W, Crary JF et al. Assembly and Interrogation of Alzheimers Disease Genetic Networks Reveal Novel Regulators of Progression. PLoS One 2015-01-01 [PMID: 25781952] (WB, Human) |
WB |
Human |
| Bergert M, Erzberger A, Desai RA et al. Force transmission during adhesion-independent migration. Nat. Cell Biol. 2015-04-01 [PMID: 25774834] (WB, Human) |
WB |
Human |
| Zakrzewicz A, Kutlimuratov K, Atanasova S et al. Attenuation of Acute Rat Renal Allograft Rejection by Apolipoprotein E-Mimetic Peptide Transplantation 2015-02-25 [PMID: 25719257] (WB, Human) |
WB |
Human |
| De Boussac H, Maqdasy S, Trousson A et al. Enolase is regulated by Liver X Receptors Steroids. 2015-02-21 [PMID: 25708389] (WB, Mouse) |
WB |
Mouse |
| Kutz JL, Greaney JL, Santhanam L, Alexander LM. Evidence for a functional vasodilatory role for hydrogen sulfide in the human cutaneous microvasculature J. Physiol. (Lond.). 2015-01-30 [PMID: 25639684] (WB, Human, Rat) |
WB |
Human, Rat |
| Li J, Yuan W, Jiang S et al. Prolyl-4-hydroxylase Domain Protein 2 Controls NF-kB/p65 Transactivation and Enhances the Catabolic Effects of Inflammatory Cytokines on cells of the Nucleus Pulposus J. Biol. Chem. 2015-01-29 [PMID: 25635047] (WB, Human, Rat) |
WB |
Human, Rat |
| Izuagie IA, Pelham CJ, Agrawal DK. Synergistic effect of angiotensin II on vascular endothelial growth factor-A-mediated differentiation of bone marrow-derived mesenchymal stem cells into endothelial cells. Stem Cell Res Ther 2015-01-06 [PMID: 25563650] |
|
|
Ye W, Zhou J, Markova DZ et al. Xylosyltransferase-1 Expression Is Refractory to Inhibition by the Inflammatory Cytokines Tumor Necrosis Factor alpha and IL-1b in Nucleus Pulposus Cells: Novel Regulation by AP-1, Sp1, and Sp3. Am. J. Pathol. 2014-12-02 [PMID: 25476526] (WB, Human)
Details:
GAPDH antibody used for WB on lysates of human nucleus pulposus (NP) cells transduced with LV-shC or LV-shSp1 or LV-shSp3 (Figure 6) |
WB |
Human |
Liu Jt, Bain Lj. Arsenic inhibits hedgehog signaling during P19 cell differentiation. Toxicol. Appl. Pharmacol. 2014-12-15 [PMID: 25448440] (WB, Mouse)
Details:
GAPDH antibody used for WB at 1:1000 dilution on lysates of mouse embryonal carcinoma P19 cell line which was induced to differentiate for 5 days while being exposed to 0, 0.25, or 0.5 uM arsenic/ sodium arsenite (Fig 3A and 3C; Fig 6). |
WB |
Mouse |
| Chang Sh, Chang Wl, Lu Cc, Tarn Wy. Alanine repeats influence protein localization in splicing speckles and paraspeckles. Nucleic Acids Res. 2014-11-20 [PMID: 25414336] |
|
|
| Zhao N, Koenig Sn, Trask Aj et al. mir145 Regulates TGFBR2 Expression and Matrix Synthesis in Vascular Smooth Muscle Cells. Circ. Res. 2014-10-16 [PMID: 25323858] (WB, Mouse) |
WB |
Mouse |
| Peterson Jm, Mart R, Bond Ce. Effect of obesity and exercise on the expression of the novel myokines, Myonectin and Fibronectin type III domain containing 5. PeerJ. 2014-10-07 [PMID: 25289190] (WB, Rat) |
WB |
Rat |
Domingue JC, Ao M, Sarathy J et al. HEK-293 cells expressing the cystic fibrosis transmembrane conductance regulator (CFTR): a model for studying regulation of Cl- transport. Physiol Rep. 2014-09-01 [PMID: 25263207] (WB, Human)
Details:
MRP4 antibody used for WB at 1:750 dilution on cytosolic and total lysate fractions of HEK?CFTR cells as well as T84 cells (positive control). The antibody detected a band of 170 kDa size and the data is shown in Figure 5A - lower panel. |
WB |
Human |
| Chen X, Sadowska GB, Zhang et al. Neutralizing anti-interleukin-1b antibodies modulate fetal blood-brain barrier function after ischemia. Neurobiol. Dis. 2014-09-24 [PMID: 25258170] (WB, Sheep) |
WB |
Sheep |
Wang X, Wang H, Yang H et al. Tumor Necrosis Factor-a- and Interleukin-1b-Dependent Matrix Metalloproteinase-3 Expression in Nucleus Pulposus Cells Requires Cooperative Signaling via Syndecan 4 and Mitogen-Activated Protein Kinase-Nuclear Factor kB Axis: Implications in Inflammatory Disc Disease. Am. J. Pathol. 2014-07-22 [PMID: 25063530] (WB, Rat)
Details:
Glyceraldehyde-3-phosphate dehydrogenase / GAPDH antibody used for WB in TNF-alpha and IL-1 beta treated Rat's Nucleus pulposus/NP cells (Figure 1E, Figure 6A/E); TNF-alpha treated human NP cells transduced with either Sdc4-shRNA (LV-shSDC4) or Ctr-shRNA (LV-shC) (Figure 2C and E); human NP cells transduced with LV co-expressing YFP and either shp65 or shIkk beta (Figure 7C/E); TNF alpha/beta treated rat NP cells (Figure 8D). |
WB |
Rat |
Palsamy P, Bidasee KR, Shinohara T. Selenite cataracts: Activation of endoplasmic reticulum stress and loss of Nrf2/Keap1-dependent stress protection. Biochim. Biophys. Acta 2014-07-02 [PMID: 24997453] (WB, Human)
Details:
GAPDH antibody used for WB on lysates of human lens epithelial cells (HLECs) treated or not with 10 uM sodium selenite for various time periods (Fig 6, Fig 7, Fig 8, Fig 11). |
WB |
Human |
Alidousty C, Rauen T, Hanssen L et al. Calcineurin-mediated YB-1 dephosphorylation regulates CCL5 expression during monocyte differentiation. J. Biol. Chem. 2014-06-19 [PMID: 24947514] (WB, Rat, Mouse, Human)
Details:
Used in WB of GAPDH to ensure equal protein loading of whole cell lysates or cytoplasmatic extracts from Human primary monocytes, THP-1 cells, HEK293 cells, rat mesangial cells (rMCs) and kidney of C57BL/6 mice. |
WB |
Rat, Mouse, Human |
Holmes O, Paturi S, Selkoe DJ, Wolfe MS. Pen-2 Is Essential for gamma-Secretase Complex Stability and Trafficking but Partially Dispensable for Endoproteolysis Biochemistry. 2014-06-30 [PMID: 24941111] (WB, Mouse)
Details:
GAPDH antibody used as loading control in WB on lysates of Pen-2 knockout mouse embryonic fibroblasts/MEFs. Figure 6a - WB on stable cell lines of select Pen-2 mutants - monoclonal cell lines expressing wt, N8A, P27A, N33A, or I53A F-Pen-2; Figure 8 - WB on Pen-2 KO MEFs rescued with mutants of Pen-2 and treated with 8h - 10 uM MG132 ( a peptide aldehyde that effectively block the proteolytic activity of the 26S proteasome complex); Figure 10a - WB on Pen-2 KO MEFs treated with 10 uM MG132 or vehicle. |
WB |
Mouse |
McCord MC, Kullmann PH, He K et al. Syntaxin-binding domain of Kv2.1 is essential for the expression of apoptotic K+ currents. J. Physiol. (Lond.). 2014-06-13 [PMID: 24928958] (WB, Chinese Hamster)
Details:
Figure 3 C - Chinese hamster ovary (CHO) cells expressing syntaxin and Kv2.1 in the absence or presence of peptide C1a441–522 |
WB |
Chinese Hamster |
Chelluboina B, Klopfenstein JD, Pinson DM et al. Stem Cell Treatment After Cerebral Ischemia Regulates the Gene Expression of Apoptotic Molecules Neurochem. Res. 2014-05-31 [PMID: 24879430] (WB, Rat)
Details:
GAPDH antibody used as a loading control for WB on the brain tissues of male Sprague–Dawley rats - sham controls and untreated or hUCBSCs/human umbilical cord blood-derived mesenchymal stem cells - treated ischemic brains (experimental MCAO/middle cerebral artery occlusion model intravenously injected or not with hUCBSCs). WB image in Fig. 4 |
WB |
Rat |
| Bonachea Elizabeth M, Chang Sheng-Wei, Zender Gloria et al. Rare GATA5 sequence variants identified in individuals with bicuspid aortic valve. Pediatr Res. 2014-05-05 [PMID: 24796370] (Human) |
|
Human |
| Palsamy P, Bidasee KR, Ayaki M et al. Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts. Free Radic. Biol. Med. 2014-04-11 [PMID: 24746615] (WB, Human) |
WB |
Human |
| Wang SH, Cheng CY, Chen CJ et al. Changes in protein expression in testes of L2 strain Taiwan country chickens in response to acute heat stress. Theriogenology 2014-03-18 [PMID: 24725420] (WB, Chicken) |
WB |
Chicken |
| Steppan J, Sikka G, Jandu S et al. Exercise, vascular stiffness, and tissue transglutaminase. J Am Heart Assoc 2014-04-16 [PMID: 24721796] (WB, Rat, Mouse) |
WB |
Rat, Mouse |
| Kensler KH, Slocum SL, Chartoumpekis DV et al. Genetic or Pharmacologic Activation of Nrf2 Signaling Fails to Protect Against Aflatoxin Genotoxicity in Hypersensitive GSTA3 Knockout Mice. Toxicol. Sci. 2014-03-27 [PMID: 24675090] (WB, Mouse) |
WB |
Mouse |
Shah NH, Schulien AJ, Clemens K et al. Cyclin e1 regulates kv2.1 channel phosphorylation and localization in neuronal ischemia. J. Neurosci. 2014-03-19 [PMID: 24647953] (WB, Rat, Human)
Details:
This GAPDH antibody was used as a control in a Western Blot experiment to show an increase in neuronal cyclin E1 expression induced by chemical ischemia. |
WB |
Rat, Human |
| Gokhin DS, Tierney MT, Sui Z, Fowler VM. Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle. Mol. Biol. Cell 2014-01-15 [PMID: 24430868] (WB, Mouse) |
WB |
Mouse |
| Grabrucker S, Proepper C, Mangu, et al. The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation. Exp. Neurol. 2014-03-01 [PMID: 24382453] |
|
|
| Sun J, Liu SZ, Lin Y et al. TGF-beta promotes glioma cell growth via activating Nodal expression through Smad and ERK1/2 pathways. Biochem Biophys Res Commun 2013-12-25 [PMID: 24370825] (WB, Human) |
WB |
Human |
| Brosseau JP, Lucier JF, Nwilati H et al. Tumor microenvironment-associated modifications of alternative splicing. RNA 2014-02-01 [PMID: 24335142] (WB, Human) |
WB |
Human |
| Bohmer M, Sharbati J, Zur Bruegge J et al. Structural Analysis of microRNA-Target Interaction by Sequential Seed Mutagenesis and Stem-Loop 3' RACE. PLoS One. 2013-11-25 [PMID: 24282594] (WB, Human) |
WB |
Human |
| Lohmann D, Spandl J, Stevanovic A et al. Monoubiquitination of ancient ubiquitous protein 1 promotes lipid droplet clustering. PLoS One 2013-01-01 [PMID: 24039768] (Human) |
|
Human |
| Dickson JR, Kruse C, Montagna DR et al. Alternative polyadenylation and miR-34 family members regulate tau expression. J Neurochem. 2013-12-01 [PMID: 24032460] (WB, IP, Human) |
WB, IP |
Human |
| Premaraj S, Souza I, Premaraj T. Focal adhesion kinase mediates beta-catenin signaling in periodontal ligament cells. Biochem Biophys Res Commun. 2013-10-04 [PMID: 24021281] (WB, Human) |
WB |
Human |
| Jung SM, Jandu S, Steppan J et al. Increased tissue transglutaminase activity contributes to central vascular stiffness in eNOS knockout mice. Am J Physiol Heart Circ Physiol. 2013-09-01 [PMID: 23873798] (WB, Human) |
WB |
Human |
| Hanssen L, Alidousty C, Djudjaj S et al. YB-1 Is an Early and Central Mediator of Bacterial and Sterile Inflammation In Vivo. J Immunol 2013-07-19 [PMID: 23872051] (WB, Mouse) |
WB |
Mouse |
| Grotheer V, Goergens M, Fuchs PC et al. The performance of an orthosilicic acid-releasing silica gel fiber fleece in wound healing. Biomaterials. 2013-10-01 [PMID: 23830471] |
|
|
| Chelluboina B, Klopfenstein JD, Gujrati M et al. Temporal Regulation of Apoptotic and Anti-apoptotic Molecules After Middle Cerebral Artery Occlusion Followed by Reperfusion. Mol Neurobiol 2013-06-28 [PMID: 23813097] (WB, Rat) |
WB |
Rat |
| Rostami E, Davidsson J, Gyorgy A et al. The complement terminal pathway is activated in focal penetrating but not in mild diffuse Traumatic Brain Injury. J Neurotrauma 2013-06-28 [PMID: 23808389] (WB, Rat) |
WB |
Rat |
| Potor L, Banyai E, Becs G et al. Atherogenesis May Involve the Prooxidant and Proinflammatory Effects of Ferryl Hemoglobin. Oxid Med Cell Longev 2013-01-01 [PMID: 23766856] (WB, Human) |
WB |
Human |
| Kokubun K, Pankajakshan D, Kim MJ, Agrawal DK. Differentiation of porcine mesenchymal stem cells into epithelial cells as a potential therapeutic application to facilitate epithelial regeneration. J Tissue Eng Regen Med 2013-05-21 [PMID: 23696537] (Porcine) |
|
Porcine |
| Ishimoto T, Cara-Fuentes G, Wang H et al. Serum from minimal change patients in relapse increases CD80 expression in cultured podocytes. Pediatr Nephrol 2013-05-21 [PMID: 23689904] (WB, Human) |
WB |
Human |
| Tian Y, Yuan W, Fujita N et al. Inflammatory Cytokines Associated with Degenerative Disc Disease Control Aggrecanase-1 (ADAMTS-4) Expression in Nucleus Pulposus Cells through MAPK and NF-kB. Am J Pathol 2013-04-17 [PMID: 23602832] (WB, Rat) |
WB |
Rat |
| Wang H, Tian Y, Wang J et al. Inflammatory Cytokines Induce Notch Signaling in Nucleus Pulposus Cells: Implications in Intervertebral Disc Degeneration. J Biol Chem 2013-04-15 [PMID: 23589286] (Human) |
|
Human |
| Bosse K, Hans CP, Zhao N et al. Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease. J Mol Cell Cardiol 2013-04-10 [PMID: 23583836] (WB, Porcine) |
WB |
Porcine |
| Lyssenko NN, Nickel M, Tang C, Phillips MC. Factors controlling nascent high-density lipoprotein particle heterogeneity: ATP-binding cassette transporter A1 activity and cell lipid and apolipoprotein AI availability. FASEB J 2013-07-01 [PMID: 23543682] (Human) |
|
Human |
| Krishnamoorthy V, Donofrio AJ, Martin JL. O-GlcNAcylation of alphaB-crystallin regulates its stress-induced translocation and cytoprotection Mol Cell Biochem 2013-03-30 [PMID: 23543138] (WB, Rat) |
WB |
Rat |
Caldarelli A, Muller JP, Paskowski-Rogacz M et al. A genome-wide RNAi screen identifies proteins modulating aberrant FLT3-ITD signaling. Leukemia 2013-03-19 [PMID: 23508117] (WB, Human)
Details:
Using the PE conjugated version of NBP1-43352, catalog number NBP1-43352PE. |
WB |
Human |
| Dhar K, Rakesh K, Pankajakshan D, Agrawal DK. SOCS3 promotor hypermethylation and STAT3-NF-kappaB interaction downregulate SOCS3 expression in human coronary artery smooth muscle cells. Am J Physiol Heart Circ Physiol 2013-03-01 [PMID: 23335796] (WB, Human) |
WB |
Human |
| Jiang P, Du W, Mancuso A et al. Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence. Nature 2013-01-31 [PMID: 23334421] (WB, Human) |
WB |
Human |
| Youn H, Kim EJ, Um SJ. Zyxin cooperates with PTOV1 to confer retinoic acid resistance by repressing RAR activity. Cancer Lett 2013-01-12 [PMID: 23321499] (WB, Human) |
WB |
Human |
| Akundi RS, Zhi L, Sullivan PG, Bueler H. Shared and Cell Type-Specific Mitochondrial Defects and Metabolic Adaptations in Primary Cells from PINK1-Deficient Mice. Neurodegener Dis 2012-12-29 [PMID: 23295771] |
|
|
| Fang B, Guo HY, Zhang M et al. The Six-Amino Acid Antimicrobial Peptide bLFcin(6) Penetrates Cells and Delivers siRNA FEBS J 2012-12-14 [PMID: 23241223] (WB, Human) |
WB |
Human |
| Wang J, Tian Y, Phillips KL et al. Tumor necrosis factor alpha- and interleukin-1beta-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1. Arthritis Rheum 2013-03-01 [PMID: 23233369] (WB, Rat) |
WB |
Rat |
| Gokhin DS, Nowak RB, Kim NE et al. Tmod1 and CP49 Synergize to Control the Fiber Cell Geometry, Transparency, and Mechanical Stiffness of the Mouse Lens PLoS One 2012-01-01 [PMID: 23144950] (WB, Mouse) |
WB |
Mouse |
| Jing SW, Wang YD, Kuroda M et al. HIF-1 alpha Contributes to Hypoxia-induced Invasion and Metastasis of Esophageal Carcinoma via Inhibiting E-cadherin and Promoting MMP-2 Expression Acta Med Okayama 2012-10-01 [PMID: 23093058] (WB, Human) |
WB |
Human |
| Wang B, Sun J, Qian S et al. Proliferation and differentiation of osteoblastic cells on silicon-doped TiO2 film deposited by cathodic arc Biomed Pharmacother 2012-09-27 [PMID: 23089479] (WB, Human) |
WB |
Human |
| Farjo KM, Farjo RA, Halsey S et al. Retinol-binding protein 4 induces inflammation in human endothelial cells by an NADPH oxidase- and nuclear factor kappa B-dependent and retinol-independent mechanism Mol Cell Biol 2012-12-01 [PMID: 23071093] (WB, Human) |
WB |
Human |
| Peschard P, McCarthy A, Leblanc-Dominguez V et al. Genetic Deletion of RALA and RALB Small GTPases Reveals Redundant Functions in Development and Tumorigenesis Curr Biol 2012-10-09 [PMID: 23063435] (WB, Mouse) |
WB |
Mouse |
| Miao HL, Pan ZJ, Lei CJ et al. Knockdown of GPC3 inhibits the proliferation of Huh7 hepatocellular carcinoma cells through down-regulation of YAP. J Cell Biochem. 2013-03-01 [PMID: 23060277] (WB, Human) |
WB |
Human |
| Brambillasca S, Altkrueger A, Colombo SF et al. CDK5 Regulatory Subunit-associated Protein 1-Like 1 (CDKAL1) Is a Tail-anchored Protein in the Endoplasmic Reticulum (ER) of Insulinoma Cells. J Biol Chem 2012-12-07 [PMID: 23048041] (WB, Rat) |
WB |
Rat |
| Fang B, Jiang L, Zhang M, Ren FZ. A novel cell-penetrating peptide TAT-A1 delivers siRNA into tumor cells selectively Biochimie 2012-09-23 [PMID: 23009929] (WB, Human) |
WB |
Human |
| Chen X, Threlkeld SW, Cummings EE et al. Ischemia-reperfusion impairs blood-brain barrier function and alters tight junction protein expression in the ovine fetus. Neuroscience. 2012-01-01 [PMID: 22986172] (WB, Sheep) |
WB |
Sheep |
| Elanchezhian R, Palsamy P, Madson CJ et al. Age-related cataracts: Homocysteine coupled endoplasmic reticulum stress and suppression of Nrf2-dependent antioxidant protection Chem Biol Interact 2012-09-01 [PMID: 22964297] (WB, Human) |
WB |
Human |
| Roovers D Developing a reactivatable model for for HIV-1 Env expression mimicking latent infection Thesis 2022-01-01 |
|
|
| Bates RC, Stith BJ, Stevens KE. Chronic central administration of valproic acid: Increased pro-survival phospho-proteins and growth cone associated proteins with no behavioral pathology Pharmacol Biochem Behav 2012-08-31 [PMID: 22960225] (WB, Rat) |
WB |
Rat |
| Twigger K, Roulstone V, Kyula J et al. Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway BMC Cancer 2012-08-24 [PMID: 22920673] (WB, Human) |
WB |
Human |
| Cheng SP, Liu CL, Hsu YC et al. Expression and Biologic Significance of Adiponectin Receptors in Papillary Thyroid Carcinoma Cell Biochem Biophys 2012-08-21 [PMID: 22907586] (WB, Human) |
WB |
Human |
| Chu M, Koshman Y, Iyengar R et al. Contractile Activity Regulates Inducible Nitric Oxide Synthase Expression and NO(i) Production in Cardiomyocytes via a FAK-Dependent Signaling Pathway J Signal Transduct 2012-01-01 [PMID: 22900166] (WB, Rat) |
WB |
Rat |
| Tzeng BH, Chen YH, Huang CH et al. The Cav3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice Cardiovasc Res 2012-09-05 [PMID: 22886848] (WB, Rat) |
WB |
Rat |
| Djudjaj S, Chatziantoniou C, Raffetseder U et al. Notch-3 receptor activation drives inflammation and fibrosis following tubulointerstitial kidney injury J Pathol 2012-11-01 [PMID: 22806125] (WB, Rat) |
WB |
Rat |
| Pilar AV, Reid-Yu SA, Cooper CA et al. GogB is an anti-inflammatory effector that limits tissue damage during Salmonella infection through interaction with human FBXO22 and Skp1. PLoS Pathog 2012-01-01 [PMID: 22761574] (WB, Mouse) |
WB |
Mouse |
| Di YP, Zhao J, Harper R. Cigarette Smoke Induces MUC5AC Protein Expression through the Activation of Sp1 J Biol Chem 2012-08-10 [PMID: 22700966] (WB, Human) |
WB |
Human |
| Lange C, Brunswig-Spickenheier B, Eissing L, Scheja L. Platelet lysate suppresses the expression of lipocalin-type prostaglandin D2 synthase that positively controls adipogenic differentiation of human mesenchymal stromal cells Exp Cell Res 2012-06-11 [PMID: 22698646] (WB, Human) |
WB |
Human |
| Hong GM, Bain LJ. Arsenic exposure inhibits myogenesis and neurogenesis in P19 stem cells through repression of the B-catenin signaling pathway. Toxicol Sci. 2012-09-01 [PMID: 22641621] (WB, Mouse) |
WB |
Mouse |
| Elanchezhian R, Palsamy P, Madson CJ, Mulhern ML, Lynch DW, Troia AM, Usukura J, Shinohara T. Low glucose under hypoxic conditions induces unfolded protein response and produces reactive oxygen species in lens epithelial cells. Cell Death Dis;3. 2012-04-19 [PMID: 22513875] (WB, Human, Rat) |
WB |
Human, Rat |
| Lassance L, Miedl H, Konya V, Heinemann A, Ebner B, Hackl H, Desoye G, Hiden U. Differential response of arterial and venous endothelial cells to extracellular matrix is modulated by oxygen. Histochem Cell Biol. 2012-02-01 [PMID: 22294260] (WB, Human) |
WB |
Human |
| Hoeffer CA, Sanchez E, Hagerman RJ, Mu Y, Nguyen DV, Wong H, Whelan AM, Zukin RS, Klann E, Tassone F. Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome. Genes Brain Behav doi: 10.1111/j.1601-183X.2012.00768.x. 2012-01-23 [PMID: 22268788] (WB, Human) |
WB |
Human |
| Gokhin DS, Kim NE, Lewis SA et al. Thin filament length correlates with fiber type in human skeletal muscle. American Journal of Physiology. Cell Physiology. 2011-11-09 [PMID: 22075691] (WB, Human) |
WB |
Human |
| Veeravalli KK, Ponnala S, Chetty C et al. Integrin ?9[beta]1-mediated cell migration in glioblastoma via SSAT and Kir4.2 potassium channel pathway. Cellular Signalling. 2011-09-17 [PMID: 21946432] (WB, Mouse) |
WB |
Mouse |
| Akundi RS, Zhi L, Bueler H. PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis. Neurobiology of Disease. 2011-09-16 [PMID: 21945539] (WB, Mouse) |
WB |
Mouse |
| Lee JW, Liao PC, Young KC, Chang CL, Chen SS, Chang TT, Lai MD, Wang SW. Identification of hnRNPH1, NF45, and C14orf166 as novel host interacting partners of the mature hepatitis C virus core protein. J Proteome Res;10(10):4522-34. 2011-10-07 [PMID: 21823664] (WB, Human) |
WB |
Human |
| Boor P, Celec P et al. The peroxisome proliferator-activated receptor-alpha agonist, BAY PP1, attenuates renal fibrosis in rats. Kidney Int 2011-01-12 [PMID: 21814170] (WB, Mouse) |
WB |
Mouse |
| Nitzsche A, Paszkowski-Rogacz M, Matarese F et al. RAD21 Cooperates with Pluripotency Transcription Factors in the Maintenance of Embryonic Stem Cell Identity. PLoS ONE 201. [PMID: 21589869] (WB, Mouse) |
WB |
Mouse |
Jeyasuria P, Subedi K, Suresh A et al. Elevated levels of uterine anti-apoptotic signaling may activate NFKB and potentially confer resistance to caspase 3-mediated apoptotic cell death during pregnancy in mice. Biol Reprod. 2011-08-01 [PMID: 21566000] (WB, Mouse)
Details:
WB: ATF6 (IMG-273) & GAPDH (IMG-5019A-1). Nuclear fractions of mouse uterus, Fig 6. Note: ATF6 (IMG-273) was seen at ~36 kDa, Fig 6. |
WB |
Mouse |
| Lee C-W, Leu S-JJ, Tzeng R-Y et al. Latent membrane protein 1 of Epstein-Barr virus regulates death-associated protein kinase 1 in lymphoblastoid cell line. Virology. 2011-02-24 [PMID: 21353277] (WB, Human) |
WB |
Human |
Ritchey ER, Bongini RE, Code KA et al. The pattern of expression of guanine nucleotide-binding protein beta3 in the retina is conserved across vertebrate species. Neuroscience. 2010-09-01 [PMID: 20538044] (WB, IHC-Fr, Chicken)
Details:
GAPDH-Loading Control (IMG-5019A-1). WB & IHC (frozen): P7 wild type and RGE -/- chicken retina, Fig 1B & Fig 1C. |
WB, IHC-Fr |
Chicken |
| Cote MC, Lavoie JR, Houle F et al. Regulation of vascular endothelial growth factor-induced endothelial cell migration by LIM kinase 1-mediated phosphorylation of annexin 1. J Biol Chem. 2010-03-12 [PMID: 20061392] (WB, Human) |
WB |
Human |
Chui JJ, Li MW, Di Girolamo N et al. Iris pigment epithelial cells express a functional lipopolysaccharide receptor complex. Invest Ophthalmol Vis Sci. 2010-05-01 [PMID: 20019359] (WB, Human)
Details:
GAPDH (IMG-5019A-1): WB, human ocular pigment epithelial and normal aqueous cells, Fig 3. |
WB |
Human |
| a DW, Steinmetz AG, Kocinsky HS. NHE3 function and phosphorylation are regulated by a calyculin A-sensitive phosphatase. Am J Physiol Renal Physiol;298(3):F745-53. 2010-03-01 [PMID: 20015946] (WB, Primate, Opossum) |
WB |
Primate, Opossum |
| Holden P, Horton WA. Crude subcellular fractionation of cultured mammalian cell lines. BMC Res Notes 2009-12-10 [PMID: 20003239] (WB, Human) |
WB |
Human |
| Zhu ML, Kyprianou N. Role of androgens and the androgen receptor in epithelial-mesenchymal transition and invasion of prostate cancer cells. FASEB J. 2009-11-12 [PMID: 19901020] (WB, Human) |
WB |
Human |
| Kang YS, Zhao X, Lovaas J et al. Clathrin-independent internalization of normal cellular prion protein in neuroblastoma cells is associated with the Arf6 pathway. J Cell Sci;122(Pt 22):4062-9. 2009-11-15 [PMID: 19843586] (WB, Mouse) |
WB |
Mouse |
| Zhao J, Zhang Y, Ithychanda SS et al. Migfilin interacts with Src and contributes to cell-matrix adhesion-mediated survival signaling. J Biol Chem;284(49):34308-20. 2009-12-04 [PMID: 19833732] (ICC/IF, Human) |
ICC/IF |
Human |
| Kolosionek E, Savai R, Ghofrani HA et al. Expression and activity of phosphodiesterase isoforms during epithelial mesenchymal transition: the role of phosphodiesterase 4. Mol Biol Cell;20(22):4751-65. 2009-11-01 [PMID: 19759179] (WB, Human) |
WB |
Human |
| Fox JT, Shin WK, Caudill MA et al. A UV-responsive internal ribosome entry site enhances serine hydroxymethyltransferase 1 expression for DNA damage repair. J Biol Chem;284(45):31097-108. 2009-11-06 [PMID: 19734144] (WB, Human) |
WB |
Human |
| Fox JT, Stover PJ. Mechanism of the internal ribosome entry site-mediated translation of serine hydroxymethyltransferase 1. J Biol Chem;284(45):31085-96. 2009-11-06 [PMID: 19734143] (WB, Human) |
WB |
Human |
Chen H, Nguyen T, Shih Y et al. Combining microfluidic chip and low-attachment culture devices to isolate oral cancer stem cells Journal of Dental Sciences 2023-10-01 (WB, Human)
Details:
1:10000 dilution |
WB |
Human |
| Martin P, Liu YN, Pierce R et al. Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition. Am J Pathol 2011-07-01 [PMID: 21703421] (WB, Mouse) |
WB |
Mouse |
| Turner N, Abeysinghe P, Sadowski P, Mitchell M Cross-species proteomic and microRNA comparison of extracellular vesicles in human milk, cow�s milk, and infant formula products: moving towards next generation infant formula products bioRxiv 2023-02-24 (WB, Human, Bovine) |
WB |
Human, Bovine |
| Shima T, Mizokami A, Miyagi T et al. Down-regulation of calcium/calmodulin-dependent protein kinase kinase 2 by androgen deprivation induces castration-resistant prostate cancer Prostate 2012-12-01 [PMID: 22549914] (WB, Human) |
WB |
Human |
| Matta Benjamin M, Raimondi Giorgio, Rosborough Brian R et al. IL-27 production and STAT3-dependent upregulation of B7-H1 mediate immune regulatory functions of liver plasmacytoid dendritic cells. J Immunol 2012-01-01 [PMID: 22508931] (WB, Mouse) |
WB |
Mouse |
| Ahn J, Sanz-Moreno V, Marshall CJ. The metastasis gene NEDD9 product acts through integrin beta3 and Src to promote mesenchymal motility and inhibit amoeboid motility. J Cell Sci 2012-04-01 [PMID: 22328516] (Human) |
|
Human |
| Li M, Chen X, Ye QZ et al. A high-throughput FRET-based assay for determination of Atg4 activity. Autophagy 2012-03-01 [PMID: 22302004] (WB, Human) |
WB |
Human |
| Thomas AP, Dunn TN, Drayton JB et al. A high calcium diet containing nonfat dry milk reduces weight gain and associated adipose tissue inflammation in diet-induced obese mice when compared to high calcium alone Nutr Metab (Lond) 2012-01-23 [PMID: 22269778] (WB, Mouse) |
WB |
Mouse |
| Zhang K, Yuan K, Wu H, Li Q, Wang Y, Chen S, Zhang L, Gu H, Fu R. Identification of potential markers related to neoadjuvant chemotherapy sensitivity of breast cancer by SELDI-TOF MS. Appl Biochem Biotechnol;166(3):753-63. 2012-02-01 [PMID: 22127810] (WB, Human) |
WB |
Human |
| Wei Q, Hariharan V, Huang H. Cell-Cell Contact Preserves Cell Viability via Plakoglobin. PLoS ONE;6(10). 2011-01-01 [PMID: 22046445] (WB, Human) |
WB |
Human |
| Rosborough BR, Castellaneta A, Natarajan S et al. Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo J Leukoc Biol 2012-05-01 [PMID: 22028329] |
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| Fujiwara R, Chen S, Karin M, Tukey RH. Reduced expression of UGT1A1 in intestines of humanized UGT1 mice via inactivation of NF-?B leads to hyperbilirubinemia. Gastroenterology;142(1):109-118 e2. 2012-01-01 [PMID: 21983082] (WB, Mouse) |
WB |
Mouse |
| Tian X, Vroom C, Ghofrani H et al. Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodeling PLoS One 2011-04-11 [PMID: 21494592] (WB, Rat) |
WB |
Rat |
| Singaravelu K, Padanilam BJ. p53 target Siva regulates apoptosis in ischemic kidneys. Am J Physiol Renal Physiol;285(11):8013-21;300(5):F1130-41. 2011-05-01 [PMID: 21307125] (ICC/IF, Mouse) |
ICC/IF |
Mouse |
| Tiso M, Tejero J, Basu S et al. Human neuroglobin functions as a redox-regulated nitrite reductase. J Biol Chem 2011-05-20 [PMID: 21296891] (WB) |
WB |
|
| Elson-Schwab I, Lorentzen A, Marshall CJ. MicroRNA-200 family members differentially regulate morphological plasticity and mode of melanoma cell invasion. PLoS One 2010-01-01 [PMID: 20957176] (WB, Human) |
WB |
Human |
Swayne LA, Sorbara CD, Bennett SA. Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment. J Biol Chem. 2010-08-06 [PMID: 20529862] (WB)
Details:
WB: Neural stem and progenitor (NPC) cells isolated from postnatal day 3 C57BL/6 mouse hippocampus, Fig 1A. WB: Neuronal cells isolated from 14 day old C57BL/6 mouse neurospheres, Fig 2C & 3C. |
WB |
|
| Azman M Regulation of ribosome biogenesis by KRAS oncogene in Pancreatic Ductal Adenocarcinoma Thesis 2023-01-01 (WB, Mouse) |
WB |
Mouse |
| Lembo S, Strauss L, Cheng D et al. The distance between the plasma membrane and the actomyosin cortex acts as a nanogate to control cell surface mechanics bioRxiv 2023-02-01 (WB) |
WB |
|
| Costford SR, Bajpeyi S, Pasarica M et al. Skeletal muscle NAMPT is induced by exercise in humans. Am J Physiol Endocrinol Metab 2010-01-01 [PMID: 19887595] (WB, Human) |
WB |
Human |
| Villaseca S, Leal J, Guajardo J et al. G?i2-Mediated Regulation of Microtubules Dynamics and Rac1 Activity Orchestrates Cranial Neural Crest Cell Migration inXenopus bioRxiv 2023-09-08 (WB, Xenopus) |
WB |
Xenopus |
| Lin N, Vu Nguyen T, Shih Y et al. Association of higher transient receptor potential melastatin 8 expression with higher tumor histologic grades, lymph node metastasis, risk factors, and worse survival in patients with head and neck squamous cell carcinoma Journal of Dental Sciences 2023-09-22 |
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|
Hirai A, Ohtsuka N, Ikeda T et al. Role of mouse hepatitis virus (MHV) receptor murine CEACAM1 in the resistance of mice to MHV infection: studies of mice with chimeric mCEACAM1a and mCEACAM1b. J Virol. 2010-07-01 [PMID: 20410265] (WB, Mouse)
Details:
WB: The liver, spleen, and ileum of MHV-A59 infected mice, Fig 3A. |
WB |
Mouse |
| Jung YW, Kim YT, Kim SW et al. Correlation of human leukocyte antigen-G (HLA-G) expression and disease progression in epithelial ovarian cancer. Reprod Sci;16(11):1103-11. 2009-11-01 [PMID: 19692629] (WB, Human) |
WB |
Human |
| Kim JH, Bugaj LJ, Oh YJ et al. Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats. J Appl Physiol;107(4):1249-1257. 2009-01-01 [PMID: 19661445] (WB, Rat) |
WB |
Rat |
| Hynynen R, Suchanek M, Spl J et al. OSBP-related protein 2 is a sterol receptor on lipid droplets that regulates the metabolism of neutral lipids. J Lipid Res;50(7):1305-1315. 2009-01-01 [PMID: 19224871] (ICC/IF, Human) |
ICC/IF |
Human |
| Woodruff TM et al. The complement factor C5a contributes to pathology in a rat model of amyotrophic lateral sclerosis. J Immunol;181(12):8727-34. 2008-12-15 [PMID: 19050293] (WB, Rat) |
WB |
Rat |
| MacFarlane AJ et al. Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism. J Biol Chem;284(3):1533-9. 2009-01-16 [PMID: 19033438] (WB, Mouse) |
WB |
Mouse |
| Klein M, Schermuly RT, Ellinghaus P et al. Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling. Circulation;118(20):2081-90. 2008-11-11 [PMID: 18955668] (WB, Rat) |
WB |
Rat |
| Ezhilarasan Ravesanker, Jadhav Unmesh, Mohanam Indra et al. The hemopexin domain of MMP-9 inhibits angiogenesis and retards the growth of intracranial glioblastoma xenograft in nude mice. International Journal of Cancer 2009-01-01 [PMID: 18942717] (WB, Human) |
WB |
Human |
Singh A, Boldin-Adamsky S, Thimmulappa RK et al. RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy. Cancer Res. 2008-10-01 [PMID: 18829555] (WB, Human)
Details:
WB (human A549 and H460 cells), Fig. 1. |
WB |
Human |
| Wee S, Wiederschain D, Maira S-M et al. PTEN-deficient cancers depend on PIK3CB. Proc Natl Acad Sci U S A;105(35):13057-62. 2008-09-02 [PMID: 18755892] (WB, Human) |
WB |
Human |
| Smith HW, Marra P, Marshall CJ. uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180. J Cell Biol;182(4):777-90. 2008-08-25 [PMID: 18725541] (WB, Human) |
WB |
Human |
Alkam T, Nitta A, Mizoguchi H et al. The extensive nitration of neurofilament light chain in the hippocampus is associated with the cognitive impairment induced by amyloid beta in mice. J Pharmacol Exp Ther. 2008-10-01 [PMID: 18621989] (WB, Mouse)
Details:
WB (mouse hippocampal lysates), Fig. 7A. |
WB |
Mouse |
| Turnquist HR et al. IL-1beta-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells. J Immunol;181(1):62-72. 2008-07-01 [PMID: 18566370] (WB, Mouse) |
WB |
Mouse |
| Bove A. Single cell approaches to study the interaction between normal and transformed cells in epithelial monolayers. Thesis. 2018-01-01 (WB, Canine) |
WB |
Canine |
| Zhong L. microRNAs mediating E-selectin-dependent metastatic abilities of colon cancer cells and the signaling mechanisms behind their regulation. Thesis 1905-07-10 (WB, Human) |
WB |
Human |
| Catalgol B, Ziaja I, Breusing N et al. The Proteasome Is an Integral Part of Solar Ultraviolet A Radiation-induced Gene Expression. J Biol Chem;284(44):30076-30086. 2009-01-01 [PMID: 19690165] (WB, Human) |
WB |
Human |
| Matsui Y, Hadaschik BA, Fazli L et al. Intravesical combination treatment with antisense oligonucleotides targeting heat shock protein-27 HTI-286 as a novel strategy for high-grade bladder cancer. Mol Cancer Ther;8(8):2402-2411. 2009-01-01 [PMID: 19625496] (WB, Mouse) |
WB |
Mouse |
| Guerreiro JR, Lameu C, Oliveira EF et al. Argininosuccinate Synthetase Is a Functional Target for a Snake Venom Anti-hypertensive Peptide: ROLE IN ARGININE NITRIC OXIDE PRODUCTION. J Biol Chem;284(30):20022-20033. 2009-01-01 [PMID: 19491403] (WB, Human) |
WB |
Human |
| Sudarshan S, Sourbier C, Kong H-S et al. Fumarate Hydratase Deficiency in Renal Cancer Induces Glycolytic Addiction Hypoxia-Inducible Transcription Factor 1{alpha} Stabilization by Glucose-Dependent Generation of Reactive Oxygen Species. Mol Cell Biol;29(15):4080-4090. 2009-01-01 [PMID: 19470762] (WB, Human) |
WB |
Human |
| Ding L, Paszkowski-Rogacz M, Nitzsche A et al. A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. Cell Stem Cell 2009-05-08 [PMID: 19345177] (WB, Mouse) |
WB |
Mouse |
Kang Q, Wang T, Zhang H et al. A Golgi-associated protein 4.1B variant is required for assimilation of proteins in the membrane. J Cell Sci. 2009-04-15 [PMID: 19299464] (IP, Human)
Details:
IP (human bronchial epithelial cells), Fig. 7A. |
IP |
Human |
| Zhao J et al. Interleukin-13-induced MUC5AC is regulated by 15-lipoxygenase 1 pathway in human bronchial epithelial cells. Am J Respir Crit Care Med;179(9):782-90. 2009-05-01 [PMID: 19218191] (WB, Human) |
WB |
Human |
Dong C, Kwas C, Wu L. Transcriptional restriction of human immunodeficiency virus type 1 gene expression in undifferentiated primary monocytes. J Virol. 2009-04-01 [PMID: 19211771] (WB, Human)
Details:
WB (human monocytes), Figs. 5A,C; 7A. |
WB |
Human |
| Devalaraja-Narashimha K, Padanilam BJ. PARP-1 inhibits glycolysis in ischemic kidneys. J Am Soc Nephrol;20(1):95-103. 2009-01-01 [PMID: 19056868] (WB, Mouse) |
WB |
Mouse |
| Schmitt R, Marlier A, Cantley LG. Zag expression during aging suppresses proliferation after kidney injury. J Am Soc Nephrol;19(12):2375-83. 2008-12-01 [PMID: 18815245] (WB, Mouse) |
WB |
Mouse |
| Monteghirfo S et al. Antileukemia effects of xanthohumol in Bcr/Abl-transformed cells involve nuclear factor-kappaB and p53 modulation. Mol Cancer Ther;7(9):2692-702. 2008-09-01 [PMID: 18790751] (WB, Human) |
WB |
Human |
| Vene R et al. Glycogen synthase kinase 3beta regulates cell death induced by synthetic triterpenoids. Cancer Res;68(17):6987-96. 2008-09-01 [PMID: 18757413] (WB, Human) |
WB |
Human |
Macartney-Coxson DP, Hood KA, Shi HJ et al. Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level. BMC Cancer. 2008-07-01 [PMID: 18590575] (WB, Human)
Details:
GAPDH (IMG-5019A). WB: Human colon normal, colon tumour, and liver metastasis, Fig 5. |
WB |
Human |
| Chetty C, Lakka SS, Bhoopathi P et al. Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer. Cancer Res;68(12):4736-45. 2008-06-15 [PMID: 18559520] (WB, Human) |
WB |
Human |
| Bass-Zubek AE et al. Plakophilin 2: a critical scaffold for PKC alpha that regulates intercellular junction assembly. J Cell Biol;181(4):605-13. 2008-05-19 [PMID: 18474624] (WB, Human) |
WB |
Human |
| Diaz Encarnacion MM et al. Signaling pathways modulated by fish oil in salt-sensitive hypertension. Am J Physiol Renal Physiol;294(6):F1323-35. 2008-06-01 [PMID: 18385269] (WB, Rat) |
WB |
Rat |
| Zhang QS et al. Tempol protects against oxidative damage and delays epithelial tumor onset in Fanconi anemia mice. Cancer Res;68(5):1601-8. 2008-03-01 [PMID: 18316625] (WB, Mouse) |
WB |
Mouse |
Tsai WJ, McCormick KM, Brazeau DA et al. Estrogen effects on skeletal muscle insulin-like growth factor 1 and myostatin in ovariectomized rats. Exp Biol Med (Maywood). 2007-11-01 [PMID: 17959844] (WB, Rat)
Details:
WB (used as a gel loading control for rat muscle tissue lysates): Figs 6C, 7C, 8C. |
WB |
Rat |
| Limes, S W, P J Rozance et al. Increased insulin sensitivity and maintenance of glucose utilization rates in fetal sheep with placental insufficiency and intrauterine growth restriction. Am J Physiol Endocrinol Metab;293(6):E1716-25. 2007-12-01 [PMID: 17895285] (WB, Sheep) |
WB |
Sheep |
Banerjee PP, Pandey R, Zheng R et al. Cdc42-interacting protein-4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse. J Exp Med. 2007-10-01 [PMID: 17785506] (WB)
Details:
WB (Fig 8A): Protein standardization for siRNA studies. |
WB |
|
| Cui, W, E Cuartas et al. CD200 and its receptor, CD200R, modulate bone mass via the differentiation of osteoclasts. Proc Natl Acad Sci U S A;104(36):14436-41. 2007-09-04 [PMID: 17726108] (WB, Mouse) |
WB |
Mouse |
| Woeller CF, Fox JT, Perry C, Stover PJ. A ferritin-responsive internal ribosome entry site regulates folate metabolism. J Biol Chem;282(41):29927-35. 2007-10-12 [PMID: 17702748] (WB, Human) |
WB |
Human |
| Porchia, LM et al. 5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a celecoxib derivative, directly targets p21-activated kinase. Mol Pharmacol. 72(5):1124-31. Epub 2007 Aug 2. 2007-11-01 [PMID: 17673571] (WB, Human) |
WB |
Human |
Zhou M, Xia L, Wang J. Metformin transport by a newly cloned proton-stimulated organic cation transporter (plasma membrane monoamine transporter) expressed in human intestine. Drug Metab Dispos. 2007-10-01 [PMID: 17600084] (WB, Human)
Details:
Products cited for WB (human small intestine, Fig 6B): 1. GAPDH (IMG-5019A-1, -2) 2. INSTA-BLOT containing human small intenstine tissue lysate (IMB-103, IMB-123). |
WB |
Human |
Mao W, Fukuoka S, Iwai C et al. Cardiomyocyte apoptosis in autoimmune cardiomyopathy: mediated via endoplasmic reticulum stress and exaggerated by norepinephrine. Am J Physiol Heart Circ Physiol. 2007-09-01 [PMID: 17545481] (WB, Rabbit)
Details:
Antibodies cited: 1. ATF6 (IMG-273): WB (Fig 7), analysis of ATF6 in nuclear fraction of rabbit left ventricle myocardium tissue lysates, Authors describe cleaved forms of p90ATF6 in the nucleus: p60ATF6 and p36ATF6. 2. GAPDH (IMG-5019A): WB (Fig 4), GAPD |
WB |
Rabbit |
| Zhao N. Notch Signaling Guides Vascular Smooth Muscle Cell Function. Thesis. 2014-01-01 (WB, Human, Mouse) |
WB |
Human, Mouse |
| Chen, K, Y Tu et al. PINCH-1 regulates the ERK-Bim pathway and contributes to apoptosis resistance in cancer cells. J Biol Chem. 283(5):2508-17. 2008-02-01 [PMID: 18063582] (WB, Human) |
WB |
Human |
Blight KJ. Allelic variation in the hepatitis C virus NS4B protein dramatically influences RNA replication. J Virol. 2007-06-01 [PMID: 17360748] (WB, Human)
Details:
Antibodies cited: 1. GAPDH (IMG-5019A-1, IMG-5019A-2) [WB, Fig7, Fig8 (Huh-7.5 human hepatoma cell line)]. |
WB |
Human |
Redman PT, He K, Hartnett KA et al. Apoptotic surge of potassium currents is mediated by p38 phosphorylation of Kv2.1. Proc Natl Acad Sci USA 2007-02-27 [PMID: 17360683] (WB, Rat)
Details:
This GAPDH antibody was used as a loading control in a Western Blot experiment to show injury from oxidation increases S800 phosphorylation in cortical neurons. |
WB |
Rat |
| Block, K et al. NAD(P)H oxidases regulate HIF-2alpha protein expression. J Biol Chem;282(11):8019-26. 2007-03-16 [PMID: 17200123] (WB, Human) |
WB |
Human |
| Xia L, Engel K, Zhou M et al. Membrane localization and pH-dependent transport of a newly cloned organic cation transporter (PMAT) in kidney cells. Am J Physiol Renal Physiol. 2007-02-01 [PMID: 17018840] |
|
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| Wang G, Wu WW, Pisitkun T et al. Automated quantification tool for high-throughput proteomics using stable isotope labeling and LC-MSn. Anal Chem 2006-08-15 [PMID: 16906720] |
|
|
| Fatma, Sumbul et al. Research Articles: Pluronic L81 enhances triacylglycerol accumulation in the cytosol ingibits chylomicron secretion. 47: 2422-2432, 2006. [PMID: 16894241] (WB, Human) |
WB |
Human |
| Ju, J-S et al. Potentiation of insulin-stimulated glucose transport by the AMP-activated protein kinase. Am J Physiol Cell Physiol;292(1):C564-72. 2007-01-01 [PMID: 16870829] (WB, Mouse) |
WB |
Mouse |
| Kanadia, R N et al. Reversal of RNA missplicing and myotonia after muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy. Proc Natl Acad Sci U S A;103(31):11748-53. 2006-08-01 [PMID: 16864772] (WB, Mouse) |
WB |
Mouse |
| Iwatani M, Ikegami K, Kremenska Y et al. Dimethyl sulfoxide has an impact on epigenetic profile in mouse embryoid body. Stem Cells. 2006-11-01 [PMID: 16840553] |
|
|
| Shibata, Yoshimi et al. Heat-killed BCG induces biphasic cyclooxygenase 2+ splenic macrophage formation--role of IL-10 and bone marrow precursors. J Leukoc Biol;80(3):590-8. 2006-09-01 [PMID: 16822852] (WB, Mouse) |
WB |
Mouse |
| Le Boeuf F, Houle F, Sussman M et al. Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2-mediated phosphorylation of FAK on Tyr407 in response to vascular endothelial growth factor. Mol Biol Cell;17(8):3508-20. 2006-08-01 [PMID: 16760434] (WB, Human) |
WB |
Human |
| Barry, JS et al. Developmental changes in ovine myocardial glucose transporters and insulin signaling following hyperthermia-induced intrauterine fetal growth restriction. Exp Biol Med (Maywood);231(5):566-75. 2006-05-01 [PMID: 16636305] (WB, Sheep) |
WB |
Sheep |
| Azfer, A et al. Activation of endoplasmic reticulum stress response during the development of ischemic heart disease. Am J Physiol Heart Circ Physiol;291(3):H1411-20. 2006-09-01 [PMID: 16617122] (WB, Mouse) |
WB |
Mouse |
| Arthur DB et al. Inhibition of apoptosis by P2Y2 receptor activation: novel pathways for neuronal survival. J Neurosci;26(14):3798-804. 2006-04-05 [PMID: 16597733] (WB, Mouse) |
WB |
Mouse |
| Pisitkun, T et al. High-throughput identification of IMCD proteins using LC-MS/MS. Physiol Genomics;25(2):263-76. 2006-04-13 [PMID: 16449382] (WB, Rat) |
WB |
Rat |
| Jia, Y Takimoto, K Jia Y, Takimoto K. Mitogen-activated protein kinases control cardiac KChIP2 gene expression. Circ Res;98(3):386-93. 2006-02-17 [PMID: 16385079] (WB, Rat) |
WB |
Rat |
| Godsel, LM et al. Desmoplakin assembly dynamics in four dimensions: multiple phases differentially regulated by intermediate filaments and actin. J Cell Biol;171(6):1045-59. 2005-12-19 [PMID: 16365169] (WB, Human) |
WB |
Human |
| Dusek, R L et al. The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes. J Biol Chem;281(6):3614-24. 2006-02-10 [PMID: 16286477] (WB, Human) |
WB |
Human |
| Liu X, Kvetnansky R, Serova L et al. Increased susceptibility to transcriptional changes with novel stressor in adrenal medulla of rats exposed to prolonged cold stress. Brain Res Mol Brain Res. 2005-11-18 [PMID: 16169632] |
|
|
| Pendelton, LC et al. Regulation of endothelial argininosuccinate synthase expression and NO production by an upstream open reading frame. J Biol Chem;280(25):24252-60. 2005-06-24 [PMID: 15851478] (WB, Bovine) |
WB |
Bovine |
| Sarkar, S et al. Myocardial cell death and regeneration during progression of cardiac hypertrophy to heart failure. J Biol Chem;279(50):52630-42. 2004-12-10 [PMID: 15385543] (WB, Rat, Human) |
WB |
Rat, Human |
| Gonzales-Cabrera, P et al. Differential regulation of the cell cycle by alpha1-adrenergic receptor subtypes. Endocrinology;145(11):5157-67. 2004-11-01 [PMID: 15297446] (WB, Human, Rat) |
WB |
Human, Rat |
| Moshynska, O et al. Prognostic significance of a short sequence insertion in the MCL-1 promoter in chronic lymphocytic leukemia. J Natl Cancer Inst;96(9):673-82. 2004-05-05 [PMID: 15126604] (WB, Human) |
WB |
Human |
| Akassoglou, K et al. Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration. Proc Natl Acad Sci U S A;101(14):5075-80. 2004-04-06 [PMID: 15051870] (WB, IF/IHC, ICC/IF, Mouse) |
WB, IF/IHC, ICC/IF |
Mouse |
Ellis RC, Earnhardt JN, Hayes RL et al. Cathepsin B mRNA and protein expression following contusion spinal cord injury in rats. J Neurochem. 2004-02-01 [PMID: 14720218] (WB)
Details:
WB: GAPDH used as a protein loading control (rat spinal cord tissue), Fig. 3a,b,c. |
WB |
|
Fortun J, Dunn WA Jr, Joy S et al. Emerging role for autophagy in the removal of aggresomes in Schwann cells. J Neurosci. 2003-11-19 [PMID: 14627652] (WB, Mouse)
Details:
WB: GAPDH used as a protein loading control (Mouse Schwann cell lysates), Fig. 3F. |
WB |
Mouse |
| Kapadia SB, Brideau-Andersen A, Chisari FV et al. Interference of hepatitis C virus RNA replication by short interfering RNAs. Proc Natl Acad Sci U S A. 2003-02-01 [PMID: 12566571] (WB, ICC/IF, Human) |
WB, ICC/IF |
Human |
|
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-(025-ml)_NB300-221_11031.tif)
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![Analysis of cell line lysates probed with mouse mAb to GAPDH (theoretical molecular weight: 36 kDa), NB300-221, dilution 1:2,000: [1] protein standard, [2] HEK293, [3] HeLa, [4] SH-SY5Y, [5] COS1, [6] NIH-3T3, and [7] C6 cells. The GAPDH antibody reveals a single band at ~37 kDa in all cell lines. GAPDH is a house keeping protein, the level of which is relatively unaffected by most experimental manipulations, and, as a result, this antibody has been widely used as a western blotting loading control.](http://images.novusbio.com/fullsize/GAPDH-Antibody-1D4-Western-Blot-NB300-221-img0008.jpg "Analysis of cell line lysates probed with mouse mAb to GAPDH (theoretical molecular weight: 36 kDa), NB300-221, dilution 1:2,000: [1] protein standard, [2] HEK293, [3] HeLa, [4] SH-SY5Y, [5] COS1, [6] NIH-3T3, and [7] C6 cells. The GAPDH antibody reveals a single band at ~37 kDa in all cell lines. GAPDH is a house keeping protein, the level of which is relatively unaffected by most experimental manipulations, and, as a result, this antibody has been widely used as a western blotting loading control.")
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