TRAF-6 Antibody

The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using NBP1-80826	Applications	Species
Roy SC, Napit PR, Pasula MB et al. G-Protein-Coupled Lactate Receptor GPR81 Control of VMNvl Glucoregulatory Neurotransmitter and 5'-AMP-Activated Protein Kinase Expression American journal of physiology. Regulatory, integrative and comparative physiology 2022-11-21 [PMID: 36409024]
Mendiola Pla M, Milano CA, Chiang Y et al. Transvenous Endomyocardial Biopsy Technique for Intra-abdominal Heterotopic Cardiac Grafts Journal of cardiovascular translational research 2022-11-07 [PMID: 36344902]

Array NBP1-80826

• TRAF-6 Antibodies
• TRAF-6 Inhibitor
• TRAF-6 Lysates
• TRAF-6 Proteins