![Immunohistochemistry-Paraffin: TGF-beta Antibody (TGFB/7240) - Azide and BSA Free [NBP3-24126] - Formalin-fixed, paraffin-embedded human placenta stained with TGF-beta Antibody (TGFB/7240). Inset: PBS instead of primary antibody; secondary only negative control.](http://images.novusbio.com/fullsize/nbp3-24126_mouse-tgf-beta-mab-tgfb-7240-azide-and-bsa-free-24120257592877.jpg "Immunohistochemistry-Paraffin: TGF-beta Antibody (TGFB/7240) - Azide and BSA Free [NBP3-24126] - Formalin-fixed, paraffin-embedded human placenta stained with TGF-beta Antibody (TGFB/7240). Inset: PBS instead of primary antibody; secondary only negative control.")
| Reactivity | HuSpecies Glossary |
| Applications | IHC |
| Clone | TGFB/7240 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Unconjugated |
| Format | Azide and BSA Free |
| Concentration | 1 mg/ml |
| Description | Antibody without azide - store at -20 to -80C. |
| Immunogen | Recombinant fragment (around aa200-390) of human TGF-beta protein |
| Localization | Cytoplasm. Extracellular (secreted). |
| Specificity | This monoclonal antibody recognizes TGF beta 1, 2 and 3. |
| Isotype | IgG |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | TGFB1 |
| Purity | Protein A or G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Application Notes | Immunohistochemistry-Paraffin: 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined. |
| Storage | Store at -20 to -80C. Avoid freeze-thaw cycles. |
| Buffer | 10mM PBS |
| Preservative | No Preservative |
| Concentration | 1 mg/ml |
| Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for TGF-beta Antibody (NBP3-24126)Find related products by research area.
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Bad news for stomach cancer: BAMBI protein inhibits gastric carcinoma via TGF-beta/epithelial-mesenchymal transition signaling By Jamshed Arslan Pharm.D. Gastric carcinoma is the second leading cause of cancer-related deaths worldwide. One of the key features of gastric carcinoma is acidosis, which promotes growth and metastasis of gastric ... Read full blog post. |
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You complete me: Natural killer cells need TGF-beta inhibition to effectively combat cancers By Jamshed Arslan Pharm.D. Natural killer (NK) cells are lymphocytes of the innate immune system that were first discovered for their “natural” ability to kill cancer cells. To use NK cells as anti-cancer therapy, t... Read full blog post. |
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Stemness for Surviving Hypoxia: TGF-beta/Smad Signaling in Multiple Myeloma By Jamshed Arslan Pharm.D. Multiple myeloma (MM) is a cancer of antibody-producing plasma cells. The bone marrow (BM) of MM patients is hypoxic, and MM cells overexpress many cancerous genes that are regulated by hy... Read full blog post. |
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TGF-beta RIII - A multi-functional regulator of the TGF-beta signaling pathway Transforming growth factor-beta receptor III (TGF-beta RIII) is one of three receptors for the secreted growth factor TGF-beta. Unlike type I and type II TGF-beta receptors, TGF-beta RIII does not participate directly in the propagation of intracel... Read full blog post. |
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CCR2 or CD192 CCR2 is a receptor for several monocyte chemoattractant proteins (MCP1, MCP3, MCP4) that specifically govern monocyte chemotaxis. CCR2 transduces its downstream signals through increasing intracellular calcium ion levels. For example, MCP1 regulate... Read full blog post. |
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| Gene Symbol | TGFB1 |
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