I am looking for an ovine antibody for bFGF and PDGF-AB and ELISA Kits for both. It is for a research work on meniscus healing in sheep. Do you have anything suitable? How is the homology with sheep? Is it ever tested and/or published in papers?

Name: Recombinant Human FGF basic/FGF2/bFGF (146 aa) Protein
Brand: Novus Biologicals
SKU: 233-FB
Price: 237 USD

Unfortunately, most of the products you are interested in have not yet been tested in sheep, but this should not be a problem, due to sequence homology, and our Innovators Reward Program. In terms of an antibody for bFGF, also called FGF-2, we have several antibodies that are validated to detect the bovine protein, which is almost identical to that from sheep (99% homology). We only have FGF2 ELISA kits that have been tested with human or mouse. Mouse FGF-2 has 94% homology with sheep; human has 98% homology for most of its sequence, but also has an additional stretch of amino acids that is not present in the sheep protein. I therefore think that the mouse kit would be most suitable, just in case the human kit targets the region of the human protein not present in mouse. We sell antibodies to PDGF-A or PDGF-B rather than PDGF-AB. We don't have any PDGF-A antibodies that have been tested in sheep but there are several options you may find of interest. There isn't a sheep PDGFA sequence in UniProt, so I can't comment on how similar it is to the PDGFA from other species. Nevertheless, our NBP1-52533 PDGFB antibody has been shown to work in sheep. We sell two PDGF-AB ELISA kits , but these are for human and rat. I'm not sure how well these would work with sheep. Note that if you test a product with a species (or application) that it has not yet been validated in, you are eligible for our Innovator's Reward: Novus would provide you a 50% refund on the purchased product as well as a 50% discount on a future product of equal or lesser value. You would email innovators@novusbio.com to apply for your award, and we

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Recombinant Human FGF basic/FGF2/bFGF (146 aa) Protein

(528 Publications)

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Product Details

Summary

Reactivity	HuSpecies Glossary
Applications	Bioactivity

Order Details

View Available Formulations

Catalog# & Formulation	Size	Price
Carrier Free 233-FB-001MG/CF

Carrier Free 233-FB-025/CF

Carrier Free 233-FB-500/CF

Carrier Free 233-FB-010/CF

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Recombinant Human FGF basic/FGF2/bFGF (146 aa) Protein Summary

Details of Functionality	Measured in a cell proliferation assay using NR6R‑3T3 mouse fibroblast cells. Raines, E.W. et al. (1985) Methods Enzymol. 109:749. The ED₅₀ for this effect is 0.1-0.6 ng/mL.
Source	E. coli-derived human FGF basic/FGF2/bFGF protein Pro143-Ser288, with an N-terminal Ala
Accession #	P09038
N-terminal Sequence	Ala-Pro143
Protein/Peptide Type	Recombinant Proteins
Gene	FGF2
Purity	>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Note	<0.10 EU per 1 μg of the protein by the LAL method.

Applications/Dilutions

Dilutions

Bioactivity

Theoretical MW

16.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

SDS-PAGE

17 kDa, reducing conditions

Publications

Read Publications using
233-FB in the following applications:

Binding Assay
1 publication
Bioassay
466 publications
Cell Culture
38 publications
Differentiation
4 publications
Dififerentiation
1 publication
ELISA (Standard)
1 publication
In Vivo
10 publications
Tissue Culture
1 publication

Packaging, Storage & Formulations

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in Tris-HCl and NaCl with BSA as a carrier protein.
Purity	>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution Instructions	Reconstitute at 100-250 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Recombinant Human FGF basic/FGF2/bFGF (146 aa) Protein

basic fibroblast growth factor bFGF
Basic fibroblast growth factor
bFGF
FGF basic
FGF2
FGF-2
FGFBprostatropin
fibroblast growth factor 2 (basic)
HBGF-2
heparin-binding growth factor 2
Prostatropin

Background

FGF basic (also known as FGF-2 and HBGF-2) is a member of the FGF superfamily of mitogenic proteins which show 35-60% amino acid conservation. FGF acidic and basic are unique from other members of the family in that they lack classical secretory signal peptides. However, they are both readily secreted from cells by an alternative secretory pathway involving direct translocation and aided by several chaperones. FGF acidic (FGF-1) and FGF basic (FGF-2) were the first two identified FGFs, and the designations acidic and basic refer to their relative isoelectric points. The full length human FGF basic protein is 288 amino acids, but there are multiple start sites which produce various shorter forms. Further adding to the complexity, a variety of forms of FGF basic are produced as a result of N-terminal extensions. These extensions affect localization of FGF basic in cellular compartments but do not affect biological activity. FGF basic has been isolated from a number of sources, including neural tissue, adrenal cortex, pituitary gland, corpus luteum, and placenta. Binding of FGF to heparin or cell surface heparan sulfate proteoglycans is required for FGF binding with high affinity to FGF receptors. FGF basic stimulates proliferation of all cells of mesodermal origin as well as many cells of neuroectodermal, ectodermal, and endodermal origin. FGF basic also induces neuronal differentiation, survival, and regeneration, and modulates embryonic development and differentiation. These observed in vitro functions suggest FGF basic may play a role in vivo in the modulation of such normal processes as angiogenesis, wound healing and tissue repair, embryonic development and differentiation, and neuronal function and neural degeneration. Additionally, FGF basic may also participate in the development of several pathological conditions resulting from excessive cell proliferation and/or angiogenesis.

Coulier, F. et al. (1997) J. Mol. Evol. 44:43.
Chen, C.H. et al. (2004) Curr. Vasc. Pharmacol. 2:33.
Mohammadi, M. et al. (2005) Curr. Opin. Struct. Biol. 15:506.
Fernig, D. et al. (1994) Prog. Growth Factor Res. 5:353.

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Publications for FGF basic/FGF2/bFGF (233-FB)(528)

We have publications tested in 18 confirmed species: Human, Mouse, Rat, Bovine, Canine, Chick, Chicken, Hamster, Macaca fascicularis (cynomolgus monkey), Porcine, Primate, Primate - Callitrix jacchus (Common Marmoset), Primate - Chlorocebus pygerythrus (Vervet Monkey), Squirrel, Transgenic Mouse, Xenograft, Xenopus, Zebrafish.

We have publications tested in 8 applications: Binding Assay, Bioassay, Cell Culture, Differentiation, Dififerentiation, ELISA (Standard), In Vivo, Tissue Culture.

Showing Publications 1 - 10 of 528. Show All 528 Publications.

Publications using 233-FB	Applications	Species
Johnson, BB;Cosson, MV;Tsansizi, LI;Holmes, TL;Gilmore, T;Hampton, K;Song, OR;Vo, NTN;Nasir, A;Chabronova, A;Denning, C;Peffers, MJ;Merry, CLR;Whitelock, J;Troeberg, L;Rushworth, SA;Bernardo, AS;Smith, JGW; Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes Cell reports 2024-01-09 [PMID: 38198277] (Bioassay, Human)	Bioassay	Human
Fernando, MB;Fan, Y;Zhang, Y;Kammourh, S;Murphy, AN;Ghorbani, S;Onatzevitch, R;Pero, A;Padilla, C;Cao, L;Williams, S;Fang, G;Slesinger, PA;Brennand, KJ; Precise Therapeutic Targeting of Distinct NRXN1+/- Mutations bioRxiv : the preprint server for biology 2023-10-28 [PMID: 37961635] (Bioassay, Human)	Bioassay	Human
Friese-Hamim, M;Ortiz-Ruiz, MJ;Bogatyrova, O;Keil, M;Rohdich, F;Blume, B;Leuthner, B;Czauderna, F;Hahn, D;Jabs, J;Jaehrling, F;Heinrich, T;Kellner, R;Chan, K;Tong, AHY;Wienke, D;Moffat, J;Blaukat, A;Zenke, FT; Novel Methionine Aminopeptidase 2 Inhibitor M8891 Synergizes with VEGF Receptor Inhibitors to Inhibit Tumor Growth of Renal Cell Carcinoma Models Molecular cancer therapeutics 2023-11-08 [PMID: 37940144] (In Vivo, Transgenic Mouse)	In Vivo	Transgenic Mouse
Yang, Y;Yang, R;Kang, B;Qian, S;He, X;Zhang, X; Single-cell long-read sequencing in human cerebral organoids uncovers cell-type-specific and autism-associated exons Cell reports 2023-10-26 [PMID: 37889749] (Bioassay, Human)	Bioassay	Human
Lin, YW;Kao, HJ;Chen, WT;Kao, CF;Wu, JY;Chen, YT;Lee, YC; Cell-based screen identifies porphyrins as FGFR3 activity inhibitors with therapeutic potential for achondroplasia and cancer JCI insight 2023-10-12 [PMID: 37824212] (Bioassay, Mouse, Transgenic Mouse, Human)	Bioassay	Mouse, Transgenic Mouse, Human
Na, SB;Seo, BJ;Hong, TK;Oh, SY;Hong, YJ;Song, JH;Uhm, SJ;Hong, K;Do, JT; Altered Mitochondrial Function and Accelerated Aging Phenotype in Neural Stem Cells Derived from Dnm1l Knockout Embryonic Stem Cells International journal of molecular sciences 2023-09-19 [PMID: 37762596] (Bioassay, Mouse)	Bioassay	Mouse

Yang, X;Forró, C;Li, TL;Miura, Y;Zaluska, TJ;Tsai, CT;Kanton, S;McQueen, JP;Chen, X;Mollo, V;Santoro, F;Pa?ca, SP;Cui, B; Kirigami electronics for long-term electrophysiological recording of human neural organoids and assembloids bioRxiv : the preprint server for biology 2023-09-22 [PMID: 37790529] (Bioassay, Human)	Bioassay	Human
Gutierrez-Ruiz, OL;Johnson, KM;Krueger, EW;Nooren, RE;Cruz-Reyes, N;Heppelmann, CJ;Hogenson, TL;Fernandez-Zapico, ME;McNiven, MA;Razidlo, GL; Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion Cell reports 2023-08-30 [PMID: 37651233] (Human)		Human
Riesenberg, S;Kanis, P;Macak, D;Wollny, D;Düsterhöft, D;Kowalewski, J;Helmbrecht, N;Maricic, T;Pääbo, S; Efficient high-precision homology-directed repair-dependent genome editing by HDRobust Nature methods 2023-07-20 [PMID: 37474806] (Bioassay, Human)	Bioassay	Human
Voss, AJ;Lanjewar, SN;Sampson, MM;King, A;Hill, EJ;Sing, A;Sojka, C;Bhatia, TN;Spangle, JM;Sloan, SA; Identification of ligand-receptor pairs that drive human astrocyte development Nature neuroscience 2023-07-17 [PMID: 37460808] (Bioassay, Human)	Bioassay	Human
Alber, AB;Marquez, HA;Ma, L;Kwong, G;Thapa, BR;Villacorta-Martin, C;Lindstrom-Vautrin, J;Bawa, P;Wang, F;Luo, Y;Ikonomou, L;Shi, W;Kotton, DN; Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme Nature communications 2023-06-13 [PMID: 37311756] (Bioassay, Transgenic Mouse)	Bioassay	Transgenic Mouse
Martínez-Mármol, R;Giordano-Santini, R;Kaulich, E;Cho, AN;Przybyla, M;Riyadh, MA;Robinson, E;Chew, KY;Amor, R;Meunier, FA;Balistreri, G;Short, KR;Ke, YD;Ittner, LM;Hilliard, MA; SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity Science advances 2023-06-09 [PMID: 37285437] (Bioassay, Human)	Bioassay	Human
Han, L;Huang, D;Wu, S;Liu, S;Wang, C;Sheng, Y;Lu, X;Broxmeyer, HE;Wan, J;Yang, L; Lipid droplet-associated lncRNA LIPTER preserves cardiac lipid metabolism Nature cell biology 2023-06-01 [PMID: 37264180] (Bioassay, Human)	Bioassay	Human
Bates, EA;Lovatt, C;Plein, AR;Davies, JA;Siebzehnrubl, FA;Parker, AL; Engineering Adenoviral Vectors with Improved GBM Selectivity Viruses 2023-04-28 [PMID: 37243172] (Bioassay, Human)	Bioassay	Human
Hartmann, J;Henschel, N;Bartmann, K;D�nmez, A;Brockerhoff, G;Koch, K;Fritsche, E; Molecular and Functional Characterization of Different BrainSphere Models for Use in Neurotoxicity Testing on Microelectrode Arrays Cells 2023-04-27 [PMID: 37174670] (Bioassay, Human)	Bioassay	Human
Matkovic Leko, I;Schneider, RT;Thimraj, TA;Schrode, N;Beitler, D;Liu, HY;Beaumont, K;Chen, YW;Snoeck, HW; A distal lung organoid model to study interstitial lung disease, viral infection and human lung development Nature protocols 2023-05-10 [PMID: 37165073] (Bioassay, Human)	Bioassay	Human
Majd, H;Amin, S;Ghazizadeh, Z;Cesiulis, A;Arroyo, E;Lankford, K;Majd, A;Farahvashi, S;Chemel, AK;Okoye, M;Scantlen, MD;Tchieu, J;Calder, EL;Le Rouzic, V;Shibata, B;Arab, A;Goodarzi, H;Pasternak, G;Kocsis, JD;Chen, S;Studer, L;Fattahi, F; Deriving Schwann cells from hPSCs enables disease modeling and drug discovery for diabetic peripheral neuropathy Cell stem cell 2023-05-04 [PMID: 37146583] (Bioassay, Human)	Bioassay	Human
C Li, Z Yao, L Ma, X Song, W Wang, C Wan, S Ren, D Chen, Y Zheng, YT Zhu, G Chang, S Wu, K Miao, F Luo, XY Zhao Lovastatin promotes the self-renewal of murine and primate spermatogonial stem cells Stem Cell Reports, 2023-04-11;18(4):969-984. 2023-04-11 [PMID: 37044069] (Bioassay, Human)	Bioassay	Human
AA Almad, L Garcia, A Takanohash, A Gagne, W Yang, J Ann McGuir, D French, A Vanderver Generation of three induced Pluripotent Stem Cell lines from individuals with Hypomyelination with Atrophy of Basal Ganglia and Cerebellum caused by a c.745G>A (p.D249N) autosomal dominant mutation in TUBB4A Stem Cell Research, 2023-03-26;69(0):103083. 2023-03-26 [PMID: 37003180] (Bioassay, Human)	Bioassay	Human
Y Fan, J Hackland, A Baggiolini, LY Hung, H Zhao, P Zumbo, P Oberst, AP Minotti, E Hergenrede, S Najjar, Z Huang, NM Cruz, A Zhong, M Sidharta, T Zhou, E de Stanchi, D Betel, RM White, M Gershon, KG Margolis, L Studer hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease Cell Stem Cell, 2023-03-02;30(3):264-282.e9. 2023-03-02 [PMID: 36868194] (Bioassay, Human)	Bioassay	Human
Y Fan, J Hackland, A Baggiolini, LY Hung, H Zhao, P Zumbo, P Oberst, AP Minotti, E Hergenrede, S Najjar, Z Huang, NM Cruz, A Zhong, M Sidharta, T Zhou, E de Stanchi, D Betel, RM White, M Gershon, KG Margolis, L Studer hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease Cell Stem Cell, 2023;30(3):264-282.e9. 2023 [PMID: 36868194] (Bioassay, Human)	Bioassay	Human
NB Campbell, Y Patel, TL Moore, M Medalla, E Zeldich Extracellular Vesicle Treatment Alleviates Neurodevelopmental and Neurodegenerative Pathology in Cortical Spheroid Model of Down Syndrome International Journal of Molecular Sciences, 2023-02-09;24(4):. 2023-02-09 [PMID: 36834891] (Bioassay, Human)	Bioassay	Human
AR Dicks, GI Maksaev, Z Harissa, A Savadipour, R Tang, N Steward, W Liedtke, CG Nichols, CL Wu, F Guilak Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes Elife, 2023-02-22;12(0):. 2023-02-22 [PMID: 36810131] (Bioassay, Human)	Bioassay	Human
JM Gonzalez-M, S Ivins, CL Andoniadou, P Le Tissier, P Scambler, JP Martinez-B An expression and function analysis of the CXCR4/SDF-1 signalling axis during pituitary gland development PLoS ONE, 2023-02-17;18(2):e0280001. 2023-02-17 [PMID: 36800350] (Bioassay, Mouse)	Bioassay	Mouse
EF Cohn, BLL Clayton, M Madhavan, S Yacoub, Y Federov, K Paul-Fried, TJ Shafer, PJ Tesar Pervasive environmental chemicals impair oligodendrocyte development bioRxiv : the preprint server for biology, 2023-02-12;0(0):. 2023-02-12 [PMID: 36798415] (Bioassay, Human, Mouse)	Bioassay	Human, Mouse
L Pang, M Dunterman, W Xuan, A Gonzalez, Y Lin, WH Hsu, F Khan, RS Hagan, WA Muller, AB Heimberger, P Chen Circadian regulator CLOCK promotes tumor angiogenesis in glioblastoma Cell Reports, 2023-02-14;42(2):112127. 2023-02-14 [PMID: 36795563] (Bioassay, Human)	Bioassay	Human
RC Gimple, G Zhang, S Wang, T Huang, J Lee, S Taori, D Lv, D Dixit, ME Halbert, AR Morton, RL Kidwell, Z Dong, BC Prager, L Kim, Z Qiu, L Zhao, Q Xie, Q Wu, S Agnihotri, JN Rich Sorting-nexin-10 sustains platelet-derived growth factor receptor signaling in glioblastoma stem cells via endosomal protein sorting JCI Insight, 2023-03-22;0(0):. 2023-03-22 [PMID: 36795488] (Bioassay, Human)	Bioassay	Human
L Feige, T Kozaki, G Dias de Me, V Guillemot, F Larrous, F Ginhoux, H Bourhy Susceptibilities of CNS Cells towards Rabies Virus Infection Is Linked to Cellular Innate Immune Responses Viruses, 2022-12-29;15(1):. 2022-12-29 [PMID: 36680128] (Bioassay, Human)	Bioassay	Human
B Xu, H Shimauchi-, Y Yoshimoto, T Sadakata, Y Ishizaki Transplanted human iPSC-derived vascular endothelial cells promote functional recovery by recruitment of regulatory T cells to ischemic white matter in the brain Journal of Neuroinflammation, 2023-01-17;20(1):11. 2023-01-17 [PMID: 36650518] (Bioassay, Human)	Bioassay	Human
N Wang, J He, X Feng, S Liao, Y Zhao, F Tang, K Kee Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8 Elife, 2023-01-05;12(0):. 2023-01-05 [PMID: 36602025] (Bioassay, Human)	Bioassay	Human
M Chuai, G Serrano Ná, M Serra, L Mahadevan, CJ Weijer Reconstruction of distinct vertebrate gastrulation modes via modulation of key cell behaviors in the chick embryo Science Advances, 2023-01-04;9(1):eabn5429. 2023-01-04 [PMID: 36598979] (Bioassay, Chick)	Bioassay	Chick
SC Lin, YC Liao, PM Chen, YY Yang, YH Wang, SL Tung, CM Chuang, YW Sung, TH Jang, SE Chuang, LH Wang Periostin promotes ovarian cancer metastasis by enhancing M2 macrophages and cancer-associated fibroblasts via integrin-mediated NF-kappaB and TGF-beta2 signaling Journal of Biomedical Science, 2022-12-22;29(1):109. 2022-12-22 [PMID: 36550569] (Cell Culture, Human)	Cell Culture	Human
C Degorre, IC Sutton, SL Lehman, UT Shankavara, K Camphausen, PJ Tofilon Glioblastoma cells have increased capacity to repair radiation-induced DNA damage after migration to the olfactory bulb Cancer Cell International, 2022-12-08;22(1):389. 2022-12-08 [PMID: 36482431] (Cell Culture, Human)	Cell Culture	Human
JE Kaserman, RB Werder, F Wang, T Matte, MI Higgins, M Dodge, J Lindstrom-, P Bawa, A Hinds, E Bullitt, IS Caballero, X Shi, RE Gerszten, N Brunetti-P, M Liesa, C Villacorta, AN Hollenberg, DN Kotton, AA Wilson Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity Cell Reports, 2022-12-06;41(10):111775. 2022-12-06 [PMID: 36476855] (Bioassay, Human)	Bioassay	Human
AA Widjaja, S Viswanatha, SG Shekeran, E Adami, WW Lim, S Chothani, J Tan, JWT Goh, HM Chen, SY Lim, CM Boustany-K, J Hawkins, E Petretto, N Hübner, S Schafer, TM Coffman, SA Cook Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease Nature Communications, 2022-12-05;13(1):7497. 2022-12-05 [PMID: 36470928] (Bioassay, Human)	Bioassay	Human
HF Wu, W Yu, K Saito-Diaz, CW Huang, J Carey, F Lefcort, GW Hart, HX Liu, N Zeltner Norepinephrine transporter defects lead to sympathetic hyperactivity in Familial Dysautonomia models Nature Communications, 2022-11-17;13(1):7032. 2022-11-17 [PMID: 36396637] (Bioassay, Human)	Bioassay	Human
M Fujita, MM Chen, DR Siwak, S Sasagawa, A Oosawa-Tat, K Arihiro, A Ono, R Miura, K Maejima, H Aikata, M Ueno, S Hayami, H Yamaue, K Chayama, JS Lee, Y Lu, GB Mills, H Liang, SS Nishizuka, H Nakagawa Proteo-genomic characterization of virus-associated liver cancers reveals potential subtypes and therapeutic targets Nature Communications, 2022-10-29;13(1):6481. 2022-10-29 [PMID: 36309506] (Bioassay, Human)	Bioassay	Human
JH Song, J Choi, YJ Hong, H La, TK Hong, K Hong, JT Do Developmental Potency and Metabolic Traits of Extended Pluripotency Are Faithfully Transferred to Somatic Cells via Cell Fusion-Induced Reprogramming Cells, 2022-10-17;11(20):. 2022-10-17 [PMID: 36291134] (Bioassay, Human)	Bioassay	Human
AN Cho, F Bright, N Morey, C Au, LM Ittner, YD Ke Efficient Gene Expression in Human Stem Cell Derived-Cortical Organoids Using Adeno Associated Virus Cells, 2022-10-11;11(20):. 2022-10-11 [PMID: 36291062] (Bioassay, Human)	Bioassay	Human
VR Herrera Mi, B Canciani, L Mangiavini, JFS Filipe, L Aidos, M Pallaoro, GM Peretti, P Pocar, SC Modina, A Di Giancam Endostatin in 3D Fibrin Hydrogel Scaffolds Promotes Chondrogenic Differentiation in Swine Neonatal Meniscal Cells Biomedicines, 2022-09-27;10(10):. 2022-09-27 [PMID: 36289678] (Bioassay, Porcine)	Bioassay	Porcine
H Wang, B Keepers, Y Qian, Y Xie, M Colon, J Liu, L Qian Cross-lineage potential of Ascl1 uncovered by comparing diverse reprogramming regulatomes Cell Stem Cell, 2022-10-06;29(10):1491-1504.e9. 2022-10-06 [PMID: 36206732] (Bioassay, Mouse)	Bioassay	Mouse
P Dong, GE Hoffman, P Apontes, J Bendl, S Rahman, MB Fernando, B Zeng, JM Vicari, W Zhang, K Girdhar, KG Townsley, R Misir, CommonMind, KJ Brennand, V Haroutunia, G Voloudakis, JF Fullard, P Roussos Population-level variation in enhancer expression identifies disease mechanisms in the human brain Nature Genetics, 2022-09-26;54(10):1493-1503. 2022-09-26 [PMID: 36163279] (Bioassay, Human)	Bioassay	Human
D Yang, J Gomez-Garc, S Funakoshi, T Tran, I Fernandes, GD Bader, MA Laflamme, GM Keller Modeling human multi-lineage heart field development with pluripotent stem cells Cell Stem Cell, 2022-09-01;29(9):1382-1401.e8. 2022-09-01 [PMID: 36055193] (Bioassay, Human)	Bioassay	Human
Y Tang, DJ Kwiatkowsk, EP Henske Midkine expression by stem-like tumor cells drives persistence to mTOR inhibition and an immune-suppressive microenvironment Nature Communications, 2022-08-26;13(1):5018. 2022-08-26 [PMID: 36028490] (Bioassay, Mouse)	Bioassay	Mouse
S Martin, KC Allan, O Pinkard, T Sweet, PJ Tesar, J Coller Oligodendrocyte differentiation alters tRNA modifications and codon optimality-mediated mRNA decay Nature Communications, 2022-08-25;13(1):5003. 2022-08-25 [PMID: 36008413] (Bioassay, Mouse)	Bioassay	Mouse
K Kishimoto, K Iwasawa, A Sorel, C Ferran-Her, L Han, M Morimoto, JM Wells, T Takebe, AM Zorn Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems Nature Protocols, 2022-08-17;0(0):. 2022-08-17 [PMID: 35978039] (Cell Culture, Human)	Cell Culture	Human
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MK Samanta, S Gayen, C Harris, E Maclary, Y Murata-Nak, RM Malcore, RS Porter, PM Garay, CN Vallianato, PB Samollow, S Iwase, S Kalantry Activation of Xist by an evolutionarily conserved function of KDM5C demethylase Nature Communications, 2022-05-11;13(1):2602. 2022-05-11 [PMID: 35545632] (Bioassay, Mouse)	Bioassay	Mouse
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C Rodriguez-, N Kale, MJ Carlini, N Shrivastav, AA Rodrigues, B Khalil, JJ Bravo-Cord, M Alexander, J Ji, Y Hong, F Behbod, MS Sosa NR2F1 is a barrier to dissemination of early stage breast cancer cells Cancer Research, 2022-06-15;0(0):. 2022-06-15 [PMID: 35471456] (Cell Culture, Mouse)	Cell Culture	Mouse
Y Quan, M Wang, C Xu, X Wang, Y Wu, D Qin, Y Lin, X Lu, F Lu, L Li Cnot8 eliminates naï¿½ve regulation networks and is essential for naï¿½ve-to-formative pluripotency transition Nucleic Acids Research, 2022-05-06;0(0):. 2022-05-06 [PMID: 35390160] (Bioassay, Mouse)	Bioassay	Mouse
BK Gage, S Merlin, C Olgasi, A Follenzi, GM Keller Therapeutic correction of hemophilia A by transplantation of hPSC-derived liver sinusoidal endothelial cell progenitors Cell Reports, 2022-04-05;39(1):110621. 2022-04-05 [PMID: 35385743] (Bioassay, Human)	Bioassay	Human
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Y Shinmyo, K Saito, T Hamabe-Hor, N Kameya, A Ando, K Kawasaki, TAD Duong, M Sakashita, J Roboon, T Hattori, T Kannon, K Hosomichi, M Slezak, MG Holt, A Tajima, O Hori, H Kawasaki Localized astrogenesis regulates gyrification of the cerebral cortex Science Advances, 2022-03-11;8(10):eabi5209. 2022-03-11 [PMID: 35275722] (Bioassay, Mouse)	Bioassay	Mouse
J Chen, K Qiao, C Zhang, X Zhou, Q Du, Y Deng, L Cao VRK2 activates TNFalpha/NF-kappaB signaling by phosphorylating IKKbeta in pancreatic cancer International journal of biological sciences, 2022-01-09;18(3):1288-1302. 2022-01-09 [PMID: 35173553] (Bioassay, Human)	Bioassay	Human
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Z Pan, R Zhao, B Li, Y Qi, W Qiu, Q Guo, S Zhang, S Zhao, H Xu, M Li, Z Gao, Y Fan, J Xu, H Wang, S Wang, J Qiu, Q Wang, X Guo, L Deng, P Zhang, H Xue, G Li EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3 Molecular Cancer, 2022-01-14;21(1):16. 2022-01-14 [PMID: 35031058] (Bioassay, Human)	Bioassay	Human
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AF de Souza, FF Bressan, NCG Pieri, RC Botigelli, T Revay, SK Haddad, DT Covas, ES Ramos, WA King, FV Meirelles Generation of Primordial Germ Cell-like Cells from iPSCs Derived from Turner Syndrome Patients Cells, 2021-11-10;10(11):. 2021-11-10 [PMID: 34831322] (Bioassay, Human)	Bioassay	Human
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RS Kenchappa, Y Liu, MG Argenziano, MA Banu, AC Mladek, R West, A Luu, A Quiñones-H, D Hambardzum, V Justilien, M Leitges, JN Sarkaria, PA Sims, P Canoll, NR Murray, AP Fields, SS Rosenfeld Protein kinase C? and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities Cell Reports, 2021-11-23;37(8):110054. 2021-11-23 [PMID: 34818553] (Bioassay, Human)	Bioassay	Human
Y Gu, Y Chen, L Wei, S Wu, K Shen, C Liu, Y Dong, Y Zhao, Y Zhang, C Zhang, W Zheng, J He, Y Wang, Y Li, X Zhao, H Wang, J Tan, L Wang, Q Zhou, G Xie, H Liang, J Ou ABHD5 inhibits YAP-induced c-Met overexpression and colon cancer cell stemness via suppressing YAP methylation Nature Communications, 2021-11-18;12(1):6711. 2021-11-18 [PMID: 34795238] (Bioassay, Human)	Bioassay	Human
T Arad, N Fainstein, S Goldfarb, M Lachish, T Ganz, T Ben-Hur CD200 -dependent and -independent immune-modulatory functions of neural stem cells Stem Cell Research, 2021-10-07;56(0):102559. 2021-10-07 [PMID: 34634761] (Cell Culture, Mouse)	Cell Culture	Mouse
R Linares-Sa, W Kim, NA Bolar, H Zhang, BA Koch-Bojal, S Yoon, PP Shah, A Karnay, DS Park, JM Luppino, SC Nguyen, A Padmanabha, CL Smith, A Poleshko, Q Wang, L Li, D Srivastava, G Vahedi, GH Eom, GA Blobel, EF Joyce, R Jain BRD4 orchestrates genome folding to promote neural crest differentiation Nature Genetics, 2021-10-05;53(10):1480-1492. 2021-10-05 [PMID: 34611363] (Bioassay, Human)	Bioassay	Human
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Q Heydt, C Xintaropou, A Clear, M Austin, I Pislariu, F Miraki-Mou, P Cutillas, K Korfi, M Calaminici, W Cawthorn, K Suchacki, A Nagano, JG Gribben, M Smith, JD Cavenagh, H Oakervee, A Castleton, D Taussig, B Peck, A Wilczynska, L McNaughton, D Bonnet, F Mardakheh, B Patel Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence Nature Communications, 2021-09-17;12(1):5507. 2021-09-17 [PMID: 34535653] (Cell Culture, Human)	Cell Culture	Human
F Vujovic, S Rezaei-Lot, N Hunter, RM Farahani The fate of notch-1 transcript is linked to cell cycle dynamics by activity of a natural antisense transcript Nucleic Acids Research, 2021-10-11;0(0):. 2021-10-11 [PMID: 34520549] (Bioassay, Human)	Bioassay	Human
Y Aghazadeh, F Poon, F Sarangi, FTM Wong, ST Khan, X Sun, R Hatkar, BJ Cox, SS Nunes, MC Nostro Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models Cell Stem Cell, 2021-09-03;0(0):. 2021-09-03 [PMID: 34480863] (Bioassay, Human)	Bioassay	Human
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T Jia, T Jacquet, F Dalonneau, P Coudert, E Vaganay, C Exbrayat-H, J Vollaire, V Josserand, F Ruggiero, JL Coll, B Eymin FGF-2 promotes angiogenesis through a SRSF1/SRSF3/SRPK1-dependent axis that controls VEGFR1 splicing in endothelial cells Bmc Biology, 2021-08-25;19(1):173. 2021-08-25 [PMID: 34433435] (Bioassay, Human)	Bioassay	Human
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N Shimamura, K Fujii, S Ohkoshi Detection and quantification of human-specific mRNA from hepatocyte-like cells derived from dental pulp using real-time polymerase chain reaction Journal of oral biosciences, 2021-07-24;0(0):. 2021-07-24 [PMID: 34311038] (Bioassay, Human)	Bioassay	Human
SM Dieter, C Siegl, PL Codó, M Huerta, AL Ostermann-, E Schulz, MK Zowada, S Martin, K Laaber, A Nowrouzi, M Blatter, S Kreth, F Westermann, A Benner, U Uhrig, K Putzker, J Lewis, A Haegebarth, D Mumberg, SJ Holton, J Weiske, LM Toepper, U Scheib, G Siemeister, CR Ball, B Kuster, G Stoehr, H Hahne, S Johannes, M Lange, F Herbst, H Glimm Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer Cell Reports, 2021-07-20;36(3):109394. 2021-07-20 [PMID: 34289372] (Bioassay, Human)	Bioassay	Human
D Boso, E Carraro, E Maghin, S Todros, A Dedja, M Giomo, N Elvassore, P De Coppi, PG Pavan, M Piccoli Porcine Decellularized Diaphragm Hydrogel: A New Option for Skeletal Muscle Malformations Biomedicines, 2021-06-22;9(7):. 2021-06-22 [PMID: 34206569] (Bioassay, Human)	Bioassay	Human
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R Bhattachar, SE Black, MS Lotlikar, RH Fenn, M Jorfi, DM Kovacs, RE Tanzi Axonal generation of amyloid-&beta from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes Cell Reports, 2021-05-18;35(7):109134. 2021-05-18 [PMID: 34010653] (Bioassay, Human)	Bioassay	Human
C Wang, Y Li, L Jia, JK Kim, J Li, P Deng, W Zhang, PH Krebsbach, CY Wang CD276 expression enables squamous cell carcinoma stem cells to evade immune surveillance Cell Stem Cell, 2021-05-03;0(0):. 2021-05-03 [PMID: 33945793] (Bioassay, Human)	Bioassay	Human
A Abdullah, C Herdenberg, H Hedman Netrin-1 functions as a suppressor of bone morphogenetic protein (BMP) signaling Scientific Reports, 2021-04-21;11(1):8585. 2021-04-21 [PMID: 33883596] (Bioassay, Human)	Bioassay	Human
T Distler, I Lauria, R Detsch, CM Sauter, F Bendt, J Kapr, S Rütten, AR Boccaccini, E Fritsche Neuronal Differentiation from Induced Pluripotent Stem Cell-Derived Neurospheres by the Application of Oxidized Alginate-Gelatin-Laminin Hydrogels Biomedicines, 2021-03-05;9(3):. 2021-03-05 [PMID: 33808044] (Bioassay, Human)	Bioassay	Human
RM Agoglia, D Sun, F Birey, SJ Yoon, Y Miura, K Sabatini, SP Pa?ca, HB Fraser Primate cell fusion disentangles gene regulatory divergence in neurodevelopment Nature, 2021-03-17;0(0):. 2021-03-17 [PMID: 33731928] (Bioassay, Human, Primate)	Bioassay	Human, Primate
CV Latchouman, MI Betancur, GA Simchick, MK Sun, R Forghani, CE Lenear, A Ahmed, R Mohankumar, N Balaji, HD Mason, SA Archer-Har, P Azadi, PV Holmes, Q Zhao, RV Bellamkond, L Karumbaiah Engineered glycomaterial implants orchestrate large-scale functional repair of brain tissue chronically after severe traumatic brain injury Science Advances, 2021-03-05;7(10):. 2021-03-05 [PMID: 33674306] (Bioassay, Rat)	Bioassay	Rat
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AL Rodrigues, HY Liu, YW Chen, M Porotto, A Moscona, HW Snoeck The in vitro multilineage differentiation and maturation of lung and airway cells from human pluripotent stem cell-derived lung progenitors in 3D Nature Protocols, 2021-03-01;0(0):. 2021-03-01 [PMID: 33649566] (Bioassay, Human)	Bioassay	Human
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S Hao, X Zhu, Z Liu, X Wu, S Li, P Jiang, L Jiang Chronic intermittent hypoxia promoted lung cancer stem cell-like properties via enhancing Bach1 expression Respiratory Research, 2021-02-17;22(1):58. 2021-02-17 [PMID: 33596919] (Bioassay, Human)	Bioassay	Human
T Wang, AR Pine, AG Kotini, H Yuan, L Zamparo, DT Starczynow, C Leslie, EP Papapetrou Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets Cell Stem Cell, 2021-02-10;0(0):. 2021-02-10 [PMID: 33571445] (Bioassay, Human)	Bioassay	Human
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S Zhou, W Zhang, G Cai, Y Ding, C Wei, S Li, Y Yang, J Qin, D Liu, H Zhang, X Shao, J Wang, H Wang, W Yang, H Wang, S Chen, P Hu, L Sun Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration Cell Res., 2020-08-24;0(0):. 2020-08-24 [PMID: 32839552] (Bioassay, Mouse)	Bioassay	Mouse
S Eslava-Alc, MJ Extremera-, I Sanchez-Go, L Beltrán-Ca, A Rosal-Vela, J Muñoz, N Ibarz, JA Alonso-Piñ, M Rojas-Torr, M Jiménez-Pa, A González-R, R Conejero, E Doiz, M Rodriguez-, R Moreno-Lun, MC Durán-Ruiz Atherosclerotic Pre-Conditioning Affects the Paracrine Role of Circulating Angiogenic Cells Ex-Vivo Int J Mol Sci, 2020-07-24;21(15):. 2020-07-24 [PMID: 32722151] (Bioassay, Human)	Bioassay	Human
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CE Eyler, H Matsunaga, V Hovestadt, SJ Vantine, P van Galen, BE Bernstein Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance Genome Biol., 2020-07-15;21(1):174. 2020-07-15 [PMID: 32669109] (Cell Culture, Human)	Cell Culture	Human
K Hirano, M Kubo, Y Fukuyama, M Namihira Indonesian Ginger (Bangle) Extract Promotes Neurogenesis of Human Neural Stem Cells through WNT Pathway Activation Int J Mol Sci, 2020-07-05;21(13):. 2020-07-05 [PMID: 32635647] (Cell Culture, Human)	Cell Culture	Human
EJ Kim, YJ Kim, HI Lee, SH Jeong, HJ Nam, JH Cho NRF2 Knockdown Resensitizes 5-Fluorouracil-Resistant Pancreatic Cancer Cells by Suppressing HO-1 and ABCG2 Expression Int J Mol Sci, 2020-06-30;21(13):. 2020-06-30 [PMID: 32629871] (Cell Culture, Human)	Cell Culture	Human
E Gronseth, A Gupta, C Koceja, S Kumar, RG Kutty, K Rarick, L Wang, R Ramchandra Astrocytes influence medulloblastoma phenotypes and CD133 surface expression PLoS ONE, 2020-07-06;15(7):e0235852. 2020-07-06 [PMID: 32628717] (Cell Culture, Zebrafish)	Cell Culture	Zebrafish
LTP Khoa, YC Tsan, F Mao, DM Kremer, P Sajjakulnu, L Zhang, B Zhou, X Tong, NV Bhanu, C Choudhary, BA Garcia, L Yin, GD Smith, TL Saunders, SL Bielas, CA Lyssiotis, Y Dou Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation Cell Stem Cell, 2020-06-30;0(0):. 2020-06-30 [PMID: 32610040] (Bioassay, Human)	Bioassay	Human
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L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids Cell Stem Cell, 2020-06-19;27(1):125-136.e7. 2020-06-19 [PMID: 32579880] (Bioassay, Human)	Bioassay	Human
J Wu, D Song, Z Li, B Guo, Y Xiao, W Liu, L Liang, C Feng, T Gao, Y Chen, Y Li, Z Wang, J Wen, S Yang, P Liu, L Wang, Y Wang, L Peng, GN Stacey, Z Hu, G Feng, W Li, Y Huo, R Jin, N Shyh-Chang, Q Zhou, L Wang, B Hu, H Dai, J Hao Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis Cell Res., 2020-06-16;0(0):. 2020-06-16 [PMID: 32546764] (Bioassay, Human)	Bioassay	Human
BN Sheikh, S Guhathakur, TH Tsang, M Schwabenla, G Renschler, B Herquel, V Bhardwaj, H Holz, T Stehle, O Bondareva, N Aizarani, O Mossad, O Kretz, W Reichardt, A Chatterjee, LJ Braun, J Thevenon, H Sartelet, T Blank, D Grün, D von Elverf, TB Huber, D Vestweber, S Avilov, M Prinz, JM Buescher, A Akhtar Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature Nat. Cell Biol., 2020-06-15;0(0):. 2020-06-15 [PMID: 32541879] (Bioassay, Mouse)	Bioassay	Mouse
JA Gregory, E Hoelzli, R Abdelaal, C Braine, M Cuevas, M Halpern, N Barretto, N Schrode, G Akbalik, K Kang, E Cheng, K Bowles, S Lotz, S Goderie, CM Karch, S Temple, A Goate, KJ Brennand, H Phatnani Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models Cells, 2020-06-05;9(6):. 2020-06-05 [PMID: 32516938] (Cell Culture, Human)	Cell Culture	Human
J Wesely, AG Kotini, F Izzo, H Luo, H Yuan, J Sun, M Georgomano, A Zviran, AG Deslaurier, N Dusaj, SD Nimer, C Leslie, DA Landau, MG Kharas, EP Papapetrou Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells Cell Rep, 2020-06-02;31(9):107688. 2020-06-02 [PMID: 32492433] (Cell Culture, Human)	Cell Culture	Human
O Al-Dalahma, J Nicholson, S Draijer, LC Soares, FG Szele Galectin-3 diminishes Wnt signaling in the postnatal subventricular zone Stem Cells, 2020-06-08;0(0):. 2020-06-08 [PMID: 32442340] (Cell Culture, Mouse)	Cell Culture	Mouse
L Nimtz, J Hartmann, J Tigges, S Masjosthus, M Schmuck, E Ke beta el, S Theiss, K Köhrer, P Petzsch, J Adjaye, C Wigmann, D Wieczorek, B Hildebrand, F Bendt, U Hübenthal, G Brockerhof, E Fritsche Characterization and application of electrically active neuronal networks established from human induced pluripotent stem cell-derived neural progenitor cells for neurotoxicity evaluation Stem Cell Res, 2020-03-10;45(0):101761. 2020-03-10 [PMID: 32244191] (Bioassay, Human)	Bioassay	Human
YH Fang, SPH Wang, ZH Gao, SN Wu, HY Chang, PJ Yang, PY Liu, YW Liu Efficient Cardiac Differentiation of Human Amniotic Fluid-Derived Stem Cells into Induced Pluripotent Stem Cells and Their Potential Immune Privilege Int J Mol Sci, 2020-03-29;21(7):. 2020-03-29 [PMID: 32235313] (Cell Culture, Human)	Cell Culture	Human
SK Ryan, MV Gonzalez, JP Garifallou, FC Bennett, KS Williams, NP Sotuyo, E Mironets, K Cook, H Hakonarson, SA Anderson, KL Jordan-Sci Neuroinflammation and EIF2 Signaling Persist despite Antiretroviral Treatment in an hiPSC Tri-culture Model of HIV Infection Stem Cell Reports, 2020-03-26;0(0):. 2020-03-26 [PMID: 32220329] (Bioassay, Human)	Bioassay	Human
Z Chen, J Zhang, H Xue, M Qian, X Guo, X Gao, J Xu, Y Qi, X Sun, G Li Nitidine Chloride Is a Potential Alternative Therapy for Glioma Through Inducing Endoplasmic Reticulum Stress and Alleviating Epithelial-Mesenchymal Transition Integr Cancer Ther, 2020-01-01;19(0):1534735419900. 2020-01-01 [PMID: 32129091] (Bioassay, Human)	Bioassay	Human
HY Jo, HW Han, I Jung, JH Ju, SJ Park, S Moon, D Geum, H Kim, HJ Park, S Kim, GN Stacey, SK Koo, MH Park, JH Kim Development of genetic quality tests for good manufacturing practice-compliant induced pluripotent stem cells and their derivatives Sci Rep, 2020-03-03;10(1):3939. 2020-03-03 [PMID: 32127560] (Bioassay, Human)	Bioassay	Human
JS Kim, SI Hwang, JL Ryu, HS Hong, JM Lee, SM Lee, X Jin, C Han, JH Kim, J Han, MR Lee, DH Woo ER stress reliever enhances functionalities of in vitro cultured hepatocytes Stem Cell Res, 2020-02-12;43(0):101732. 2020-02-12 [PMID: 32087526] (Human)		Human
A Dicks, CL Wu, N Steward, SS Adkar, CA Gersbach, F Guilak Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter Stem Cell Res Ther, 2020-02-18;11(1):66. 2020-02-18 [PMID: 32070421] (Cell Culture, Human)	Cell Culture	Human
J Venkatesh, SC Sekhar, VT Cheriyan, M Muthu, P Meister, E Levi, S Dzinic, JW Gauld, LA Polin, AK Rishi Antagonizing binding of cell cycle and apoptosis regulatory protein 1 (CARP-1) to the NEMO/IKKgamma protein enhances the anticancer effect of chemotherapy J. Biol. Chem., 2020-02-04;295(11):3532-3552. 2020-02-04 [PMID: 32024692] (Bioassay, Human)	Bioassay	Human
Y Kim, S Lee, H Zhang, S Lee, H Kim, Y Kim, MH Won, YM Kim, YG Kwon CLEC14A deficiency exacerbates neuronal loss by increasing blood-brain barrier permeability and inflammation J Neuroinflammation, 2020-02-04;17(1):48. 2020-02-04 [PMID: 32019570] (Cell Culture, Human)	Cell Culture	Human
JH Lee, MR Shaker, E Lee, B Lee, W Sun NeuroCore formation during differentiation of neurospheres of mouse embryonic neural stem cells Stem Cell Res, 2020-01-18;43(0):101691. 2020-01-18 [PMID: 32018208] (Bioassay, Mouse)	Bioassay	Mouse
M Oatley, ÖV Bölükbas?, V Svensson, M Shvartsman, K Ganter, K Zirngibl, PV Pavlovich, V Milchevska, V Foteva, KN Natarajan, B Baying, V Benes, KR Patil, SA Teichmann, C Lancrin Single-cell transcriptomics identifies CD44 as a marker and regulator of endothelial to haematopoietic transition Nat Commun, 2020-01-29;11(1):586. 2020-01-29 [PMID: 31996681] (Cell Culture, Mouse)	Cell Culture	Mouse
AR Nickolls, MM Lee, DF Espinoza, M Szczot, RM Lam, Q Wang, J Beers, J Zou, MQ Nguyen, HJ Solinski, AA AlJanahi, KR Johnson, ME Ward, AT Chesler, CG Bönnemann Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells Cell Rep, 2020-01-21;30(3):932-946.e7. 2020-01-21 [PMID: 31968264] (Dififerentiation, Human)	Dififerentiation	Human
Y Yang, L Ding, Q Zhou, L Fen, Y Cao, J Sun, X Zhou, A Liu Silencing of AURKA augments the antitumor efficacy of the AURKA inhibitor MLN8237 on neuroblastoma cells Cancer Cell Int., 2020-01-07;20(0):9. 2020-01-07 [PMID: 31920463] (Bioassay, Human, Mouse)	Bioassay	Human, Mouse
D Suzuki, C Flahou, N Yoshikawa, I Stirblyte, Y Hayashi, A Sawaguchi, M Akasaka, S Nakamura, N Higashi, H Xu, T Matsumoto, K Fujio, MG Manz, A Hotta, H Takizawa, K Eto, N Sugimoto iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity Stem Cell Reports, 2019-12-26;0(0):. 2019-12-26 [PMID: 31883921] (Bioassay, Human)	Bioassay	Human
B You, F Mercier, E Assenat, C Langlois-J, O Glehen, J Soulé, L Payen, V Kepenekian, M Dupuy, F Belouin, E Morency, V Saywell, M Flacelière, P Elies, P Liaud, T Mazard, D Maucort-Bo, W Tan, B Vire, L Villeneuve, M Ychou, M Kohli, D Joubert, A Prieur The oncogenic and druggable hPG80 (Progastrin) is overexpressed in multiple cancers and detected in the blood of patients EBioMedicine, 2019-12-24;51(0):102574. 2019-12-24 [PMID: 31877416] (Bioassay, Human)	Bioassay	Human
D Chen, N Sun, L Hou, R Kim, J Faith, M Aslanyan, Y Tao, Y Zheng, J Fu, W Liu, M Kellis, A Clark Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors Cell Rep, 2019-12-24;29(13):4568-4582.e5. 2019-12-24 [PMID: 31875561] (Cell Culture, Human)	Cell Culture	Human
A Bonafina, MF Trinchero, AS Ríos, P Bekinschte, AF Schinder, G Paratcha, F Ledda GDNF and GFRalpha1 Are Required for Proper Integration of Adult-Born Hippocampal Neurons Cell Rep, 2019-12-24;29(13):4308-4319.e4. 2019-12-24 [PMID: 31875542] (Cell Culture, Mouse)	Cell Culture	Mouse
C Fisher, G Obaid, C Niu, W Foltz, A Goldstein, T Hasan, L Lilge Liposomal Lapatinib in Combination with Low-Dose Photodynamic Therapy for the Treatment of Glioma J Clin Med, 2019-12-14;8(12):. 2019-12-14 [PMID: 31847378] (Bioassay, Human)	Bioassay	Human
C Peng, L Lu, Y Li, J Hu Neurospheres induced from human adipose-derived stem cells as a new source of neural progenitor cells Cell Transplant, 2019-12-08;0(0):9636897198886. 2019-12-08 [PMID: 31813268] (Bioassay, Human)	Bioassay	Human
M Ali, F Kabir, JJ Thomson, Y Ma, C Qiu, M Delannoy, SY Khan, SA Riazuddin Comparative transcriptome analysis of hESC- and iPSC-derived lentoid bodies Sci Rep, 2019-12-06;9(1):18552. 2019-12-06 [PMID: 31811247] (Bioassay, Human)	Bioassay	Human
S Weber, SE Koschade, CM Hoffmann, TD Dubash, KM Giessler, SM Dieter, F Herbst, H Glimm, CR Ball The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo BMC Cancer, 2019-12-03;19(1):1181. 2019-12-03 [PMID: 31796022] (Bioassay, Human)	Bioassay	Human
D Hao, C He, B Ma, L Lankford, L Reynaga, DL Farmer, F Guo, A Wang Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering Stem Cells Int, 2019-11-12;2019(0):9695239. 2019-11-12 [PMID: 31781252] (Tissue Culture, Human)	Tissue Culture	Human
M Vermeulen, F Del Vento, M Kanbar, S Pyr Dit Ru, D Vertommen, J Poels, C Wyns Generation of Organized Porcine Testicular Organoids in Solubilized Hydrogels from Decellularized Extracellular Matrix Int J Mol Sci, 2019-11-03;20(21):. 2019-11-03 [PMID: 31684200] (Bioassay, Porcine)	Bioassay	Porcine
Y Koutmani, IA Gampieraki, A Polissidis, M Ximerakis, PN Koutsoudak, A Polyzos, G Agrogianni, S Karaliota, D Thomaidou, LL Rubin, PK Politis, KP Karalis CRH Promotes the Neurogenic Activity of Neural Stem Cells in the Adult Hippocampus Cell Rep, 2019-10-22;29(4):932-945.e7. 2019-10-22 [PMID: 31644914] (Bioassay, Mouse)	Bioassay	Mouse
A Tripathi, C Volsko, JP Garcia, E Agirre, KC Allan, PJ Tesar, BD Trapp, G Castelo-Br, FJ Sim, R Dutta Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination Cell Rep, 2019-10-22;29(4):904-919.e9. 2019-10-22 [PMID: 31644912] (Bioassay, Mouse)	Bioassay	Mouse
J Chen, B Ananthanar, KS Springer, KJ Wolf, SM Sheyman, VD Tran, S Kumar Suppression of LIM Kinase 1 and LIM Kinase 2 Limits Glioblastoma Invasion Cancer Res., 2019-10-22;0(0):. 2019-10-22 [PMID: 31641031] (Bioassay, Human)	Bioassay	Human
F Inoue, A Kreimer, T Ashuach, N Ahituv, N Yosef Identification and Massively Parallel Characterization of Regulatory Elements Driving Neural Induction Cell Stem Cell, 2019-10-17;0(0):. 2019-10-17 [PMID: 31631012] (Bioassay, Human)	Bioassay	Human
T Yung, F Poon, M Liang, S Coquenlorg, EC McGaugh, CC Hui, MD Wilson, MC Nostro, TH Kim Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals Nat Commun, 2019-10-11;10(1):4647. 2019-10-11 [PMID: 31604927] (Bioassay, Human)	Bioassay	Human
R Liu, X Zhang, Z Fan, Y Wang, G Yao, X Wan, Z Liu, B Yang, L Yu Human amniotic mesenchymal stem cells improve the follicular microenvironment to recover ovarian function in premature ovarian failure mice Stem Cell Res Ther, 2019-10-02;10(1):299. 2019-10-02 [PMID: 31578152] (Bioassay, Human)	Bioassay	Human
T Tabata, M Petitt, J Fang-Hoove, DC Freed, F Li, Z An, D Wang, TM Fu, L Pereira Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas Vaccines (Basel), 2019-09-29;7(4):. 2019-09-29 [PMID: 31569508] (Bioassay, Human)	Bioassay	Human
Q Mei, A Bansal, MKG Jayakumar, Z Zhang, J Zhang, H Huang, D Yu, CJA Ramachandr, DJ Hausenloy, TW Soong, Y Zhang Manipulating energy migration within single lanthanide activator for switchable upconversion emissions towards bidirectional photoactivation Nat Commun, 2019-09-27;10(1):4416. 2019-09-27 [PMID: 31562321] (Bioassay, Human)	Bioassay	Human
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CY Lee, TJ Huang, MH Wu, YY Li, KD Lee High Expression of Acid-Sensing Ion Channel 2 (ASIC2) in Bone Cells in Osteoporotic Vertebral Fractures Biomed Res Int, 2019-08-19;2019(0):4714279. 2019-08-19 [PMID: 31531354] (Bioassay, Human)	Bioassay	Human
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J Domingo-Pr, V Abad-Moral, M Riera, R Navarro, B Corcostegu, E Pomares Generation of an induced pluripotent stem cell line (FRIMOi007-A) derived from an incomplete achromatopsia patient carrying a novel homozygous mutation in PDE6C gene Stem Cell Res, 2019-09-04;40(0):101569. 2019-09-04 [PMID: 31520890] (Cell Culture, Human)	Cell Culture	Human
J Domingo-Pr, M Riera, V Abad-Moral, S Ruiz-Nogal, B Corcostegu, E Pomares Generation of Best disease-derived induced pluripotent stem cell line (FRIMOi006-A) carrying a novel dominant mutation in BEST1 gene Stem Cell Res, 2019-09-04;40(0):101570. 2019-09-04 [PMID: 31518904] (Cell Culture, Human)	Cell Culture	Human
KM Walter, K Dach, K Hayakawa, S Giersiefer, H Heuer, PJ Lein, E Fritsche Ontogenetic expression of thyroid hormone signaling genes: An in vitro and in vivo species comparison PLoS ONE, 2019-09-12;14(9):e0221230. 2019-09-12 [PMID: 31513589] (Bioassay, Human, Rat)	Bioassay	Human, Rat
Y Shen, K Pu, K Zheng, X Ma, J Qin, L Jiang, J Li Differentially Expressed microRNAs in MIA PaCa-2 and PANC-1 Pancreas Ductal Adenocarcinoma Cell Lines are Involved in Cancer Stem Cell Regulation Int J Mol Sci, 2019-09-10;20(18):. 2019-09-10 [PMID: 31510100] (Bioassay, Human)	Bioassay	Human
V Ravi, AB Madhankuma, T Abraham, B Slagle-Web, JR Connor Liposomal delivery of ferritin heavy chain 1 (FTH1) siRNA in patient xenograft derived glioblastoma initiating cells suggests different sensitivities to radiation and distinct survival mechanisms PLoS ONE, 2019-09-06;14(9):e0221952. 2019-09-06 [PMID: 31491006] (Bioassay, Human)	Bioassay	Human
SP Hong, TE Chan, Y Lombardo, G Corleone, N Rotmensz, S Bravaccini, A Rocca, G Pruneri, KR McEwen, RC Coombes, I Barozzi, L Magnani Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy Nat Commun, 2019-09-02;10(1):3840. 2019-09-02 [PMID: 31477698] (Cell Culture, Human)	Cell Culture	Human
J Tiihonen, M Koskuvi, M Lähteenvuo, PLJ Virtanen, I Ojansuu, O Vaurio, Y Gao, I Hyötyläine, KA Puttonen, E Repo-Tiiho, T Paunio, MR Rautiainen, S Tyni, J Koistinaho, Š Lehtonen Neurobiological roots of psychopathy Mol. Psychiatry, 2019-08-27;0(0):. 2019-08-27 [PMID: 31455857] (Bioassay, Human)	Bioassay	Human
L Messerschm, S Fischer, P Wiedemann, A Bringmann, M Hollborn Osmotic induction of cyclooxygenase-2 in RPE cells: Stimulation of inflammasome activation Mol. Vis., 2019-06-30;25(0):329-344. 2019-06-30 [PMID: 31341381] (Bioassay, Human)	Bioassay	Human
SB Yoon, YH Park, SA Choi, HJ Yang, PS Jeong, JJ Cha, S Lee, SH Lee, JH Lee, BW Sim, BS Koo, SJ Park, Y Lee, YH Kim, JJ Hong, JS Kim, YB Jin, JW Huh, SR Lee, BS Song, SU Kim Real-time PCR quantification of spliced X-box binding protein 1 (XBP1) using a universal primer method PLoS ONE, 2019-07-22;14(7):e0219978. 2019-07-22 [PMID: 31329612] (Cell Culture, Bovine, Macaca fascicularis (cynomolgus monkey), Mouse, Porcine)	Cell Culture	Bovine, Macaca fascicularis (cynomolgus monkey), Mouse, Porcine
S Tongkobpet, R Rungsiwiwu, K Pruksanano, K Suphapeeti, V Shotelersu Generation of two human iPSC lines (MDCUi001-A and MDCUi001-B) from dermal fibroblasts of a Thai patient with X-linked osteogenesis imperfecta using integration-free Sendai virus Stem Cell Res, 2019-06-29;39(0):101493. 2019-06-29 [PMID: 31326747] (Bioassay, Human)	Bioassay	Human
TC Lin, YY Lin, CC Hsu, YP Yang, CH Yang, DK Hwang, CY Wang, YY Liu, WL Lo, SH Chiou, CH Peng, SJ Chen, YL Chang Nanomedicine-based Curcumin Approach Improved ROS Damage in Best Dystrophy-specific Induced Pluripotent Stem Cells Cell Transplant, 2019-07-17;0(0):9636897198601. 2019-07-17 [PMID: 31313605] (Bioassay, Human)	Bioassay	Human
S Pecha, K Yorgan, M Röhl, B Geertz, A Hansen, F Weinberger, S Sehner, H Ehmke, H Reichenspu, T Eschenhage, AP Schwoerer Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model Sci Rep, 2019-07-08;9(1):9831. 2019-07-08 [PMID: 31285568] (Cell Culture, Human)	Cell Culture	Human
SH Yang, M Andrabi, R Biss, S Murtuza Ba, M Iqbal, AD Sharrocks ZIC3 Controls the Transition from Naive to Primed Pluripotency Cell Rep, 2019-06-11;27(11):3215-3227.e6. 2019-06-11 [PMID: 31189106] (Bioassay, Mouse)	Bioassay	Mouse
J Domingo-Pr, M Riera, A Burés-Jels, B Corcostegu, E Pomares Establishment of an induced pluripotent stem cell line (FRIMOi005-A) derived from a retinitis pigmentosa patient carrying a dominant mutation in RHO gene Stem Cell Res, 2019-05-22;38(0):101468. 2019-05-22 [PMID: 31146251] (Bioassay, Human)	Bioassay	Human
M Meijer, K Rehbach, JW Brunner, JA Classen, HCA Lammertse, LA van Linge, D Schut, T Krutenko, M Hebisch, LN Cornelisse, PF Sullivan, M Peitz, RF Toonen, O Brüstle, M Verhage A Single-Cell Model for Synaptic Transmission and Plasticity in Human iPSC-Derived Neurons Cell Rep, 2019-05-14;27(7):2199-2211.e6. 2019-05-14 [PMID: 31091456] (Bioassay, Human)	Bioassay	Human
N Kawai, Y Hirohashi, Y Ebihara, T Saito, A Murai, T Saito, T Shirosaki, T Kubo, M Nakatsugaw, T Kanaseki, T Tsukahara, T Shichinohe, L Li, S Hirano, T Torigoe ABCG2 expression is related to low 5-ALA photodynamic diagnosis (PDD) efficacy and cancer stem cell phenotype, and suppression of ABCG2 improves the efficacy of PDD PLoS ONE, 2019-05-13;14(5):e0216503. 2019-05-13 [PMID: 31083682] (Bioassay, Human)	Bioassay	Human
ML Shiao, C Yuan, AT Crane, JP Voth, M Juliano, LLH Stone, Z Nan, Y Zhang, N Kuzmin-Nic, PR Sanberg, AW Grande, WC Low Immunomodulation with Human Umbilical Cord Blood Stem Cells Ameliorates Ischemic Brain Injury - A Brain Transcriptome Profiling Analysis Cell Transplant, 2019-05-08;0(0):9636897198367. 2019-05-08 [PMID: 31066288] (Bioassay, Human)	Bioassay	Human
A Hall, K Choi, W Liu, J Rose, C Zhao, Y Yu, Y Na, Y Cai, RA Coover, Y Lin, E Dombi, M Kim, D Levanon, Y Groner, E Boscolo, D Pan, PP Liu, QR Lu, N Ratner, G Huang, J Wu RUNX represses Pmp22 to drive neurofibromagenesis Sci Adv, 2019-04-24;5(4):eaau8389. 2019-04-24 [PMID: 31032403] (Bioassay, Mouse)	Bioassay	Mouse
EE Mulkearns-, LA Torre-Heal, DJ Silver, JT Eurich, D Bayik, E Serbinowsk, M Hitomi, J Zhou, B Przychodze, R Zhang, SA Sprowls, JS Hale, TJ Alban, A Berezovsky, BA Bell, PR Lockman, BK Jha, JD Lathia Development of a Cx46 Targeting Strategy for Cancer Stem Cells Cell Rep, 2019-04-23;27(4):1062-1072.e5. 2019-04-23 [PMID: 31018124] (Bioassay, Xenograft)	Bioassay	Xenograft
L Sun, F Wang, H Chen, D Liu, T Qu, X Li, D Xu, F Liu, Z Yin, Y Chen Co-Transplantation of Human Umbilical Cord Mesenchymal Stem Cells and Human Neural Stem Cells Improves the Outcome in Rats with Spinal Cord Injury Cell Transplant, 2019-04-23;0(0):9636897198445. 2019-04-23 [PMID: 31012325] (Bioassay, Human)	Bioassay	Human
M Urbischek, H Rannikmae, T Foets, K Ravn, M Hyvönen, M de la Roch Organoid culture media formulated with growth factors of defined cellular activity Sci Rep, 2019-04-17;9(1):6193. 2019-04-17 [PMID: 30996238] (Bioassay, Human)	Bioassay	Human
G MacLeod, DA Bozek, N Rajakulend, V Monteiro, M Ahmadi, Z Steinhart, MM Kushida, H Yu, FJ Coutinho, FMG Cavalli, I Restall, X Hao, T Hart, HA Luchman, S Weiss, PB Dirks, S Angers Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells Cell Rep, 2019-04-16;27(3):971-986.e9. 2019-04-16 [PMID: 30995489] (Bioassay, Human)	Bioassay	Human
B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, JJ Kwan, KR Brown, E Titus, M Atkins, KSK Chan, L Munsie, A Habsid, H Han, M Kennedy, B Cohen, G Keller, J Moffat Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies Cell Rep, 2019-04-09;27(2):599-615.e12. 2019-04-09 [PMID: 30970261] (Differentiation, Differentiation, Human)	Differentiation, Differentiation	Human
T Ryynänen, A Pelkonen, K Grigoras, OME Ylivaara, T Hyvärinen, J Ahopelto, M Prunnila, S Narkilahti, J Lekkala Microelectrode Array With Transparent ALD TiN Electrodes Front Neurosci, 2019-03-22;13(0):226. 2019-03-22 [PMID: 30967754] (Bioassay, Human)	Bioassay	Human
SFB Fadhlullah, NBA Halim, JYT Yeo, RLY Ho, P Um, BT Ang, C Tang, WH Ng, DM Virshup, IAW Ho Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness Oncogene, 2019-04-09;38(27):5367-5380. 2019-04-09 [PMID: 30967630] (Bioassay, Human)	Bioassay	Human
S Varum, A Baggiolini, L Zurkirchen, ZK Atak, C Cantù, E Marzorati, R Bossart, J Wouters, J Häusel, E Tuncer, D Zingg, D Veen, N John, M Balz, MP Levesque, K Basler, S Aerts, N Zamboni, R Dummer, L Sommer Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation Cell Stem Cell, 2019-04-04;24(4):637-653.e9. 2019-04-04 [PMID: 30951662] (Bioassay, Mouse)	Bioassay	Mouse
M Matsushita, Y Mori, K Uchiumi, T Ogata, M Nakamura, H Yoda, H Soda, N Takiguchi, Y Nabeya, O Shimozato, T Ozaki PTPRK suppresses progression and chemo-resistance of colon cancer cells via direct inhibition of pro-oncogenic CD133 FEBS Open Bio, 2019-04-18;0(0):. 2019-04-18 [PMID: 30947381] (Bioassay, Human)	Bioassay	Human
M Rutgers, F Bach, L Vonk, M van Rijen, V Akrum, A van Boxtel, W Dhert, L Creemers PTH decreases in vitro human cartilage regeneration without affecting hypertrophic differentiation PLoS ONE, 2019-04-04;14(4):e0213483. 2019-04-04 [PMID: 30947269] (Bioassay, Human)	Bioassay	Human
HL Zhang, P Wang, MZ Lu, SD Zhang, L Zheng c-Myc maintains the self-renewal and chemoresistance properties of colon cancer stem cells Oncol Lett, 2019-02-28;17(5):4487-4493. 2019-02-28 [PMID: 30944638] (Bioassay, Human)	Bioassay	Human
K Itoh, S Masumori, D Mukai, H Sakakibara, M Yasuda, K Shimoi Dosage time affects alkylating agents induced micronuclei in mouse peripheral blood reticulocytes through the function of erythropoietin J Toxicol Sci, 2019-01-01;44(4):273-282. 2019-01-01 [PMID: 30944280] (In Vivo, Mouse)	In Vivo	Mouse
Z Shen, C Zhang, L Qu, C Lu, M Xiao, R Ni, J Liu MKP-4 suppresses hepatocarcinogenesis by targeting ERK1/2 pathway Cancer Cell Int., 2019-03-18;19(0):61. 2019-03-18 [PMID: 30923463] (Bioassay, Human)	Bioassay	Human
K Barber, L Studer, F Fattahi Derivation of enteric neuron lineages from human pluripotent stem cells Nat Protoc, 2019-03-25;14(4):1261-1279. 2019-03-25 [PMID: 30911172] (Bioassay, Human)	Bioassay	Human
Z Wang, L Kang, H Zhang, Y Huang, L Fang, M Li, PJ Brown, CH Arrowsmith, J Li, J Wong AKT drives SOX2 overexpression and cancer cell stemness in esophageal cancer by protecting SOX2 from UBR5-mediated degradation Oncogene, 2019-03-20;0(0):. 2019-03-20 [PMID: 30894683] (Bioassay, Human)	Bioassay	Human
MA Ajmone-Cat, A Onori, C Toselli, E Stronati, M Morlando, I Bozzoni, E Monni, Z Kokaia, G Lupo, L Minghetti, S Biagioni, E Cacci Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death Sci Rep, 2019-03-14;9(1):4572. 2019-03-14 [PMID: 30872738] (Bioassay, Human)	Bioassay	Human
N Funk, M Munz, T Ott, K Brockmann, A Wenninger-, R Kühn, D Vogt-Weise, F Giesert, W Wurst, T Gasser, S Biskup The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4 Sci Rep, 2019-03-14;9(1):4515. 2019-03-14 [PMID: 30872638] (Bioassay, Mouse)	Bioassay	Mouse
H Xu, B Wang, M Ono, A Kagita, K Fujii, N Sasakawa, T Ueda, P Gee, M Nishikawa, M Nomura, F Kitaoka, T Takahashi, K Okita, Y Yoshida, S Kaneko, A Hotta Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility Cell Stem Cell, 2019-03-07;0(0):. 2019-03-07 [PMID: 30853558] (Bioassay, Human)	Bioassay	Human
N Naldaiz-Ga, M Goicoechea, IM Aragón, V Pérez-Lópe, S Fuertes-Al, B Herrera-Im, A López de M, R de Luna-Di, PM Baptista, MA Fernández, MF Lara, A Izeta Isolation and characterization of myogenic precursor cells from human cremaster muscle Sci Rep, 2019-03-05;9(1):3454. 2019-03-05 [PMID: 30837559] (Bioassay, Human)	Bioassay	Human
YP Xu, Y Qiu, B Zhang, G Chen, Q Chen, M Wang, F Mo, J Xu, J Wu, RR Zhang, ML Cheng, NN Zhang, B Lyu, WL Zhu, MH Wu, Q Ye, D Zhang, JH Man, XF Li, J Cui, Z Xu, B Hu, X Zhou, CF Qin Zika virus infection induces RNAi-mediated antiviral immunity in human neural progenitors and brain organoids Cell Res., 2019-02-27;0(0):. 2019-02-27 [PMID: 30814679] (Bioassay, Human)	Bioassay	Human
J Ooi, SR Langley, X Xu, KH Utami, B Sim, Y Huang, NP Harmston, YL Tay, A Ziaei, R Zeng, D Low, F Aminkeng, RM Sobota, F Ginhoux, E Petretto, MA Pouladi Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects Cell Rep, 2019-02-26;26(9):2494-2508.e7. 2019-02-26 [PMID: 30811996]
M Riera, A Patel, A Burés-Jels, B Corcostegu, S Chang, E Pomares, B Corneo, JR Sparrow Generation of two iPS cell lines (FRIMOi003-A and FRIMOi004-A) derived from Stargardt patients carrying ABCA4 compound heterozygous mutations Stem Cell Res, 2019-02-13;36(0):101389. 2019-02-13 [PMID: 30798147] (Bioassay, Human)	Bioassay	Human
N Muraoka, K Nara, F Tamura, H Kojima, H Yamakawa, T Sadahiro, K Miyamoto, M Isomi, S Haginiwa, H Tani, S Kurotsu, R Osakabe, S Torii, S Shimizu, H Okano, Y Sugimoto, K Fukuda, M Ieda Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming Nat Commun, 2019-02-20;10(1):674. 2019-02-20 [PMID: 30787297] (Bioassay, Mouse)	Bioassay	Mouse
M Kunova Bos, A Nita, T Gregor, M Varecha, I Gudernova, B Fafilek, T Barta, N Basheer, SP Abraham, L Balek, M Tomanova, J Fialova Ku, J Bosak, D Potesil, J Zieba, J Song, P Konik, S Park, I Duran, Z Zdrahal, D Smajs, G Jansen, Z Fu, HW Ko, A Hampl, L Trantirek, D Krakow, P Krejci Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase Proc. Natl. Acad. Sci. U.S.A., 2019-02-19;0(0):. 2019-02-19 [PMID: 30782830] (Bioassay, Human)	Bioassay	Human
TS Winston, K Suddhapas, C Wang, R Ramos, P Soman, Z Ma Serum-Free Manufacturing of Mesenchymal Stem Cell Tissue Rings Using Human-Induced Pluripotent Stem Cells Stem Cells Int, 2019-01-15;2019(0):5654324. 2019-01-15 [PMID: 30766604] (Bioassay, Human)	Bioassay	Human
E Ito, S Miyagawa, M Takeda, A Kawamura, A Harada, H Iseoka, S Yajima, N Sougawa, N Mochizuki-, S Yasuda, Y Sato, Y Sawa Tumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application Sci Rep, 2019-02-13;9(1):1881. 2019-02-13 [PMID: 30760836] (Bioassay, Human)	Bioassay	Human
JH Wang, ST Huang, L Zhang, ZG Liu, RX Liang, SW Jiang, YN Jiang, XJ Yu, YC Jiang, XZ Li, PF Zhang, ZS Wen, M Zheng Combined prognostic value of the cancer stem cell markers CD47 and CD133 in esophageal squamous cell carcinoma Cancer Med, 2019-02-11;0(0):. 2019-02-11 [PMID: 30741466] (Bioassay, Human)	Bioassay	Human
S Bunda, P Heir, J Metcalf, ASC Li, S Agnihotri, S Pusch, M Yasin, M Li, K Burrell, S Mansouri, O Singh, M Wilson, A Alamsahebp, R Nejad, B Choi, D Kim, A von Deimli, G Zadeh, K Aldape CIC protein instability contributes to tumorigenesis in glioblastoma Nat Commun, 2019-02-08;10(1):661. 2019-02-08 [PMID: 30737375] (Bioassay, Human)	Bioassay	Human
S Ashraf, S Bell, C O'Leary, P Canning, I Micu, JA Fernandez, M O'Hare, P Barabas, H McCauley, DP Brazil, AW Stitt, JG McGeown, TM Curtis CAMKII as a therapeutic target for growth factor-induced retinal and choroidal neovascularisation JCI Insight, 2019-03-21;0(0):. 2019-03-21 [PMID: 30721154] (Bioassay, Human)	Bioassay	Human
JH Jo, SB Park, S Park, HS Lee, C Kim, DE Jung, SY Song Novel Gastric Cancer Stem Cell-Related Marker LINGO2 Is Associated with Cancer Cell Phenotype and Patient Outcome Int J Mol Sci, 2019-01-28;20(3):. 2019-01-28 [PMID: 30696080] (Bioassay, Human)	Bioassay	Human
M Riera, A Patel, B Corcostegu, S Chang, B Corneo, JR Sparrow, E Pomares Generation of an induced pluripotent stem cell line (FRIMOi002-A) from a retinitis pigmentosa patient carrying compound heterozygous mutations in USH2A gene Stem Cell Res, 2019-01-17;35(0):101386. 2019-01-17 [PMID: 30685615] (Bioassay, Human)	Bioassay	Human
M Riera, A Patel, B Corcostegu, S Chang, JR Sparrow, E Pomares, B Corneo Establishment and characterization of an iPSC line (FRIMOi001-A) derived from a retinitis pigmentosa patient carrying PDE6A mutations Stem Cell Res, 2019-01-17;35(0):101385. 2019-01-17 [PMID: 30685614] (Bioassay, Human)	Bioassay	Human
A Montel-Hag, CS Seet, S Li, B Chick, Y Zhu, P Chang, S Tsai, V Sun, S Lopez, HC Chen, C He, CJ Chin, D Casero, GM Crooks Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells Cell Stem Cell, 2019-01-17;0(0):. 2019-01-17 [PMID: 30661959] (Bioassay)	Bioassay
SZ Kuo, CO Honda, WT Li, TK Honda, E Kim, X Altuna, E Abhold, J Wang-Rodri, WM Ongkeko Metformin Results in Diametrically Opposed Effects by Targeting Non-Stem Cancer Cells but Protecting Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma Int J Mol Sci, 2019-01-07;20(1):. 2019-01-07 [PMID: 30621095] (Bioassay, Human)	Bioassay	Human
JA Maguire, AL Gagne, P Gonzalez-A, BL Davidson, V Shakkottai, P Gadue, DL French Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN2 gene Stem Cell Res, 2018-12-10;34(0):101361. 2018-12-10 [PMID: 30611021] (Bioassay, Human)	Bioassay	Human
D Chen, W Liu, J Zimmerman, WA Pastor, R Kim, L Hosohama, J Ho, M Aslanyan, JJ Gell, SE Jacobsen, AT Clark The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation Cell Rep, 2018-12-26;25(13):3591-3602.e5. 2018-12-26 [PMID: 30590035] (Bioassay, Human)	Bioassay	Human
SJ Yoon, LS Elahi, AM Pa?ca, RM Marton, A Gordon, O Revah, Y Miura, EM Walczak, GM Holdgate, HC Fan, JR Huguenard, DH Geschwind, SP Pa?ca Reliability of human cortical organoid generation Nat. Methods, 2018-12-20;16(1):75-78. 2018-12-20 [PMID: 30573846] (Bioassay, Human)	Bioassay	Human
S Schwager, S Renner, T Hemmerle, S Karaman, ST Proulx, R Fetz, AM Golding-Oc, P Probst, C Halin, D Neri, M Detmar Antibody-mediated delivery of VEGF-C potently reduces chronic skin inflammation JCI Insight, 2018-12-06;3(23):. 2018-12-06 [PMID: 30518687] (Bioassay, Human)	Bioassay	Human
J Park, JH Lee, BS Yoon, EK Jun, G Lee, IY Kim, S You Additive effect of bFGF and selenium on expansion and paracrine action of human amniotic fluid-derived mesenchymal stem cells Stem Cell Res Ther, 2018-11-08;9(1):293. 2018-11-08 [PMID: 30409167] (Bioassay, Human)	Bioassay	Human
K Huang, Y Zhu, Y Ma, B Zhao, N Fan, Y Li, H Song, S Chu, Z Ouyang, Q Zhang, Q Xing, C Lai, N Li, T Zhang, J Gu, B Kang, Y Shan, K Lai, W Huang, Y Mai, Q Wang, J Li, A Lin, Y Zhang, X Zhong, B Liao, L Lai, J Chen, D Pei, G Pan BMI1 enables interspecies chimerism with human pluripotent stem cells Nat Commun, 2018-11-07;9(1):4649. 2018-11-07 [PMID: 30405129] (Bioassay, Human)	Bioassay	Human
IF LaRocque-d, JDB Rocha, MP Nunes, PAV Oliveira, DO Nascimento, L Freire-de-, CM Takiya, A Morrot, D Decote-Ric, JO Previato, GA DosReis, L Mendonça-P, CG Freire-de- Involvement of the capsular GalXM-induced IL-17 cytokine in the control of Cryptococcus neoformans infection Sci Rep, 2018-11-06;8(1):16378. 2018-11-06 [PMID: 30401972] (Bioassay, Human)	Bioassay	Human
H Takeuchi, S Inagaki, W Morozumi, Y Nakano, Y Inoue, Y Kuse, T Mizoguchi, S Nakamura, M Funato, H Kaneko, H Hara, M Shimazawa VGF nerve growth factor inducible is involved in retinal ganglion cells death induced by optic nerve crush Sci Rep, 2018-11-06;8(1):16443. 2018-11-06 [PMID: 30401804] (Bioassay, Human)	Bioassay	Human
JY Yeon, JY Hwang, HW Lee, HJ Pyeon, JS Won, YJ Noh, H Nam, KM Joo Optimized Clump Culture Methods for Adult Human Multipotent Neural Cells Int J Mol Sci, 2018-10-29;19(11):. 2018-10-29 [PMID: 30380605] (Bioassay, Human)	Bioassay	Human
SS Adkar, CL Wu, VP Willard, A Dicks, A Ettyreddy, N Steward, N Bhutani, CA Gersbach, F Guilak Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing Stem Cells, 2018-10-31;0(0):. 2018-10-31 [PMID: 30378731] (Bioassay, Human)	Bioassay	Human
B Readhead, BJ Hartley, BJ Eastwood, DA Collier, D Evans, R Farias, C He, G Hoffman, P Sklar, JT Dudley, EE Schadt, R Savi?, KJ Brennand Expression-based drug screening of neural progenitor cells from individuals with schizophrenia Nat Commun, 2018-10-24;9(1):4412. 2018-10-24 [PMID: 30356048] (Bioassay, Human)	Bioassay	Human
A Omer Javed, Y Li, J Muffat, KC Su, MA Cohen, T Lungjangwa, P Aubourg, IM Cheeseman, R Jaenisch Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype Cell Rep, 2018-10-09;25(2):368-382.e5. 2018-10-09 [PMID: 30304678] (Bioassay, Human)	Bioassay	Human
Y Zhang, Y Yang, M Jiang, SX Huang, W Zhang, D Al Alam, S Danopoulos, M Mori, YW Chen, R Balasubram, SM Chuva de S, C Serra, M Bialecka, E Kim, S Lin, ALR Toste de C, PN Riccio, WV Cardoso, X Zhang, HW Snoeck, J Que 3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling Cell Stem Cell, 2018-09-20;0(0):. 2018-09-20 [PMID: 30244870] (Bioassay, Human)	Bioassay	Human
A Skrzypczyk, S Kehr, I Krystel, SH Bernhart, S Giri, A Bader, PF Stadler Noncoding RNA Transcripts during Differentiation of Induced Pluripotent Stem Cells into Hepatocytes Stem Cells Int, 2018-08-19;2018(0):5692840. 2018-08-19 [PMID: 30210551] (Bioassay, Human)	Bioassay	Human
SA Sloan, J Andersen, AM Pa?ca, F Birey, SP Pa?ca Generation and assembly of human brain region-specific three-dimensional cultures Nat Protoc, 2018-09-01;0(0):. 2018-09-01 [PMID: 30202107] (Cell Culture, Human)	Cell Culture	Human
D Kim, BH Choi, IG Ryoo, MK Kwak High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenaseï¿½(ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling Cell Death Dis, 2018-08-30;9(9):896. 2018-08-30 [PMID: 30166520] (Bioassay, Human)	Bioassay	Human
LS Pane, FG Fulcoli, A Cirino, A Altomonte, R Ferrentino, M Bilio, A Baldini Tbx1 represses Mef2c gene expression and is correlated with histone 3 deacetylation of the anterior heart field enhancer Dis Model Mech, 2018-08-30;11(9):. 2018-08-30 [PMID: 30166330] (Bioassay, Human)	Bioassay	Human
Z Liu, Y Wei, L Zhang, PP Yee, M Johnson, X Zhang, M Gulley, JM Atkinson, M Trebak, HG Wang, W Li Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ Oncogene, 2018-08-06;38(1):120-139. 2018-08-06 [PMID: 30082911] (Bioassay, Human)	Bioassay	Human
P Nikolakopo, A Chatzigeor, I Kourtzelis, L Toutouna, J Masjkur, C Arps-Forke, SW Poser, J Rozman, B Rathkolb, JA Aguilar-Pi, E Wolf, M Klingenspo, M Ollert, C Schmidt-We, H Fuchs, V Gailus-Dur, M Hrabe de A, V Tsata, LS Monasor, M Troullinak, A Witt, V Anastasiou, G Chrousos, CX Yi, C García-Các, MH Tschöp, SR Bornstein, A Androutsel Streptozotocin-induced ?-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain Sci Rep, 2018-07-27;8(1):11335. 2018-07-27 [PMID: 30054579] (Bioassay, Mouse)	Bioassay	Mouse
Z Hubler, D Allimuthu, I Bederman, MS Elitt, M Madhavan, KC Allan, HE Shick, E Garrison, M T Karl, DC Factor, ZS Nevin, JL Sax, MA Thompson, Y Fedorov, J Jin, WK Wilson, M Giera, F Bracher, RH Miller, PJ Tesar, DJ Adams Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination Nature, 2018-07-25;0(0):. 2018-07-25 [PMID: 30046109] (Bioassay, Human)	Bioassay	Human
KH Lee, HJ Pyeon, H Nam, JS Won, JY Hwang, KA Lee, JY Yeon, SC Hong, DH Nam, K Lee, SH Lee, KM Joo Significant therapeutic effects of adult human multipotent neural cells on spinal cord injury Stem Cell Res, 2018-07-19;31(0):71-78. 2018-07-19 [PMID: 30031233] (Bioassay, Human)	Bioassay	Human
M Sladkova, R Alawadhi, R Jaragh Alh, A Esmael, S Alansari, M Saad, J Mulla Yous, L Alqaoud, GM de Peppo Segmental Additive Tissue Engineering Sci Rep, 2018-07-18;8(1):10895. 2018-07-18 [PMID: 30022102] (Bioassay, Human)	Bioassay	Human
SS Chan, RW Arpke, A Filareto, N Xie, MP Pappas, JS Penaloza, RCR Perlingeir, M Kyba Skeletal Muscle Stem Cells from PSC-Derived Teratomas Have Functional Regenerative Capacity Cell Stem Cell, 2018-07-05;23(1):74-85.e6. 2018-07-05 [PMID: 29979993] (Bioassay, Mouse)	Bioassay	Mouse
X Meng, W Su, X Tao, M Sun, R Ying, W Wei, B Wang Oxidation Prevents HMGB1 Inhibition on PDGF-Induced Differentiation of Multipotent Vascular Stem Cells to Smooth Muscle Cells: A Possible Mechanism Linking Oxidative Stress to Atherosclerosis Biomed Res Int, 2018-05-23;2018(0):4019814. 2018-05-23 [PMID: 29951536] (Bioassay, Rat)	Bioassay	Rat
CH Peng, LC Woung, KH Lu, CY Tsai, SD Lee, CS Huang, TC Lin, KH Chien, DK Hwang Acoustic waves improves retroviral transduction in human retinal stem cells J Chin Med Assoc, 2018-06-22;0(0):. 2018-06-22 [PMID: 29941298] (Bioassay, Human)	Bioassay	Human
J Li, F Xing, F Chen, L He, KF So, Y Liu, J Xiao Functional 3D Human Liver Bud Assembled from MSC-Derived Multiple Liver Cell Lineages Cell Transplant, 2018-06-13;0(0):9636897187803. 2018-06-13 [PMID: 29895168] (Bioassay, Human)	Bioassay	Human
K Skrzypek, A Kusienicka, E Trzyna, B Szewczyk, A Ulman, P Konieczny, T Adamus, B Badyra, M Kortylewsk, M Majka SNAIL is a key regulator of alveolar rhabdomyosarcoma tumor growth and differentiation through repression of MYF5 and MYOD function Cell Death Dis, 2018-05-29;9(6):643. 2018-05-29 [PMID: 29844345] (Bioassay, Human)	Bioassay	Human
H Yang, C Wang, H Chen, L Li, S Ma, H Wang, Y Fu, T Qu Neural Stem Cell-Conditioned Medium Ameliorated Cerebral Ischemia-Reperfusion Injury in Rats Stem Cells Int, 2018-04-03;2018(0):4659159. 2018-04-03 [PMID: 29765412] (Bioassay, Rat)	Bioassay	Rat
X Guo, Y Xu, Z Wang, Y Wu, J Chen, G Wang, C Lu, W Jia, J Xi, S Zhu, Z Jiapaer, X Wan, Z Liu, S Gao, J Kang A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis Cell Stem Cell, 2018-05-10;0(0):. 2018-05-10 [PMID: 29754779] (Bioassay, Mouse)	Bioassay	Mouse
B Roy, S Venkatacha, P Ratna, Y Wang, DS Jokhun, M Nagarajan, GV Shivashank Laterally confined growth of cells induces nuclear reprogramming in the absence of exogenous biochemical factors Proc. Natl. Acad. Sci. U.S.A., 2018-05-07;0(0):. 2018-05-07 [PMID: 29735717] (Bioassay, Human)	Bioassay	Human
LR Penke, JM Speth, VL Dommeti, ES White, IL Bergin, M Peters-Gol FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis J. Clin. Invest., 2018-05-07;0(0):. 2018-05-07 [PMID: 29733296] (Bioassay, Human)	Bioassay	Human
IG Ryoo, BH Choi, SK Ku, MK Kwak High CD44 expression mediates p62-associated NFE2L2/NRF2 activation in breast cancer stem cell-like cells: Implications for cancer stem cell resistance Redox Biol, 2018-04-26;17(0):246-258. 2018-04-26 [PMID: 29729523] (Bioassay, Human)	Bioassay	Human
M Li, D Khong, LY Chin, A Singleton, B Parekkadan Therapeutic Delivery Specifications Identified Through Compartmental Analysis of a Mesenchymal Stromal Cell-Immune Reaction Sci Rep, 2018-05-01;8(1):6816. 2018-05-01 [PMID: 29717209] (Bioassay, Human)	Bioassay	Human
M Zaim, S Isik DNA topoisomerase II? stimulates neurite outgrowth in neural differentiated human mesenchymal stem cells through regulation of Rho-GTPases (RhoA/Rock2 pathway) and Nurr1 expression Stem Cell Res Ther, 2018-04-25;9(1):114. 2018-04-25 [PMID: 29695291] (Bioassay, Human)	Bioassay	Human
F Ihler, R Gratz, HA Wolff, BG Weiss, M Bertlich, J Kitz, G Salinas, M Rave-Fränk, M Canis Epithelial-Mesenchymal Transition during Metastasis of HPV-Negative Pharyngeal Squamous Cell Carcinoma Biomed Res Int, 2018-03-06;2018(0):7929104. 2018-03-06 [PMID: 29693014] (Bioassay, Human)	Bioassay	Human
JE Shin, K Jung, M Kim, K Hwang, H Lee, IS Kim, BH Lee, IS Lee, KI Park Brain and spinal cord injury repair by implantation of human neural progenitor cells seeded onto polymer scaffolds Exp. Mol. Med., 2018-04-20;50(4):39. 2018-04-20 [PMID: 29674624] (Bioassay, Human)	Bioassay	Human
JX Liu, D Bravo, J Buza, T Kirsch, O Kennedy, A Rokito, JD Zuckerman, MS Virk Topical vancomycin and its effect on survival and migration of osteoblasts, fibroblasts, and myoblasts: An in vitro study J Orthop, 2018-01-30;15(1):53-58. 2018-01-30 [PMID: 29657439] (Bioassay, Human)	Bioassay	Human
V Pursani, D Bhartiya, V Tanavde, M Bashir, P Sampath Transcriptional activator DOT1L putatively regulates human embryonic stem cell differentiation into the cardiac lineage Stem Cell Res Ther, 2018-04-10;9(1):97. 2018-04-10 [PMID: 29631608] (Bioassay, Human)	Bioassay	Human
N Guzzi, M Cie?la, PCT Ngoc, S Lang, S Arora, M Dimitriou, K Pimková, MNE Sommarin, R Munita, M Lubas, Y Lim, K Okuyama, S Soneji, G Karlsson, J Hansson, G Jönsson, AH Lund, M Sigvardsso, E Hellström-, AC Hsieh, C Bellodi Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells Cell, 2018-04-05;0(0):. 2018-04-05 [PMID: 29628141] (Bioassay, Human)	Bioassay	Human
SM Planchon, KT Lingas, J Reese Koç, BM Hooper, B Maitra, RM Fox, PB Imrey, KM Drake, MA Aldred, HM Lazarus, JA Cohen Feasibility of mesenchymal stem cell culture expansion for a phase I clinical trial in multiple sclerosis Mult Scler J Exp Transl Clin, 2018-03-26;4(1):2055217318765. 2018-03-26 [PMID: 29623216] (Bioassay, Human)	Bioassay	Human
M Kim, K Jung, IS Kim, IS Lee, Y Ko, JE Shin, KI Park TNF-? induces human neural progenitor cell survival after oxygen-glucose deprivation by activating the NF-?B pathway Exp. Mol. Med., 2018-04-06;50(4):14. 2018-04-06 [PMID: 29622770] (Bioassay, Human)	Bioassay	Human
D Poppe, J Doerr, M Schneider, R Wilkens, JA Steinbeck, J Ladewig, A Tam, DE Paschon, PD Gregory, A Reik, CE Müller, P Koch, O Brüstle Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity Stem Cells Transl Med, 2018-03-28;0(0):. 2018-03-28 [PMID: 29589874] (Bioassay, Human)	Bioassay	Human
J Ou, JM Ball, Y Luan, T Zhao, KJ Miyagishim, Y Xu, H Zhou, J Chen, DK Merriman, Z Xie, BS Mallon, W Li iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications Cell, 2018-03-22;0(0):. 2018-03-22 [PMID: 29576452] (Bioassay, Squirrel)	Bioassay	Squirrel
FN Vögtle, B Brändl, A Larson, M Pendziwiat, MW Friederich, SM White, A Basinger, C Kücükköse, H Muhle, JA Jähn, O Keminer, KL Helbig, CF Delto, L Myketin, D Mossmann, N Burger, N Miyake, A Burnett, A van Baalen, MA Lovell, N Matsumoto, M Walsh, HC Yu, DN Shinde, U Stephani, JLK Van Hove, FJ Müller, I Helbig Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood Am. J. Hum. Genet., 2018-03-22;0(0):. 2018-03-22 [PMID: 29576218] (Bioassay, Human)	Bioassay	Human
S Gillotin, JD Davies, A Philpott Subcellular localisation modulates ubiquitylation and degradation of Ascl1 Sci Rep, 2018-03-15;8(1):4625. 2018-03-15 [PMID: 29545540] (Bioassay, Human)	Bioassay	Human
M Zhang, J Ngo, F Pirozzi, YP Sun, A Wynshaw-Bo Highly efficient methods to obtain homogeneous dorsal neural progenitor cells from human and mouse embryonic stem cells and induced pluripotent stem cells Stem Cell Res Ther, 2018-03-15;9(1):67. 2018-03-15 [PMID: 29544541] (Bioassay, Human)	Bioassay	Human
C Zarouchlio, B Sanchez-Pi, NJ Hafford Te, P Klein, P Liskova, K Dulla, M Semo, AA Vugler, K Muthusamy, L Dudakova, HJ Levis, P Skalicka, P Hysi, ME Cheetham, SJ Tuft, P Adamson, AJ Hardcastle, AE Davidson Antisense Therapy for a Common Corneal Dystrophy Ameliorates TCF4 Repeat Expansion-Mediated Toxicity Am. J. Hum. Genet., 2018-03-08;0(0):. 2018-03-08 [PMID: 29526280] (Bioassay, Human)	Bioassay	Human
R Tang, L Jing, VP Willard, CL Wu, F Guilak, J Chen, LA Setton Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells Stem Cell Res Ther, 2018-03-09;9(1):61. 2018-03-09 [PMID: 29523190] (Bioassay, Human)	Bioassay	Human
EM André, N Daviaud, L Sindji, J Cayon, R Perrot, CN Montero-Me A novel ex vivo Huntington's disease model for studying GABAergic neurons and cell grafts by laser microdissection PLoS ONE, 2018-03-05;13(3):e0193409. 2018-03-05 [PMID: 29505597] (Bioassay, Human)	Bioassay	Human
G Zhao, CG Bailey, Y Feng, J Rasko, FJ Lovicu Negative regulation of lens fiber cell differentiation by RTK antagonists Spry and Spred Exp. Eye Res., 2018-03-01;170(0):148-159. 2018-03-01 [PMID: 29501879] (Bioassay, Rat)	Bioassay	Rat
W Wang, D Chen, K Zhu SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition J. Exp. Clin. Cancer Res., 2018-02-23;37(1):37. 2018-02-23 [PMID: 29475441] (Bioassay, Human)	Bioassay	Human
YG Kim, YN Yoon, HS Choi, JH Kim, H Seol, JK Lee, MK Seong, IC Park, KI Kim, HA Kim, JS Kim, WC Noh Breast cancer stem cells in HER2-negative breast cancer cells contribute to HER2-mediated radioresistance and molecular subtype conversion: clinical implications for serum HER2 in recurrent HER2-negative breast cancer Oncotarget, 2017-12-20;9(5):5811-5822. 2017-12-20 [PMID: 29464036] (Bioassay, Human)	Bioassay	Human
ME Katt, RM Linville, LN Mayo, ZS Xu, PC Searson Functional brain-specific microvessels from iPSC-derived human brain microvascular endothelial cells: the role of matrix composition on monolayer formation Fluids Barriers CNS, 2018-02-20;15(1):7. 2018-02-20 [PMID: 29463314] (Bioassay, Human)	Bioassay	Human
EJ Ostrin, DR Little, KN Gerner-Mau, EA Sumner, R Ríos-Corzo, E Ambrosio, SE Holt, NR Forcioli-C, H Akiyama, SM Hanash, S Kimura, SXL Huang, J Chen Beta-Catenin maintains lung epithelial progenitors after lung specification Development, 2018-03-09;0(0):. 2018-03-09 [PMID: 29440304] (Bioassay, Human)	Bioassay	Human
T Speck, JP Heidbueche, R Veinalde, D Jaeger, C von Kalle, CR Ball, G Ungerechts, CE Engeland Targeted BiTE expression by an oncolytic vector augments therapeutic efficacy against solid tumors Clin. Cancer Res., 2018-02-06;0(0):. 2018-02-06 [PMID: 29437789] (Bioassay, Human)	Bioassay	Human
A Wahba, MC Ryan, UT Shankavara, K Camphausen, PJ Tofilon Radiation-induced alternative transcripts as detected in total and polysome-bound mRNA Oncotarget, 2017-10-09;9(1):691-705. 2017-10-09 [PMID: 29416646] (Bioassay, Human)	Bioassay	Human
C Laterza, N Uoshima, D Tornero, U Wilhelmsso, A Stokowska, R Ge, M Pekny, O Lindvall, Z Kokaia Attenuation of reactive gliosis in stroke-injured mouse brain does not affect neurogenesis from grafted human iPSC-derived neural progenitors PLoS ONE, 2018-02-05;13(2):e0192118. 2018-02-05 [PMID: 29401502] (Bioassay, Human)	Bioassay	Human
G Zhou, H Jiang, Z Yin, Y Liu, Q Zhang, C Zhang, B Pan, J Zhou, X Zhou, H Sun, D Li, A He, Z Zhang, W Zhang, W Liu, Y Cao In Vitro Regeneration of Patient-specific Ear-shaped Cartilage and Its First Clinical Application for Auricular Reconstruction EBioMedicine, 2018-01-13;28(0):287-302. 2018-01-13 [PMID: 29396297] (Bioassay, Human)	Bioassay	Human
J Catry, M Luong-Nguy, L Arakelian, T Poghosyan, P Bruneval, T Domet, L Michaud, R Sfeir, F Gottrand, J Larghero, V Vanneaux, P Cattan Circumferential Esophageal Replacement by a Tissue-engineered Substitute Using Mesenchymal Stem Cells: An Experimental Study in Mini Pigs Cell Transplant, 2017-12-01;26(12):1831-1839. 2017-12-01 [PMID: 29390879] (Bioassay, Porcine)	Bioassay	Porcine
M Stromecki, N Tatari, LC Morrison, R Kaur, J Zagozewski, G Palidwor, V Ramaswamy, P Skowron, M Wölfl, T Milde, MR Del Bigio, MD Taylor, TE Werbowetsk Characterization of a novel OTX2-driven stem cell program in Group 3 and Group 4 medulloblastoma Mol Oncol, 2018-03-01;12(4):495-513. 2018-03-01 [PMID: 29377567] (Bioassay, Human)	Bioassay	Human
S Miyamoto, V Kochin, T Kanaseki, A Hongo, S Tokita, Y Kikuchi, A Takaya, Y Hirohashi, T Tsukahara, T Terui, K Ishitani, F Hata, I Takemasa, A Miyazaki, H Hiratsuka, N Sato, T Torigoe The antigen ASB4 on cancer stem cells serves as a target for CTL immunotherapy of colorectal cancer Cancer Immunol Res, 2018-01-25;0(0):. 2018-01-25 [PMID: 29371260] (Bioassay, Human)	Bioassay	Human
N Dreyer-And, AS Almeida, P Jensen, M Kamand, J Okarmus, T Rosenberg, SD Friis, A Martínez S, M Blaabjerg, BW Kristensen, T Skrydstrup, JB Gramsberge, HLA Vieira, M Meyer Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells PLoS ONE, 2018-01-16;13(1):e0191207. 2018-01-16 [PMID: 29338033] (Bioassay, Human)	Bioassay	Human
V Sobrino, P González-R, V Annese, J López-Barn, R Pardal Fast neurogenesis from carotid body quiescent neuroblasts accelerates adaptation to hypoxia EMBO Rep., 2018-01-15;0(0):. 2018-01-15 [PMID: 29335248] (Cell Culture, Human)	Cell Culture	Human
G Detela, OW Bain, HW Kim, DJ Williams, C Mason, A Mathur, IB Wall Donor variability in growth kinetics of healthy hMSCs using manual processing: considerations for manufacture of cell therapies Biotechnol J, 2018-01-25;0(0):. 2018-01-25 [PMID: 29334181] (Bioassay, Human)	Bioassay	Human
CL Duran, CA Abbey, KJ Bayless Establishment of a three-dimensional model to study human uterine angiogenesis Mol. Hum. Reprod., 2018-02-01;0(0):. 2018-02-01 [PMID: 29329415] (Bioassay, Human)	Bioassay	Human
JJ Gell, J Zhao, D Chen, TJ Hunt, AT Clark PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation Stem Cell Res, 2018-01-04;27(0):46-56. 2018-01-04 [PMID: 29324254] (Bioassay, Human)	Bioassay	Human
CJ Drummond, JA Hanna, MR Garcia, DJ Devine, AJ Heyrana, D Finkelstei, JE Rehg, ME Hatley Hedgehog Pathway Drives Fusion-Negative Rhabdomyosarcoma Initiated From Non-myogenic Endothelial Progenitors Cancer Cell, 2018-01-08;33(1):108-124.e5. 2018-01-08 [PMID: 29316425] (Bioassay, Mouse)	Bioassay	Mouse
VT Cheriyan, HO Alsaab, S Sekhar, C Stieber, P Kesharwani, S Sau, M Muthu, LA Polin, E Levi, AK Iyer, AK Rishi A CARP-1 functional mimetic loaded vitamin E-TPGS micellar nano-formulation for inhibition of renal cell carcinoma Oncotarget, 2017-09-05;8(62):104928-104945. 2017-09-05 [PMID: 29285223] (Bioassay)	Bioassay
JJ Song, SM Oh, OC Kwon, N Wulnansari, HS Lee, MY Chang, E Lee, W Sun, SE Lee, S Chang, H An, CJ Lee, SH Lee Cografting astrocytes improves cell therapeutic outcomes in a Parkinson's disease model J. Clin. Invest., 2017-12-11;0(0):. 2017-12-11 [PMID: 29227284] (Bioassay, Mouse, Rat)	Bioassay	Mouse, Rat
J Dietrich, N Baryawno, N Nayyar, YK Valtis, B Yang, I Ly, A Besnard, N Severe, KU Gustafsson, OC Andronesi, TT Batchelor, A Sahay, DT Scadden Bone marrow drives central nervous system regeneration after radiation injury J. Clin. Invest., 2017-12-04;0(0):. 2017-12-04 [PMID: 29202481] (Bioassay, Mouse)	Bioassay	Mouse
T Johansen, C Krabbe, SI Schmidt, AM Serrano, M Meyer Comparative Analysis of Spontaneous and Stimulus-Evoked Calcium Transients in Proliferating and Differentiating Human Midbrain-Derived Stem Cells Stem Cells Int, 2017-10-22;2017(0):9605432. 2017-10-22 [PMID: 29201062] (Bioassay, Human)	Bioassay	Human
SD Muthukrish, S Ryzhov, M Karolak, L Oxburgh Nephron progenitor cell death elicits a limited compensatory response associated with interstitial expansion in the neonatal kidney Dis Model Mech, 2018-01-29;0(0):. 2018-01-29 [PMID: 29196442] (Bioassay, Mouse)	Bioassay	Mouse
L Todd, L Suarez, C Quinn, AJ Fischer Retinoic Acid-Signaling Regulates the Proliferative and Neurogenic Capacity of Mï¿½ller Glia-Derived Progenitor Cells in the Avian Retina Stem Cells, 2017-11-27;0(0):. 2017-11-27 [PMID: 29193451] (In Vivo, Chicken)	In Vivo	Chicken
A Taguchi, R Nishinakam Higher-Order Kidney Organogenesis from Pluripotent Stem Cells Cell Stem Cell, 2017-11-09;0(0):. 2017-11-09 [PMID: 29129523] (Differentiation, Differentiation, Human)	Differentiation, Differentiation	Human
HM Lee, JW Joh, SR Seo, WT Kim, MK Kim, HS Choi, SY Kim, YJ Jang, DH Sinn, GS Choi, JM Kim, CHD Kwon, HJ Chang, DS Kim, CJ Ryu Cell-surface major vault protein promotes cancer progression through harboring mesenchymal and intermediate circulating tumor cells in hepatocellular carcinomas Sci Rep, 2017-10-16;7(1):13201. 2017-10-16 [PMID: 29038587] (Bioassay, Human)	Bioassay	Human
M Bhogal, CN Lwin, XY Seah, E Murugan, K Adnan, SJ Lin, G Peh, JS Mehta Real-time assessment of corneal endothelial cell damage following graft preparation and donor insertion for DMEK PLoS ONE, 2017-10-04;12(10):e0184824. 2017-10-04 [PMID: 28977017] (Bioassay, Human)	Bioassay	Human
F Wang, AY Wang, C Chesnelong, Y Yang, A Nabbi, S Thalappill, V Alekseev, K Riabowol ING5 activity in self-renewal of glioblastoma stem cells via calcium and follicle stimulating hormone pathways Oncogene, 2017-09-18;37(3):286-301. 2017-09-18 [PMID: 28925404] (Bioassay, Human)	Bioassay	Human
J Xing, Y Cao, Y Yu, H Li, Z Song, H Yu In Vitro Micropatterned Human Pluripotent Stem Cell Test (ï¿½P-hPST) for Morphometric-Based Teratogen Screening Sci Rep, 2017-08-17;7(1):8491. 2017-08-17 [PMID: 28819231] (Bioassay, Human)	Bioassay	Human
JH Lee, SI Protze, Z Laksman, PH Backx, GM Keller Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations Cell Stem Cell, 2017-08-03;21(2):179-194.e4. 2017-08-03 [PMID: 28777944] (Bioassay, Human)	Bioassay	Human
S Mahati, D Bolati, Y Yang, R Mao, H Zhang, Y Bao TMPRSS4 promotes cancer stem cell traits by regulating CLDN1 in hepatocellular carcinoma Biochem. Biophys. Res. Commun., 2017-06-23;0(0):. 2017-06-23 [PMID: 28651932] (Bioassay, Human)	Bioassay	Human
J Kuusela, K Larsson, D Shah, C Prajapati, K Aalto-Setä Low extracellular potassium prolongs repolarization and evokes early afterdepolarization in human induced pluripotent stem cell-derived cardiomyocytes Biol Open, 2017-06-15;6(6):777-784. 2017-06-15 [PMID: 28619993] (Bioassay, Human)	Bioassay	Human
A De Pauw, E Andre, B Sekkali, C Bouzin, H Esfahani, N Barbier, A Loriot, C De Smet, L Vanhoutte, S Moniotte, B Gerber, V di Mauro, D Catalucci, O Feron, D Hilfiker-K, JL Balligand Dnmt3a-mediated inhibition of Wnt in cardiac progenitor cells improves differentiation and remote remodeling after infarction JCI Insight, 2017-06-15;2(12):. 2017-06-15 [PMID: 28614798] (Bioassay, Mouse)	Bioassay	Mouse
RO Pereira, SM Tadinada, FM Zasadny, KJ Oliveira, KMP Pires, A Olvera, J Jeffers, R Souvenir, R Mcglauflin, A Seei, T Funari, H Sesaki, MJ Potthoff, CM Adams, EJ Anderson, ED Abel OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance EMBO J., 2017-06-12;0(0):. 2017-06-12 [PMID: 28607005] (Bioassay, Human)	Bioassay	Human
KG Wong, SD Ryan, K Ramnarine, SA Rosen, SE Mann, A Kulick, E De Stanchi, FJ Müller, TJ Kacmarczyk, C Zhang, D Betel, MJ Tomishima CryoPause: A New Method to Immediately Initiate Experiments after Cryopreservation of Pluripotent Stem Cells Stem Cell Reports, 2017-06-08;0(0):. 2017-06-08 [PMID: 28602613] (Bioassay, Human)	Bioassay	Human
A Prieur, M Cappellini, G Habif, MP Lefranc, T Mazard, E Morency, JM Pascussi, M Flaceliere, N Cahuzac, B Vire, B Dubuc, A Durochat, P Liaud, J Ollier, C Pfeiffer, S Poupeau, V Saywell, C Planque, E Assenat, F Bibeau, JF Bourgaux, P Pujol, A Sézeur, M Ychou, D Joubert Targeting the Wnt pathway and cancer stem cells with anti-progastrin humanized antibodies: a major breakthrough for K-RAS mutated colorectal cancer treatment Clin. Cancer Res., 2017-06-09;0(0):. 2017-06-09 [PMID: 28600477] (Bioassay, Human)	Bioassay	Human
N Rahman, PM Brauer, L Ho, T Usenko, M Tewary, JC Zúñiga-Pfl, PW Zandstra Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence Nat Commun, 2017-05-25;8(0):15380. 2017-05-25 [PMID: 28541275] (Bioassay, Human)	Bioassay	Human
JR Chao, DA Lamba, TR Klesert, A Torre, A Hoshino, RJ Taylor, A Jayabalu, AL Engel, TH Khuu, RK Wang, M Neitz, J Neitz, TA Reh Transplantation of Human Embryonic Stem Cell-Derived Retinal Cells into the Subretinal Space of a Non-Human Primate Transl Vis Sci Technol, 2017-05-16;6(3):4. 2017-05-16 [PMID: 28516002] (Bioassay, Human)	Bioassay	Human
JK Hu, W Du, SJ Shelton, MC Oldham, CM DiPersio, OD Klein An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice Cell Stem Cell, 2017-04-27;0(0):. 2017-04-27 [PMID: 28457749] (Bioassay, Mouse)	Bioassay	Mouse
DJ Tischfield, J Kim, SA Anderson Atypical PKC and Notch Inhibition Differentially Modulate Cortical Interneuron Subclass Fate from Embryonic Stem Cells Stem Cell Reports, 2017-04-13;0(0):. 2017-04-13 [PMID: 28416285] (Bioassay, Mouse)	Bioassay	Mouse
H Zhang, F Sun, J Wang, L Xie, C Yang, M Pan, B Shao, GY Yang, SH Yang, Q ZhuGe, K Jin Combining Injectable Plasma Scaffold with Mesenchymal Stem/Stromal Cells for Repairing Infarct Cavity after Ischemic Stroke Aging Dis, 2017-04-01;8(2):203-214. 2017-04-01 [PMID: 28400986] (Bioassay, Human)	Bioassay	Human
R Allison, JR Edgar, G Pearson, T Rizo, T Newton, S Günther, F Berner, J Hague, JW Connell, J Winkler, J Lippincott, C Beetz, B Winner, E Reid Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia J. Cell Biol., 2017-04-07;0(0):. 2017-04-07 [PMID: 28389476] (Bioassay, Human)	Bioassay	Human
EE Pashos, Y Park, X Wang, A Raghavan, W Yang, D Abbey, DT Peters, J Arbelaez, M Hernandez, N Kuperwasse, W Li, Z Lian, Y Liu, W Lv, SL Lytle-Gabb, DH Marchadier, P Rogov, J Shi, KJ Slovik, IM Stylianou, L Wang, R Yan, X Zhang, S Kathiresan, SA Duncan, TS Mikkelsen, EE Morrisey, DJ Rader, CD Brown, K Musunuru Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci Cell Stem Cell, 2017-04-06;20(4):558-570.e10. 2017-04-06 [PMID: 28388432] (Bioassay, Human)	Bioassay	Human
F Chen, Y Ni, B Liu, T Zhou, C Yu, Y Su, X Zhu, X Yu, Y Zhou Self-crosslinking and injectable hyaluronic acid/RGD-functionalized pectin hydrogel for cartilage tissue engineering Carbohydr Polym, 2017-02-20;166(0):31-44. 2017-02-20 [PMID: 28385238] (Bioassay, Porcine)	Bioassay	Porcine
Y Pan, LJ Smithson, Y Ma, D Hambardzum, DH Gutmann Ccl5 establishes an autocrine high-grade glioma growth regulatory circuit critical for mesenchymal glioblastoma survival Oncotarget, 2017-05-16;0(0):. 2017-05-16 [PMID: 28380429] (Bioassay, Mouse)	Bioassay	Mouse
LA Ahrens, D Vonwil, J Christense, VP Shastri Gelatin device for the delivery of growth factors involved in endochondral ossification PLoS ONE, 2017-04-05;12(4):e0175095. 2017-04-05 [PMID: 28380024] (Bioassay, Chicken, Human)	Bioassay	Chicken, Human
KB McCauley, F Hawkins, M Serra, DC Thomas, A Jacob, DN Kotton Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling Cell Stem Cell, 2017-03-30;0(0):. 2017-03-30 [PMID: 28366587] (Bioassay, Human, Mouse)	Bioassay	Human, Mouse
NA Guadagno, C Moriconi, V Licursi, E D'Acunto, PS Nisi, N Carucci, A De Jaco, E Cacci, R Negri, G Lupo, E Miranda Neuroserpin polymers cause oxidative stress in a neuronal model of the dementia FENIB Neurobiol. Dis., 2017-03-28;103(0):32-44. 2017-03-28 [PMID: 28363799] (Bioassay, Human)	Bioassay	Human
DC Thomas, S Clare, JM Sowerby, M Pardo, JK Juss, DA Goulding, L van der We, D Storistean, A Prakash, M Espéli, S Flint, JC Lee, K Hoenderdos, L Kane, K Harcourt, S Mukhopadhy, Y Umrania, R Antrobus, JA Nathan, DJ Adams, A Bateman, JS Choudhary, PA Lyons, AM Condliffe, ER Chilvers, G Dougan, KG Smith Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity J. Exp. Med, 2017-03-28;0(0):. 2017-03-28 [PMID: 28351984] (Bioassay, Human)	Bioassay	Human
PH Vincent, E Benedikz, P Uhlen, O Hovatta, E Sundström Expression of Pluripotency Markers in Non-pluripotent Human Neural Stem and Progenitor Cells Stem Cells Dev., 2017-03-27;0(0):. 2017-03-27 [PMID: 28351210] (Bioassay, Human)	Bioassay	Human
F Sampazioti, MC de Brito, I Geti, A Bertero, NR Hannan, L Vallier Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells Nat Protoc, 2017-03-23;12(4):814-827. 2017-03-23 [PMID: 28333915] (Bioassay, Human)	Bioassay	Human
K Eun, HM Jeon, SO Kim, SH Choi, SY Lee, X Jin, SC Kim, H Kim A cell-autonomous positive-signaling circuit associated with the PDGF-NO-ID4-regulatory axis in glioblastoma cells Biochem. Biophys. Res. Commun, 2017-03-19;0(0):. 2017-03-19 [PMID: 28327358] (Bioassay, Human)	Bioassay	Human
AR Bonilla-Po, C Velez-Pard, M Jimenez-De Fast transdifferentiation of human Wharton's jelly mesenchymal stem cells into neurospheres and nerve-like cells J. Neurosci. Methods, 2017-03-08;0(0):. 2017-03-08 [PMID: 28286110] (Bioassay, Human)	Bioassay	Human
D Chen, M Wu, Y Li, I Chang, Q Yuan, M Ekimyan-Sa, P Deng, B Yu, Y Yu, J Dong, JM Szymanski, S Ramadoss, J Li, CY Wang Targeting BMI1(+) Cancer Stem Cells Overcomes Chemoresistance and Inhibits Metastases in Squamous Cell Carcinoma Cell Stem Cell, 2017-03-09;0(0):. 2017-03-09 [PMID: 28285905] (Bioassay, Human)	Bioassay	Human
I Rudnik-Jan, S Colen, J Berard, S Plomp, I Que, M van Rijen, N Woike, A Egas, G van Osch, E van Maarse, K Messier, A Chan, J Thies, L Creemers Prolonged inhibition of inflammation in osteoarthritis by triamcinolone acetonide released from a polyester amide microsphere platform J Control Release, 2017-03-09;0(0):. 2017-03-09 [PMID: 28284832] (Bioassay, Human)	Bioassay	Human
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Inagaki A, Soeda A, Oka N, Kitajima H, Nakagawa J, Motohashi T, Kunisada T, Iwama T Long-term maintenance of brain tumor stem cell properties under at non-adherent and adherent culture conditions. Biochem. Biophys. Res. Commun., 2007-07-18;361(3):586-92. 2007-07-18 [PMID: 17673180] (Bioassay, Human)	Bioassay	Human
Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature, 2007-06-27;448(7150):196-9. 2007-06-27 [PMID: 17597760] (Bioassay, Human, Mouse)	Bioassay	Human, Mouse
Vallier L, Alexander M, Pedersen R Conditional gene expression in human embryonic stem cells. Stem Cells, 2007-02-22;25(6):1490-7. 2007-02-22 [PMID: 17322103] (Bioassay, Human)	Bioassay	Human
Salero E, Hatten ME Differentiation of ES cells into cerebellar neurons. Proc. Natl. Acad. Sci. U.S.A., 2007-02-09;104(8):2997-3002. 2007-02-09 [PMID: 17293457] (Bioassay, Mouse)	Bioassay	Mouse
Rajesh</LastName><ForeNam D</Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells, 2007-02-01;25(2):490-9. 2007-02-01 [PMID: 17284653] (Bioassay, Human, Mouse)	Bioassay	Human, Mouse
Josephson R, Ording CJ, Liu Y, Shin S, Lakshmipathy U, Toumadje A, Love B, Chesnut JD, Andrews PW, Rao MS, Auerbach JM Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell research. Stem Cells, 2007-02-01;25(2):437-46. 2007-02-01 [PMID: 17284651] (Bioassay, Human)	Bioassay	Human
Williamson D, Selfe J, Lu YJ, Pritchard-Jones K, Murai K, Jones P, Workman P, Shipley J Role for amplification and expression of glypican-5 in rhabdomyosarcoma. Cancer Res., 2007-01-01;67(1):57-65. 2007-01-01 [PMID: 17210683] (Bioassay, Human, Xenopus)	Bioassay	Human, Xenopus
McLean AB, D&apos;Amour KA, Jones KL, Krishnamoorthy M, Kulik MJ, Reynolds DM, Sheppard AM, Liu H, Xu Y, Baetge EE, Dalton S Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed. Stem Cells, 2007-01-01;25(1):29-38. 2007-01-01 [PMID: 17204604] (Bioassay, Human)	Bioassay	Human
Nakayama T, Mutsuga N, Tosato G FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc. Blood, 2006-10-31;109(4):1363-72. 2006-10-31 [PMID: 17077327] (Bioassay, Mouse)	Bioassay	Mouse
Bartunek J, Croissant JD, Wijns W, Gofflot S, de Lavareille A, Vanderheyden M, Kaluzhny Y, Mazouz N, Willemsen P, Penicka M, Mathieu M, Homsy C, De Bruyne B, McEntee K, Lee IW, Heyndrickx GR Pretreatment of adult bone marrow mesenchymal stem cells with cardiomyogenic growth factors and repair of the chronically infarcted myocardium. Am. J. Physiol. Heart Circ. Physiol., 2006-10-20;292(2):H1095-104. 2006-10-20 [PMID: 17056665] (Bioassay, Canine, Human)	Bioassay	Canine, Human
Porat Y, Porozov S, Belkin D, Shimoni D, Fisher Y, Belleli A, Czeiger D, Silverman WF, Belkin M, Battler A, Fulga V, Savion N Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages. Br. J. Haematol., 2006-12-01;135(5):703-14. 2006-12-01 [PMID: 17052254] (Bioassay, Human)	Bioassay	Human
Benzing C, Segschneider M, Leinhaas A, Itskovitz-Eldor J, Brustle O Neural conversion of human embryonic stem cell colonies in the presence of fibroblast growth factor-2. Neuroreport, 2006-11-06;17(16):1675-81. 2006-11-06 [PMID: 17047452] (Bioassay, Human)	Bioassay	Human
Greber B, Lehrach H, Adjaye J Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal. Stem Cells, 2006-10-12;25(2):455-64. 2006-10-12 [PMID: 17038665] (Bioassay, Human)	Bioassay	Human
Lake AC, Vassy R, Di Benedetto M, Lavigne D, Le Visage C, Perret GY, Letourneur D Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1. J. Biol. Chem., 2006-10-06;281(49):37844-52. 2006-10-06 [PMID: 17028197] (Bioassay, Human)	Bioassay	Human
Aghajanova L, Skottman H, Stromberg AM, Inzunza J, Lahesmaa R, Hovatta O Expression of leukemia inhibitory factor and its receptors is increased during differentiation of human embryonic stem cells. Fertil. Steril., 2006-09-01;86(4):1193-209. 2006-09-01 [PMID: 16949591] (Bioassay, Human)	Bioassay	Human
Lindsley RC, Gill JG, Kyba M, Murphy TL, Murphy KM Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development, 2006-08-30;133(19):3787-96. 2006-08-30 [PMID: 16943279] (Bioassay, Mouse)	Bioassay	Mouse
Zeng L, Rahrmann E, Hu Q, Lund T, Sandquist L, Felten M, O'Brien TD, O'Brien TD, Zhang J, Verfaillie C Multipotent adult progenitor cells from swine bone marrow. Stem Cells, 2006-08-24;24(11):2355-66. 2006-08-24 [PMID: 16931778] (Bioassay, Porcine)	Bioassay	Porcine
Kobayashi T, Ahlenius H, Thored P, Kobayashi R, Kokaia Z, Lindvall O Intracerebral infusion of glial cell line-derived neurotrophic factor promotes striatal neurogenesis after stroke in adult rats. Stroke, 2006-07-27;37(9):2361-7. 2006-07-27 [PMID: 16873711] (Bioassay, Rat)	Bioassay	Rat
Yamashita H, Nakamura T, Takahashi T, Nagano Y, Hiji M, Hirabayashi T, Amano T, Yagi T, Sakai N, Kohriyama T, Matsumoto M Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death. J. Neurochem., 2006-07-01;98(1):45-56. 2006-07-01 [PMID: 16805795] (Bioassay, Mouse)	Bioassay	Mouse
Murata T, Tsuboi M, Hikita K, Kaneda N Protective effects of neurotrophic factors on tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis of murine adrenal chromaffin cell line tsAM5D. J. Biol. Chem., 2006-06-13;281(32):22503-16. 2006-06-13 [PMID: 16772303] (Bioassay, Mouse)	Bioassay	Mouse
Kurita R, Sasaki E, Yokoo T, Hiroyama T, Takasugi K, Imoto H, Izawa K, Dong Y, Hashiguchi T, Soda Y, Maeda T, Suehiro Y, Tanioka Y, Nakazaki Y, Tani K Tal1/Scl gene transduction using a lentiviral vector stimulates highly efficient hematopoietic cell differentiation from common marmoset (Callithrix jacchus) embryonic stem cells. Stem Cells, 2006-05-25;24(9):2014-22. 2006-05-25 [PMID: 16728561] (Bioassay, Primate - Callitrix jacchus (Common Marmoset))	Bioassay	Primate - Callitrix jacchus (Common Marmoset)
Yu H, Fang D, Kumar SM, Li L, Nguyen TK, Acs G, Herlyn M, Xu X Isolation of a novel population of multipotent adult stem cells from human hair follicles. Am. J. Pathol., 2006-06-01;168(6):1879-88. 2006-06-01 [PMID: 16723703] (Bioassay, Human)	Bioassay	Human
Li Y, Fan J, Chen M, Li W, Woodley DT Transforming growth factor-alpha: a major human serum factor that promotes human keratinocyte migration. J. Invest. Dermatol., 2006-05-11;126(9):2096-105. 2006-05-11 [PMID: 16691197] (Bioassay, Human)	Bioassay	Human
Moreno MJ, Ball M, Andrade MF, McDermid A, Stanimirovic DB Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells. Glia, 2006-06-01;53(8):845-57. 2006-06-01 [PMID: 16586492] (Bioassay, Human)	Bioassay	Human
Lee YS, Lin CY, Robertson RT, Yu J, Deng X, Hsiao I, Lin VW Re-growth of catecholaminergic fibers and protection of cholinergic spinal cord neurons in spinal repaired rats. Eur. J. Neurosci., 2006-02-01;23(3):693-702. 2006-02-01 [PMID: 16487151] (In Vivo, Rat)	In Vivo	Rat
Anghelina M, Krishnan P, Moldovan L, Moldovan NI Monocytes/macrophages cooperate with progenitor cells during neovascularization and tissue repair: conversion of cell columns into fibrovascular bundles. Am. J. Pathol., 2006-02-01;168(2):529-41. 2006-02-01 [PMID: 16436667] (In Vivo, Mouse)	In Vivo	Mouse
Narazaki M, Tosato G Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A. Blood, 2006-01-19;107(10):3892-901. 2006-01-19 [PMID: 16424390] (ELISA (Standard))	ELISA (Standard)
Faraone D, Aguzzi MS, Ragone G, Russo K, Capogrossi MC, Facchiano A Heterodimerization of FGF-receptor 1 and PDGF-receptor-alpha: a novel mechanism underlying the inhibitory effect of PDGF-BB on FGF-2 in human cells. Blood, 2005-12-01;107(5):1896-902. 2005-12-01 [PMID: 16322476] (Bioassay, Human)	Bioassay	Human
Tsai MS, Hwang SM, Tsai YL, Cheng FC, Lee JL, Chang YJ Clonal amniotic fluid-derived stem cells express characteristics of both mesenchymal and neural stem cells. Biol. Reprod., 2005-11-23;74(3):545-51. 2005-11-23 [PMID: 16306422] (Bioassay, Human)	Bioassay	Human
Shin JW, Min M, Larrieu-Lahargue F, Canron X, Kunstfeld R, Nguyen L, Henderson JE, Bikfalvi A, Detmar M, Hong YK Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis. Mol. Biol. Cell, 2005-11-16;17(2):576-84. 2005-11-16 [PMID: 16291864] (Bioassay, Human)	Bioassay	Human
Bagley RG, Weber W, Rouleau C, Teicher BA Pericytes and endothelial precursor cells: cellular interactions and contributions to malignancy. Cancer Res., 2005-11-01;65(21):9741-50. 2005-11-01 [PMID: 16266995] (Bioassay, Human)	Bioassay	Human
Kim B, Lee S, Suvas S, Rouse BT Application of plasmid DNA encoding IL-18 diminishes development of herpetic stromal keratitis by antiangiogenic effects. J. Immunol., 2005-07-01;175(1):509-16. 2005-07-01 [PMID: 15972686] (Bioassay, Mouse)	Bioassay	Mouse
Schmidt-Ott KM, Yang J, Chen X, Wang H, Paragas N, Mori K, Li JY, Lu B, Costantini F, Schiffer M, Bottinger E, Barasch J Novel regulators of kidney development from the tips of the ureteric bud. J. Am. Soc. Nephrol., 2005-05-25;16(7):1993-2002. 2005-05-25 [PMID: 15917337] (Bioassay, Rat)	Bioassay	Rat
Fischer AJ, Omar G Transitin, a nestin-related intermediate filament, is expressed by neural progenitors and can be induced in Muller glia in the chicken retina. J. Comp. Neurol., 2005-03-28;484(1):1-14. 2005-03-28 [PMID: 15717308] (In Vivo, Chicken)	In Vivo	Chicken
Steinberg Z, Myers C, Heim VM, Lathrop CA, Rebustini IT, Stewart JS, Larsen M, Hoffman MP FGFR2b signaling regulates ex vivo submandibular gland epithelial cell proliferation and branching morphogenesis. Development, 2005-02-16;132(6):1223-34. 2005-02-16 [PMID: 15716343] (Bioassay, Mouse)	Bioassay	Mouse
Fischer AJ, Omar G, Eubanks J, McGuire CR, Dierks BD, Reh TA Different aspects of gliosis in retinal Muller glia can be induced by CNTF, insulin, and FGF2 in the absence of damage. Mol. Vis., 2004-12-22;10(0):973-86. 2004-12-22 [PMID: 15623987] (In Vivo, Chicken)	In Vivo	Chicken
Nagineni CN, Kutty V, Detrick B, Hooks JJ Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta. J. Cell. Physiol., 2005-04-01;203(1):35-43. 2005-04-01 [PMID: 15368539] (Bioassay, Human)	Bioassay	Human
Ni HT, Hu S, Sheng WS, Olson JM, Cheeran MC, Chan AS, Lokensgard JR, Peterson PK High-level expression of functional chemokine receptor CXCR4 on human neural precursor cells. Brain Res. Dev. Brain Res., 2004-09-17;152(2):159-69. 2004-09-17 [PMID: 15351504] (Bioassay, Human)	Bioassay	Human
Tardif G, Hum D, Pelletier JP, Boileau C, Ranger P, Martel-Pelletier J Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts. Arthritis Rheum., 2004-08-01;50(8):2521-30. 2004-08-01 [PMID: 15334466] (Bioassay, Human)	Bioassay	Human
Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments. Blood, 2004-03-25;104(2):314-20. 2004-03-25 [PMID: 15044249] (Bioassay, Human)	Bioassay	Human
Sharma MR, Tuszynski GP, Sharma MC Angiostatin-induced inhibition of endothelial cell proliferation/apoptosis is associated with the down-regulation of cell cycle regulatory protein cdk5. J. Cell. Biochem., 2004-02-01;91(2):398-409. 2004-02-01 [PMID: 14743398] (Bioassay, Bovine)	Bioassay	Bovine
Wang J, Roy SK Growth differentiation factor-9 and stem cell factor promote primordial follicle formation in the hamster: modulation by follicle-stimulating hormone. Biol. Reprod., 2003-10-29;70(3):577-85. 2003-10-29 [PMID: 14585807] (Bioassay, Hamster)	Bioassay	Hamster
Yi M, Sakai T, Fassler R, Ruoslahti E Antiangiogenic proteins require plasma fibronectin or vitronectin for in vivo activity. Proc. Natl. Acad. Sci. U.S.A., 2003-09-17;100(20):11435-8. 2003-09-17 [PMID: 13679585] (In Vivo, Mouse)	In Vivo	Mouse
Kovalenko D, Yang X, Nadeau RJ, Harkins LK, Friesel R Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation. J. Biol. Chem., 2003-02-24;278(16):14087-91. 2003-02-24 [PMID: 12604616] (Bioassay, Human, Mouse, Primate - Chlorocebus pygerythrus (Vervet Monkey))	Bioassay	Human, Mouse, Primate - Chlorocebus pygerythrus (Vervet Monkey)
Barbour AP, Reeder JA, Walsh MD, Fawcett J, Antalis TM, Gotley DC Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3. Cancer Res., 2003-02-15;63(4):887-92. 2003-02-15 [PMID: 12591743] (Binding Assay, Human)	Binding Assay	Human
Bandyopadhyay A, 2019, Zhu Y, Malik SN, Kreisberg J, Brattain MG, Sprague EA, Luo J, Lopez-Casillas F, Sun LZ Extracellular domain of TGFbeta type III receptor inhibits angiogenesis and tumor growth in human cancer cells. 101205, 2002-05-16;21(22):3541-51. 2002-05-16 [PMID: 12032856] (In Vivo, Mouse)	In Vivo	Mouse
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FAQs for FGF basic/FGF2/bFGF (233-FB). (Showing 1 - 1 of 1 FAQs).

I am looking for an ovine antibody for bFGF and PDGF-AB and ELISA Kits for both. It is for a research work on meniscus healing in sheep. Do you have anything suitable? How is the homology with sheep? Is it ever tested and/or published in papers?
- Unfortunately, most of the products you are interested in have not yet been tested in sheep, but this should not be a problem, due to sequence homology, and our Innovators Reward Program. In terms of an antibody for bFGF, also called FGF-2, we have several antibodies that are validated to detect the bovine protein, which is almost identical to that from sheep (99% homology). We only have FGF2 ELISA kits that have been tested with human or mouse. Mouse FGF-2 has 94% homology with sheep; human has 98% homology for most of its sequence, but also has an additional stretch of amino acids that is not present in the sheep protein. I therefore think that the mouse kit would be most suitable, just in case the human kit targets the region of the human protein not present in mouse. We sell antibodies to PDGF-A or PDGF-B rather than PDGF-AB. We don't have any PDGF-A antibodies that have been tested in sheep but there are several options you may find of interest. There isn't a sheep PDGFA sequence in UniProt, so I can't comment on how similar it is to the PDGFA from other species. Nevertheless, our NBP1-52533 PDGFB antibody has been shown to work in sheep. We sell two PDGF-AB ELISA kits , but these are for human and rat. I'm not sure how well these would work with sheep. Note that if you test a product with a species (or application) that it has not yet been validated in, you are eligible for our Innovator's Reward: Novus would provide you a 50% refund on the purchased product as well as a 50% discount on a future product of equal or lesser value. You would email innovators@novusbio.com to apply for your award, and we

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Gene Symbol	FGF2
Uniprot	P09038()

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Recombinant Human FGF basic/FGF2/bFGF (146 aa) Protein

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