Sin1/MAPKAP1 Antibody (752219)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

MAPKAP1 (mitogen-activated protein kinase (MAPK) associated protein-1), also called Mip1 (MAPK interacting protein 1) or Sin1 (stress-activated protein kinase (SAPK) interacting 1), is a widely expressed 59-65 kDa cytoplasmic phosphoprotein. MAPKAP1 binds to inactive forms of signaling molecules such as MEKK2 and Ras. Alternate mRNA splicing potentially creates isoforms of 323, 330, 372, 475, 486 and 522 amino acids (aa) in humans. The human MAPKAP1 region used as an immunogen is included in all except the smallest isoform, and shares 96% aa sequence identity with mouse and rat MAPKAP1.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using MAB8168	Applications	Species
Cameron AJM, Veeriah S, Marshall JJT et al. Uncoupling TORC2 from AGC kinases inhibits tumour growth Oncotarget. 2017-10-17 [PMID: 29156676]

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: Verified Customer	WB	Mouse	10/23/2019	View Summary Application Western Blot Sample Tested Adipose tissue Species Mouse Lot CGFJ011909A Comments Comments Mouse white adipose tissue was homogenised and protein content was quantified by a BCA assay. Twenty micrograms of protein were resolved on a 4-12% Bis-Tris gel and transferred to nitrocellulose membranes. Membranes were probed with primary antibody MAPKAP1 diluted 1:1000 in 5% BSA 2, before incubation with anti mouse secondary horseradish peroxidase-conjugated antibody 1:5000. Blots were visualised with Immobilon Western Chemiluminescence HRP Substrate and imaged with Syngene chemiluminescence imaging system.

Array MAB8168

• Sin1/MAPKAP1 Antibodies
• Sin1/MAPKAP1 Lysates
• Sin1/MAPKAP1 Proteins