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SETDB1 Antibody [DyLight 650]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 650

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SETDB1 Antibody [DyLight 650] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residues 1125 and 1175 of human SET Domain, Bifurcated 1 using the numbering given in entry NP_036564.2 (GeneID 9869).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SETDB1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SETDB1 Antibody [DyLight 650]

  • ERG-associated protein with SET domain
  • ESETEC 2.1.1.43
  • H3-K9-HMTase 4
  • Histone H3-K9 methyltransferase 4
  • histone-lysine N-methyltransferase SETDB1
  • histone-lysine N-methyltransferase, H3lysine-9 specific 4
  • KG1T
  • KIAA0067H3-K9-HMTase4
  • KMT1EERG-associated protein with a SET domain, ESET
  • Lysine N-methyltransferase 1E
  • SET domain bifurcated 1
  • SET domain, bifurcated 1

Background

The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and 039;Enhancer of zeste 039 proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities. [supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SETDB1