E. coli-derived recombinant human Serpin F1, Mouse myeloma cell line NS0-derived recombinant human Serpin F1, and S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Serpin F1 Asp44-Pro418 Accession # P36955
Specificity
Detects human Serpin F1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse Serpin F1 is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
SERPINF1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Serpin F1/PEDF Antibody (187003)
Cell proliferation-inducing gene 35 protein
EPC-1
EPC-1PIG35
PEDF
PEDFpigment epithelium-derived factor
pigment epithelium derived factor), member 1
proliferation-inducing protein 35
serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin
Serpin F1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epitheliumderived factor), member 1
Background
Serpin F1, also known as pigment epithelium derived factor (PEDF), is a
secreted glycoprotein that shows sequence and structural similarity
with the serpin superfamily proteins, but lacks serine protease
inhibitory activity. Serpin F1 has been shown to have cell-type
specific functions including inhibition of retinal angiogenesis and
neurotrophic activity in the retina and central nervous system.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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