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SCP3/SYCP3 Antibody

Images

 
Immunohistochemistry-Paraffin: SCP3/SYCP3 Antibody [NBP2-54713] - Staining of human testis shows high expression.
Immunohistochemistry-Paraffin: SCP3/SYCP3 Antibody [NBP2-54713] - Staining of human endometrium shows low expression as expected.
Orthogonal Strategies: Immunohistochemistry-Paraffin: SCP3/SYCP3 Antibody [NBP2-54713] - Staining in human testis and endometrium tissues using anti-SYCP3 antibody. Corresponding SYCP3 RNA-seq data are presented ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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SCP3/SYCP3 Antibody Summary

Immunogen
This antibody was developed against a Recombinant Protein corresponding to amino acids: KYSRKSGKPSVEDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSAGVVEDMGGEVQNMLEGV
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SYCP3
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
SCP3/SYCP3 Recombinant Protein Antigen (NBP2-54713PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SCP3/SYCP3 Antibody

  • COR1
  • MGC71888
  • SCP3 chromosome 3 open reading frame 8
  • SCP3 COR1
  • SCP3
  • SCP-3
  • SYCP3
  • synaptonemal complex protein 3

Background

SCP3 is a major component of the transverse filaments of the synaptonemal complexes that mediate synapses during the zygotene stage. SCP-3 is formed between homologus chromosomes during meiotic prophase, and plays an essential role in the meiotic function of spermatogenesis. Therefore, this protein is necessary for proper testis development and defects in the SYCP3 gene can lead to azoospermia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Blogs on SCP3/SYCP3.

SCP3: A Key to Meiotic Recombination, Sterility and Cancer
Synaptonemal Complex Protein 3 (SCP3), which is a protein present in the synaptonemal complex which is responsible for pairing, synapsis, and recombination of homologous chromosomes during meiosis. Meiosis, in basic terms, is where germ cells divide t...  Read full blog post.

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Bioinformatics

Gene Symbol SYCP3