Quantikine Immunoassay Control Set 398 for Human BLC/BCA-1 Summary
Additional Information |
For use with catalog number DCX130 |
Source |
N/A |
Inter-Assay |
See PDF Datasheet for details |
Intra-Assay |
See PDF Datasheet for details |
Spike Recovery |
See PDF Datasheet for details |
Sample Volume |
See PDF Datasheet for details |
Gene |
CXCL13 |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Quantikine Immunoassay Control Set 398 for Human BLC/BCA-1
Background
CXCL13/BLC/BCA-1 is a constitutively expressed chemokine that plays an important role in B and T cell homing. It is expressed by salivary gland epithelium, dendritic cells, osteoclasts, and peritoneal macrophages. It can form homodimers or heterodimers with FGF basic, and it signals through CXCR3 or CXCR5. CXCL13 induces the migration of naïve B cells and a subset of memory T cells to lymphoid tissue. It also promotes B1 cell migration into the omentum and peritoneum. In the fetus, CXCL13 attracts CD4+ CD3- IL-7 R alpha+ hematopoietic cells to sites of future Peyer’s patch development.
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