PADI4 Antibody - BSA Free

Protein-arginine deiminase type-4 (PAD4) is a member of the protein arginine deiminase family (also known as peptidylarginine deiminase IV, PAD, PDI4, PDI5, and PADI5). Enzymes in the protein arginine deiminase family catalyze the conversion of arginine residues into citrulline residues. More specifically, PAD4 converts arginine residues to citrulline at Arg-8 and Arg-17 on histone H3 and Arg-3 on histone H4, thus preventing methylation at these sites by CARM1 and HRMT1L2/PRMT1. PAD4 also induces a favorable interaction between EP300/P300 and NCOA2/GRIP1 by citrullinating EP300/P300 at Arg-2142. In addition, the PAD4 enzyme may also be involved in the development of granulocytes and macrophages. PAD4 is expressed in the cytoplasmic granules of eosinophils and neutrophils, and is not expressed in peripheral monocytes or lymphocytes. Areas of interest involving PAD4 research include inflammation, immune response, and rheumatoid arthritis.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array NBP1-97309

• PADI4 Antibodies
• PADI4 ELISA Kits
• PADI4 Lysate
• PADI4 Proteins
• PADI4 Proteins and Enzyme