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Nurr1/NGFI-B beta/NR4A2 Antibody (HL1852) - Azide and BSA Free

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Immunocytochemistry/Immunofluorescence: Nurr1/NGFI-B beta/NR4A2 Antibody (HL1852) - Azide and BSA Free [NBP3-25582] - Nurr1 antibody [HL1852] detects Nurr1 protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Nurr1 stained by Nurr1 antibody [HL1852] (NBP3-25582) diluted at 1:500. Blue: Fluoroshield with DAPI .
Immunocytochemistry/ Immunofluorescence: Nurr1/NGFI-B beta/NR4A2 Antibody (HL1852) - Azide and BSA Free [NBP3-25582] - Nurr1 antibody [HL1852] detects Nurr1 protein at cytoplasm and nucleus by immunofluorescent ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clone
HL1852
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free

Order Details

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Nurr1/NGFI-B beta/NR4A2 Antibody (HL1852) - Azide and BSA Free Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant fragment of human Nurr1/NGFI-B beta/NR4A2
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
NR4A2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A purified

Alternate Names for Nurr1/NGFI-B beta/NR4A2 Antibody (HL1852) - Azide and BSA Free

  • human homolog of
  • NGFI-B beta
  • NOT
  • NR4A2
  • nuclear receptor subfamily 4, group A, member 2
  • Nurr1
  • orphan nuclear receptor NR4A2
  • Orphan nuclear receptor NURR1
  • T-cell nuclear receptor NOT
  • TINUR
  • transcriptionally inducible nuclear receptor related 1
  • Transcriptionally-inducible nuclear receptor

Background

The Nurr1 gene encodes a member of the steroid-thyroid hormone- retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's. Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of murine and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype. In addition, Nurr1 is involved in the regulation of corticotropin-releasing hormone (CRH), which may be linked to and associated with rheumatoid arthritis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NR4A2