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N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody

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Western Blot: N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody [H00002588-B01P] - Analysis of GALNS expression in transfected 293T cell line by GALNS polyclonal antibody. Lane1:GALNS transfected lysate(57.42 KDa). Lane2:Non-transfected lysate.
Western Blot: N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody [H00002588-B01P] - Analysis of GALNS expression in transfected 293T cell line by GALNS polyclonal antibody. Lane1:GALNS transfected lysate(57.42 KDa). ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

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N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody Summary

Description
Quality control test: Antibody reactive against mammalian transfected lysate.
Immunogen
GALNS (NP_000503.1, 1 a.a. - 522 a.a.) full-length human protein. MAAVVAATRWWQLLLVLSAAGMGASGAPQPPNILLLLMDDMGWGDLGVYGEPSRETPNLDRMAAEGLLFPNFYSANPLCSPSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLGHRPQFHPLKHGFDEWFGSPNCHFGPYDNKARPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYASKPFLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGDTLMAATLGQHKAHFWTWTNSWENFRQGIDFCPGQNVSGVTTHNLEDHTKLPLIFHLGRDPGERFPLSFASAEYQEALSRITSVVQQHQEALVPAQPQLNVCNWAVMNWAPPGCEKLGKCLTPPESIPKKCLWSH
Specificity
GALNS - galactosamine (N-acetyl)-6-sulfate sulfatase (Morquio syndrome, mucopolysaccharidosis type IVA),
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
GALNS
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for N-Acetylgalactosamine-6-Sulfatase/GALNS Antibody

  • Chondroitinase
  • Chondroitinsulfatase
  • EC 3.1.6
  • EC 3.1.6.4
  • FLJ17434
  • FLJ42844
  • FLJ98217
  • GA6S
  • galactosamine (N-acetyl)-6-sulfate sulfatase
  • Galactose-6-Sulfate Sulfatase
  • GalNAc6S Sulfatase
  • GALNAC6S
  • GALNS
  • GAS
  • MPS4A
  • NAcetylgalactosamine6Sulfatase
  • N-Acetylgalactosamine-6-Sulfatase
  • N-acetylgalactosamine-6-sulfate sulfatase

Background

This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GALNS
Entrez
Uniprot