MYCBP2 Antibody (PSH03-68) Summary
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
Recombinant protein within human MYCBP2 aa 1-300. (Uniprot: O75592) |
Localization |
Nucleus, Cell projection, axon, Cytoplasm, cytoskeleton. |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
MYCBP2 |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 1:1000
- Immunocytochemistry/ Immunofluorescence 1:100
- Immunohistochemistry
- Immunohistochemistry-Paraffin 1:500
- Western Blot 1:2000
|
Theoretical MW |
514 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS (pH7.4), 0.1% BSA and 40% Glycerol |
Preservative |
0.05% Sodium Azide |
Concentration |
1 mg/ml |
Purity |
Protein A purified |
Alternate Names for MYCBP2 Antibody (PSH03-68)
Background
In addition to its possible functions as a facilitator of Myc activated transcription, PAM (protein associated with Myc) has also been shown to play a role in mTOR signaling. PAM functions as an E3 ubiquitin ligase for tuberin (TSC2), a negative regulator of the mTOR pathway. Additionally PAM has been shown to function as a guanosine exchange factor (GEF) for Rheb and to facilitate sphingosine-1-phosphate signaling in the mTOR pathway. Alternative names for PAM include Myc-binding protein 2, MYCBP2, Pam/highwire/rpm-1 protein, and KIAA0916.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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