Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu, Mu
Applications: WB, IP (-)
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Description
In addition to its possible functions as a facilitator of Myc activated transcription, PAM (protein associated with Myc) has also been shown to play a role in mTOR signaling. PAM functions as an E3 ubiquitin ligase for tuberin (TSC2), a negative regulator of the mTOR pathway. Additionally PAM has been shown to function as a guanosine exchange factor (GEF) for Rheb and to facilitate sphingosine-1-phosphate signaling in the mTOR pathway. Alternative names for PAM include Myc-binding protein 2, MYCBP2, Pam/highwire/rpm-1 protein, and KIAA0916.
Bioinformatics
| Uniprot |
Human
|
| Product By Gene ID |
23077 |
| Alternate Names |
- DKFZp686M08244
- EC 6.3.2.-
- FLJ10106
- FLJ21646
- KIAA0916FLJ13826
- MYC binding protein 2
- Myc-binding protein 2
- Pam/highwire/rpm-1 protein
- PAMFLJ21597
- probable E3 ubiquitin-protein ligase MYCBP2
- Protein associated with Myc
|
