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Latent TGF-beta bp2/LTBP-2 Recombinant Protein Antigen

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Summary
Reactivity HuSpecies Glossary
Applications AC

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Latent TGF-beta bp2/LTBP-2 Recombinant Protein Antigen Summary

Description
A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human LTBP2.

Source: E. coli

Amino Acid Sequence: ERSPNLRRSSAAGEGTLARAQPPAPQSPPAPQSPPAGTLSGLSQTHPSQQHVGLSRTVRLHPTATASSQLSSNALPPGPGLEQRDGTQQAVPLEHPSSPWGLNLTEKIKKIKIVFTPTICKQTCARGHCANSCERG

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.
Source
E. coli
Protein/Peptide Type
Recombinant Protein Antigen
Gene
LTBP2
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Dilutions
  • Antibody Competition 10 - 100 molar excess
Application Notes
This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP1-88411.It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com
Theoretical MW
32 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 1M Urea, pH 7.4.
Preservative
No Preservative
Purity
>80% by SDS-PAGE and Coomassie blue staining

Alternate Names for Latent TGF-beta bp2/LTBP-2 Recombinant Protein Antigen

  • C14orf141
  • GLC3D
  • Latent TGFbeta bp2
  • Latent TGF-beta bp2
  • latent transforming growth factor beta binding protein 2
  • latent-transforming growth factor beta-binding protein 2
  • LTBP2
  • LTBP-2
  • LTBP3chromosome 14 open reading frame 141
  • MSTP031

Background

LTBP2, also known as latent-transforming growth factor beta-binding protein 2, is a 195 kDa, 1,821 amino acid protein that is involved in assembly and organization of cellular structure as a member of the latent transforming growth factor=beta binding protein (LTBP) family. Current research is being conducted to study the effect of the protein on diseases and disorders such as fibrosis, primary congenital glaucoma type 3D, carcinoma, hepatitis, melanoma, corneal edema, Weill-Marchesani Syndrome, and pancreatitis. The protein interacts in elastic fiber formation, paxillin interaction, mitochondrial apoptosis, extracellular matrix organization, and molecular mechanisms of cancer pathways with other proteins including FYN, FBLN5, and ABL1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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NBP1-88411PEP
Latent TGF-beta bp2/LTBP-2 Recombinant Protein Antigen
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Bioinformatics

Gene Symbol LTBP2