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Integrin alpha L/CD11a Antibody (MEM-25) [DyLight 680]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IP, CyTOF-ready
Clone
MEM-25
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB500-328AF350
Alexa Fluor 405
NB500-328AF405
Alexa Fluor 488
NB500-328AF488
Alexa Fluor 532
NB500-328AF532
Alexa Fluor 594
NB500-328AF594
Alexa Fluor 647
NB500-328AF647
Alexa Fluor 700
NB500-328AF700
Alexa Fluor 750
NB500-328AF750
Allophycocyanin
NB500-328APC
Allophycocyanin/Cy7
NB500-328APCCY7
Biotin
NB110-81625
CoraFluor 1
NB500-328CL1
DyLight 350
NB500-328UV
DyLight 405
NB500-328V
DyLight 594
NB500-328DL594
DyLight 755
NB500-328IR
FITC
NB500-328F
Janelia Fluor 525
NB500-328JF525
Janelia Fluor 549
NB500-328JF549
Janelia Fluor 585
NB500-328JF585
Janelia Fluor 635
NB500-328JF635
Janelia Fluor 646
NB500-328JF646
Janelia Fluor 669
NB500-328JF669
PE
NB500-328PE
PE/Atto594
NB500-328PEATT594
PE/Cy5.5
NB500-328PECY55
PE/Cy7
NB500-328PECY7
PerCP
NB500-328PCP
Unconjugated
NB500-328
mFluor Violet 450 SE
NB500-328MFV450
mFluor Violet 500 SE
NB500-328MFV500
mFluor Violet 610 SE
NB500-328MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB500-328
Low Endotoxin, Azide and BSA Free
NBP2-37712
BSA Free
NB500-328
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Integrin alpha L/CD11a Antibody (MEM-25) [DyLight 680] Summary

Additional Information
Clone MEM-25 was used by HLDA to establish CD designation.
Immunogen
Leucocytes from a patient suffering from a LGL-type leukemia (NM_001114380.1).
Specificity
The antibody MEM-25 reacts with CD11a (alpha subunit of human LFA-1), a 170-180 kDa type I transmembrane glycoprotein expressed on B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. HLDA IV; WS Code NL 209
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ITGAL
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Integrin alpha L/CD11a Antibody (MEM-25) [DyLight 680]

  • CD11 antigen-like family member A
  • CD11a antigen
  • CD11a
  • CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide
  • Integrin alpha L
  • integrin alpha-L
  • integrin gene promoter
  • integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide)
  • ITGAL
  • Leukocyte adhesion glycoprotein LFA-1 alpha chain
  • Leukocyte function-associated molecule 1 alpha chain
  • LFA-1 alpha
  • LFA-1
  • LFA1A
  • LFA-1A
  • Ly-15
  • Ly-21
  • lymphocyte function-associated antigen 1

Background

CD11a is a member of the integrin family of cell adhesion molecules. It is a glycoprotein expressed in combination with the CD18 beta chain. CD11a is a member of the beta 2 integrin family. These molecules function in cell adhesion and specifically bind to CD54, ICAM2, ICAM3. CD11a is expressed on thymocytes, T and B lymphocytes, granulocytes, monocytes, and macrophages.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Integrin alpha
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NB500-328FR
Integrin alpha L/CD11a Antibody (MEM-25) [DyLight 680]
Species: Hu
Applications: Flow, IP, CyTOF-ready

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Bioinformatics

Gene Symbol ITGAL