4% PFA fixed and paraffin embedded mouse spleen tissue section was subjected to IHC staining of mouse CD11c. The antigen retrieval recommended for this antibody is the treatment with 20ug/ml Proteinase K in PBS for 15-25 minutes at room temperature. This antibody is CyTOF ready. Use in ICC/IF reported in scientific literature (PMID: 30300579). Use in Immunohistochemistry-Frozen reported in scientific literature (PMID:31138656).
Publications
Read Publications using NB110-97871 in the following applications:
Human reactivity reported in scientific literature (PMID: 30455684).
Packaging, Storage & Formulations
Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Lyophilized from a 0.2 um filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified
Reconstitution Instructions
Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.
Alternate Names for CD11c Antibody (AP-MAB0806) - Azide and BSA Free
95 alpha chain
95
95, alpha subunit
CD11 antigen-like family member C
CD11c antigen
CD11c
CD11Cleu M5, alpha subunit
Integrin alpha X
integrin alpha-X
integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
integrin, alpha X (complement component 3 receptor 4 subunit)
ITGAX
Leu M5
Leukocyte adhesion glycoprotein p150
Leukocyte adhesion receptor p150
leukocyte surface antigen p150
myeloid membrane antigen, alpha subunit
p150 95 integrin alpha chain
p150,95 alpha
SLEB6
Background
CD11c (integrin alpha X chain protein) combines with the beta 2 chain (ITGB2) to form a leukocyte specific integrin referred to as inactivated C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. The CD11c antigen is a marker for hairy cell leukemia.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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