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Integrin alpha 6/CD49f Antibody (MP4F10)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IP, CyTOF-ready
Clone
MP4F10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1350U-100UG
Alexa Fluor 405
FAB1350V-100UG
Alexa Fluor 488
FAB1350G-100UG
Alexa Fluor 532
FAB1350X
Alexa Fluor 594
FAB1350T-100UG
Alexa Fluor 647
FAB1350R-100UG
Alexa Fluor 700
FAB1350N-100UG
Alexa Fluor 750
FAB1350S-100UG
Allophycocyanin
FAB1350A
Allophycocyanin/Cy7
FAB1350APCCY7
Biotin
FAB1350B
DyLight 350
FAB1350D
DyLight 405
FAB1350E
DyLight 488
FAB1350K
DyLight 550
FAB1350L
DyLight 594
FAB1350M
DyLight 650
FAB1350W
DyLight 680
FAB1350Y
DyLight 755
FAB1350Z
FITC
FAB1350F
HRP
FAB1350H
Janelia Fluor 525
FAB1350JF525
Janelia Fluor 549
FAB1350I
Janelia Fluor 585
FAB1350JF585
Janelia Fluor 635
FAB1350JF635
Janelia Fluor 646
FAB1350J
Janelia Fluor 669
FAB1350JF669
PE
FAB1350P
PE/Atto594
FAB1350PEATT594
PE/Cy5.5
FAB1350PECY55
PE/Cy7
FAB1350PECY7
PerCP
FAB1350C
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB1350-SP
Carrier Free
FAB1350V-100UG
Carrier Free
FAB1350U-100UG
Carrier Free
FAB1350T-100UG
Carrier Free
FAB1350S-100UG
Carrier Free
FAB1350R-100UG
Carrier Free
FAB1350N-100UG
Carrier Free
FAB1350G-100UG
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Integrin alpha 6/CD49f Antibody (MP4F10) Summary

Immunogen
SW1222 human colorectal carcinoma cell line
Specificity
Detects human Integrin  alpha 6/CD49f.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
ITGA6
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
  • Immunohistochemistry 8-25 ug/mL
  • Immunoprecipitation
Publications
Read Publications using
MAB1350 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Integrin alpha 6/CD49f Antibody (MP4F10)

  • CD49 antigen-like family member F
  • CD49f antigen
  • CD49f
  • DKFZp686J01244
  • FLJ18737
  • Integrin alpha 6
  • integrin alpha-6
  • integrin alpha6B
  • integrin, alpha 6
  • ITGA6
  • ITGA6B
  • Platelet gpl
  • VLA-6

Background

The Integrin alpha 6 subunit, also known as CD49f and VLA-6 alpha subunit, forms a heterodimer with Integrin beta 1 (CD29) or beta 4 (CD104) subunits. Integrin alpha 6 beta 1 is a receptor for laminin. Integrin alpha 6 beta 4 is also a receptor for laminin and is a structural component of hemidesmosomes in stratified epithelia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Integrin alpha 6/CD49f Antibody (MAB1350)(6)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: ELISA Detection, Flow Cytometry, ICC.


Filter By Application
ELISA Detection
(1)
Flow Cytometry
(1)
ICC
(2)
All Applications
Filter By Species
Human
(4)
All Species
Showing Publications 1 - 6 of 6.
Publications using MAB1350 Applications Species
Sally Dabelsteen, Emil M.H. Pallesen, Irina N. Marinova, Mathias I. Nielsen, Maria Adamopoulou, Troels B. Rømer et al. Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model Developmental Cell 9/14/2020 [PMID: 32710848]
R Giampieri, F Piva, G Occhipinti, A Bittoni, A Righetti, S Pagliarett, A Murrone, F Bianchi, C Amantini, M Giulietti, G Ricci, G Principato, G Santoni, R Berardi, S Cascinu Clinical impact of different exosomes' protein expression in pancreatic ductal carcinoma patients treated with standard first line palliative chemotherapy PLoS ONE, 2019-05-02;14(5):e0215990. 2019-05-02 [PMID: 31048929] (ELISA Detection, Human) ELISA Detection Human
Hoque , Md Tamji, Windus , Louisa C, Lovitt , Carrie J, Avery , Vicky M PCaAnalyser: a 2D-image analysis based module for effective determination of prostate cancer progression in 3D culture. PLoS ONE, 2013-11-20;8(11):e79865. 2013-11-20 [PMID: 24278197] (ICC, Human) ICC Human
Malgorzata Czyz, Kamila Koprowska, Malgorzata Sztiller-Sikorska Parthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres Cancer Biology & Therapy 2/1/2013 [PMID: 23192276]
Mierke CT, Frey B, Fellner M, Herrmann M, Fabry B Integrin alpha5beta1 facilitates cancer cell invasion through enhanced contractile forces. J. Cell. Sci., 2011-01-11;124(0):369-83. 2011-01-11 [PMID: 21224397] (Flow Cytometry, Human) Flow Cytometry Human
Corneal epithelial cell adhesion and growth on EGF-modified aminated PDMS. J Biomed Mater Res A, 2010-06-01;93(3):1043-9. 2010-06-01 [PMID: 19753622] (ICC, Human) ICC Human

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Bioinformatics

Gene Symbol ITGA6