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IL-17/IL-17A Antibody (41802) [Allophycocyanin]

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Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with PMA and Calcium Ionomycin were stained with Mouse Anti-Human IL-17/IL-17A APC-conjugated Monoclonal Antibody (Catalog # IC3171A) ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
41802
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

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IL-17/IL-17A Antibody (41802) [Allophycocyanin] Summary

Immunogen
E. coli-derived recombinant human IL-17
Ile20-Ala155
Accession # Q16552
Specificity
Detects human IL-17 in direct ELISAs. In direct ELISAs, approximately 40% cross-reactivity with recombinant human (rh) IL-17A/IL-17F heterodimer is observed. No cross-reactivity with recombinant mouse IL-17, recombinant canine Il-17, rhIL-17B, rhIL-17C, rhIL-17D, rhIL-17E, or rhIL-17F is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IL17A
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
IC3171A in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IL-17/IL-17A Antibody (41802) [Allophycocyanin]

  • CTLA8
  • CTLA-8
  • CTLA8cytotoxic T-lymphocyte-associated serine esterase 8
  • Cytotoxic T-lymphocyte-associated antigen 8
  • IL17
  • IL-17
  • IL17A
  • IL-17A
  • IL-17Acytotoxic T-lymphocyte-associated protein 8
  • IL-17CTLA-8
  • IL17interleukin-17A
  • interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
  • interleukin 17A

Background

Interleukin-17 (IL-17) is a pro-inflammatory cytokine secreted by activated T cells. It is the prototype member of the IL-17 family that also includes IL-17B, C, D, E, and F.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for IL-17/IL-17A Antibody (IC3171A)(5)

We have publications tested in 2 confirmed species: Human, Primate - Macaca mulatta (Rhesus Macaque).

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(5)
All Applications
Filter By Species
Human
(4)
Primate - Macaca mulatta (Rhesus Macaque)
(1)
All Species
Showing Publications 1 - 5 of 5.
Publications using IC3171A Applications Species
M Lobna, E Nasren, S Adi, B Jacob, GA Maria, M Marcus, V Zahava The Expression of IL-17, in Chronic Spontaneous Urticaria Is Linked to Semaphorin5A Biomolecules, 2021-03-02;11(3):. 2021-03-02 [PMID: 33801296] (Flow Cytometry, Human) Flow Cytometry Human
DJ Dowling, SD van Haren, A Scheid, I Bergelson, D Kim, CJ Mancuso, W Foppen, A Ozonoff, L Fresh, TB Theriot, AA Lackner, RN Fichorova, D Smirnov, JP Vasilakos, JM Beaurline, MA Tomai, CC Midkiff, X Alvarez, JL Blanchard, MH Gilbert, PP Aye, O Levy TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth JCI Insight, 2017-03-23;2(6):e91020. 2017-03-23 [PMID: 28352660] (Flow Cytometry, Primate - Macaca mulatta (Rhesus Macaque)) Flow Cytometry Primate - Macaca mulatta (Rhesus Macaque)
Ofer Levy Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization J. Immunol., 2016-10-28;0(0):. 2016-10-28 [PMID: 27793997] (Flow Cytometry, Human) Flow Cytometry Human
Wongkajornsilp A, Wamanuttajinda V, Kasetsinsombat K, Duangsa-ard S, Sa-ngiamsuntorn K, Hongeng S, Maneechotesuwan K Sunitinib indirectly enhanced anti-tumor cytotoxicity of cytokine-induced killer cells and CD3(+)CD56(+) subset through the co-culturing dendritic cells. PLoS ONE, 2013-11-13;8(11):e78980. 2013-11-13 [PMID: 24232460] (Flow Cytometry, Human) Flow Cytometry Human
Yang L, Anderson DE, Baecher-Allan C, Hastings WD, Bettelli E, Oukka M, Kuchroo VK, Hafler DA IL-21 and TGF-beta are required for differentiation of human T(H)17 cells. Nature, 2008-05-11;454(7202):350-2. 2008-05-11 [PMID: 18469800] (Flow Cytometry, Human) Flow Cytometry Human

Reviews for IL-17/IL-17A Antibody (IC3171A) (0)

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FAQs for IL-17/IL-17A Antibody (IC3171A). (Showing 1 - 2 of 2 FAQs).

  1. I want to stain some T cell subsets (Th17 and Th1), do you have antibodies for that? I need for flow cytometer in sheep or goat.
    • Unfortunately, we have neither a CD4 antibody nor an IL-17 antibody that has been validated in sheep or goat, although if you would like to try one you would again be eligible for our Innovators Reward Program. Please contact us at innovators@novusbio.com with any questions regarding this program.
  2. I'm looking to establish an ELISA for IL-17 and want your recommendation on which antibody pairs to buy. Least expensive ones, please. Also, I'd like the detection antibody to be fluorescently labeled.
    • Thank you for your patience while I reviewed our ELISA validated products for IL17. I was not sure what species you were going to be investigating, so I looked up our data for the human protein. If this is incorrect, just let me know and I can look up products for the species you will be working with. As for antibody pairs, we only had one set that have been tested together: Capture: NBP2-22531 Detection: NBP2-22532. The detection product is only available currently with a biotin conjugate. We can however offer custom conjugation for this product to any of our available conjugates. Please see the this link to see the available fluors. The typical fee for custom conjugation is usually about $80 additional. Once you know which fluor you would like, I can provide you with a quote. We do also offer several ELISA kits for this target (they typically employ HRP or Biotin detection systems, so I am not sure if they will work for your needs).
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Bioinformatics

Gene Symbol IL17A
Uniprot