Home » IL-17/IL-17A » IL-17/IL-17A Antibodies » IL-17/IL-17A Antibody (41802) [Janelia Fluor® 646]
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IL-17/IL-17A Antibody (41802) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP, CyTOF-ready, Flow
Clone
41802
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC3171U-100UG
Alexa Fluor 405
IC3171V-100UG
Alexa Fluor 488
IC3171G-100UG
Alexa Fluor 532
FAB3171X
Alexa Fluor 594
IC3171T-100UG
Alexa Fluor 647
IC3171R-100UG
Alexa Fluor 700
IC3171N-100UG
Alexa Fluor 750
IC3171S-100UG
Allophycocyanin
IC3171A-025
Allophycocyanin
IC3171A-100
Biotin
FAB3171B
CoraFluor 1
FAB3171CL1
DyLight 350
FAB3171D
DyLight 405
FAB3171E
DyLight 488
FAB3171K
DyLight 550
FAB3171L
DyLight 594
FAB3171M
DyLight 650
FAB3171W
DyLight 680
FAB3171Y
DyLight 755
FAB3171Z
FITC
FAB3171F
HRP
FAB3171H
Janelia Fluor 525
FAB3171JF525
Janelia Fluor 549
FAB3171I
Janelia Fluor 585
FAB3171JF585
Janelia Fluor 635
FAB3171JF635
Janelia Fluor 669
FAB3171JF669
PerCP (Peridinin-chlorophyll Protein Complex)
IC3171C-025
PerCP (Peridinin-chlorophyll Protein Complex)
IC3171C-100
Phycoerythrin
IC3171P-025
Phycoerythrin
IC3171P-100
Unconjugated
MAB3171-100
mFluor Violet 450 SE
FAB3171MFV450
mFluor Violet 500 SE
FAB3171MFV500
mFluor Violet 610 SE
FAB3171MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3171-100
Carrier Free
MAB3171-100
Carrier Free
IC3171U-100UG
Carrier Free
IC3171V-100UG
Carrier Free
IC3171N-100UG
Carrier Free
IC3171R-100UG
Carrier Free
IC3171S-100UG
Carrier Free
MAB3171-500
Carrier Free
MAB3171-SP
Carrier Free
IC3171G-100UG
Carrier Free
IC3171P-025
Carrier Free
IC3171C-025
Carrier Free
IC3171A-025
Carrier Free
IC3171A-100
Carrier Free
IC3171P-100
Carrier Free
IC3171C-100
Carrier Free
IC3171T-100UG
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IL-17/IL-17A Antibody (41802) [Janelia Fluor® 646] Summary

Immunogen
E. coli-derived recombinant human IL-17
Ile20-Ala155
Accession # Q16552
Specificity
Detects human IL-17 in direct ELISAs. In direct ELISAs, 100% cross-reactivity with recombinant human (rh) IL-17A/IL-17F heterodimer is observed. No cross-reactivity with recombinant mouse IL-17, recombinant canine Il-17, rhIL-17B, rhIL-17C, rhIL-17D, rhIL-17E, or rhIL-17F is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IL17A
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Immunohistochemistry
  • Immunoprecipitation
  • Intracellular Staining by Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for IL-17/IL-17A Antibody (41802) [Janelia Fluor® 646]

  • CTLA8
  • CTLA-8
  • CTLA8cytotoxic T-lymphocyte-associated serine esterase 8
  • Cytotoxic T-lymphocyte-associated antigen 8
  • IL17
  • IL-17
  • IL17A
  • IL-17A
  • IL-17Acytotoxic T-lymphocyte-associated protein 8
  • IL-17CTLA-8
  • IL17interleukin-17A
  • interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
  • interleukin 17A

Background

Interleukin 17 (IL-17) is a pro-inflammatory cytokine produced by TCRalpha/beta+ CD4 CD8 thymocytes, as well as by activated CD4+ and CD4+ CD45RO+ memory T cells (1). IL-17 stimulates the expression of TNFalpha, IL-1 beta, IL-6, and IL-8 (2). In addition, IL-17 is involved in the induction of inducible nitric oxide synthase and cyclooxygenase 2 in chondrocytes (3). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis (4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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IL-17/IL-17A
Antibody (41802) [Jan ...
FAB3171J
IL-17/IL-17A Antibody (41802) [Janelia Fluor® 646]
Species: Hu
Applications: WB, IHC, IP, CyTOF-ready, Flow

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for IL-17/IL-17A Antibody (FAB3171J). (Showing 1 - 2 of 2 FAQ).

  1. I want to stain some T cell subsets (Th17 and Th1), do you have antibodies for that? I need for flow cytometer in sheep or goat.
    • Unfortunately, we have neither a CD4 antibody nor an IL-17 antibody that has been validated in sheep or goat, although if you would like to try one you would again be eligible for our Innovators Reward Program. Please contact us at innovators@novusbio.com with any questions regarding this program.
  2. I'm looking to establish an ELISA for IL-17 and want your recommendation on which antibody pairs to buy. Least expensive ones, please. Also, I'd like the detection antibody to be fluorescently labeled.
    • Thank you for your patience while I reviewed our ELISA validated products for IL17. I was not sure what species you were going to be investigating, so I looked up our data for the human protein. If this is incorrect, just let me know and I can look up products for the species you will be working with. As for antibody pairs, we only had one set that have been tested together: Capture: NBP2-22531 Detection: NBP2-22532. The detection product is only available currently with a biotin conjugate. We can however offer custom conjugation for this product to any of our available conjugates. Please see the this link to see the available fluors. The typical fee for custom conjugation is usually about $80 additional. Once you know which fluor you would like, I can provide you with a quote. We do also offer several ELISA kits for this target (they typically employ HRP or Biotin detection systems, so I am not sure if they will work for your needs).

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL17A