HIF-2 alpha/EPAS1 Antibody (2597C) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The Hypoxia-Inducible transcription Factor 2 alpha (HIF-2 alpha ) is stabilized in hypoxic tissue and, similarly to HIF-1 alpha , complexes with Aryl hydrocarbon receptor nuclear translocator (ARNT). Both the HIF-1 and HIF-2 complexes bind hypoxia-response elements (HREs) in the promoters of many genes involved in adapting to an environment of insufficient oxygen or hypoxia. HIF-1 and HIF-2 do not appear completely redundant, although specific functions are only beginning to be elucidated. Hypoxic tissue environments occur in vascular and pulmonary diseases as well as cancer, which illustrates the potentially broad impact of gene regulation by both HIF-1 alpha and HIF-2 alpha .

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array MAB29971

• HIF-2 alpha/EPAS1 Antibodies
• HIF-2 alpha/EPAS1 Antibody Pack
• HIF-2 alpha/EPAS1 Lysate
• HIF-2 alpha/EPAS1 Proteins
• HIF-2 alpha/EPAS1 ELISA