GTF2IRD1 Antibody

GTF2IRD1 is encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing of this gene generates at least 2 transcript variants.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 2 applications: WB, Western Blot.

Showing Publications 1 - 5 of 5.

Publications using NBP1-91973	Applications	Species
Nygaard KR, Maloney SE, Swift RG et al. Extensive characterization of a Williams syndrome murine model shows Gtf2ird1-mediated rescue of select sensorimotor tasks, but no effect on enhanced social behavior Genes, Brain and Behavior 2023-08-01 [PMID: 37370259] (Western Blot)	Western Blot
Kopp N, McCullough K, Maloney SE, Dougherty JD Gtf2i and Gtf2ird1 mutation do not account for the full phenotypic effect of the Williams syndrome critical region in mouse models Hum. Mol. Genet. 2019-08-16 [PMID: 31418010] (Mouse)		Mouse
Hasegawa Y, Ikeda K, Chen Y et al. Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis Cell Metab. 2018-01-09 [PMID: 29320702] (Human)		Human
Kopp, N D, Nygaard, K R Et al. Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA binding and long-term behavioral consequences. Hum Mol Genet 2020-06-03 [PMID: 32313931] (WB, Rat)	WB	Rat

Array NBP1-91973

• GTF2IRD1 Antibodies
• GTF2IRD1 Lysates
• GTF2IRD1 Proteins