Novus Biologicals products are now on bio-techne.com

Growth Hormone Antibody (GH/1371) [Janelia Fluor® 646]

Images

 
There are currently no images for Growth Hormone Antibody (NBP2-54361JF646).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, MA
Clone
GH/1371
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Growth Hormone Antibody (GH/1371) [Janelia Fluor® 646] Summary

Immunogen
A recombinant fragment (around aa58-187) of human Growth Hormone (GH) protein (exact sequence is proprietary) (Uniprot: P01241)
Localization
Cytoplasmic
Marker
Pituitary Marker
Specificity
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
GH1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Protein Array
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Growth Hormone Antibody (GH/1371) [Janelia Fluor® 646]

  • GH1
  • GHB5
  • GHIGHD1B
  • GHN
  • GH-N
  • GHNGrowth hormone
  • GH-Nsomatotropin
  • growth hormone 1Pituitary growth hormone
  • Growth Hormone
  • hGH-N
  • IGHD1A
  • IGHD2
  • Somatotropin

Background

Human growth hormone (hGH) plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. The effects of hGH in the body can be generally described as anabolic. It stimulates amino acid uptake and protein synthesis in muscle and other tissues. Growth Hormone (GH1) is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Genes for growth hormone (GH) are found in a gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. The GHN1 gene is transcribed exclusively in the pituitary, whereas the other 4 genes are expressed only in placental tissues. Several isoforms of GH1 exist. Human growth hormone (hGH) is also used as a reporter protein, because it is secreted from mammalian cells it can be assayed by ELISA on culture supernatant using antibodies to determine the level of expression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AF1067
Species: Hu, Mu, Rt
Applications: ELISA, IHC, Neut, WB
291-G1
Species: Hu
Applications: BA
AF1445
Species: Mu, Rt
Applications: ELISA(Cap), ELISA(Det), ELISA(Sta), IHC, Neut, Simple Western, WB
NBP3-04850
Species: Hu, Mu, Rt
Applications: ICC/IF, WB
MAB1417
Species: Bv, Hu, Mu
Applications: CyTOF-ready, ICC, IHC, ICFlow
H00005087-M01
Species: Hu, Pm, Mu
Applications: ChIP, ELISA, ICC/IF, IHC, IHC-P, IP, S-ELISA, WB
NBP2-37447
Species: Hu
Applications: CyTOF-ready, ELISA, Flow, ICC/IF, IHC, IHC-P, WB
NB100-1533
Species: Hu, Mu, Po, Rt, Sh
Applications: Flow, ICC/IF, IHC, IHC-P, PEP-ELISA, WB
NBP2-34014
Species: Hu
Applications: IHC, IHC-P
DGB300
Species: Hu
Applications: ELISA
NBP2-38770
Species: Hu, Mu
Applications: IHC-P, WB
NBP1-30475
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, IP, WB
AF1360
Species: Mu
Applications: IHC, WB
292-G2
Species: Hu
Applications: BA
MAB8200
Species: Hu, Mu
Applications: IHC
MAB1249
Species: Hu, Mu
Applications: CyTOF-ready, ICC, ICFlow
DY871
Species: Hu
Applications: ELISA
NBP2-92630
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
NBP1-92273
Species: Hu, Mu
Applications: IHC, IHC-P
NBP2-54361JF646
Species: Hu
Applications: IHC, MA

Publications for Growth Hormone Antibody (NBP2-54361JF646) (0)

There are no publications for Growth Hormone Antibody (NBP2-54361JF646).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Growth Hormone Antibody (NBP2-54361JF646) (0)

There are no reviews for Growth Hormone Antibody (NBP2-54361JF646). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Growth Hormone Antibody (NBP2-54361JF646) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Growth Hormone Products

Research Areas for Growth Hormone Antibody (NBP2-54361JF646)

Find related products by research area.

Blogs on Growth Hormone.

Growth hormone (GH, somatotropin, hGH, pituitary growth hormone)
GH is a member of the large family of growth factors that includes prolactin, placental lactogens, proliferins, and somatolactin. Additionally, GH is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic ...  Read full blog post.

Somatostatin Receptor 2: Treating Patients Who Cannot Stop Growing
Acromegaly is a rare life-shortening disease caused by elevated levels of growth hormone (GH) secreted by a tumor on the pituitary gland. Treatments include somatostatin analogs, which activate somatostatin receptor 2 (SSTR2), reducing GH secretion an...  Read full blog post.

mFluor Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Growth Hormone Antibody (GH/1371) [Janelia Fluor® 646] and receive a gift card or discount.

Bioinformatics

Gene Symbol GH1