Glut2 Antibody Summary
Immunogen |
Synthetic peptide C-RKEREEASSEQKVS from an internal region of human Glut2 (NP_000331.1). |
Epitope |
C-RKEREEASSEQKVS from an internal region |
Predicted Species |
Porcine (93%), Rabbit (93%), Primate (93%), Equine (93%), Monkey (93%), Bat (93%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Goat |
Gene |
SLC2A2 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 10 ug/ml
- Immunofluorescence 10 ug/ml
- Immunohistochemistry 2-6 ug/ml
- Immunohistochemistry-Paraffin 2.5 ug/ml
- Peptide ELISA 1:8000
|
Application Notes |
. |
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (93%), Rat (86%), Sheep (86%), Canine (86%), Bovine (86%).
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
TBS (pH 7.3) and 0.5% BSA |
Preservative |
0.02% Sodium Azide |
Concentration |
0.5 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for Glut2 Antibody
Background
Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. Seven types of glucose transport carrier proteins, designated as Glut 1 to 7, facilitate glucose transport across the cell membrane. Molecular cloning of glucose transporters have identified a family of closely related genes that encode at least 7 proteins exhibiting high degree of amino acid homology (45% to 65%), all in the molecular weight range of 40 to 60 kDa. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers. The majority of differences in sequence homology in Glut proteins occur at 4 hydrophilic domains that may play a role in distinct tissue specific pattern of expression and targeting. All Glut proteins are glycosylated at or near the C terminus and are present on either cell surface or in intracellular sites. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. In some tissues Glut proteins are asymmetrically distributed between apical and basolateral membranes as in blood brain barrier and blood testis barriers.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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FAQs for Glut2 Antibody (NBP1-52560). (Showing 1 - 1 of 1 FAQ).
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Could you help this customer find a monoclonal antibody specific to rat's Glut2 protein to be used in IHC. I looked on our website and found one specific to Human's Glut2. Does this one cross react with Rat as well?
- I have found the following antibody that would be suitable for you: NBP1-52560 I have included the peptide sequence below for the customer so that they can verify the homology with Rat. It is predicted and guaranteed to work in rat samples based on the sequence homology. If this antibody does not perform as expected you may receive a refund or replacement.