Ghrelin/Obestatin Antibody (45) [Janelia Fluor® 525] Summary
Immunogen |
Synthetic human Ser3-octanoyl ghrelin-28 |
Epitope |
Not determined. Probably includes residues 11 or 12 to account for the lower cross-reactivity with rat ghrelin |
Specificity |
Binds human octanoylated ghrelin and human des-acyl ghrelin. |
Isotype |
IgG1 Lambda |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
GHRL |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A or G purified |
Notes
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
Alternate Names for Ghrelin/Obestatin Antibody (45) [Janelia Fluor® 525]
Background
Ghrelin is a 28 residue pepetide expressed by stomach cells that is responsible for the hunger sensation. Expression is increased during times of fasting, and decreased after food consumption. Ghrelin is initially derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and decreased food intake. Ghrelin antibodies are useful tools for lipid and metabolism research as well as neuroscience studies.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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