Name: Galectin-9 Antibody [Unconjugated]
Brand: Novus Biologicals
SKU: AF2045
Rating: 5 (1 reviews)

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	WB, IHC, ICC/IF
Clonality	Polyclonal
Host	Goat
Conjugate	Unconjugated
Concentration	LYOPH

Catalog# & Conjugate	Size	Price
Biotin BAF2045

Catalog# & Formulation	Size	Price
Carrier Free AF2045-SP

Conjugate	Catalog #	Availability	Size	Price
Biotin	BAF2045

Galectin-9 Antibody [Unconjugated]

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Publications for Galectin-9 Antibody (AF2045)(21)

Review for Galectin-9 Antibody (AF2045) (1) 51

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Immunogen	E. coli-derived recombinant human Galectin-9
Specificity	Detects human Galectin-9 in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human (rh) Galectin-3 and rhGalectin-4 is observed and less than 2% cross-reactivity with rhGalectin-1, rhGalectin-2, rhGalectin-7, and rhGalectin-8 is observed.
Source	N/A
Isotype	IgG
Clonality	Polyclonal
Host	Goat
Gene	LGALS9
Purity Statement	Antigen Affinity-purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.2 mg/mL in sterile PBS.

Publications using AF2045	Applications	Species
Santalla M�ndez R, Rodgers Furones A, Classens R et al. Galectin-9 interacts with Vamp-3 to regulate cytokine secretion in dendritic cells Cell Mol Life Sci 2023-09-27 [PMID: 37755527]
Santalla M�ndez R, Rodgers Furones A, Classens R et al. Galectin-9 interacts with Vamp-3 to regulate cytokine secretion in dendritic cells Cell Mol Life Sci 9/27/2023 [PMID: 37755527]
MA Nielsen, D Køster, AY Mehta, K Stengaard-, P Busson, P Junker, K Hørslev-Pe, ML Hetland, M Østergaard, M Hvid, H Leffler, TW Kragstrup, RD Cummings, B Deleuran Increased Galectin-9 Levels Correlate with Disease Activity in Patients with DMARD-Naï¿½ve Rheumatoid Arthritis and Modulate the Secretion of MCP-1 and IL-6 from Synovial Fibroblasts Cells, 2023-01-15;12(2):. 2023-01-15 [PMID: 36672263] (Binding Assay, Human)	Binding Assay	Human
Stephanie J. Si, Gerald B. Wertheim, David M. Barrett High Expression of TIM 3 and Galectin 9 on Immunohistochemistry Staining of Tumor Specimen at Diagnosis in Pediatric Patients with Ewing Sarcoma J Cancer Immunol (Wilmington) 6/30/2022 [PMID: 35938052]
Marco Frensch, Christina Jäger, Peter F. Müller, Annamaria Tadić, Isabel Wilhelm, Sarah Wehrum et al. Bacterial lectin BambL acts as a B cell superantigen Cellular and Molecular Life Sciences 12/1/2021 [PMID: 34731252]
Qin Chen, Xiaoming Zhou, Ruonan Hou, Zhiliang Zhou, Zhiyi Wang, Ying Chen et al. Aminophylline modulates the permeability of endothelial cells via the Slit2‑Robo4 pathway in lipopolysaccharide‑induced inflammation Experimental and Therapeutic Medicine 7/21/2021 [PMID: 34373728]
JN Sudhakar, HH Lu, HY Chiang, CS Suen, MJ Hwang, SY Wu, CN Shen, YM Chang, FA Li, FT Liu, JW Shui Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas Nat Commun, 2020-08-27;11(1):4286. 2020-08-27 [PMID: 32855403] (Western Blot, Mouse)	Western Blot	Mouse
K Sideras, RA de Man, SM Harrington, WG Polak, G Zhou, HM Schutz, A Pedroza-Go, K Biermann, S Mancham, BE Hansen, R Bart Takke, AJ van Vuuren, Q Pan, JNM Ijzermans, S Sleijfer, D Sprengers, H Dong, J Kwekkeboom, MJ Bruno Circulating levels of PD-L1 and Galectin-9 are associated with patient survival in surgically treated Hepatocellular Carcinoma independent of their intra-tumoral expression levels Sci Rep, 2019-07-23;9(1):10677. 2019-07-23 [PMID: 31337865] (IHC-P, Human)	IHC-P	Human
X Zhang, D He, S Gao, Y Wei, L Wang Aspergillusï¿½fumigatus enhances human NK cell activity by regulating M1 macrophage polarization Mol Med Rep, 2019-06-06;20(2):1241-1249. 2019-06-06 [PMID: 31173233] (Cell Culture, Western Blot, Human)	Cell Culture, Western Blot	Human
JT Schroeder, AP Bieneman Activation of Human Basophils by A549 Lung Epithelial Cells Reveals a Novel IgE-Dependent Response Independent of Allergen J. Immunol., 2017-06-26;0(0):. 2017-06-26 [PMID: 28652400] (Neutralization, Human)	Neutralization	Human
Sun J, Yang M, Ban Y, Gao W, Song B, Wang Y, Zhang Y, Shao Q, Kong B, Qu X Tim-3 Is Upregulated in NK Cells during Early Pregnancy and Inhibits NK Cytotoxicity toward Trophoblast in Galectin-9 Dependent Pathway. PLoS ONE, 2016-01-20;11(1):e0147186. 2016-01-20 [PMID: 26789128] (IHC-P, Human)	IHC-P	Human
Punt S, Thijssen V, Vrolijk J, de Kroon C, Gorter A, Jordanova E Galectin-1, -3 and -9 Expression and Clinical Significance in Squamous Cervical Cancer. PLoS ONE, 2015-06-12;10(6):e0129119. 2015-06-12 [PMID: 26066796] (IHC-P, Human)	IHC-P	Human
Leskela S, Serrano A, de la Fuente H, Rodriguez-Munoz A, Ramos-Levi A, Sampedro-Nunez M, Sanchez-Madrid F, Gonzalez-Amaro R, Marazuela M Graves' disease is associated with a defective expression of the immune regulatory molecule galectin-9 in antigen-presenting dendritic cells. PLoS ONE, 2015-04-16;10(4):e0123938. 2015-04-16 [PMID: 25880730] (Flow Cytometry, IHC-Fr, Human)	Flow Cytometry, IHC-Fr	Human
Schulkens I, Heusschen R, van den Boogaart V, van Suylen R, Dingemans A, Griffioen A, Thijssen V Galectin expression profiling identifies galectin-1 and Galectin-9Delta5 as prognostic factors in stage I/II non-small cell lung cancer. PLoS ONE, 2014-09-26;9(9):e107988. 2014-09-26 [PMID: 25259711] (IHC-P, Western Blot, Human)	IHC-P, Western Blot	Human
McSharry B, Forbes S, Cao J, Avdic S, Machala E, Gottlieb D, Abendroth A, Slobedman B Human cytomegalovirus upregulates expression of the lectin galectin 9 via induction of beta interferon. J Virol, 2014-07-09;88(18):10990-4. 2014-07-09 [PMID: 25008927] (Western Blot, Human)	Western Blot	Human
Clayton K, Haaland M, Douglas-Vail M, Mujib S, Chew G, Ndhlovu L, Ostrowski M T cell Ig and mucin domain-containing protein 3 is recruited to the immune synapse, disrupts stable synapse formation, and associates with receptor phosphatases. J Immunol, 2013-12-13;192(2):782-91. 12/13/2013 [PMID: 24337741]
Leitner , Judith, Rieger , Armin, Pickl , Winfried, Zlabinger , Gerhard, Grabmeier-Pfistershammer , Katharin, Steinberger , Peter TIM-3 does not act as a receptor for galectin-9. PLoS Pathog, 2013-03-21;9(3):e1003253. 2013-03-21 [PMID: 23555261] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Nebbia G, Peppa D, Schurich A, Khanna P, Singh H, Cheng Y, Rosenberg W, Dusheiko G, Gilson R, Chinaleong J, Kennedy P, Maini M Upregulation of the tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection. PLoS ONE, 2012-10-24;7(10):e47648. 2012-10-24 [PMID: 23112829] (IHC-Fr, Human)	IHC-Fr	Human
Baitsch L, Legat A, Barba L, Fuertes Marraco SA, Rivals JP, Baumgaertner P, Christiansen-Jucht C, Bouzourene H, Rimoldi D, Pircher H, Rufer N, Matter M, Michielin O, Speiser DE Extended co-expression of inhibitory receptors by human CD8 T-cells depending on differentiation, antigen-specificity and anatomical localization. PLoS ONE, 2012-02-08;7(2):e30852. 2012-02-08 [PMID: 22347406] (IHC-P, Human)	IHC-P	Human
Mengshol JA, Golden-Mason L, Arikawa T A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection. PLoS ONE, 2010-03-04;5(3):e9504. 2010-03-04 [PMID: 20209097] (IHC-P, Western Blot, Human)	IHC-P, Western Blot	Human
Thijssen VL, Hulsmans S, Griffioen AW The galectin profile of the endothelium: altered expression and localization in activated and tumor endothelial cells. Am. J. Pathol., 2008-01-17;172(2):545-53. 2008-01-17 [PMID: 18202194] (Flow Cytometry, ICC, IHC-P, Western Blot, Human)	Flow Cytometry, ICC, IHC-P, Western Blot	Human
Show All 21 Publications. Collapse Publications.

	Verified Customer 04/04/2020
Application:	IHC-P
Species:	Human