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DGAT1 Antibody [mFluor Violet 450 SE]

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Product Details

Summary
Reactivity Hu, Mu, Rt, PmSpecies Glossary
Applications WB, ICC/IF, WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
mFluor Violet 450 SE

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DGAT1 Antibody [mFluor Violet 450 SE] Summary

Immunogen
A synthetic peptide made to an internal region (within residues 200-300) of human DGAT1. [Swiss-Prot# O75907]
Localization
Endoplasmic reticulum; endoplasmic reticulum membrane multi-pass membrane protien.
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DGAT1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunoblotting
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Use in Rat reported in scientific literature (PMID:32326330).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DGAT1 Antibody [mFluor Violet 450 SE]

  • ACAT-related gene product 1
  • AGRP1
  • ARAT
  • ARGP1
  • ARGP1acyl coenzyme A:cholesterol acyltransferase related gene 1
  • DGAT
  • DGAT1
  • DGATACAT related gene product 1
  • diacylglycerol O-acyltransferase 1
  • diacylglycerol O-acyltransferase homolog 1 (mouse)
  • diacylglycerol O-acyltransferase homolog 1
  • DIAR7
  • Diglyceride acyltransferase
  • EC 2.3.1
  • EC 2.3.1.20

Background

Diglyceride acyltransferase (DGAT) is a membrane-bound Sterol o-acyltransferase subfamily member. DGAT1 is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. Specifically, it catalyzes the terminal step in triacylglycerol synthesis, using diacylglycerol (DAG) and fatty acyl CoA as substrates.

DGAT plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism such as intestinal fat absorption, lipoprotein assembly, adipose tissue formation, and lactation. DGAT1 is involved in fat absorption in the intestine and in basal level triglyceride synthesis in adipose tissue, where it is more highly expressed.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for DGAT1 Antibody (NB110-41487MFV450) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for DGAT1 Antibody (NB110-41487MFV450)

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Blogs on DGAT1.

Can you DGAT? DGAT1 & DGAT2 Antibodies for Metabolic Pathway Research
Triacylglycerols (triglycerides) (TGs) are the major storage molecules of metabolic energy and FAs in most living organisms. Excessive accumulation of TGs, however, is associated with human diseases, such as obesity, diabetes mellitus, and steatohepat...  Read full blog post.

mFluor Violet Conjugated Antibodies

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Bioinformatics

Gene Symbol DGAT1