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CXCR1/IL-8RA Antibody (42705) [Phycoerythrin]

Images

 
Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR1/IL-8 RA PE-conjugated Monoclonal Antibody (Catalog # FAB330P, filled histogram) or isotype control antibody (Catalog # IC003P, open ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
42705
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

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CXCR1/IL-8RA Antibody (42705) [Phycoerythrin] Summary

Additional Information
Clone 42705 was used by HLDA to establish CD designation
Immunogen
NS0 mouse myeloma cell line transfected with human CXCR1/IL-8 RA
Met1-Leu350
Accession # AAA59159
Specificity
Detects human CXCR1/IL-8 RA transfectants but not the parental cell line. It does not cross-react with human CXCR2.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CXCR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Reviewed Applications
Read 2 Reviews rated 5
using
FAB330P in the following application:

Publications
Read Publications using
FAB330P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CXCR1/IL-8RA Antibody (42705) [Phycoerythrin]

  • CD128
  • CD181 antigen
  • CD181
  • CDw128aC-C
  • chemokine (C-X-C motif) receptor 1
  • CKR-1
  • CMKAR1
  • C-X-C chemokine receptor type 1
  • CXCR1
  • CXC-R1
  • CXCR-1
  • High affinity interleukin-8 receptor A
  • IL-8 RA
  • IL-8 receptor type 1
  • IL-8R A
  • IL8R1
  • IL8RA
  • IL8RAC-C-CKR-1
  • IL8RBA
  • interleukin 8 receptor, alpha
  • interleukin-8 receptor type 1
  • interleukin-8 receptor type A

Background

The human C-X-C chemokine IL-8 is a potent neutrophil chemotactic and activating factor. Two distinct G protein-linked cell surface receptors, known as IL-8 RA (type I or CXCR1) and IL-8 RB (type II or CXCR2), can interact with the IL-8 molecule. These two receptors share 77% amino acid homology. CXCR1 expression has been documented on neutrophils, monocytes, and a small population of T cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CXCR1/IL-8RA Antibody (FAB330P)(16)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(16)
All Applications
Filter By Species
Human
(16)
All Species
Showing Publications 1 - 10 of 16. Show All 16 Publications.
Publications using FAB330P Applications Species
S McKenna, SP Giblin, RA Bunn, Y Xu, SJ Matthews, JE Pease A highly efficient method for the production and purification of recombinant human CXCL8 PLoS ONE, 2021-10-15;16(10):e0258270. 2021-10-15 [PMID: 34653205] (Flow Cytometry, Human) Flow Cytometry Human
F Askarian, S Uchiyama, H Masson, HV Sørensen, O Golten, AC Bunæs, S Mekasha, ÅK Røhr, E Kommedal, JA Ludviksen, MØ Arntzen, B Schmidt, RH Zurich, NM van Sorge, VGH Eijsink, U Krengel, TE Mollnes, NE Lewis, V Nizet, G Vaaje-Kols The lytic polysaccharide monooxygenase CbpD promotes Pseudomonas aeruginosa virulence in systemic infection Nature Communications, 2021-02-23;12(1):1230. 2021-02-23 [PMID: 33623002] (Flow Cytometry, Human) Flow Cytometry Human
RC Fisher, K Bellamkond, L Alex Molin, S Xiang, D Liska, SK Sarvestani, S Chakrabart, A Berg, ML Jorgensen, D Hatala, S Chen, A Aiello, HD Appelman, EW Scott, EH Huang Disrupting Inflammation-Associated CXCL8-CXCR1 Signaling Inhibits Tumorigenicity Initiated by Sporadic- and Colitis-Colon Cancer Stem Cells Neoplasia, 2019-02-07;21(3):269-281. 2019-02-07 [PMID: 30738331] (Flow Cytometry, Human) Flow Cytometry Human
Cerdeira A, Rajakumar A, Royle C, Lo A, Husain Z, Thadhani R, Sukhatme V, Karumanchi S, Kopcow H Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors. J Immunol, 2013-03-13;190(8):3939-48. 2013-03-13 [PMID: 23487420] (Flow Cytometry, Human) Flow Cytometry Human
Sela H, Goldman-Wohl D, Haimov-Kochman R, Greenfield C, Natanson-Yaron S, Hamani Y, Revel A, Lavy Y, Singer O, Yachimovich-Cohen N, Turetsky T, Mandelboim O, Reubinoff B, Yagel S Human trophectoderm apposition is regulated by interferon gamma-induced protein 10 (IP-10) during early implantation. Placenta, 2013-01-08;34(3):222-30. 2013-01-08 [PMID: 23306067] (Flow Cytometry, Human) Flow Cytometry Human
Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis. EMBO J., 2012-07-31;31(17):3607-19. 2012-07-31 [PMID: 22850671] (Flow Cytometry, Human) Flow Cytometry Human
Vujanovic , Lazar, Ballard , Wenners, Thorne , Stephen, Vujanovic , Nikola L, Butterfield , Lisa H Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10. Oncoimmunology, 2012-07-01;1(4):448-457. 2012-07-01 [PMID: 22754763] (Flow Cytometry, Human) Flow Cytometry Human
McDermott DH, De Ravin SS, Jun HS Severe congenital neutropenia resulting from G6PC3 deficiency with increased neutrophil CXCR4 expression and myelokathexis. Blood, 2010-07-08;116(15):2793-802. 2010-07-08 [PMID: 20616219] (Flow Cytometry, Human) Flow Cytometry Human
Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J. Immunol., 2010-02-17;184(6):2886-98. 2010-02-17 [PMID: 20164417] (Flow Cytometry, Human) Flow Cytometry Human
Carbone T, Nasorri F, Pennino D CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses. J. Immunol., 2009-12-11;184(2):1102-10. 2009-12-11 [PMID: 20008290] (Flow Cytometry, Human) Flow Cytometry Human
Show All 16 Publications.

Reviews for CXCR1/IL-8RA Antibody (FAB330P) (2) 52

Average Rating: 5
(Based on 2 reviews)
We have 2 reviews tested in 1 species: Human.

Reviews using FAB330P:
Filter by Applications
Flow
(2)
All Applications
Filter by Species
Human
(2)
All Species
Images Ratings Applications Species Date Details
  5
reviewed by:
Verified Customer
Flow Human 01/23/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 22754763
SpeciesHuman
  5
reviewed by:
Verified Customer
Flow Human 01/23/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 22754763
SpeciesHuman

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FAQs for CXCR1/IL-8RA Antibody (FAB330P) (0)

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Recent Reviews

5
5
2
4
0
3
0
2
0
1
0

 
Verified Customer
01/23/2015
Application: Flow
Species: Human

 
Verified Customer
01/23/2015
Application: Flow
Species: Human

Bioinformatics

Gene Symbol CXCR1
Uniprot