CX3CR1 Antibody [Alexa Fluor® 488]

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CX3CR1 (CX₃C chemokine receptor 1; also fractalkine receptor, GPCR13 and V28) is a 40 kDa member of the δ-group of rhodopsin GPCRs. It is expressed on astrocytes, microglia, macrophages, Th1 and Tc1 T cells, NK cells, mouse Gr1^lo monocytes plus smooth muscle and mast cells. CX₃CR1 mediates adhesion to fractalkine, promotes avid binding of integrins to their ligands, and extends the life of monocytes. Mouse CX3CR1 is a 7-transmembrane protein that is 354 amino acids (aa) in length. It contains a 32 aa N-terminal extracellular region that shows no glycosylation, and a 56 aa C-terminal cytoplasmic domain. Over aa 1‑32, 91‑104, 169‑196 and 258‑274 collectively, mouse CX₃CR1 shares 96% and 77% aa identity with rat and human CX₃CR1, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: Flow Cytometry.

Showing Publications 1 - 4 of 4.

Publications using FAB5825G	Applications	Species
A Nakamura, S Kurihara, D Takahashi, W Ohashi, Y Nakamura, S Kimura, M Onuki, A Kume, Y Sasazawa, Y Furusawa, Y Obata, S Fukuda, S Saiki, M Matsumoto, K Hase Symbiotic polyamine metabolism regulates epithelial proliferation and macrophage differentiation in the colon Nature Communications, 2021-04-08;12(1):2105. 2021-04-08 [PMID: 33833232] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
M Chen, J Zhao, IH Ali, S Marry, J Augustine, M Bhuckory, A Lynch, A Kissenpfen, H Xu SOCS3 deficiency in myeloid cells promotes retinal degeneration and angiogenesis through arginase-1 up-regulation in experimental autoimmune uveoretinitis Am. J. Pathol., 2018-02-13;0(0):. 2018-02-13 [PMID: 29452101] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
A Voisin, M Whitfield, C Damon-Soub, C Goubely, J Henry-Berg, F Saez, A Kocer, JR Drevet, R Guiton Comprehensive overview of murine epididymal mononuclear phagocytes and lymphocytes: Unexpected populations arise J. Reprod. Immunol., 2018-01-31;126(0):11-17. 2018-01-31 [PMID: 29421624] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
Nie P, Li D, Hu L, Jin S, Yu Y, Cai Z, Shao Q, Shen J, Yi J, Xiao H, Shen L, He B Atorvastatin improves plaque stability in ApoE-knockout mice by regulating chemokines and chemokine receptors. PLoS ONE, 2014-05-09;9(5):e97009. 2014-05-09 [PMID: 24816562] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse

Array FAB5825G

• CX3CR1 Antibodies
• CX3CR1 ELISA Kits
• CX3CR1 Proteins