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CD4 Antibody (11830) [Allophycocyanin]

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Human peripheral blood lymphocytes were stained with (A) Mouse Anti-Human CD4 APC-conjugated Monoclonal Antibody (Catalog # FAB3791A) or (B) Mouse IgG2AAllophycocyanin Isotype Control (Catalog # IC003A) and Mouse Anti-Human CD3e CFS-conjugated Monoclonal Antibody (Catalog # FAB100F). View our protocol for Staining Membrane-associated Proteins.
Human peripheral blood lymphocytes were stained with (A) Mouse Anti-Human CD4 APC-conjugated Monoclonal Antibody (Catalog # FAB3791A) or (B) Mouse IgG2AAllophycocyanin Isotype Control (Catalog # IC003A) and Mouse ...read more
CD4 knock-down in genetically modified stem cell-derived macrophages.A) Schematic diagrams of self-inactivating lentiviral constructs used to express a shRNA (non-specific short-hairpin control (shCNTRL) or a short ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
11830
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB37911U
Alexa Fluor 405
FAB3791V-025
Alexa Fluor 405
FAB37911V
Alexa Fluor 488
FAB3791G-100
Alexa Fluor 532
FAB37911X
Alexa Fluor 594
FAB37911T
Alexa Fluor 594
FAB3791T-025
Alexa Fluor 594
FAB3791T-100
Alexa Fluor 647
FAB3791R-100UG
Alexa Fluor 647
FAB37911R
Alexa Fluor 700
FAB3791N-025
Alexa Fluor 700
FAB3791N-100
Alexa Fluor 700
FAB37911N
Alexa Fluor 750
FAB37911S
Alexa Fluor 750
FAB3791S-025
Alexa Fluor 750
FAB3791S-100
Allophycocyanin
FAB37911A
Allophycocyanin
FAB3791A-025
Allophycocyanin/Cy7
FAB37911APCCY7
Biotin
FAB37911B
DyLight 350
FAB37911D
DyLight 405
FAB37911E
DyLight 488
FAB37911K
DyLight 550
FAB37911L
DyLight 594
FAB37911M
DyLight 650
FAB37911W
DyLight 680
FAB37911Y
DyLight 755
FAB37911Z
Fluorescein
FAB3791F-025
Fluorescein
FAB3791F-100
HRP
FAB37911H
Janelia Fluor 549
FAB37911I
Janelia Fluor 646
FAB37911J
PE/Atto594
FAB37911PEATT594
PE/Cy5.5
FAB37911PECY55
PE/Cy7
FAB37911PECY7
PerCP (Peridinin-chlorophyll Protein Complex)
FAB3791C-100
PerCP (Peridinin-chlorophyll Protein Complex)
FAB3791C-025
Phycoerythrin
FAB3791P-025
Phycoerythrin
FAB3791P-100
Unconjugated
MAB37911-100
mFluor Violet 450 SE
FAB37911MFV450
mFluor Violet 500 SE
FAB37911MFV500
mFluor Violet 610 SE
FAB37911MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB37911-100
Carrier Free
FAB3791N-025
Carrier Free
MAB37911-100
Carrier Free
FAB3791V-025
Carrier Free
FAB3791T-025
Carrier Free
FAB3791T-100
Carrier Free
FAB3791S-025
Carrier Free
FAB3791S-100
Carrier Free
FAB3791P-025
Carrier Free
FAB3791F-025
Carrier Free
FAB3791R-100UG
Carrier Free
FAB3791C-025
Carrier Free
FAB3791A-025
Carrier Free
FAB3791N-100
Carrier Free
FAB3791G-100
Carrier Free
FAB3791P-100
Carrier Free
FAB3791F-100
Carrier Free
FAB3791C-100
Carrier Free
MAB37911-SP
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CD4 Antibody (11830) [Allophycocyanin] Summary

Immunogen
Recombinant Human CD4.
Extracellular Domain
Accession # P01730
Specificity
Detects human CD4 in direct ELISAs.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CD4
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB3791A in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD4 Antibody (11830) [Allophycocyanin]

  • CD_antigen: CD4
  • CD4 antigen (p55)
  • CD4 antigen
  • CD4 molecule
  • CD4 receptor
  • CD4
  • CD4mut
  • T-cell surface antigen T4/Leu-3
  • T-cell surface glycoprotein CD4

Background

CD4 is a type I membrane glycoprotein belonging to the immunoglobulin superfamily. It is expressed predominantly on thymocytes and a subset of mature T lymphocytes. CD4 functions in collaboration with the T cell receptor in the recognition of peptide antigens that are presented by class II major histocompatibility complexes. CD4 also has been shown to be a coreceptor of HIV entry and specifically binds gp120, the external envelope glycoprotein of HIV.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD4 Antibody (FAB3791A)(8)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(8)
All Applications
Filter By Species
Human
(8)
All Species
Showing Publications 1 - 8 of 8.
Publications using FAB3791A Applications Species
M Beki?, M Vasiljevi?, D Stojanovi?, V Kokol, D Mihajlovi?, D Vu?evi?, P Uskokovi?, M ?oli?, S Tomi? Phosphonate-Modified Cellulose Nanocrystals Potentiate the Th1 Polarising Capacity of Monocyte-Derived Dendritic Cells via GABA-B Receptor International Journal of Nanomedicine, 2022-07-23;17(0):3191-3216. 2022-07-23 [PMID: 35909813] (Flow Cytometry, Human) Flow Cytometry Human
M Mazuz, A Tiroler, L Moyal, E Hodak, S Nadarajan, AC Vinayaka, B Gorovitz-H, I Lubin, A Drori, G Drori, OV Cauwenberg, A Faigenboim, D Namdar, I Amitay-Lai, H Koltai Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Oncotarget, 2020-03-31;11(13):1141-1156. 2020-03-31 [PMID: 32284791] (Flow Cytometry, Human) Flow Cytometry Human
M Gaggianesi, A Turdo, A Chinnici, E Lipari, T Apuzzo, A Benfante, I Sperduti, S Di Franco, S Meraviglia, E Lo Presti, F Dieli, V Caputo, G Militello, S Vieni, G Stassi, M Todaro IL-4 primes the dynamics of breast cancer progression via DUSP4 inhibition Cancer Res., 2017-04-11;0(0):. 2017-04-11 [PMID: 28400477] (Flow Cytometry, Human) Flow Cytometry Human
Wang L, Qiu J, Yu L, Hu X, Zhao P, Jiang Y Increased numbers of CD5+CD19+CD1dhighIL-10+ Bregs, CD4+Foxp3+ Tregs, CD4+CXCR5+Foxp3+ follicular regulatory T (TFR) cells in CHB or CHC patients. J Transl Med, 2014-09-09;12(0):251. 2014-09-09 [PMID: 25199644] (Flow Cytometry, Human) Flow Cytometry Human
van Wilgenburg , Bonnie, Moore , Michael, James , William, Cowley , Sally A The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4. PLoS ONE, 2014-01-22;9(1):e86071. 2014-01-22 [PMID: 24465876] (Flow Cytometry, Human) Flow Cytometry Human
Fujii H, Arakawa A, Utsumi D, Sumiyoshi S, Yamamoto Y, Kitoh A, Ono M, Matsumura Y, Kato M, Konishi K, Shiga T, Sano S, Sakaguchi S, Miyagawa-Hayashino A, Takahashi K, Uezato H, Miyachi Y, Tanioka M CD8(+) tumor-infiltrating lymphocytes at primary sites as a possible prognostic factor of cutaneous angiosarcoma. Int J Cancer, 2013-11-18;134(10):2393-402. 2013-11-18 [PMID: 24243586] (Flow Cytometry, Human) Flow Cytometry Human
Suzuki H, Onishi H, Wada J, Yamasaki A, Tanaka H, Nakano K, Morisaki T, Katano M VEGFR2 is selectively expressed by FOXP3high CD4+ Treg. Eur. J. Immunol., 2010-01-01;40(1):197-203. 2010-01-01 [PMID: 19902430] (Flow Cytometry, Human) Flow Cytometry Human
Hirahara K, Liu L, Clark RA, Yamanaka K, Fuhlbrigge RC, Kupper TS The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors. J. Immunol., 2006-10-01;177(7):4488-94. 2006-10-01 [PMID: 16982885] (Flow Cytometry, Human) Flow Cytometry Human

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for CD4 Antibody (FAB3791A). (Showing 1 - 1 of 1 FAQs).

  1. I want to stain some T cell subsets (Th17 and Th1), do you have antibodies for that? I need for flow cytometer in sheep or goat.
    • Unfortunately, we have neither a CD4 antibody nor an IL-17 antibody that has been validated in sheep or goat, although if you would like to try one you would again be eligible for our Innovators Reward Program. Please contact us at innovators@novusbio.com with any questions regarding this program.

Secondary Antibodies

 

Isotype Controls

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By Jamshed Arslan, Pharm D, PhDWhat do nuts, dairy and red meat have in common? In addition to the fact that they are all edible, one of the answers is L-arginine. This amino acid improves T cell’s respons...  Read full blog post.
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By Jamshed Arslan, Pharm. D., PhD. Colon cancer is responsible for over 600,000 deaths per year worldwide. Colon cancer can be classified into two categories: mismatch repair (MMR)-deficient and MMR-proficient cancers...  Read full blog post.
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By Yoskaly Lazo-Fernandez, PhD The mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that, as a member of two distinct intracellular protein complexes, mTORC1 and mTORC2, regulates protein ...  Read full blog post.
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Bioinformatics

Gene Symbol CD4
Uniprot