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CCR6 Antibody (140706) [Phycoerythrin]

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Mouse splenocytes were stained with Rat Anti-Mouse B220/CD45R APC-conjugated Monoclonal Antibody (Catalog # FAB1217A) and either (A) Rat Anti-Human/Mouse CCR6 PE-conjugated Monoclonal Antibody (Catalog # FAB590P) or (B) ...read more
Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD19 APC-conjugated Monoclonal Antibody (Catalog # FAB4867A) and either (A) Rat Anti-Human/Mouse CCR6 PE-conjugated Monoclonal Antibody (Catalog # ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications Flow
Clone
140706
Clonality
Monoclonal
Host
Rat
Conjugate
Phycoerythrin

Order Details

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CCR6 Antibody (140706) [Phycoerythrin] Summary

Immunogen
RBL-1 rat basophilic leukemia cell line transfected with mouse CCR6
Met1-Met367
Accession # O54689
Specificity
Detects mouse CCR6-transfected rat RBL cells but not the parent cell line or cells transfected with mouse CCR5. Detects human CCR6 in flow cytometry.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
CCR6
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB590P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCR6 Antibody (140706) [Phycoerythrin]

  • BN-1
  • CC-CKR-6
  • CCR6
  • CCR-6
  • CD196 antigen
  • CD196
  • chemokine (C-C motif) receptor 6
  • CKRL3
  • CKR-L3
  • CKR-L3G-protein coupled receptor 29
  • CKRL3LARC receptor
  • CMKBR6
  • CMKBR6STRL22
  • DRY6
  • GPR29
  • GPR29C-C CKR-6
  • GPRCY4
  • GPR-CY4
  • GPRCY4DRY-6
  • lymphocyte, 22
  • STRL22

Background

CCR6 is a seven transmembrane-spanning G protein-coupled receptor that binds the chemokine MIP-3 alpha and mediates the chemoattraction of B and T lymphocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CCR6 Antibody (FAB590P)(19)

We have publications tested in 3 confirmed species: Human, Mouse, Hamster.

We have publications tested in 2 applications: Flow Cytometry, ICC.


Filter By Application
Flow Cytometry
(15)
ICC
(1)
All Applications
Filter By Species
Human
(1)
Mouse
(14)
Hamster
(1)
All Species
Showing Publications 1 - 10 of 19. Show All 19 Publications.
Publications using FAB590P Applications Species
Spencer T. Chen, Thiago Y. Oliveira, Anna Gazumyan, Melissa Cipolla, Michel C. Nussenzweig B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection Immunity 3/14/2023 [PMID: 36882061]
K Oishi, S Horiuchi, J Frere, RE Schwartz, BR tenOever A diminished immune response underlies age-related SARS-CoV-2 pathologies Cell Reports, 2022-06-09;39(13):111002. 2022-06-09 [PMID: 35714615] (Flow Cytometry, Hamster) Flow Cytometry Hamster
Carina A. Bäuerlein, Musga Qureischi, Zeinab Mokhtari, Paula Tabares, Christian Brede, Ana-Laura Jordán Garrote et al. A T-Cell Surface Marker Panel Predicts Murine Acute Graft-Versus-Host Disease Frontiers in Immunology 1/29/2021 [PMID: 33584657]
M Picard, S Yonekura, K Slowicka, I Petta, C Rauber, B Routy, C Richard, V Iebba, M Tidjani Al, S Becharef, P Ly, E Pizzato, CHK Lehmann, L Amon, C Klein, P Opolon, I Gomperts B, JY Scoazec, A Hollebecqu, D Malka, F Ghiringhel, D Dudziak, G Berx, L Vereecke, G van Loo, G Kroemer, L Zitvogel, MP Roberti Ileal immune tonus is a prognosis marker of proximal colon cancer in mice and patients Cell Death and Differentiation, 2020-12-01;0(0):. 2020-12-01 [PMID: 33262469] (ICC, Human) ICC Human
T Yamamoto, Y Endo, A Onodera, K Hirahara, HK Asou, T Nakajima, T Kanno, Y Ouchi, S Uematsu, H Nishimasu, O Nureki, DJ Tumes, N Shimojo, T Nakayama DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells Nat Commun, 2018-10-12;9(1):4231. 2018-10-12 [PMID: 30315197] (Flow Cytometry, Mouse) Flow Cytometry Mouse
J Emgård, H Kammoun, B García-Cas, J Chesné, SM Parigi, JM Jacob, HW Cheng, E Evren, S Das, P Czarnewski, N Sleiers, F Melo-Gonza, E Kvedaraite, M Svensson, E Scandella, MR Hepworth, S Huber, B Ludewig, L Peduto, EJ Villablanc, H Veiga-Fern, JP Pereira, RA Flavell, T Willinger Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation Immunity, 2018-01-16;48(1):120-132.e8. 1/16/2018 [PMID: 29343433]
Boyle S, Faulkner J, McColl S, Kochetkova M The chemokine receptor CCR6 facilitates the onset of mammary neoplasia in the MMTV-PyMT mouse model via recruitment of tumor-promoting macrophages. Mol Cancer, 2015-06-06;14(0):115. 2015-06-06 [PMID: 26047945] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Badr G, Sayed A, Abdel-Maksoud M, Mohamed A, El-Amir A, Abdel-Ghaffar F, Al-Quraishy S, Mahmoud M Infection of Female BWF1 Lupus Mice with Malaria Parasite Attenuates B Cell Autoreactivity by Modulating the CXCL12/CXCR4 Axis and Its Downstream Signals PI3K/AKT, NFkappaB and ERK. PLoS ONE, 2015-04-24;10(4):e0125340. 2015-04-24 [PMID: 25909640] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Angkasekwinai P, Sringkarin N, Supasorn O, Fungkrajai M, Wang Y, Chayakulkeeree M, Ngamskulrungroj P, Angkasekwinai N, Pattanapanyasat K Cryptococcus gattii infection dampens Th1 and Th17 responses by attenuating dendritic cell function and pulmonary chemokine expression in the immunocompetent hosts. Infect Immun, 2014-06-30;82(9):3880-90. 2014-06-30 [PMID: 24980974] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Cai Y, Xue F, Fleming C, Yang J, Ding C, Ma Y, Liu M, Zhang H, Zheng J, Xiong N, Yan J Differential developmental requirement and peripheral regulation for dermal Vgamma4 and Vgamma6T17 cells in health and inflammation. Nat Commun, 2014-06-09;5(0):3986. 2014-06-09 [PMID: 24909159] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Show All 19 Publications.

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Bioinformatics

Gene Symbol CCR6
Uniprot