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CCR2 Antibody (890231) [mFluor Violet 450 SE]

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Product Details

Summary
Reactivity RtSpecies Glossary
Applications Flow, CyTOF-ready
Clone
890231
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 450 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB8368U-100UG
Alexa Fluor 405
FAB8368V-100UG
Alexa Fluor 488
FAB8368G-100UG
Alexa Fluor 532
FAB8368X
Alexa Fluor 594
FAB8368T-100UG
Alexa Fluor 647
FAB8368R-025UG
Alexa Fluor 647
FAB8368R-100UG
Alexa Fluor 700
FAB8368N-100UG
Alexa Fluor 750
FAB8368S-100UG
Allophycocyanin
FAB8368A-025UG
Allophycocyanin/Cy7
FAB8368APCCY7
Biotin
FAB8368B
CoraFluor 1
FAB8368CL1
DyLight 350
FAB8368D
DyLight 405
FAB8368E
DyLight 488
FAB8368K
DyLight 550
FAB8368L
DyLight 594
FAB8368M
DyLight 650
FAB8368W
DyLight 680
FAB8368Y
DyLight 755
FAB8368Z
FITC
FAB8368F
HRP
FAB8368H
Janelia Fluor 525
FAB8368JF525
Janelia Fluor 549
FAB8368I
Janelia Fluor 585
FAB8368JF585
Janelia Fluor 635
FAB8368JF635
Janelia Fluor 646
FAB8368J
Janelia Fluor 669
FAB8368JF669
PE/Atto594
FAB8368PEATT594
PE/Cy5.5
FAB8368PECY55
PE/Cy7
FAB8368PECY7
PerCP
FAB8368C
Phycoerythrin
FAB8368P-100UG
Unconjugated
MAB8368
mFluor Violet 500 SE
FAB8368MFV500
mFluor Violet 610 SE
FAB8368MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB8368
Carrier Free
MAB8368
Carrier Free
MAB8368-SP
Carrier Free
FAB8368R-025UG
Carrier Free
FAB8368U-100UG
Carrier Free
FAB8368T-100UG
Carrier Free
FAB8368S-100UG
Carrier Free
FAB8368G-100UG
Carrier Free
FAB8368A-025UG
Carrier Free
FAB8368N-100UG
Carrier Free
FAB8368R-100UG
Carrier Free
FAB8368V-100UG
Carrier Free
FAB8368P-100UG
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CCR2 Antibody (890231) [mFluor Violet 450 SE] Summary

Immunogen
NS0 mouse myeloma cell line transfected with rat CCR2
Accession # O55193
Specificity
Stains rat CCR2 transfectants but not irrelevant transfectants in flow cytometry.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CCR2
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CCR2 Antibody (890231) [mFluor Violet 450 SE]

  • C-C chemokine receptor type 2
  • C-C CKR-2
  • CC-CKR-2
  • CC-CKR-2CKR2B
  • CCR2
  • CCR-2
  • CCR2A
  • CCR2B
  • CD192 antigen
  • CD192
  • chemokine (C-C motif) receptor 2
  • CKR2
  • CKR2A
  • CMKBR2
  • CMKBR2MGC111760
  • FLJ78302
  • MCP-1 receptor
  • MCP-1-R
  • MCP-1-RMGC103828
  • MGC168006
  • Monocyte chemoattractant protein 1 receptor
  • monocyte chemotactic protein 1 receptor

Background

CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CCR2