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CCR2 Antibody (2D8) [FITC]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
2D8
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-35333AF350
Alexa Fluor 405
NBP2-35333AF405
Alexa Fluor 488
NBP2-35333AF488
Alexa Fluor 532
NBP2-35333AF532
Alexa Fluor 594
NBP2-35333AF594
Alexa Fluor 647
NBP2-35333AF647
Alexa Fluor 700
NBP2-35333AF700
Alexa Fluor 750
NBP2-35333AF750
Biotin
NBP2-35333B
CoraFluor 1
NBP2-35333CL1
DyLight 350
NBP2-35333UV
DyLight 405
NBP2-35333V
DyLight 488
NBP2-35333G
DyLight 550
NBP2-35333R
DyLight 594
NBP2-35333DL594
DyLight 650
NBP2-35333C
DyLight 680
NBP2-35333FR
DyLight 755
NBP2-35333IR
HRP
NBP2-35333H
Janelia Fluor 525
NBP2-35333JF525
Janelia Fluor 549
NBP2-35333JF549
Janelia Fluor 585
NBP2-35333JF585
Janelia Fluor 635
NBP2-35333JF635
Janelia Fluor 646
NBP2-35333JF646
Janelia Fluor 669
NBP2-35333JF669
Unconjugated
NBP2-35333
mFluor Violet 450 SE
NBP2-35333MFV450
mFluor Violet 500 SE
NBP2-35333MFV500
mFluor Violet 610 SE
NBP2-35333MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-35333
BSA Free
NBP2-35333SS
BSA Free
NBP2-35333
Azide and BSA Free
NBP2-80622
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CCR2 Antibody (2D8) [FITC] Summary

Immunogen
A synthetic peptide made to an N-terminal portion of the human CCR2 protein (between residues 1-100) [Uniprot: P41597]
Isotype
IgG2b Lambda
Clonality
Monoclonal
Host
Mouse
Gene
CCR2
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for CCR2 Antibody (2D8) [FITC]

  • C-C chemokine receptor type 2
  • C-C CKR-2
  • CC-CKR-2
  • CC-CKR-2CKR2B
  • CCR2
  • CCR-2
  • CCR2A
  • CCR2B
  • CD192 antigen
  • CD192
  • chemokine (C-C motif) receptor 2
  • CKR2
  • CKR2A
  • CMKBR2
  • CMKBR2MGC111760
  • FLJ78302
  • MCP-1 receptor
  • MCP-1-R
  • MCP-1-RMGC103828
  • MGC168006
  • Monocyte chemoattractant protein 1 receptor
  • monocyte chemotactic protein 1 receptor

Background

CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CCR2