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Recombinant Rat CCL17/TARC Protein

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SDS-Page: Rat CCL17/TARC Protein [NBP2-35298]
SDS-Page: Rat CCL17/TARC Protein [NBP2-35298]

Product Details

Summary
Reactivity RtSpecies Glossary
Applications PAGE, Bioactivity
Format
Carrier-Free
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier-Free
NBP2-35298-1mg
Carrier-Free
NBP2-35298-100ug
Carrier-Free
NBP2-35298-500ug
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Recombinant Rat CCL17/TARC Protein Summary

Description
A single non-glycosylated polypeptide chain containing 70 amino acids corresponding to CCL17/TARC Source: E. coli

Uniprot ID: Q9ERE0

Amino Acid Sequence: ARATNVGREC CLDYFKGAIP IRKLVTWFRT SVECPKDAIV FETVQGRLIC TDPKDKHVKK AIRHLKNQRL
Details of Functionality
TARC Protein is fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10 ng/ml.
Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
CCL17
Purity
> 97 % pure by SDS-PAGE and HPLC
Endotoxin Note
Less than 0.1 EU/ug of CCL17/TARC as determined by LAL method.

Applications/Dilutions

Dilutions
  • Bioactivity
  • SDS-Page
Theoretical MW
8.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.
Buffer
Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Preservative
No Preservative
Concentration
LYOPH
Purity
> 97 % pure by SDS-PAGE and HPLC
Reconstitution Instructions
Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL.

Alternate Names for Recombinant Rat CCL17/TARC Protein

  • ABCD-2
  • CC chemokine TARC
  • C-C motif chemokine 17
  • CCL17
  • chemokine (C-C motif) ligand 17
  • MGC138273
  • SCYA17
  • SCYA17MGC138271
  • small inducible cytokine subfamily A (Cys-Cys), member 17
  • Small-inducible cytokine A17
  • T cell-directed CC chemokine
  • TARC
  • TARC/CCL17
  • TARCA-152E5.3
  • Thymus and activation-regulated chemokine

Background

CCL17 also known as thymus and activation-related chemokine (TARC) is encoded by the CCL17 gene located on the chromosome 16. It is expressed by thymus cells constitutively and phytohemagglutinin-stimulated peripheral blood mononuclear cells transiently. CCL17 signals through the chemokine receptors CCR4 and CCR8 and displays chemotactic activity for T lymphocytes and some other leukocytes. It plays an important role in skin diseases such as atopic dermatitis, bullous pemphigoid and mycosis fungoides. CCL17 has approximately 24 - 29 % amino acid sequence identity with RANTES, MIP-1alpha, MIP-1beta, MCP-1, MCP-2, MCP-3 and I-309.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Recombinant Rat
CCL17/TARC Protein
NBP2-35298
Recombinant Rat CCL17/TARC Protein
Species: Rt
Applications: PAGE, Bioactivity

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Bioinformatics

Gene Symbol CCL17