c-Maf Antibody

c-Maf is part of the Maf family of transcription factors that possess a conserved basic region and a leucine zipper domain that mediate DNA and protein-protein binding and plays an important role in tissue-specific gene regulation and cell differentiation. c-Maf is a transcriptional activator of interleukin 4 and 10 in T-cells, and is involved in lens fiber cell differentiation. c-Maf translocation has been observed in human multiple myeloma and may be oncogenic.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 5 of 5.

Publications using NB600-267	Applications	Species
Xie Q, Cvekl A. The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops. J Biol Chem 2011-12-01 [PMID: 21998302]
Katz LS, Gosmain Y, Marthinet E et al. Pax6 regulates the proglucagon processing enzyme PC2 and its chaperone 7B2. Mol Cell Biol 2009-04-01 [PMID: 19223471]
Gosmain Y, Avril I, Mamin A et al. Pax-6 and c-Maf functionally interact with the alpha-cell-specific DNA element G1 in vivo to promote glucagon gene expression. J Biol Chem 2007-11-01 [PMID: 17901057]
Nishimura W, Kondo T, Salameh T et al. A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. Dev Biol 2006-05-01 [PMID: 16580660]
Cao S, Liu J, Song L et al. The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophages. J Immunol 2005-03-01 [PMID: 15749884]

Array NB600-267

• c-Maf Antibodies
• c-Maf ELISA Kits
• c-Maf Proteins