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Angiopoietin-2 Antibody (MM0020-1F29) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity Hu, ChSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
MM0020-1F29
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 525

Order Details

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Angiopoietin-2 Antibody (MM0020-1F29) [Janelia Fluor® 525] Summary

Immunogen
Human recombinant Angiopoietin-2
Specificity
No cross reactivity with human Angiopoietin-1
Isotype
IgG2
Clonality
Monoclonal
Host
Mouse
Gene
ANGPT2
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Chicken data from customer review.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Angiopoietin-2 Antibody (MM0020-1F29) [Janelia Fluor® 525]

  • AGPT2
  • ANG2
  • ANG-2
  • angiopoietin 2
  • Angiopoietin-2
  • angiopoietin-2a
  • angiopoietin-2B
  • angiopoitin 2
  • ANGPT2
  • Tie2-ligand

Background

Angiopoietin 1 and Angiopoietin 2 are important for development of the endothelium, by regulating tyrosine phosphorylation of the membrane receptor Tie 2/Tek. Angiopoietin 2 is only 60% homologous with Angiopoietin 1. Angiopoietin 1 binding to Tie 2/Tek causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding, and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodeling: dorsal aorta and major aortic branches, ovary, placenta and uterus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ANGPT2