Angiopoietin 1 and Angiopoietin 2 are important for development of the endothelium, by regulating tyrosine phosphorylation of the membrane receptor Tie 2/Tek. Angiopoietin 2 is only 60% homologous with Angiopoietin 1. Angiopoietin 1 binding to Tie 2/Tek causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding, and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodeling: dorsal aorta and major aortic branches, ovary, placenta and uterus.
![Western Blot Angiopoietin-2 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Angiopoietin-2_AF623_Western_Blot_9323.jpg)
![Immunohistochemistry Angiopoietin-2 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Angiopoietin-2_AF623_Immunohistochemistry_6884.jpg)
![Immunohistochemistry Angiopoietin-2 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Angiopoietin2_AF623_Immunohistochemistry_17208.jpg)
![Immunohistochemistry Angiopoietin-2 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af623_human-angiopoietin-2-affinity-purified-polyclonal-ab-8220249511440.jpg)
![Immunohistochemistry Angiopoietin-2 Antibody (85816) [Unconjugated]](http://images.novusbio.com/fullsize2/Angiopoietin2_MAB098_Immunohistochemistry_23341.jpg)
![Immunohistochemistry Angiopoietin-2 Antibody (85816) [Unconjugated]](http://images.novusbio.com/fullsize2/Angiopoietin2_MAB098_Immunohistochemistry_24132.jpg)
![Immunohistochemistry Angiopoietin-2 Antibody (85816) [Unconjugated]](http://images.novusbio.com/fullsize2/Angiopoietin2_MAB098_Immunohistochemistry_24133.jpg)
![Sandwich ELISA Angiopoietin-2 Antibody Pair [HRP]](http://images.novusbio.com/fullsize/Angiopoietin-2-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79507-img0001.jpg)
![N/A Angiopoietin-2 [HRP]](http://images.novusbio.com/fullsize2/DATA_Angiopoietin2_DANG20_ELISA_574.jpg)
![N/A Angiopoietin-2 [HRP]](http://images.novusbio.com/fullsize2/Angiopoietin-2_DANG20_ELISA_30.jpg)
![N/A Angiopoietin-2 [Biotin]](http://images.novusbio.com/fullsize2/DATA_Angiopoietin2_DY623_ELISA_2157.jpg)
![N/A Angiopoietin-2 [HRP]](http://images.novusbio.com/fullsize2/DATA_Angiopoietin2_MANG20_ELISA_939.jpg)
![N/A Angiopoietin-2 [HRP]](http://images.novusbio.com/fullsize2/Angiopoietin2_MANG20_ELISA_472.jpg)
![N/A Angiopoietin-2 [HRP]](http://images.novusbio.com/fullsize/mang20_mouse-rat-angiopoietin-2-quantikine-elisa-kit-44202415425036.jpg)
![Binding Activity Angiopoietin-2 [Unconjugated]](http://images.novusbio.com/fullsize2/Angiopoietin2_623AN_3066.jpg)
![Binding Activity Angiopoietin-2 [Unconjugated]](http://images.novusbio.com/fullsize2/Angiopoietin2_623ANCF_3067.jpg)