alpha-Actinin 1 Antibody (OTI7A4)

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: IF/IHC.

Showing Publications 1 - 2 of 2.

Publications using NBP1-48251	Applications	Species
Huang B, Lin C, Wang C, Kao S. Upregulation of heat shock protein 70 and the differential protein expression induced by tumor necrosis factor-alpha enhances migration and inhibits apoptosis of hepatocellular carcinoma cell HepG2. International Journal of Medical sciences. 2017-02-25 [PMID: 28367089] (IF/IHC, Human)	IF/IHC	Human
Shen X, Soibam B, Benham A et al. miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification. Proc. Natl. Acad. Sci. U.S.A. 2016-08-23 [PMID: 27512039] (IF/IHC, Mouse)	IF/IHC	Mouse

Array NBP1-48251

• alpha-Actinin 1 Antibodies
• alpha-Actinin 1 ELISA Kit
• alpha-Actinin 1 Lysate
• alpha-Actinin 1 Proteins