ABCG1 Antibody - BSA Free

ABCG1 (ATP-binding cassette sub-family G member 1) is a member of the ABC superfamily of transporters, specifically the ABCG (White) subfamily, that is characterized by their ABC domain organization (1). The ABC domains are around 180 amino acids (aa) in length and contain three conserved domains: Walker A motif (12 aa), Walker B motif (5 aa), and Signature motif (5 aa) (1, 2). Functional ABC transporters are comprised of two ABCs and two transmembrane domains (TMDs), where each TMD contains six TM alpha-helices (1-3). ABCG1 is considered a "half" transporter because it only has one ABC domain and one TMD (1-3). In order to be functional, ABCG1 and other half transporters can form homodimers or heterodimers (1-3). ABCG1 has a theoretical molecular weight of 102 kDa and is highly expressed in cells including macrophages, lymphocytes, and neurons (2). Additionally, ABCG1 is shown to be highly expressed in lung, kidney, brain, and spleen tissue (2). Specifically, ABCG1 is presented on the cell surface and in intracellular compartments of cholesterol-rich macrophages and, consequently, plays a crucial role in cholesterol regulation and homeostasis (3-5). ABCG1 is involved in the export, or efflux, of cholesterol and phospholipids from macrophages to high density lipoproteins (HDL) for eventual excretion via the liver.

A variety of cardiovascular and cardiometabolic diseases are associated with ABCG1 dysfunction (5-7). Macrophages can become cholesterol-containing foam cells that are generated by the uptake of low-density lipoproteins (LDL), cholesterol esterification, and compromised cholesterol efflux machinery in transporters like ABCG1 and ABCA1 (2, 5, 6, 7). Foam cells are associated with the chronic, inflammatory disease atherosclerosis which is characterized by arterial buildup of plaques that can ultimately lead to cardiovascular disease (5, 6, 7). Additionally, ABCG1 has a critical role in cardiometabolic disorders. Studies have found that diabetic mice have decreased ABCG1 expression (8). Furthermore, loss of ABCG1 in mouse pancreatic beta cells ultimately leads to impaired insulin secretion, suggesting that inhibition or modulation of ABCG1 may contribute to development of diabetes and obesity (8). Finally, other related ATP-binding cassette transporter family members, such as ABCA1 and ABCG5/8, have been associated with genetically-inherited syndromes like Tangier disease, characterized by reduced levels of HDL in the blood, and Sitosterolemia, characterized by elevated plant sterol lipid accumulation in blood and tissues (7). .

Alternate names for ABCG1 includes ABC transporter 8 (ABC8), ATP-binding cassette transporter, anti-, sub-family G (WHITE), homolog of Drosophila white, and MGC34313. .

References

1. Tarling E. J. (2013). Expanding roles of ABCG1 and sterol transport. Current opinion in lipidology. https://doi.org/10.1097/MOL.0b013e32835da122.

2. Tarr, P. T., Tarling, E. J., Bojanic, D. D., Edwards, P. A., & Baldan, A. (2009). Emerging new paradigms for ABCG transporters. Biochimica et biophysica acta.https://doi.org/10.1016/j.bbalip.2009.01.007.

3. Tarling, E. J., & Edwards, P. A. (2011). ATP binding cassette transporter G1 (ABCG1) is an intracellular sterol transporter. Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.1113021108.

4. Phillips M. C. (2014). Molecular mechanisms of cellular cholesterol efflux. The Journal of biological chemistry, 289(35), 24020-24029. https://doi.org/10.1074/jbc.R114.583658.

5. Ouimet, M., Barrett, T. J., & Fisher, E. A. (2019). HDL and Reverse Cholesterol Transport. Circulation research. https://doi.org/10.1161/CIRCRESAHA.119.312617.

6. Yu, X. H., Fu, Y. C., Zhang, D. W., Yin, K., & Tang, C. K. (2013). Foam cells in atherosclerosis. Clinica chimica acta; international journal of clinical chemistry. https://doi.org/10.1016/j.cca.2013.06.006

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 8 confirmed species: Human, Mouse, Rat, Chinese Hamster, Hamster, Monkey, Primate, Rabbit.

We have publications tested in 9 applications: FLOW, ICC/IF, IF/IHC, IHC, IHC-Fr, IHC-P, IP, In vitro, WB.

Showing Publications 1 - 10 of 177. Show All 177 Publications. Collapse Publications.

Publications using NB400-132	Applications	Species
Yalcinkaya M, Fotakis P, Liu W et al. Cholesterol accumulation in macrophages drives NETosis in atherosclerotic plaques via IL-1b secretion Cardiovascular research 2022-12-20 [PMID: 36537208] (WB, Mouse)	WB	Mouse
Bruggmann N Untersuchungen zum ABCA1-/ABCG1-vermittelten Cholesterin-Efflux in humanen Kontroll-und Tangierfibroblasten Thesis 2021-01-01 (WB, Human, Primate)	WB	Human, Primate
Machado J. T. N-acetylcysteine reduces endoplasmic reticulum stress and affects selectively cholesterol efflux from macrophages mediated by ABCA-1 and ABCG-1 in chronic kidney disease. Thesis. 2014-09-01 (WB, Rat)	WB	Rat
Oladosu O, Esobi IC, Powell RR et al. Dissecting the Impact of Vascular Smooth Muscle Cell ABCA1 versus ABCG1 Expression on Cholesterol Efflux and Macrophage-like Cell Transdifferentiation: The Role of SR-BI Journal of cardiovascular development and disease 2023-10-02 [PMID: 37887863] (WB)	WB
Liu S, Zhang Y, Zheng X et al. Sulforaphane Inhibits Foam Cell Formation and Atherosclerosis via Mechanisms Involving the Modulation of Macrophage Cholesterol Transport and the Related Phenotype Nutrients 2023-04-28 [PMID: 37432260] (ICC/IF, IHC-Fr)	ICC/IF, IHC-Fr
Gro beta E, Hilger RA, Schümann FL et al. SAM-Competitive EZH2-Inhibitors Induce Platinum Resistance by EZH2-Independent Induction of ABC-Transporters Cancers 2023-06-03 [PMID: 37297005] (WB, Human)	WB	Human
Wang P, Li M, Gao T et al. Vascular Electrical Stimulation with Wireless, Battery-Free, and Fully Implantable Features Reduces Atherosclerotic Plaque Formation Through Sirt1-Mediated Autophagy Small (Weinheim an der Bergstrasse, Germany) 2023-06-02 [PMID: 37267941] (WB, Mouse)	WB	Mouse
Cao D, Khan Z, Li X et al. Macrophage angiotensin-converting enzyme (ACE) reduces atherosclerosis by increasing PPAR? and fundamentally changing lipid metabolism Cardiovascular research 2023-05-24 [PMID: 37225143] (WB, Mouse)	WB	Mouse
Prasad R, Adu-Agyeiwaah Y, Floyd JL et al. Sustained ACE2 Expression by Probiotic Improves Integrity of Intestinal Lymphatics and Retinopathy in Type 1 Diabetic Model Journal of clinical medicine 2023-02-23 [PMID: 36902558] (IHC-P, Mouse)	IHC-P	Mouse
Ma C, Zhang J, Yang S et al. Astragalus flavone ameliorates atherosclerosis and hepatic steatosis via improving lipid metabolism and inhibition of inflammation in apoE-/- mice Research Square Sep 3 2020
Cassim Bawa FN, Gopoju R, Xu Y et al. Retinoic Acid Receptor Alpha (RARa) in Macrophages Protects from Diet-Induced Atherosclerosis in Mice Cells 2022-10-11 [PMID: 36291054] (WB, Mouse)	WB	Mouse
Xu H, Zheng LX, Chen XS et al. Brain-specific loss of Abcg1 disturbs cholesterol metabolism and aggravates pyroptosis and neurological deficits after traumatic brain injury Brain Pathology 2023-05-01 [PMID: 36271611] (ICC/IF, IHC)	ICC/IF, IHC
Cai Y, Wang Z, Li L et al. Neuropeptide Y regulates cholesterol uptake and efflux in macrophages and promotes foam cell formation Journal of cellular and molecular medicine 2022-09-29 [PMID: 36172879] (WB, Human)	WB	Human
Man B, Hu C, Yang G et al. Berberine attenuates diabetic atherosclerosis via enhancing the interplay between KLF16 and PPAR alpha in ApoE-/- mice Biochemical and Biophysical Research Communications 2022-07-01 [PMID: 35933927] (WB, Mouse) Details: Figure 3E	WB	Mouse
Basu R, Qian Y, Mathes S et al. Growth hormone receptor antagonism downregulates ATP-binding cassette transporters contributing to improved drug efficacy against melanoma and hepatocarcinoma in vivo Frontiers in oncology 2022-07-05 [PMID: 35865483] (WB, Mouse)	WB	Mouse
Xi B, Luo FZ, He B et al. High nuclear ABCG1 expression is a poor predictor for hepatocellular carcinoma patient survival Hepatobiliary & pancreatic diseases international : HBPD INT 2022-06-01 [PMID: 35778316] (IF/IHC, Human)	IF/IHC	Human
Vaisar T, Wang S, Omer M et al. 10,12-conjugated linoleic acid supplementation improves HDL composition and function in mice Journal of lipid research 2022-06-14 [PMID: 35714730] (WB, Mouse)	WB	Mouse
Esobi I, Olanrewaju O, Echesabal-Chen J, Stamatikos A. Utilizing the LoxP-Stop-LoxP System to Control Transgenic ABC-Transporter Expression In Vitro Biomolecules 2022-05-08 [PMID: 35625607]
Zhang X, Rotllan N, Canfran-Duque A et al. Targeted Suppression of miRNA-33 Using pHLIP Improves Atherosclerosis Regression Circulation research 2022-05-09 [PMID: 35534923] (WB, Mouse)	WB	Mouse
Yildirim Z, Baboo S, Hamid SM et al. Intercepting IRE1 kinase-FMRP signaling prevents atherosclerosis progression EMBO molecular medicine 2022-02-22 [PMID: 35191199] (WB, Mouse)	WB	Mouse
Balamurugan K, Medishetti R, Kotha J et al. PHLPP1 promotes neutral lipid accumulation through AMPK/ChREBP-dependent lipid uptake and fatty acid synthesis pathways iScience 2022-02-01 [PMID: 35141506] (WB, Human, Mouse)	WB	Human, Mouse
Shinohata R, Shibakura M, Arao Y et al. A high-fat/high-cholesterol diet, but not high-cholesterol alone, increases free cholesterol and apoE-rich HDL serum levels in rats and upregulates hepatic ABCA1 expression Biochimie 2022-01-24 [PMID: 35085709] (WB, Rat)	WB	Rat
Hueso M, GriNAn R, Mallen A et al. MiR-125b downregulates macrophage scavenger receptor type B1 and reverse cholesterol transport Biomedicine & Pharmacotherapy 2022-02-01 [PMID: 35062066] (WB, Human, Mouse)	WB	Human, Mouse
Kane J, Jansen M, Hendrix S et al. Anti-Galectin-2 antibody treatment reduces atherosclerotic plaque size and alters macrophage polarity Thrombosis and haemostasis 2021-12-01 [PMID: 34852377] (IF/IHC, Mouse)	IF/IHC	Mouse
Zhang X, McDonald JG, Aryal B Et al. Desmosterol suppresses macrophage inflammasome activation and protects against vascular inflammation and atherosclerosis Proceedings of the National Academy of Sciences of the United States of America 2021-11-23 [PMID: 34782454] (WB, Mouse)	WB	Mouse
Kang CM, Li WK, Yu KW Et al. Long non coding RNA AL355711 promotes smooth muscle cell migration through the ABCG1/MMP3 pathway International journal of molecular medicine 2021-12-01 [PMID: 34608503] (WB)	WB
Sun Y, Wang J, Long T Et al. Molecular basis of cholesterol efflux via ABCG subfamily transporters Proceedings of the National Academy of Sciences of the United States of America 2021-08-24 [PMID: 34404721] (WB, Human)	WB	Human
Wang H, Zhang P, Chen X Et Al. Activin a inhibits foam cell formation and up-regulates ABCA1 and ABCG1 expression through Alk4-Smad signaling pathway in RAW 264.7 macrophages Steroids 2021-07-06 [PMID: 34237315]
Ram�rez CM, Torrecilla-Parra M, Pardo-Marqu�s V et al. Crosstalk Between LXR and Caveolin-1 Signaling Supports Cholesterol Efflux and Anti-Inflammatory�Pathways�in Macrophages Front Endocrinol (Lausanne) 2021-05-27 [PMID: 34122329]
Zhang S, Li Z, Zhang Y et al. Ketone Body 3 Hydroxybutyrate Ameliorates Atherosclerosis via Receptor Gpr109a Mediated Calcium Influx Advanced Science 2021-03-01 [PMID: 33977048] (WB, Mouse)	WB	Mouse
Tsui PF, Chern CY, Lien CF et al. An octimibate derivative, Oxa17, enhances cholesterol efflux and exerts anti-inflammatory and atheroprotective effects in experimental atherosclerosis Biochemical pharmacology 2021-04-23 [PMID: 33895158]
Esobi IC, Barksdale C, Heard-Tate C et al. MOVAS Cells: A Versatile Cell Line for Studying Vascular Smooth Muscle Cell Cholesterol Metabolism Lipids 2021-04-21 [PMID: 33881166]
Liu W, Liu J, Xing S et al. The benzoate plant metabolite ethyl gallate prevents cellular- and vascular-lipid accumulation in experimental models of atherosclerosis Biochemical and biophysical research communications 2021-06-04 [PMID: 33839416]
Sun R, Fang P, Jiang J et al. Insulin Rescued MCP-1-Suppressed Cholesterol Efflux to Large HDL2 Particles via ABCA1, ABCG1, SR-BI and PI3K/Akt Activation in Adipocytes Cardiovascular drugs and therapy 2021-03-19 [PMID: 33740174]
Price NL, Zhang X, Fernández-Tussy P, et al. Loss of hepatic miR-33 improves metabolic homeostasis and liver function without altering body weight or atherosclerosis Proceedings of the National Academy of Sciences of the United States of America 2021-02-02 [PMID: 33495342] (WB, Mouse)	WB	Mouse
Hou X, Zhang C, Wang L, Wang K Natural Piperine Improves Lipid Metabolic Profile of High-Fat Diet-Fed Mice by Upregulating SR-B1 and ABCG8 Transporters Journal of natural products 2021-01-25 [PMID: 33492139]
Ma C, Zhang J, Yang S et al. Astragalus Flavone Ameliorates Atherosclerosis and Hepatic Steatosis Via Inhibiting Lipid-Disorder and Inflammation in apoE-/- Mice Frontiers in Pharmacology 2020-12-14 [PMID: 33381046] (WB, Mouse)	WB	Mouse
Ren Q, Xie X, Tang Y et al. Methyl tertiary-butyl ether inhibits THP-1 macrophage cholesterol efflux in vitro and accelerates atherosclerosis in ApoE-deficient mice in vivo J Environ Sci (China) 2020-12-18 [PMID: 33334519]
Qian Y, Basu R, Mathes SC et al. Growth Hormone Upregulates Mediators of Melanoma Drug Efflux and Epithelial-to-Mesenchymal Transition In Vitro and In Vivo Cancers 2020-12-04 [PMID: 33291663] (WB, Human, Mouse)	WB	Human, Mouse
Alsina-Sanchis, E, MUlfarth, R Et al. Intraperitoneal Oil Application Causes Local Inflammation with Depletion of Resident Peritoneal Macrophages. Mol Cancer Res 2021-02-01 [PMID: 33139505] (WB, Human)	WB	Human
Shang Y, Ma C, Zhang J et al. Bifunctional supramolecular nanofiber inhibits atherosclerosis by enhancing plaque stability and anti-inflammation in apoE-/- mice Theranostics 2020-08-13 [PMID: 32929345] (WB, Mouse)	WB	Mouse
Ohkawa, R, Low, H Et al. Cholesterol transport between red blood cells and lipoproteins contributes to cholesterol metabolism in blood. J Lipid Res 2020-12-01 [PMID: 32907987] (WB, Mouse)	WB	Mouse
A Po, A Citarella, G Catanzaro, ZM Besharat, S Trocchiane, F Gianno, C Sabato, M Moretti, E De Smaele, A Vacca, ME Fiori, E Ferretti Hedgehog-GLI signalling promotes chemoresistance through the regulation of ABC transporters in colorectal cancer cells Sci Rep, 2020-08-19;10(1):13988. 2020-08-19 [PMID: 32814794] (WB, Human)	WB	Human
Barilla S, Liang N, Mileti E et al. Loss of G protein pathway suppressor 2 in human adipocytes triggers lipid remodeling through upregulation of ATP binding cassette subfamily G member 1 Mol Metab 2020-08-13 [PMID: 32798719] (WB, Human)	WB	Human
Donadon M, Torzilli G, Cortese N et al. Macrophage morphology correlates with single-cell diversity and prognosis in colorectal liver metastasis J. Exp. Med. 2020-11-02 [PMID: 32785653] (FLOW, Human)	FLOW	Human
Gao Q, Wei A, Chen F et al. Enhancing PPAR gamma by HDAC inhibition reduces foam cell formation and atherosclerosis in ApoE deficient mice Pharmacological Research 2020-07-01 [PMID: 32621955] (WB, Mouse)	WB	Mouse
Werkman IL, KOvilein J, de Jonge JC, Baron W Impairing committed cholesterol biosynthesis in white matter astrocytes, but not grey matter astrocytes, enhances in vitro myelination J. Neurochem. 2020-06-30 [PMID: 32602556] (WB, Rat)	WB	Rat
Chen LW, Tsai MC, Chern CY et al. A chalcone derivative, 1m-6, exhibits atheroprotective effects by increasing cholesterol efflux and reducing inflammation-induced endothelial dysfunction Br. J. Pharmacol. 2020-06-24 [PMID: 32579243]
Wang D, Hiebl V, Schachner D et al. Soraphen A enhances macrophage cholesterol efflux via indirect LXR activation and ABCA1 upregulation Biochem. Pharmacol. 2020-05-08 [PMID: 32437644] (WB, Human)	WB	Human
Marshall J, Courage E, Elliott R et al. THP-1 Macrophage Cholesterol Efflux Is Impaired by Palmitoleate Through Akt Activation PLoS One. 2020-05-21 [PMID: 32437392] (WB, Human)	WB	Human
Shen CY, Wang TX, Jiang JG et al. Bergaptol from blossoms of Citrus aurantium L. var. amara Engl inhibits LPS-induced inflammatory responses and ox-LDL-induced lipid deposition Food Funct 2020-05-20 [PMID: 32432251]
Salonurmi T, Nabil H, Ronkainen J et Al. 4 beta-Hydroxycholesterol Signals From the Liver to Regulate Peripheral Cholesterol Transporters Front. Pharmacol. 2020-03-27 [PMID: 32292343] (WB, Rat)	WB	Rat
Koga M, Kanaoka Y, Inada K et al. Hesperidin blocks varenicline-aggravated atherosclerotic plaque formation in apolipoprotein E knockout mice by downregulating net uptake of oxidized low-density lipoprotein in macrophages J. Pharmacol. Sci. 2020-02-28 [PMID: 32173266] (WB, Mouse)	WB	Mouse
Guo Y MicroRNA-205-5p Promotes Unstable Atherosclerotic Plaque Formation In Vivo Cardiovasc Drugs Ther 2020-02-08 [PMID: 32034643] (Mouse)		Mouse
Koga M, Kanaoka Y, Okamoto M et al. Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression J. Pharmacol. Sci. 2019-11-14 [PMID: 31771811] (WB, Mouse)	WB	Mouse
Xu Y, Xu Y, Zhu Y et al. Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis Mol. Ther. 2019-09-12 [PMID: 31604677]
Urano Y, Ho Vo DK, Hirofumi A, Noguchi N 24(S)-Hydroxycholesterol induces ER dysfunction-mediated unconventional cell death Cell Death Discov 2019-07-05 [PMID: 31285856] (WB, Human)	WB	Human
Wu A, Grela E, Woojtowicz K, et al. ABCA1 transporter reduces amphotericin B cytotoxicity in mammalian cells Cell. Mol. Life Sci. 2019-05-27 [PMID: 31134303] (WB, Chinese Hamster)	WB	Chinese Hamster
Pasca AM, Park JY, Shin HW et al. Cyclodextrin Ameliorates the Progression of Atherosclerosis via Increasing High-Density Lipoprotein Cholesterol Plasma Levels and Anti-inflammatory Effects in Rabbits J. Cardiovasc. Pharmacol. 2019-05-01 [PMID: 30855405]
Sedgeman LR, Beysen C, Ramirez Solano MA et al. Beta cell secretion of miR-375 to HDL is inversely associated with insulin secretion Sci Rep 2019-03-07 [PMID: 30846744] (WB, Mouse)	WB	Mouse
Yuan C, Guo X, Zhou Q et al. OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing beta-amyloid clearance in APP/PS1 mice. Biochim Biophys Acta Mol Basis Dis 2019-01-01 [PMID: 30389579] (Mouse)		Mouse
Nishino T, Horie T, Baba O et al. SREBF1/MicroRNA-33b Axis Exhibits Potent Effect on Unstable Atherosclerotic Plaque Formation In Vivo Arteriosclerosis, Thrombosis, and Vascular Biology [PMID: 30354203] (WB, Mouse)	WB	Mouse
Harris MT, Hussain SS, Inouye CM et al. Reinterpretation of the localization of the ATP binding cassette transporter ABCG1 in insulin-secreting cells and insights regarding its trafficking and function PLoS One. 2018-09-19 [PMID: 30235209] (IP, Rat)	IP	Rat
Qian K, Feng L, Sun Y et al. Overexpression of Salusin-a Inhibits Vascular Intimal Hyperplasia in an Atherosclerotic Rabbit Model. BioMed Research International 2018-07-12 [PMID: 30105261] (WB, Rabbit)	WB	Rabbit
Wang L, Eftekhari P, Schachner D et al. Novel interactomics approach identifies ABCA1 as direct target of evodiamine, which increases macrophage cholesterol efflux. Sci Rep. 2018-07-23 [PMID: 30038271] (WB, Human)	WB	Human
Sonett J, Goldklang M, Sklepkiewicz P et al. A critical role for ABC transporters in persistent lung inflammation in the development of emphysema after smoke exposure. FASEB J 2018-06-15 [PMID: 29906247] (Mouse)		Mouse
Ying F, Cai Y, Wong HK et al. EP4 emerges as a novel regulator of bile acid synthesis and its activation protects against hypercholesterolemia Biochim Biophys Acta Mol Cell Biol Lipids. [PMID: 29890224] (WB, Mouse)	WB	Mouse
Wang D, Hiebl V, Ladurner A et al. 6-Dihydroparadol, a Ginger Constituent, Enhances Cholesterol Efflux from THP-1-Derived Macrophages. Mol Nutr Food Res 2018-05-26 [PMID: 29802792] (Human)		Human
Li Y, Shen S, Ding S, Wang L. Toll-like receptor 2 downregulates the cholesterol efflux by activating the nuclear factor‑kappa B pathway in macrophages and may be a potential therapeutic target for the prevention of atherosclerosis Experimental and Therapeutic Medicine 2017-10-31 [PMID: 29375683] (WB, Human)	WB	Human
Cuffe H, Liu M, Key CC et al. Targeted Deletion of Adipocyte Abca1 (ATP-Binding Cassette Transporter A1) Impairs Diet-Induced Obesity Arterioscler. Thromb. Vasc. Biol. 2018-01-18 [PMID: 29348118] (Mouse)		Mouse
Canfran-Duque A, Rotllan N, Zhang X et al. Macrophage deficiency of miR-21 promotes apoptosis, plaque necrosis, and vascular inflammation during atherogenesis EMBO Mol Med 2017-07-03 [PMID: 28674080] (WB, Mouse)	WB	Mouse
Liu S, Zhang Y, Zheng X et al. Sulforaphane Inhibits Foam Cell Formation and Atherosclerosis via Mechanisms Involving the Modulation of Macrophage Cholesterol Transport and the Related Phenotype Nutrients 2023-04-28 (IHC-Fr, Mouse) Details: 1:100 dilution	IHC-Fr	Mouse
de Aguiar Vallim TQ, Lee E, Merriott DJ et al. ABCG1 regulates pulmonary surfactant metabolism in mice and men. J. Lipid Res. 2017-03-06 [PMID: 28264879]
Mariani MM, Malm T, Lamb R et al. Neuronally-directed effects of RXR activation in a mouse model of Alzheimer's disease. Sci Rep. 2017-02-16 [PMID: 28205585] (WB, Mouse)	WB	Mouse
Jiang M, Li X. Activation of PPARgamma does not contribute to macrophage ABCA1 expression and ABCA1-mediated cholesterol efflux to apoAI. Biochem. Biophys. Res. Commun. 2016-11-24 [PMID: 27890613] (Mouse)		Mouse
Wang L, Palme V, Rotter S et al. Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP-1-derived macrophages. Mol Nutr Food Res. 2016-11-15 [PMID: 27862930] (WB, Human)	WB	Human
Cheng HY, Gaddis DE, Wu R et al. Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis. J. Clin. Invest. 2016-09-01 [PMID: 27482882] (WB, Mouse)	WB	Mouse
Lai L, Azzam KM, Lin W et al. MicroRNA-33 regulates the innate immune response via ATP Binding Cassette transporter-mediated remodeling of membrane microdomains. J. Biol. Chem. [PMID: 27471270] (WB, Mouse)	WB	Mouse
Aryal B, Rotllan N, Araldi E et al. ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression. Nat Commun. 2016-07-27 [PMID: 27460411] (WB, Mouse)	WB	Mouse
Miroshnikova VV, Panteleeva AA, Bazhenova EA et al. [Regulation of ABCA1 and ABCG1 gene expression in the intraabdominal adipose tissue] Biomeditsinskaya Khimiya 2016-07-16 [PMID: 27420620]
Mostafa A, Hamdy N, Abdel-Rahman S, El-Mesallamy H. Effect of vildagliptin and pravastatin combination on cholesterol efflux in adipocytes. IUBMB Life. [PMID: 27251372] (WB, Mouse)	WB	Mouse
Tarling EJ, Edwards PA. Intracellular Localization of Endogenous Mouse ABCG1 Is Mimicked by Both ABCG1-L550 and ABCG1-P550. Arterioscler. Thromb. Vasc. Biol. 2016-05-26 [PMID: 27230131] (ICC/IF, WB, Monkey, Mouse, Chinese Hamster)	ICC/IF, WB	Monkey, Mouse, Chinese Hamster
Westerterp M, Tsuchiya K et al. Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Endothelial Cells Accelerates Atherosclerosis in Mice. Arterioscler Thromb Vasc Biol 2016-01-07 [PMID: 27199450] (WB, Mouse)	WB	Mouse
Zhang X, Hu J, Zhong L et al. Quercetin stabilizes apolipoprotein E and reduces brain Abeta levels in amyloid model mice. Neuropharmacology. 2016-04-22 [PMID: 27114256] (WB, Mouse)	WB	Mouse
Leng S, Iwanowycz S, Saaoud F et al. Ursolic acid enhances macrophage autophagy and attenuates atherogenesis. J. Lipid Res. 2016-04-10 [PMID: 27063951] (WB, Mouse)	WB	Mouse
Shi H, Mao X, Zhong Y et al. Lanatoside C Promotes Foam Cell Formation and Atherosclerosis Sci Rep 2016-01-29 [PMID: 26821916] (WB, Mouse)	WB	Mouse
Mostafa AM, Hamdy NM, El-Mesallamy HO, Abdel-Rahman SZ. Glucagon-like peptide 1 (GLP-1)-based therapy upregulate LXR-ABCA1/ABCG1 cascade in adipocytes. Biochem. Biophys. Res. Commun. 2015-11-18 [PMID: 26603933]
Matsuo K, Yamamoto S, Wakamatsu T et al. Increased Proinflammatory Cytokine Production and Decreased Cholesterol Efflux Due to Downregulation of ABCG1 in Macrophages Exposed to Indoxyl Sulfate. Toxins (Basel). 2015-08-20 [PMID: 26287243] (WB, Human) Details: ABCG1 antibody was used at 1:1000 dilution for WB analysis of lysates from THP-1 cells that were exposed to 1 mM indoxyl sulfate for differentiation for 24 hours (Figure 2).	WB	Human
Daffu G, Shen X, Senatus L et al. RAGE Suppresses ABCG1-Mediated Macrophage Cholesterol Efflux in Diabetes. Diabetes 2015-12-01 [PMID: 26253613]
Lee Tzong-Shyuan, Lu Kuo-Yun, Yu Yuan-Bin et al. B Common Receptor Mediates Erythropoietin-Conferred Protection on OxLDL-Induced Lipid Accumulation and Inflammation in Macrophages. Mediators of Inflammation 2015-01-01 [PMID: 26101463] (IF/IHC, Mouse)	IF/IHC	Mouse
De Boussac H, Maqdasy S, Trousson A et al. Enolase is regulated by Liver X Receptors Steroids. 2015-02-21 [PMID: 25708389] (WB, Mouse)	WB	Mouse
Kuo Cheng-Hsiang, Leon Lorraine, Chung Eun Ji et al. Inhibition of atherosclerosis-promoting microRNAs via targeted polyelectrolyte complex micelles. J Mater Chem B Mater Biol Med. 2014-12-14 [PMID: 25685357]
Park SH, Paek JH, Shin D et al. Purple perilla extracts with alpha-asarone enhance cholesterol efflux from oxidized LDL-exposed macrophages Int. J. Mol. Med. 2015-02-12 [PMID: 25673178] (WB, Mouse)	WB	Mouse
Du X M, Kim M J et al. HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export. Circ Res 2015-03-27 [PMID: 25589556] (WB, Human)	WB	Human
The expression of ABCG1 transporter gene in peripheral blood mononuclear cells of patients with atherosclerosis. Miroshnikova VV, Demina EP, Mayorov NV Tsitologiia 2005-07-06 [PMID: 25509420]
Zheng W, Mast N, Saadane A, Pikuleva Ia. Pathways of cholesterol homeostasis in mouse retina responsive to dietary and pharmacologic treatments. J. Lipid Res. 2014-10-07 [PMID: 25293590] (IF/IHC, Mouse)	IF/IHC	Mouse
Frisdal E, Lay SL, Hooton H et al. Adipocyte Atp-Binding Cassette G1 Promotes Triglyceride Storage, Fat Mass Growth And Human Obesity. Diabetes. 2014-09-23 [PMID: 25249572]
Tai LM, Koster KP, Luo J et al. Amyloid-b Pathology and APOE Genotype Modulate Retinoid X Receptor Agonist Activity in vivo. J Biol Chem. 2014-09-12 [PMID: 25217640]
Horie Takahiro, Nishino Tomohiro, Baba Osamu et al. MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo. Sci Rep. 2014-06-16 [PMID: 24931346] (Mouse)		Mouse
Du RH, Qin SY, Shi LS et al. Fumigaclavine C activates PPARgamma pathway and attenuates atherogenesis in ApoE-deficient mice. Atherosclerosis 2014-03-05 [PMID: 24637412] (WB, Mouse)	WB	Mouse
Okabe A, Urano Y, Itoh S et al. Adaptive responses induced by 24S-hydroxycholesterol through liver X receptor pathway reduce 7-ketocholesterol-caused neuronal cell death. Redox Biol 2013-12-04 [PMID: 24371802] (WB, Human)	WB	Human
Yu F, Du F, Wang Y et al. Bone Marrow Deficiency of MCPIP1 Results in Severe Multi-Organ Inflammation but Diminishes Atherogenesis in Hyperlipidemic Mice. PLoS One. 2013-11-06 [PMID: 24223214] (WB, Mouse)	WB	Mouse
Nicod N, Parker RS. Vitamin E secretion by Caco-2 monolayers to APOA1, but not to HDL, is vitamer selective. J Nutr. 2013-10-01 [PMID: 23946344] (WB, Human)	WB	Human
Daniil G, Zannis VI, Chroni A. Effect of apoA-I Mutations in the Capacity of Reconstituted HDL to Promote ABCG1-Mediated Cholesterol Efflux. PLoS One 2013-06-27 [PMID: 23826352] (WB, Human, Mouse)	WB	Human, Mouse
Zhou MS, Chadipiralla K, Mendez AJ et al. Nicotine potentiates proatherogenic effects of oxLDL by stimulating and upregulating macrophage CD36 signaling. Am J Physiol Heart Circ Physiol. 2013-08-01 [PMID: 23748423] (WB, Human)	WB	Human
Nakaya K, Ayaori M, Uto-Kondo H et al. Overexpression of stearoyl-coenzyme A desaturase 1 in macrophages promotes reverse cholesterol transport. Biochim Biophys Acta 2013-08-01 [PMID: 23747827] (WB, Mouse)	WB	Mouse
Fang L, Choi SH, Baek JS et al. Control of angiogenesis by AIBP-mediated cholesterol efflux. Nature 2013-06-06 [PMID: 23719382] (WB, Human)	WB	Human
Doddapattar P, Radovic B, Patankar JV et al. Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice. Mol Nutr Food Res 2013-05-03 [PMID: 23650230] (WB, Mouse)	WB	Mouse
Mulay V, Wood P, Manetsch M et al. Inhibition of Mitogen-Activated Protein Kinase Erk1/2 Promotes Protein Degradation of ATP Binding Cassette Transporters A1 and G1 in CHO and HuH7 Cells. PLoS One 2013-04-25 [PMID: 23634230] (WB, Hamster, Human)	WB	Hamster, Human
de Beer MC, Wroblewski JM, Noffsinger VP et al. The Impairment of Macrophage-to-Feces Reverse Cholesterol Transport during Inflammation Does Not Depend on Serum Amyloid A. J Lipids 2013-01-01 [PMID: 23431457] (WB, Mouse)	WB	Mouse
Huang CX, Zhang YL, Wang Jf et al. MCP-1 impacts RCT by repressing ABCA1, ABCG1, and SR-BI through PI3K/Akt posttranslational regulation in HepG2 cells. J Lipid Res 2013-05-01 [PMID: 23402987]
Gu HM, Li G, Gao X, Berthiaume LG, Zhang DW. Characterization of palmitoylation of ATP binding cassette transporter G1: effect on protein trafficking and function. Biochim Biophys Acta 2013-02-03 [PMID: 23388354]
El Roz A, Bard JM, Huvelin JM, Nazih H. The anti-proliferative and pro-apoptotic effects of the trans9,trans11 conjugated linoleic acid isomer on MCF-7 breast cancer cells are associated with LXR activation. Prostaglandins Leukot Essent Fatty Acids 2013-01-31 [PMID: 23375583] (WB, Human)	WB	Human
Khan OM, Akula MK, Skalen K et al. Targeting GGTase-I Activates RHOA, Increases Macrophage Reverse Cholesterol Transport, and Reduces Atherosclerosis in Mice. Circulation 2013-02-19 [PMID: 23334894] (WB, Mouse)	WB	Mouse
Horie T, Baba O, Kuwabara Y et al. MicroRNA-33 Deficiency Reduces the Progression of Atherosclerotic Plaque in ApoE?/? Mice. J Am Heart Assoc 2012-01-01 [PMID: 23316322] (WB, Mouse)	WB	Mouse
Ishibashi M, Filomenko R, Rebe C et al. Knock-down of the oxysterol receptor LXRalpha impairs cholesterol efflux in human primary macrophages: lack of compensation by LXRbeta activation. Biochem Pharmacol. 2013-07-01 [PMID: 23313547] (WB, Human)	WB	Human
Munch G, Bultmann A, Li Z et al. Overexpression of ABCG1 protein attenuates arteriosclerosis and endothelial dysfunction in atherosclerotic rabbits. Heart Int 2012-06-05 [PMID: 23185679] (ICC/IF, Rabbit)	ICC/IF	Rabbit
Beyea, M, Reaume, S, Sawyez, C et al. The Oxysterol 24(S),25-Epoxycholesterol Attenuates Human Smooth Muscle-Derived Foam Cell Formation Via Reduced Low-Density Lipoprotein Uptake and Enhanced Cholesterol Efflux J Am Heart Assoc 2012-11-07 [PMID: 23130136]
Maitra U, Li L. Molecular mechanisms responsible for the reduced expression of cholesterol transporters from macrophages by low-dose endotoxin Arterioscler Thromb Vasc Biol 2013-01-01 [PMID: 23117655] (WB, Mouse)	WB	Mouse
Chen J, Zhang X, Kusumo H et al. Cholesterol efflux is differentially regulated in neurons and astrocytes: Implications for brain cholesterol homeostasis Biochim Biophys Acta 2012-09-23 [PMID: 23010475] (WB, Rat)	WB	Rat
Marko L, Paragh G, Ugocsai P et al. Keratinocyte ATP binding cassette transporter expression is regulated by ultraviolet light J Photochem Photobiol B 2012-11-05 [PMID: 22982209] (IF/IHC, WB, Human)	IF/IHC, WB	Human
Gelissen IC, Sharpe LJ, Sandoval C et al. Protein kinase A modulates the activity of a major human isoform of ABCG1 J Lipid Res 2012-10-01 [PMID: 22872754]
Wang SH, Yuan SG, Peng DQ, Zhao SP. HDL and ApoA-I Inhibit Antigen Presentation-mediated T Cell Activation by Disrupting Lipid Rafts in Antigen Presenting Cells Atherosclerosis 2012-07-27 [PMID: 22862966] (WB, Mouse)	WB	Mouse
Iizuka M, Ayaori M, Uto-Kondo H et al. Astaxanthin enhances ATP-binding cassette transporter A1/G1 expressions and cholesterol efflux from macrophages J Nutr Sci Vitaminol 2012-01-01 [PMID: 22790567] (WB, Human, Mouse)	WB	Human, Mouse
Olivier M, Tanck MW, Out R et al. Human ATP-binding cassette G1 controls macrophage lipoprotein lipase bioavailability and promotes foam cell formation. Arterioscler Thromb Vasc Biol 2012-09-01 [PMID: 22772754]
El Roz A, Bard JM, Huvelin JM, Nazih H. LXR Agonists and ABCG1-dependent Cholesterol Efflux in MCF-7 Breast Cancer Cells: Relation to Proliferation and Apoptosis Anticancer Res 2012-07-01 [PMID: 22753765]
Yasuyo Okada, Kiyomi Ueyama, Jyun-ichi Nishikawa, Masanori Semma, Atsushi Ichikawa. Effect of 6-O-alpha-maltosyl-beta cyclodextrin and its cholesterol inclusion complex on cellular cholesterol levels and ABCA1 and ABCG1 expression in mouse mastocytoma P-815 cells, . Carbohydrate Research, 10.1016/j.carres.2012.04.019. 2012-01-01 [PMID: 22677519] (WB, Mouse)	WB	Mouse
Reboulleau A, Robert V, Vedie B et al. Involvement of cholesterol efflux pathway in the control of cardiomyocytes cholesterol homeostasis. Journal of Molecular and Cellular Cardiology. 2012-06-03 [PMID: 22668787] (WB, Rat)	WB	Rat
Zhao JF, Ching LC, Huang YC, Chen CY, Chiang AN, Kou YR, Shyue SK, Lee TS. Molecular mechanism of curcumin on the suppression of cholesterol accumulation in macrophage foam cells and atherosclerosis. Mol Nutr Food Res;56(5):691-701. 2012-05-01 [PMID: 22648616] (WB, Mouse)	WB	Mouse
Tang S-L, Chen W-J, Yin K, et el. PAPP-A Negatively Regulates ABCA1, ABCG1 and SR-B1 Expression by inhibiting LXR alpha through the IGF-I-mediated signaling pathway Atherosclerosis 2012-06-01 [PMID: 22503545] (WB, Human)	WB	Human
Cui W, SunY ,Wang Z et al. Liver X receptor activation attenuates inflammatory response and protects cholinergic neurons in APP/PS1 transgenic mice Neuroscience 2012-03-05 [PMID: 22425753] (WB, Mouse)	WB	Mouse
Meurs I, Calpe-Berdiel L, Habets KLL, Zhao Y, Korporaal SJA et al. Effects of Deletion of Macrophage ABCA7 on Lipid Metabolism and the Development of Atherosclerosis in the Presence and Absence of ABCA1 PLoS ONE 2012-01-01 [PMID: 22403608] (WB, Mouse)	WB	Mouse
Morbitzer D, Namgaladze D, Brune B. Phospholipase A(2)-Modified Low-Density Lipoprotein Activates Liver X Receptor in Human Macrophages Cell Biochem Biophys 2012-02-26 [PMID: 22367754] (WB, Human)	WB	Human
Ayaori M, Yakushiji E, Ogura M, Nakaya K, Hisada T, Uto-Kondo H, Takiguchi S, Terao Y, Sasaki M, Komatsu T, Iizuka M, Yogo M, Uehara Y, Kagechika H, Nakanishi T, Ikewaki K. Retinoic acid receptor agonists regulate expression of ATP-binding cassette transporter G1 in macrophages. Biochim Biophys Acta;1821(4):561-572. 2012-02-14 [PMID: 22353356]
Morales CR, Ni X, Smith CE et al. ABCA17 mediates sterol efflux from mouse spermatozoa plasma membranes. Histol Histopathol 27(3). 2012-03-01 [PMID: 22237709] (In vitro, Mouse)	In vitro	Mouse
Ku CS, Park Y, Coleman SL, Lee J. Unsaturated fatty acids repress expression of ATP binding cassette transporter A1 and G1 in RAW 264. 7 macrophages. The Journal of Nutritional Biochemistry. 2011-12-29 [PMID: 22209005]
Ji A, Wroblewski JM, Cai L et al. Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI. J Lipid Res 2012-03-01 [PMID: 22190590] (WB)	WB
Edgel KA, McMillen TS, Wei H et al. Obesity and weight loss result in increased adipose tissue ABCG1 expression in db/db mice. Biochim Biophys Acta 2012-03-01 [PMID: 22179025]
Tallada Iborra R, Machado-Lima A, Castilho G et al. Advanced Glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expression of ABCA-1 and ABCG-1. Lipids in Health and Disease;10(1):172. 2011-09-29 [PMID: 21957962]
Nagashima M, Watanabe T, Terasaki M et al. Native incretins prevent the development of atherosclerotic lesions in apolipoprotein E knockout mice Diabetologia 2011-10-01 [PMID: 21786155] (WB, Mouse)	WB	Mouse
Corcoran MP, Lichtenstein AH, Meydani M et al. The effect of 17{beta}-estradiol on cholesterol content in human macrophages is influenced by the lipoprotein milieu. J Mol Endocrinol. 2011-06-06 [PMID: 21646386] (WB, Human)	WB	Human
Chen J, Costa LG, Guizzetti M. Retinoic acid isomers up-regulate ATP binding cassette a1 and g1 and cholesterol efflux in rat astrocytes: implications for their therapeutic and teratogenic effects. J Pharmacol Exp Ther;338(3):870-8. 2011-09-01 [PMID: 21628419]
Ji A, Meyer JM, Cai L et al. Scavenger receptor SR-BI in macrophage lipid metabolism. Atherosclerosis. 2011-04-08 [PMID: 21481393]
Wong BXW, Kyle RA, Croft KD et al. Modulation of Macrophage Fatty Acid Content and Composition by Exposure to Dyslipidemic Serum in Vitro. Lipids;46(4):371-80. 2011-04-01 [PMID: 21286835]
Law RH, Lukoyanova N, Voskoboinik I et al. The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature 2010-11-18 [PMID: 21037563] (WB)	WB
Truong TQ, Aubin D, Falstrault L et al. SR-BI, CD36, and caveolin-1 contribute positively to cholesterol efflux in hepatic cells. Cell Biochem Funct 2010-08-01 [PMID: 20629037]
Aye IL, Waddell BJ, Mark PJ, Keelan JA. Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity. Biochim Biophys Acta 2010-09-01 [PMID: 20570635] (Human)		Human
Uto-Kondo H, Ayaori M, Ogura M et al. Coffee consumption enhances high-density lipoprotein-mediated cholesterol efflux in macrophages. Circ Res;106(4):779-87. 2010-03-05 [PMID: 20075335] (WB, Mouse)	WB	Mouse
Larrede S, Quinn C M et al. Stimulation of cholesterol efflux by LXR agonists in cholesterol-loaded human macrophages is ABCA1-dependent but ABCG1-independent. Arterioscler Thromb Vasc Biol 2009-01-11 [PMID: 19729607] (WB, Human)	WB	Human
Nagelin MH, Srinivasan S, Nadler JL et al. Murine 12/15-lipoxygenase regulates ATP-binding cassette transporter G1 protein degradation through p38- and JNK2-dependent pathways. J Biol Chem;284(45):31303-14. 2009-11-06 [PMID: 19713213]
Welch C, Santra MK, El-Assaad W et al. Identification of a Protein, G0S2, That Lacks Bcl-2 Homology Domains Interacts with Antagonizes Bcl-2. Cancer Res 2009:0008-5472CAN-0009-0128. [PMID: 19706769]
Xu G, Watanabe T, Iso Y et al. Preventive Effects of Heregulin-{beta}1 on Macrophage Foam Cell Formation Atherosclerosis. Circ Res;105(5):500-510. 2009-01-01 [PMID: 19644050]
Hongo S, Watanabe T, Arita S et al. Leptin modulates ACAT1 expression and cholesterol efflux from human macrophages. Am J Physiol Cell Physiol 2009-08-01 [PMID: 19625677] (WB, Human)	WB	Human
Liu J, Huan C, Chakraborty M et al. Macrophage Sphingomyelin Synthase 2 Deficiency Decreases Atherosclerosis in Mice. Circ Res;105(3):295-303. 2009-01-01 [PMID: 19590047]
Ronis MJ et al. Dietary soy protein isolate attenuates metabolic syndrome in rats via effects on PPAR, LXR, and SREBP signaling. J Nutr;139(8):1431-8. 2009-08-01 [PMID: 19515742]
Ouvrier A, Cadet R, Vernet P et al. LXR ABCA1 control cholesterol homeostasis in the proximal mouse epididymis in a cell specific manner. J Lipid Res :M800657-JLR800200. 2009-01-01 [PMID: 19395734] (IHC-P, WB, Mouse)	IHC-P, WB	Mouse
Bujold K, Rhainds D, Jossart C et al. CD36-mediated cholesterol efflux is associated with PPAR{gamma} activation via a MAPK-dependent COX-2 pathway in macrophages. Cardiovasc Res :cvp118. 2009-01-01 [PMID: 19377069]
Rohrer L, Ohnsorg PM, Lehner M et al. High-density lipoprotein transport through aortic endothelial cells involves scavenger receptor BI and ATP-binding cassette transporter G1. Circ Res 2009-05-22 [PMID: 19372466]
Sirek AS, Liu L, Naples M et al. Insulin stimulates the expression of Carbohydrate Response Element Binding Protein (ChREBP) by attenuating the repressive effect of POU homeodomain protein Oct-1. Endocrinology :en2008-1702. 2009-01-01 [PMID: 19359385]
Delvecchio CJ, Bilan P, Nair P et al. LXR-induced reverse cholesterol transport in human airway smooth muscle is mediated exclusively by ABCA1. Am J Physiol Lung Cell Mol Physiol;295(5):L949-57. 2008-11-01 [PMID: 18820007]
Nakanishi S, Vikstedt R, Soderlund S et al. Serum, but not monocyte macrophage foam cells derived from low HDL-C subjects, displays reduced cholesterol efflux capacity. J Lipid Res;50(2):183-92. 2009-02-01 [PMID: 18787236]
Mauldin JP et al. Reduced expression of ATP-binding cassette transporter G1 increases cholesterol accumulation in macrophages of patients with type 2 diabetes mellitus. Circulation;117(21):2785-92. 2008-05-27 [PMID: 18490524]
Lorenzi I, von Eckardstein A, Radosavljevic S, Rohrer L Lipidation of apolipoprotein A-I by ATP-binding cassette transporter (ABC) A1 generates an interaction partner for ABCG1 but not for scavenger receptor BI. Biochim Biophys Acta 2008-06-01 [PMID: 18485926]
Ouimet M, Wang M-D, Cadotte N et al. Epoxycholesterol Impairs Cholesteryl Ester Hydrolysis in Macrophage Foam Cells, Resulting in Decreased Cholesterol Efflux. Arterioscler Thromb Vasc Biol;28(6):1144-1150. 2008-01-01 [PMID: 18369155]
Wojcik AJ et al. A critical role for ABCG1 in macrophage inflammation and lung homeostasis. J Immunol;180(6):4273-82. 2008-03-15 [PMID: 18322240]
Burgess BL, Parkinson PF, Racke MM et al. ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo. J Lipid Res;49(6):1254-1267. 2008-01-01 [PMID: 18314463]
Wahrle SE, Jiang H, Parsadanian M et al. Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease. J Clin Invest 2008-02-01 [PMID: 18202749] (WB, Mouse)	WB	Mouse
Hu, W et al. Biogenesis of HDL by SAA is dependent on ABCA1 in the liver in vivo. J Lipid Res;49(2):386-93. 2008-02-01 [PMID: 18033752]
Zhou X et al. Genetic deletion of low density lipoprotein receptor impairs sterol-induced mouse macrophage ABCA1 expression. A new SREBP1-dependent mechanism. J Biol Chem. 283(4):2129-38. 2008-01-25 [PMID: 18029360]
Out, R et al. Coexistence of foam cells and hypocholesterolemia in mice lacking the ABC transporters A1 and G1. Circ Res;102(1):113-20. 2008-01-04 [PMID: 17967783]
Yvan-Charvet, L et al. SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL. J Lipid Res;49(1):107-14. 2008-01-01 [PMID: 17960026]
Tarr, PT et al. ABCG1 and ABCG4 are coexpressed in neurons and astrocytes of the CNS and regulate cholesterol homeostasis through SREBP-2. J Lipid Res;49(1):169-82. 2008-01-01 [PMID: 17916878]
Tansley, Gavin H et al. The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein. J Lipid Res;48(5):1022-34. 2007-05-01 [PMID: 17293612]
Wang, M et al. Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathways. J Lipid Res;48(3):633-45. 2007-03-01 [PMID: 17148552]
1 Li, T, Chen, W Chiang, JYL. PXR induces CYP27A1 regulates cholesterol metabolism in the intestine. J Lipid Res, 48, 373-384. 2007-01-01 [PMID: 17088262]
Ranalletta, M et al. Decreased atherosclerosis in low-density lipoprotein receptor knockout mice transplanted with Abcg1-/- bone marrow. Arterioscler Thromb Vasc Biol;26(10):2308-15. 2006-10-01 [PMID: 16917103]
Takata Y, Chu V, Collins AR et al. Transcriptional repression of ATP-binding cassette transporter A1 gene in macrophages: a novel atherosclerotic effect of angiotensin II. Circ Res 2005-10-28 [PMID: 16224068] (WB, Mouse)	WB	Mouse
Show All 177 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Angeliki Chroni	WB	Human	10/08/2014	View Summary Application Western Blot Sample Tested ABCG1 transfected HEK293 cell lysate and controls (untransfected cells) Species Human
	5 reviewed by: Verified Customer	WB	Mouse	08/26/2013	View Summary Application Western Blot Species Mouse

Array NB400-132

• ABCG1 Antibodies
• ABCG1 ELISA Kit
• ABCG1 Proteins