Home » XCL1/Lymphotactin » XCL1/Lymphotactin Antibodies » XCL1/Lymphotactin Antibody (109001)
Novus Biologicals products are now on bio-techne.com

XCL1/Lymphotactin Antibody (109001)

 (6 Publications)
 See All Related
Submit a Review

Images

 
There are currently no images for XCL1/Lymphotactin Antibody (MAB6951).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA(Cap)
Clone
109001
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB6951-SP
Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Novus Biologicals, part of Bio-Techne, offers 100% Guarantee

XCL1/Lymphotactin Antibody (109001) Summary

Immunogen
E. coli-derived recombinant human XCL1/Lymphotactin
Val22-Gly114
Accession # P47992
Specificity
Detects human XCL1/Lymphotactin in ELISAs and Western blots. In sandwich ELISAs, less than 0.15% cross-reactivity was observed with recombinant mouse MCP‑5, recombinant human (rh) MIP‑3 beta , rhGRO alpha , rhTGF‑ alpha , rhGRO gamma , rhActivin RII Fc Chimera, rhIGF‑II, or rhIL‑15.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
XCL1
Purity Statement
Protein A or G purified from ascites
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL
  • ELISA Standard (Matched Pair)
  • Western Blot 1 ug/mL
Application Notes
ELISA Detection: Human XCL1/Lymphotactin Biotinylated Antibody (Catalog number BAF695)
Standard: Recombinant Human XCL1/Lymphotactin (Catalog number 695-LT)
Publications
Read Publications using
MAB6951 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for XCL1/Lymphotactin Antibody (109001)

  • ATAC
  • ATACSmall-inducible cytokine C1
  • C motif chemokine 1
  • chemokine (C motif) ligand 1
  • Cytokine SCM-1
  • LPTNSCM-1-alpha
  • LTNXC chemokine ligand 1
  • Lymphotactin
  • lymphotaxin
  • SCM-1 alpha
  • SCM-1
  • SCM1A
  • SCM-1a
  • SCYC1SCM1
  • single cysteine motif 1a
  • small inducible cytokine subfamily C, member 1 (lymphotactin)
  • XCL1

Background

Human lymphotactin (Lptn)/XCL1 (also named human SCM-1 alpha and ATAC) and its mouse homologue belong to the C or gamma  subfamily of chemokines. The C chemokines lack two (the 1st and 3rd ) of the four invariant cysteine residues normally found in the CC and CXC chemokines and have an extended carboxy terminus. Human lymphotactin encodes a 114 amino acid residue precursor protein with a 21 amino acid residue predicted signal peptide. The expression of lymphotactin is abundant in some activated T cells such as activated CD8+ T cells and other class I MHC restricted T cells. Lptn expression is absent in CD4+ T cells. Human and mouse Lptn share approximately 60% amino acid sequence homology. The gene for lymphotactin has been mapped to chromosome 1 in both human and mouse. Recombinant human lymphotactin has been shown to have chemotactic activity for lymphocytes and NK cells. The orphan receptor GPR5 has been reported to be the specific receptor for Lptn.

  1. Kennedy, J. et al. (1995) J. Immunol. 155:203.
  2. Zlotnik, A. et al. (1999) Critical Reviews in Immunol. 19:1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

CCL5/RANTES [HRP]
DRN00B
N/A CCL5/RANTES [HRP]
N/A CCL5/RANTES [HRP]
N/A CCL5/RANTES [HRP]
(100 Publications)
Species: Hu
Applications: ELISA
CCL2/JE/MCP-1 [HRP]
DCP00
N/A CCL2/JE/MCP-1 [HRP]
N/A CCL2/JE/MCP-1 [HRP]
N/A CCL2/JE/MCP-1 [HRP]
(254 Publications)
Species: Hu
Applications: ELISA
CXCL10/IP-10/CRG-2
[HRP]
DIP100
N/A CXCL10/IP-10/CRG-2 [HRP]
N/A CXCL10/IP-10/CRG-2 [HRP]
N/A CXCL10/IP-10/CRG-2 [HRP]
(153 Publications)
Species: Hu
Applications: ELISA
IL-2 [Unconjugated]
202-IL
Bioactivity IL-2 [Unconjugated]
(4 Reviews)
(377 Publications)
Species: Hu
Applications: BA
Aromatase Antibody
NB100-1596
Western Blot Aromatase Antibody
Western Blot Aromatase Antibody
Immunohistochemistry-Paraffin Aromatase Antibody
(16 Publications)
Species: Hu, Mu, Pm, Rb, Rt
Applications: ICC/IF, IHC, IHC-P, Simple Western, WB
IFN-gamma
[Unconjugated]
285-IF
Bioactivity IFN-gamma [Unconjugated]
SDS-PAGE IFN-gamma [Unconjugated]
SEC-MALS IFN-gamma [Unconjugated]
(2 Reviews)
(450 Publications)
Species: Hu
Applications: BA
XCR1/CCXCR1
Antibody [Unconjugate
AF857
Flow Cytometry XCR1/CCXCR1 Antibody [Unconjugated]
Flow Cytometry XCR1/CCXCR1 Antibody [Unconjugated]
Species: Hu
Applications: CyTOF-ready, Flow, ICC, WB
TNF-alpha
[Unconjugated]
210-TA
SDS-PAGE TNF-alpha [Unconjugated]
Bioactivity TNF-alpha [Unconjugated]
SEC-MALS TNF-alpha [Unconjugated]
(3 Reviews)
(810 Publications)
Species: Hu
Applications: BA
IL-4 [Unconjugated]
6507-IL/CF
Bioactivity IL-4 [Unconjugated]
(3 Publications)
Species: Hu
Applications: BA
CD4 Antibody - BSA
Free
NBP1-19371
Immunohistochemistry-Frozen CD4 Antibody - BSA Free
Immunohistochemistry-Paraffin CD4 Antibody - BSA Free
Flow Cytometry CD4 Antibody - BSA Free
(9 Reviews)
(50 Publications)
Species: Ca, Hu, Mu, Po, Rb, Rt
Applications: Dual ISH-IHC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, Simple Western, WB
CD8 Antibody
(53-6.7) - BSA Free
NBP1-49045
Immunohistochemistry-Paraffin CD8 Antibody (53-6.7) - BSA Free
Immunocytochemistry/ Immunofluorescence CD8 Antibody (53-6.7) - BSA Free
Immunohistochemistry-Frozen CD8 Antibody (53-6.7) - BSA Free
(3 Reviews)
(28 Publications)
Species: Mu, Rt
Applications: Cell Depl, CyTOF-ready, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, InhibTFunc
CXCL8/IL-8
Antibody (6217) [Unco ...
MAB208
Neutralization CXCL8/IL-8 Antibody (6217) [Unconjugated]
Immunocytochemistry CXCL8/IL-8 Antibody (6217) [Unconjugated]
Western Blot CXCL8/IL-8 Antibody (6217) [Unconjugated]
(1 Review)
(182 Publications)
Species: Hu
Applications: CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), ICC, ICFlow, Neut, Simple Western, WB
CX3CL1/Fractalkine
Antibody [Unconjugate ...
AF365
Neutralization CX3CL1/Fractalkine Antibody [Unconjugated]
(2 Reviews)
(33 Publications)
Species: Hu
Applications: Neut, WB
IL-6 [HRP]
M6000B
N/A IL-6 [HRP]
N/A IL-6 [HRP]
N/A IL-6 [HRP]
(648 Publications)
Species: Mu
Applications: ELISA
CXCL9/MIG Antibody
[Unconjugated]
AF-492-NA
Neutralization CXCL9/MIG Antibody [Unconjugated]
Immunocytochemistry/ Immunofluorescence CXCL9/MIG Antibody [Unconjugated]
Western Blot CXCL9/MIG Antibody [Unconjugated]
(31 Publications)
Species: Mu
Applications: ELISA(Cap), ELISA(Det), ELISA(Sta), Neut
IL-10 [Biotin]
DY417
N/A IL-10 [Biotin]
(299 Publications)
Species: Mu
Applications: ELISA
CCL1/I-309/TCA-3
[Biotin]
DY272
N/A CCL1/I-309/TCA-3 [Biotin]
(12 Publications)
Species: Hu
Applications: ELISA
CCL11/Eotaxin [HRP]
MME00
N/A CCL11/Eotaxin [HRP]
N/A CCL11/Eotaxin [HRP]
(57 Publications)
Species: Mu
Applications: ELISA
Doublecortin
Antibody
NBP1-72042
Western Blot Doublecortin Antibody
Immunocytochemistry/ Immunofluorescence Doublecortin Antibody
Immunocytochemistry/ Immunofluorescence Doublecortin Antibody
(4 Publications)
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, PEP-ELISA, WB
XCL1/Lymphotactin
Antibody (109001)
MAB6951
XCL1/Lymphotactin Antibody (109001)
Species: Hu
Applications: WB, ELISA(Cap)

Publications for XCL1/Lymphotactin Antibody (MAB6951)(6)

We have publications tested in 2 confirmed species: Human, Virus - HIV-1.

We have publications tested in 4 applications: Capture Assay, Immunocytochemistry, Neutralization, Western Blot.


Filter By Application
Capture Assay
(1)
Immunocytochemistry
(1)
Neutralization
(1)
Western Blot
(1)
All Applications
Filter By Species
Human
(3)
Virus - HIV-1
(1)
All Species
Showing Publications 1 - 6 of 6.
Publications using MAB6951 Applications Species
Li, Q;Sharkey, A;Sheridan, M;Magistrati, E;Arutyunyan, A;Huhn, O;Sancho-Serra, C;Anderson, H;McGovern, N;Esposito, L;Fernando, R;Gardner, L;Vento-Tormo, R;Turco, MY;Moffett, A; Human uterine natural killer cells regulate differentiation of extravillous trophoblast early in pregnancy Cell stem cell 2024-01-10 [PMID: 38237587] (Immunocytochemistry, Human) Immunocytochemistry Human
Bérengère Salomé, John P. Sfakianos, Daniel Ranti, Jorge Daza, Christine Bieber, Andrew Charap et al. NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer Cancer Cell 9/1/2022 [PMID: 36099881]
Schwabenland M, SaliE H, Tanevski J et al. Deep spatial profiling of COVID19 brains reveals neuroinflammation by compartmentalized local immune cell interactions and targets for intervention Immunity 6/9/2021 [PMID: 34174183]
A Gudjonsson, A Lysén, S Balan, V Sundvold-G, C Arnold-Sch, L Richter, ES Bækkevold, M Dalod, B Bogen, E Fossum Targeting Influenza Virus Hemagglutinin to Xcr1(+) Dendritic Cells in the Absence of Receptor-Mediated Endocytosis Enhances Protective Antibody Responses J. Immunol, 2017-02-22;0(0):. 2017-02-22 [PMID: 28228559] (Neutralization, Human) Neutralization Human
Guzzo C, Fox J, Lin Y, Miao H, Cimbro R, Volkman B, Fauci A, Lusso P The CD8-derived chemokine XCL1/lymphotactin is a conformation-dependent, broad-spectrum inhibitor of HIV-1. PLoS Pathog, 2013-12-26;9(12):e1003852. 2013-12-26 [PMID: 24385911] (Capture Assay, Virus - HIV-1) Capture Assay Virus - HIV-1
Cao W, Tang S, Yuan H, Wang H, Zhao X, Lu H Mycobacterium tuberculosis antigen Wag31 induces expression of C-chemokine XCL2 in macrophages. Curr. Microbiol., 2008-07-11;57(3):189-94. 2008-07-11 [PMID: 18618175] (Western Blot, Human) Western Blot Human

Reviews for XCL1/Lymphotactin Antibody (MAB6951) (0)

There are no reviews for XCL1/Lymphotactin Antibody (MAB6951). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for XCL1/Lymphotactin Antibody (MAB6951) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional XCL1/Lymphotactin Products

Blogs on XCL1/Lymphotactin

There are no specific blogs for XCL1/Lymphotactin, but you can read our latest blog posts.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Western blot shows detection of Mouse Anti-Human/Mouse/Rat STAT3 Monoclonal Antibody (MAB1799) using a 1:1000 dilution of HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
Goat anti-Mouse IgG Secondary Antibody [HRP]
HAF007
SDS-Page: Mouse IgG1 Isotype Control (MG1) [NBP1-97005] - Lane 1: , Non-reduced. M: Opal Pre-stained Ladder. Lane 2: , Reduced. Load: 1.0 ug per lane. Predicted/Observed: 120 kDa Non-reduced, 55 and 25 Reduced.
Mouse IgG1 Isotype Control (MG1)
NBP1-97005-0.5mg

Contact Information

Product PDFs

  PDF SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our XCL1/Lymphotactin Antibody (109001) and receive a gift card or discount.


Bioinformatics

Gene Symbol XCL1
Uniprot