Ubiquitin Antibody (3E2-E6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 3 of 3.

Publications using H00006233-M01	Applications	Species
Han XJ, Lee MJ, Yu GR et al. Altered dynamics of ubiquitin hybrid proteins during tumor cell apoptosis. Cell Death Dis. 2012-01-19 [PMID: 22258406]
Fatima G, Mathan G, Kumar V. The HBx protein of hepatitis B virus regulates the expression, intracellular distribution and functions of Ribosomal Protein S27a. J Gen Virol. 2011-12-07 [PMID: 22158882]
Mathan G, Fatima G, Saxena AK et al. Chemoprevention with Aqueous Extract of Butea monosperma flowers results in normalization of nuclear morphometry and inhibition of a proliferation marker in liver tumors. Phytother Res. 2010-06-28 [PMID: 20669187]

Array H00006233-M01

• Ubiquitin Antibodies
• Ubiquitin Lysate
• Ubiquitin Proteins
• Ubiquitin Proteins and Enzymes