UBE2K/E2-25K Antibody (701316)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

UBE2K (Ubiquitin-conjugating enzyme E2; also E2-25K, HIP-2, UBE2K-25K and LIG) is a 24-26 kDa cytosolic member of the UBE family of proteins. It is widely expressed (in neurons, monocytes and neutrophils), and acts to ubiquitinate proteins targeted for degradation. UBE2K serves as an E2 ubiquitin conjugating enzyme with a preference for ubiquitin chain generation through Lys48. It appears to polyubiquitinate targets once they have been monoubiquitinated, and to act as either a monomer or dimer. Human UBE2K is 200 amino acids (aa) in length. It contains one UBA domain (aa 160-200). There are two potential splice variants that show a deletion of aa 22-72 and 134-176, respectively. Human and mouse UBE2K are identical in aa sequence.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Western Blot.

Showing Publication 1 - 1 of 1.

Publication using MAB6609	Applications	Species
Gupta N, Li W, Willard B, Silverstein R, McIntyre T Proteasome proteolysis supports stimulated platelet function and thrombosis. Arterioscler Thromb Vasc Biol, 2013-10-31;34(1):160-8. 2013-10-31 [PMID: 24177323] (Western Blot, Human)	Western Blot	Human

Array MAB6609

• UBE2K/E2-25K Antibodies
• UBE2K/E2-25K Lysate
• UBE2K/E2-25K Proteins
• UBE2K/E2-25K Proteins and Enzyme