Transportin 1 Antibody (D45) - BSA Free

Heterogeneous nuclear ribonucleoprotein hnRNPA1 is an abundant nuclear protein that plays an important role in pre-mRNA processing and mRNA export from the nucleus. A1 shuttles rapidly between the nucleus and the cytoplasm, and a 38-amino acid domain, M9, serves as the bi-directional transport signal of A1. Recently, a 90-kD protein, transportin, was identified as the mediator of A1 nuclear import. Transportin mediates the nuclear import of additional hnRNP proteins, including hnRNPF. The nuclear localization of A1 is dependent on ongoing RNA polymerase II transcription.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 4 applications: ICC/IF, IHC-P, IP, WB.

Showing Publications 1 - 8 of 8.

Publications using NB600-1397	Applications	Species
Stang TE, Salapa HE, Clarke JWE et al. Heterogeneous Nuclear Ribonucleoprotein A1 Knockdown Alters Constituents of Nucleocytoplasmic Transport Brain Sciences 2024-10-19 [PMID: 39452051]
Fare CM, Rhine K, Lam A et al. A minimal construct of nuclear-import receptor Karyopherin-beta 2 defines the regions critical for chaperone and disaggregation activity The Journal of biological chemistry 2022-12-15 [PMID: 36529289] (WB, Human)	WB	Human
Vieira NM, Naslavsky MS, Licinio L et al. A defect in the RNA-processing protein HNRPDL causes limb-girdle muscular dystrophy 1G (LGMD1G). Hum. Mol. Genet. 2014-03-18 [PMID: 24647604] (IHC-P, Human)	IHC-P	Human
Suzuki M, Iijima M, Nishimura A et al. Two separate regions essential for nuclear import of the hnRNP D nucleocytoplasmic shuttling sequence. FEBS J. 2005-08-01 [PMID: 16045768] (WB, Human)	WB	Human
Allemand E, Guil S, Myers M et al. Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shock. Proc Natl Acad Sci U S A. 2005-03-08 [PMID: 15738418] (WB, Mouse)	WB	Mouse
Kawamura H, Tomozoe Y, Akagi T et al. Identification of the nucleocytoplasmic shuttling sequence of heterogeneous nuclear ribonucleoprotein D-like protein JKTBP and its interaction with mRNA. J Biol Chem. 2002-01-25 [PMID: 11705999] (WB, Human)	WB	Human
Siomi MC, Eder PS, Kataoka N et al. Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins. J Cell Biol. 1997-09-22 [PMID: 9298975] (ICC/IF, WB, IP, Human)	ICC/IF, WB, IP	Human
Korobeynikov V Therapeutic strategies targeting FUS toxicity in amyotrophic lateral sclerosis: from a novel mouse model of disease to a first-in-human study Thesis 2021-01-01 (WB, Mouse)	WB	Mouse

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Pauline Jeannot	WB	Human	02/06/2019	View Summary Application Western Blot Sample Tested human lung cancer cell line Species Human Lot A1

Array NB600-1397

• Transportin 1 Antibodies
• Transportin 1 ELISA Kits
• Transportin 1 Protein